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** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **
Moderate Drinking During Early Pregnancy Is OK
http://mnt.to/a/46PH
Mothers to be around the world can relax a little. A new Danish study showed that low and moderate drinking during early pregnancy does not have noticeable adverse effects on children after they are born.
Value Of Liver Cancer Screening Doubtful Says Danish Study
http://mnt.to/a/46NQ
A new study from Denmark finds that people with alcoholic cirrhosis are no more likely to die from liver cancer than other people. The researchers conclude screening such patients is unlikely to save lives and would not be cost-effective.
Moderate Consumption Of Alcohol In Early Pregnancy Has No Adverse Effects On Children Aged 5
http://mnt.to/a/46NK
Low and moderate weekly alcohol consumption in early pregnancy is not associated with adverse neuropsychological effects in children aged five, suggests a series of papers published today (20 June) in BJOG: An International Journal of Obstetrics and Gynaecology.
Vaccine Negates Effects Of Cocaine In Mice
http://mnt.to/a/46MX
A single-dose vaccine capable of providing immunity against the effects of cocaine offers a novel and groundbreaking strategy for treating cocaine addiction is described in an article published Instant Online in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.
Medical Marijuana Not Found To Increase Teen Drug Use
http://mnt.to/a/46ML
While marijuana use by teens has been increasing since 2005, an analysis of data from 1993 through 2009 by economists at three universities has found no evidence to link the legalization of medical marijuana to increased use of the drug among high school students.
Adults Agree On Top Children's Health Issues Regardless Of Political Party Affiliation: Childhood Obesity, Bullying
http://mnt.to/a/46MJ
During this presidential election season, there will be plenty of debate between the candidates on the issues. But when it comes to childhood health concerns, a new poll shows many adults agree on the top priorities they want to see the candidates address: childhood obesity and bullying.
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** ALLERGY News **
Protection Against Respiratory Infection Linked To Asthma From Dog-Associated House Dust
http://mnt.to/a/46ND
House dust from homes with dogs appears to protect against infection with a common respiratory virus that is associated with the development of asthma in children. Researchers from the University of California, San Francisco, present their findings today at the 2012 General Meeting of the American Society for Microbiology.
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** BIOLOGY / BIOCHEMISTRY News **
How Protein Clumps Are Pulled Apart
http://mnt.to/a/46PM
Amyloid fibers are protein aggregates, and although they are associated to many neurodegenerative diseases, such as Parkinson's disease, they can also play beneficial, protective roles. In yeast, for example, these fibers are associated with evolution and increased survival.
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** BLOOD / HEMATOLOGY News **
Surprisingly High Untreated Kidney Failure Among Adults
http://mnt.to/a/46Ns
JAMA publishes an article today (20th June), showing a surprisingly high rate of untreated kidney failure amongst adults. The study involved nearly 2 million adults in Canada and the rate was considerably higher amongst older adults.
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** BONES / ORTHOPEDICS News **
New Clinical Practice Guidelines On The Management Of Osteoporosis In Men
http://mnt.to/a/46MH
Osteoporosis in men causes significant morbidity and mortality. The Endocrine Society has released clinical practice guidelines (CPG) for management of this condition in men. "Osteoporosis in Men: An Endocrine Society Clinical Practice Guideline," is published in the June 2012 issue of the Journal of Clinical Endocrinology and Metabolism (JCEM), a publication of The Endocrine Society.
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** BREAST CANCER News **
Breast Cancer Screening Should Start At 40, Says American Medical Association
http://mnt.to/a/46PS
Women, when they reach 40 years of age, should be eligible for screening mammography, and should have that screening covered by insurance, says the American Medical Association (AMA), in what it describes as a recommendation update.
When Does Breast Cancer Spread?
http://mnt.to/a/46PG
According to a study published in the Medical Journal of Australia, important information regarding prognosis can now be given to women who are diagnosed with early breast cancer. Dr Sarah Lord from the NHMRC Clinical Trials Center at the University of Sydney and her team note that in Australia, 1 in 10 women diagnosed with non-metastatic breast cancer will develop metastatic cancer within five years.
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** CANCER / ONCOLOGY News **
Value Of Liver Cancer Screening Doubtful Says Danish Study
http://mnt.to/a/46NQ
A new study from Denmark finds that people with alcoholic cirrhosis are no more likely to die from liver cancer than other people. The researchers conclude screening such patients is unlikely to save lives and would not be cost-effective.
How The Key Enzyme Involved In Aging, Cancer Assembles
http://mnt.to/a/46MY
UCLA biochemists have mapped the structure of a key protein-RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging.The researchers found that a region at the end of the p65 protein that includes a flexible tail is responsible for bending telomerase's RNA backbone in order to create a scaffold for the assembly of other protein building blocks.
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** CARDIOVASCULAR / CARDIOLOGY News **
Cardiovascular Death Risk Linked With Living Solo
http://mnt.to/a/46Nm
According to a recent study published in Archives of Internal Medicine, people living alone, who have arterial vascular disease, have a greater chance of dying from cardiovascular health problems than those living with other people.
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** CAREGIVERS / HOMECARE News **
Caring For The Elderly Within UK Bangladeshi And Pakistani Communities
http://mnt.to/a/46MM
Over the next 20 years the proportion of older people living within the Bangladeshi and Pakistani communities in the UK will increase significantly. Most expect that their immediate family, particularly female family members, will provide the majority of care for them in their old age, according to new research funded by the Economic and Social Research Council (ESRC).
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** CONFERENCES News **
Best Practices In Specialty Product Launch & Lifecycle Management Conference, 24-25 September 2012, Brussels
http://mnt.to/a/46PF
This will be a very unique event that will provide participants with a broad overview on the best practices towards launch excellence and lifecycle management of pharmaceutical products in developed and emerging markets.
Drug Delivery Technologies Show Promise Of Improving Clinical Outcomes For Patients At Partnership Opportunities In Drug Delivery Conference
http://mnt.to/a/46PD
In an effort to remove barriers and embrace collaborations to get therapeutics to patients faster, pharmaceutical and biotech companies will listen to more than 25 drug delivery technology presentations, ranging from novel delivery devices to formulation technologies at the 2nd Annual PODD: Partnership Opportunities in Drug Delivery conference, October 1-2, 2012, at the Boston Park Plaza hotel in Boston, MA.
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** CROHN'S / IBD News **
Beating Urinary Tract Infections In Mouse Model
http://mnt.to/a/46MS
Scientists at Washington University School of Medicine in St. Louis have found new clues to why some urinary tract infections recur persistently after multiple rounds of treatment.Their research, conducted in mice, suggests that the bacteria that cause urinary tract infections take advantage of a cellular waste disposal system that normally helps fight invaders.
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** DIABETES News **
More Americans Facing Blindness
http://mnt.to/a/46PN
A study from Johns Hopkins University is showing an increasing number of vision impairment problems and blindness in those over 40. The report released today by Prevent Blindness America and the National Eye Institute (NEI) shows a surprising 23% increase since 2000.
Malaria's Spread May Be Encouraged By Rising Type 2 Diabetes Prevalence
http://mnt.to/a/46PC
The mosquito's immune system is suppressed by human insulin, which could be bad news for the spread of malaria if the number of people in Africa with diabetes type 2 continues to grow at its present rate, researchers from the University of California, Davis, explained in the journal Infection and Immunity.
Cancer Stem Cell Death In Pancreatic Cancer Cell Lines Caused By Metformin Treatment
http://mnt.to/a/46Nx
Results of some preclinical trials have shown that low doses of the antidiabetic drug metformin may effectively destroy cancer stem cells, a group of cells that are considered to be responsible for tumor initiation and, because they are resistant to standard chemotherapies, tumor relapse.
RLIP76 Contributes To Pancreatic Cancer Cell Resistance To Chemotherapy And Radiation
http://mnt.to/a/46N8
Researchers at the City of Hope Comprehensive Cancer Center have not only identified a protein that allows pancreatic cancer cells to resist therapy but also developed a way to block it, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
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** EYE HEALTH / BLINDNESS News **
More Americans Facing Blindness
http://mnt.to/a/46PN
A study from Johns Hopkins University is showing an increasing number of vision impairment problems and blindness in those over 40. The report released today by Prevent Blindness America and the National Eye Institute (NEI) shows a surprising 23% increase since 2000.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Commensal Bacteria Help Fight Viruses
http://mnt.to/a/46MT
Healthy humans harbor an enormous and diverse group of bacteria and other bugs that live within their intestines. These microbial partners provide beneficial aid in multiple ways - from helping digest food to the development of a healthy immune system.
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** GENETICS News **
Association Between Genetic Marker In Vitamin D Receptor Gene And Increased Pancreatic Cancer Survival
http://mnt.to/a/46Nw
Pancreatic cancer patients with a genetic marker linked to increased expression of the receptor for vitamin D have higher rates of overall survival, according to findings presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
How The Key Enzyme Involved In Aging, Cancer Assembles
http://mnt.to/a/46MY
UCLA biochemists have mapped the structure of a key protein-RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging.The researchers found that a region at the end of the p65 protein that includes a flexible tail is responsible for bending telomerase's RNA backbone in order to create a scaffold for the assembly of other protein building blocks.
Vaccine Negates Effects Of Cocaine In Mice
http://mnt.to/a/46MX
A single-dose vaccine capable of providing immunity against the effects of cocaine offers a novel and groundbreaking strategy for treating cocaine addiction is described in an article published Instant Online in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.
Identification Of New Cerebellar Ataxia Gene In Dogs Offers Novel Candidate Gene In Human Early-Onset Degenerative Ataxias
http://mnt.to/a/46MN
Researchers at the University of Helsinki and the Folkhalsan Research Center, Finland, have identified the genetic cause of early-onset progressive cerebellar degeneration in the Finnish Hound dog breed.
Possible Approaches To Protect Those At Risk For Huntington's Disease
http://mnt.to/a/46MG
In Huntington's disease, abnormally long strands of glutamine in the huntingtin (Htt) protein, called polyglutamines, cause subtle changes in cellular functions that lead to neurodegeneration and death.
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** HEART DISEASE News **
Chronic Kidney Disease And Heart Attack Risk
http://mnt.to/a/46PR
An article published Online First in The Lancet reveals that the risk of coronary heart disease in patients with chronic kidney disease is as high as that of patients who had a previous heart attack.
Heart Disease Patients Benefit From Online Treatment
http://mnt.to/a/46PQ
A new study reveals that patients with vascular disease have an elevated risk of experiencing a further event or death. Evidence shows that the risk can be effectively reduced by nurse practitioners that treat any vascular risk factors.
Chest Pain And Heart Disease Risk - New Scoring System
http://mnt.to/a/46PP
A study featured in BMJ (British Medical Journal) reveals that it is possible to identify patients with a high risk of coronary artery disease, who may require further diagnostic work, by using a new risk prediction tool, which is more accurate than existing models, and which can easily be integrated into electronic patient records or mobile applications.
Opening The Door For Use Of Cardiac Stem Cell Patches In Disease Research, Testing Of New Drug Treatments, Therapies To Repair Damaged Heart Muscle
http://mnt.to/a/46Nb
A cutting-edge method developed at the University of Michigan Center for Arrhythmia Research successfully uses stem cells to create heart cells capable of mimicking the heart's crucial squeezing action.
For Heart Transplant Patients Whose Arteries Reclose After Stenting, Survival Rates Are Lower
http://mnt.to/a/46MQ
Heart transplant patients are notorious for developing an aggressive form of coronary artery disease that can often result in heart failure, death or the need for repeat transplantation. The condition can also have a negative impact on future cardiac procedures, such as stenting.
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** HUNTINGTONS DISEASE News **
Possible Approaches To Protect Those At Risk For Huntington's Disease
http://mnt.to/a/46MG
In Huntington's disease, abnormally long strands of glutamine in the huntingtin (Htt) protein, called polyglutamines, cause subtle changes in cellular functions that lead to neurodegeneration and death.
Huntington's Disease Patients May Benefit From Device Implanted In Brain
http://mnt.to/a/46MD
Studies suggest that neurotrophic factors, which play a role in the development and survival of neurons, have significant therapeutic and restorative potential for neurologic diseases such as Huntington's disease.
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** HYPERTENSION News **
Kids In Hospital With High Blood Pressure Double In Ten Years, US
http://mnt.to/a/46Nc
The number of children seen as inpatients in US hospitals nearly doubled in the ten years leading up to 2006, according to a new study published online in the journal Hypertension this week that also drew attention to the associated dramatic increase in healthcare cost.
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** IMMUNE SYSTEM / VACCINES News **
Vaccine Negates Effects Of Cocaine In Mice
http://mnt.to/a/46MX
A single-dose vaccine capable of providing immunity against the effects of cocaine offers a novel and groundbreaking strategy for treating cocaine addiction is described in an article published Instant Online in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.
Commensal Bacteria Help Fight Viruses
http://mnt.to/a/46MT
Healthy humans harbor an enormous and diverse group of bacteria and other bugs that live within their intestines. These microbial partners provide beneficial aid in multiple ways - from helping digest food to the development of a healthy immune system.
The STING Protein's Crucial Immune Fighter Role
http://mnt.to/a/46MP
Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.In the journal Molecular Cell, scientists describe the double wing-like crystal structure of this key protein, known as STING, which is a soldier on the front-line of the body's defense against pathogens.
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** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
What Is Leptospirosis? What Causes Leptospirosis?
http://mnt.to/a/46Pm
Leptospirosis is a fairly uncommon bacterial infection caused by a strain of Leptospira. It is most commonly transmitted from animals to humans when people with unhealed breaks in the skin, come into contact with water or soil that has been contaminated with animal urine - the bacterium can also enter the body through the eyes or mucous membranes.
Among University Students, Asymptomatic Rhinovirus Infection Outnumbers Symptomatic Infection 4 To 1
http://mnt.to/a/46NC
The common cold virus may be more common than previously thought in university students not reporting any symptoms. Rhinovirus, the virus responsible for the common cold was found at some point during an 8-week study period in an estimated 60% of university students that were asymptomatic.
Commensal Bacteria Help Fight Viruses
http://mnt.to/a/46MT
Healthy humans harbor an enormous and diverse group of bacteria and other bugs that live within their intestines. These microbial partners provide beneficial aid in multiple ways - from helping digest food to the development of a healthy immune system.
Beating Urinary Tract Infections In Mouse Model
http://mnt.to/a/46MS
Scientists at Washington University School of Medicine in St. Louis have found new clues to why some urinary tract infections recur persistently after multiple rounds of treatment.Their research, conducted in mice, suggests that the bacteria that cause urinary tract infections take advantage of a cellular waste disposal system that normally helps fight invaders.
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** IT / INTERNET / E-MAIL News **
Heart Disease Patients Benefit From Online Treatment
http://mnt.to/a/46PQ
A new study reveals that patients with vascular disease have an elevated risk of experiencing a further event or death. Evidence shows that the risk can be effectively reduced by nurse practitioners that treat any vascular risk factors.
----------------------------------------------
** LIVER DISEASE / HEPATITIS News **
Value Of Liver Cancer Screening Doubtful Says Danish Study
http://mnt.to/a/46NQ
A new study from Denmark finds that people with alcoholic cirrhosis are no more likely to die from liver cancer than other people. The researchers conclude screening such patients is unlikely to save lives and would not be cost-effective.
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** LYMPHOMA / LEUKEMIA / MYELOMA News **
Leukemia Patients 16 To 39 Have Higher Long-Term Survival Rates With Pediatric Regime Of Chemotherapy
http://mnt.to/a/46MF
Acute lymphoblastic leukemia (ALL), usually found in pediatric patients, is far more rare and deadly in adolescent and adult patients. According to the National Marrow Donor Program, child ALL patients have a higher than 80 percent remission rate, while the recovery rate for adults stands at only 40 percent.
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** MEDICAL DEVICES / DIAGNOSTICS News **
Potential Biomarker Diagnostic For Pancreatic Cancer
http://mnt.to/a/46Ny
The development of a highly accurate, blood-based pancreatic adenocarcinoma screen that would be accurate enough to test the general population for this deadly disease may not be far out of reach, according to data presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21, 2012.
Huntington's Disease Patients May Benefit From Device Implanted In Brain
http://mnt.to/a/46MD
Studies suggest that neurotrophic factors, which play a role in the development and survival of neurons, have significant therapeutic and restorative potential for neurologic diseases such as Huntington's disease.
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** MEDICAL STUDENTS / TRAINING News **
Concern For Patients, Colleagues Motivates Health Professionals To Work When Sick
http://mnt.to/a/46MW
An unwavering work ethic is a hallmark of many health professionals. But a new survey finds that when a doctor is sick, staunch dedication can have unintended consequences.A poll of 150 attendees of an American College of Physicians meeting in 2010 revealed that more than half of resident physicians had worked with flu-like symptoms at least once in the last year.
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** MELANOMA / SKIN CANCER News **
Risk For Pancreatic Cancer Reduced By Sun Exposure And Sun-Sensitive Skin Type
http://mnt.to/a/46N6
High levels of ultraviolet radiation at an individual's birth location, sun-sensitive skin type and a history of skin cancer each decreased risk for pancreatic cancer, according to study results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
New American Chemical Society Video On Sunscreens
http://mnt.to/a/46N3
Just in time for summer, the American Chemical Society's (ACS') award-winning Bytesize Science video series is offering a new episode on the chemistry of the sunscreen products that millions of people will slather on their skin during the warm months ahead.
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** MEN'S HEALTH News **
Prostate Cancer Risk Higher For Heavy Tea Drinkers
http://mnt.to/a/46Nt
A new study from Scotland has found that men who are heavy tea drinkers may be at higher risk for prostate cancer. However, the researchers point out their study was not designed to find causes, so all they can say is that heavy tea drinking is linked to a higher risk for prostate cancer and not necessarily the cause of it.
New Clinical Practice Guidelines On The Management Of Osteoporosis In Men
http://mnt.to/a/46MH
Osteoporosis in men causes significant morbidity and mortality. The Endocrine Society has released clinical practice guidelines (CPG) for management of this condition in men. "Osteoporosis in Men: An Endocrine Society Clinical Practice Guideline," is published in the June 2012 issue of the Journal of Clinical Endocrinology and Metabolism (JCEM), a publication of The Endocrine Society.
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** MENTAL HEALTH News **
Teenage Mothers In Canada At Greater Risk Of Abuse, Depression Than Older Mothers
http://mnt.to/a/46MV
Teen mothers are far more likely to suffer abuse and postpartum depression than older moms, according to a study of Canadian women's maternity experiences by a University of Alberta researcher.
Brain Development Should Be Taken Into Account When Criminal Law Involves Children
http://mnt.to/a/46MK
The legal system needs to take greater account of new discoveries in neuroscience that show how a difficult childhood can affect the development of a young person's brain which can increase the risk of adolescent crimes, according to researchers.
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** NEUROLOGY / NEUROSCIENCE News **
Sleep Regulation Influenced By Dopamine Levels
http://mnt.to/a/46PL
According to a study published in the journal PLoS Biology, dopamine, a neurotransmitter that helps controls the brain's reward and pleasure centers, also plays a role in sleep regulation.The study was conducted by researchers from CIBERNED (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas), dependant on the Spanish Ministry of Economy and Competitiveness through the Carlos III Health Institute, and from the Faculty of Biology of the University of Barcelona.
Peripheral Nervous System Damage - Therapy Shows Promise
http://mnt.to/a/46PJ
According to a study published online by the Journal of Neuroscience, researchers have gained new insight into how Schwann cells protect and repair damage caused by trauma and disease. These findings could lead to future treatments for the repair and improvement of damage to the peripheral nervous system.
In Challenge To Preferred Target Of Deep Brain Stimulation For Parkinson's, A Call For More Research
http://mnt.to/a/46Pk
When a neurologist and neurosurgeon believe deep brain stimulation may help a patient suffering from Parkinson's disease they target either of two structures - the internal globus pallidus or the subthalamic nucleus - in an area of the brain that controls voluntary muscle movements.
Dopamine And Sleep Regulation
http://mnt.to/a/46NB
A group of Spanish researchers has discovered a new function of the neurotransmitter dopamine in controlling sleep regulation. Dopamine acts in the pineal gland, which is central to dictating the 'circadian rhythm' in humans - the series of biological processes that enables brain activity to adapt to the time of the day (that is, light and dark cycles).
Identification Of New Cerebellar Ataxia Gene In Dogs Offers Novel Candidate Gene In Human Early-Onset Degenerative Ataxias
http://mnt.to/a/46MN
Researchers at the University of Helsinki and the Folkhalsan Research Center, Finland, have identified the genetic cause of early-onset progressive cerebellar degeneration in the Finnish Hound dog breed.
Huntington's Disease Patients May Benefit From Device Implanted In Brain
http://mnt.to/a/46MD
Studies suggest that neurotrophic factors, which play a role in the development and survival of neurons, have significant therapeutic and restorative potential for neurologic diseases such as Huntington's disease.
----------------------------------------------
** NUTRITION / DIET News **
Association Between Genetic Marker In Vitamin D Receptor Gene And Increased Pancreatic Cancer Survival
http://mnt.to/a/46Nw
Pancreatic cancer patients with a genetic marker linked to increased expression of the receptor for vitamin D have higher rates of overall survival, according to findings presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
Prostate Cancer Risk Higher For Heavy Tea Drinkers
http://mnt.to/a/46Nt
A new study from Scotland has found that men who are heavy tea drinkers may be at higher risk for prostate cancer. However, the researchers point out their study was not designed to find causes, so all they can say is that heavy tea drinking is linked to a higher risk for prostate cancer and not necessarily the cause of it.
Possible Approaches To Protect Those At Risk For Huntington's Disease
http://mnt.to/a/46MG
In Huntington's disease, abnormally long strands of glutamine in the huntingtin (Htt) protein, called polyglutamines, cause subtle changes in cellular functions that lead to neurodegeneration and death.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
Minimally Invasive Bariatric Procedures Safer And Cheaper Than Open Surgery
http://mnt.to/a/46PK
Laparoscopic Roux-en-Y gastric bypass procedures are safer and cheaper than open surgery procedures, researchers from Stanford University Medical Center reported in the journal Archives of Surgery.
Adults Agree On Top Children's Health Issues Regardless Of Political Party Affiliation: Childhood Obesity, Bullying
http://mnt.to/a/46MJ
During this presidential election season, there will be plenty of debate between the candidates on the issues. But when it comes to childhood health concerns, a new poll shows many adults agree on the top priorities they want to see the candidates address: childhood obesity and bullying.
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** PAIN / ANESTHETICS News **
In Pancreatic Cancer Model Nerve Growth Factors Elevated
http://mnt.to/a/46N4
Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancreatic cancer.
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** PANCREATIC CANCER News **
Pancreatic Cancer Patients Benefit From Erlotinib Added To Bevacizumab/Chemoradiotherapy Regimen
http://mnt.to/a/46Nz
The addition of high doses of erlotinib to the treatment regimen of bevacizumab and capecitabine with radiotherapy seems to benefit patients with locally advanced pancreatic cancer, according to results of a phase I study presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
Potential Biomarker Diagnostic For Pancreatic Cancer
http://mnt.to/a/46Ny
The development of a highly accurate, blood-based pancreatic adenocarcinoma screen that would be accurate enough to test the general population for this deadly disease may not be far out of reach, according to data presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21, 2012.
Cancer Stem Cell Death In Pancreatic Cancer Cell Lines Caused By Metformin Treatment
http://mnt.to/a/46Nx
Results of some preclinical trials have shown that low doses of the antidiabetic drug metformin may effectively destroy cancer stem cells, a group of cells that are considered to be responsible for tumor initiation and, because they are resistant to standard chemotherapies, tumor relapse.
Association Between Genetic Marker In Vitamin D Receptor Gene And Increased Pancreatic Cancer Survival
http://mnt.to/a/46Nw
Pancreatic cancer patients with a genetic marker linked to increased expression of the receptor for vitamin D have higher rates of overall survival, according to findings presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
Human Pancreatic Tumor Growth In Hypoxic Xenografts Reduced By A Combination Of TH-302 And Radiation
http://mnt.to/a/46Nv
A combination of the prodrug TH-302 and radiation may provide an effective treatment strategy for pancreatic cancer, according to preclinical results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
RLIP76 Contributes To Pancreatic Cancer Cell Resistance To Chemotherapy And Radiation
http://mnt.to/a/46N8
Researchers at the City of Hope Comprehensive Cancer Center have not only identified a protein that allows pancreatic cancer cells to resist therapy but also developed a way to block it, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
New Combo Treatment Offers Hope For Pancreatic Cancer Patients
http://mnt.to/a/46N7
Combining a new targeted therapy with standard chemotherapy may help defeat pancreatic cancer, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
Risk For Pancreatic Cancer Reduced By Sun Exposure And Sun-Sensitive Skin Type
http://mnt.to/a/46N6
High levels of ultraviolet radiation at an individual's birth location, sun-sensitive skin type and a history of skin cancer each decreased risk for pancreatic cancer, according to study results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
In Pancreatic Cancer Model Nerve Growth Factors Elevated
http://mnt.to/a/46N4
Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancreatic cancer.
----------------------------------------------
** PARKINSON'S DISEASE News **
In Challenge To Preferred Target Of Deep Brain Stimulation For Parkinson's, A Call For More Research
http://mnt.to/a/46Pk
When a neurologist and neurosurgeon believe deep brain stimulation may help a patient suffering from Parkinson's disease they target either of two structures - the internal globus pallidus or the subthalamic nucleus - in an area of the brain that controls voluntary muscle movements.
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** PEDIATRICS / CHILDREN'S HEALTH News **
Moderate Consumption Of Alcohol In Early Pregnancy Has No Adverse Effects On Children Aged 5
http://mnt.to/a/46NK
Low and moderate weekly alcohol consumption in early pregnancy is not associated with adverse neuropsychological effects in children aged five, suggests a series of papers published today (20 June) in BJOG: An International Journal of Obstetrics and Gynaecology.
Protection Against Respiratory Infection Linked To Asthma From Dog-Associated House Dust
http://mnt.to/a/46ND
House dust from homes with dogs appears to protect against infection with a common respiratory virus that is associated with the development of asthma in children. Researchers from the University of California, San Francisco, present their findings today at the 2012 General Meeting of the American Society for Microbiology.
Kids In Hospital With High Blood Pressure Double In Ten Years, US
http://mnt.to/a/46Nc
The number of children seen as inpatients in US hospitals nearly doubled in the ten years leading up to 2006, according to a new study published online in the journal Hypertension this week that also drew attention to the associated dramatic increase in healthcare cost.
Teenage Mothers In Canada At Greater Risk Of Abuse, Depression Than Older Mothers
http://mnt.to/a/46MV
Teen mothers are far more likely to suffer abuse and postpartum depression than older moms, according to a study of Canadian women's maternity experiences by a University of Alberta researcher.
The Health Effects Of Social-Class Discrimination On Teens
http://mnt.to/a/46MR
Discrimination felt by teenagers based on their social class background can contribute to physiologic changes associated with poorer health, according to a new study published online in Psychological Science, a journal of the Association for Psychological Science.
Medical Marijuana Not Found To Increase Teen Drug Use
http://mnt.to/a/46ML
While marijuana use by teens has been increasing since 2005, an analysis of data from 1993 through 2009 by economists at three universities has found no evidence to link the legalization of medical marijuana to increased use of the drug among high school students.
Brain Development Should Be Taken Into Account When Criminal Law Involves Children
http://mnt.to/a/46MK
The legal system needs to take greater account of new discoveries in neuroscience that show how a difficult childhood can affect the development of a young person's brain which can increase the risk of adolescent crimes, according to researchers.
Adults Agree On Top Children's Health Issues Regardless Of Political Party Affiliation: Childhood Obesity, Bullying
http://mnt.to/a/46MJ
During this presidential election season, there will be plenty of debate between the candidates on the issues. But when it comes to childhood health concerns, a new poll shows many adults agree on the top priorities they want to see the candidates address: childhood obesity and bullying.
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** PREGNANCY / OBSTETRICS News **
Moderate Drinking During Early Pregnancy Is OK
http://mnt.to/a/46PH
Mothers to be around the world can relax a little. A new Danish study showed that low and moderate drinking during early pregnancy does not have noticeable adverse effects on children after they are born.
Moderate Consumption Of Alcohol In Early Pregnancy Has No Adverse Effects On Children Aged 5
http://mnt.to/a/46NK
Low and moderate weekly alcohol consumption in early pregnancy is not associated with adverse neuropsychological effects in children aged five, suggests a series of papers published today (20 June) in BJOG: An International Journal of Obstetrics and Gynaecology.
Teenage Mothers In Canada At Greater Risk Of Abuse, Depression Than Older Mothers
http://mnt.to/a/46MV
Teen mothers are far more likely to suffer abuse and postpartum depression than older moms, according to a study of Canadian women's maternity experiences by a University of Alberta researcher.
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** PRIMARY CARE / GENERAL PRACTICE News **
Concern For Patients, Colleagues Motivates Health Professionals To Work When Sick
http://mnt.to/a/46MW
An unwavering work ethic is a hallmark of many health professionals. But a new survey finds that when a doctor is sick, staunch dedication can have unintended consequences.A poll of 150 attendees of an American College of Physicians meeting in 2010 revealed that more than half of resident physicians had worked with flu-like symptoms at least once in the last year.
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** PROSTATE / PROSTATE CANCER News **
Prostate Cancer Risk Higher For Heavy Tea Drinkers
http://mnt.to/a/46Nt
A new study from Scotland has found that men who are heavy tea drinkers may be at higher risk for prostate cancer. However, the researchers point out their study was not designed to find causes, so all they can say is that heavy tea drinking is linked to a higher risk for prostate cancer and not necessarily the cause of it.
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** PSYCHOLOGY / PSYCHIATRY News **
The Health Effects Of Social-Class Discrimination On Teens
http://mnt.to/a/46MR
Discrimination felt by teenagers based on their social class background can contribute to physiologic changes associated with poorer health, according to a new study published online in Psychological Science, a journal of the Association for Psychological Science.
Brain Development Should Be Taken Into Account When Criminal Law Involves Children
http://mnt.to/a/46MK
The legal system needs to take greater account of new discoveries in neuroscience that show how a difficult childhood can affect the development of a young person's brain which can increase the risk of adolescent crimes, according to researchers.
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** PUBLIC HEALTH News **
Risk For Pancreatic Cancer Reduced By Sun Exposure And Sun-Sensitive Skin Type
http://mnt.to/a/46N6
High levels of ultraviolet radiation at an individual's birth location, sun-sensitive skin type and a history of skin cancer each decreased risk for pancreatic cancer, according to study results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
New American Chemical Society Video On Sunscreens
http://mnt.to/a/46N3
Just in time for summer, the American Chemical Society's (ACS') award-winning Bytesize Science video series is offering a new episode on the chemistry of the sunscreen products that millions of people will slather on their skin during the warm months ahead.
Concern For Patients, Colleagues Motivates Health Professionals To Work When Sick
http://mnt.to/a/46MW
An unwavering work ethic is a hallmark of many health professionals. But a new survey finds that when a doctor is sick, staunch dedication can have unintended consequences.A poll of 150 attendees of an American College of Physicians meeting in 2010 revealed that more than half of resident physicians had worked with flu-like symptoms at least once in the last year.
The Health Effects Of Social-Class Discrimination On Teens
http://mnt.to/a/46MR
Discrimination felt by teenagers based on their social class background can contribute to physiologic changes associated with poorer health, according to a new study published online in Psychological Science, a journal of the Association for Psychological Science.
Caring For The Elderly Within UK Bangladeshi And Pakistani Communities
http://mnt.to/a/46MM
Over the next 20 years the proportion of older people living within the Bangladeshi and Pakistani communities in the UK will increase significantly. Most expect that their immediate family, particularly female family members, will provide the majority of care for them in their old age, according to new research funded by the Economic and Social Research Council (ESRC).
Medical Marijuana Not Found To Increase Teen Drug Use
http://mnt.to/a/46ML
While marijuana use by teens has been increasing since 2005, an analysis of data from 1993 through 2009 by economists at three universities has found no evidence to link the legalization of medical marijuana to increased use of the drug among high school students.
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** RADIOLOGY / NUCLEAR MEDICINE News **
Pancreatic Cancer Patients Benefit From Erlotinib Added To Bevacizumab/Chemoradiotherapy Regimen
http://mnt.to/a/46Nz
The addition of high doses of erlotinib to the treatment regimen of bevacizumab and capecitabine with radiotherapy seems to benefit patients with locally advanced pancreatic cancer, according to results of a phase I study presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
Human Pancreatic Tumor Growth In Hypoxic Xenografts Reduced By A Combination Of TH-302 And Radiation
http://mnt.to/a/46Nv
A combination of the prodrug TH-302 and radiation may provide an effective treatment strategy for pancreatic cancer, according to preclinical results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
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** RESPIRATORY / ASTHMA News **
Protection Against Respiratory Infection Linked To Asthma From Dog-Associated House Dust
http://mnt.to/a/46ND
House dust from homes with dogs appears to protect against infection with a common respiratory virus that is associated with the development of asthma in children. Researchers from the University of California, San Francisco, present their findings today at the 2012 General Meeting of the American Society for Microbiology.
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** SENIORS / AGING News **
Surprisingly High Untreated Kidney Failure Among Adults
http://mnt.to/a/46Ns
JAMA publishes an article today (20th June), showing a surprisingly high rate of untreated kidney failure amongst adults. The study involved nearly 2 million adults in Canada and the rate was considerably higher amongst older adults.
How The Key Enzyme Involved In Aging, Cancer Assembles
http://mnt.to/a/46MY
UCLA biochemists have mapped the structure of a key protein-RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging.The researchers found that a region at the end of the p65 protein that includes a flexible tail is responsible for bending telomerase's RNA backbone in order to create a scaffold for the assembly of other protein building blocks.
Caring For The Elderly Within UK Bangladeshi And Pakistani Communities
http://mnt.to/a/46MM
Over the next 20 years the proportion of older people living within the Bangladeshi and Pakistani communities in the UK will increase significantly. Most expect that their immediate family, particularly female family members, will provide the majority of care for them in their old age, according to new research funded by the Economic and Social Research Council (ESRC).
New Clinical Practice Guidelines On The Management Of Osteoporosis In Men
http://mnt.to/a/46MH
Osteoporosis in men causes significant morbidity and mortality. The Endocrine Society has released clinical practice guidelines (CPG) for management of this condition in men. "Osteoporosis in Men: An Endocrine Society Clinical Practice Guideline," is published in the June 2012 issue of the Journal of Clinical Endocrinology and Metabolism (JCEM), a publication of The Endocrine Society.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Sleep Regulation Influenced By Dopamine Levels
http://mnt.to/a/46PL
According to a study published in the journal PLoS Biology, dopamine, a neurotransmitter that helps controls the brain's reward and pleasure centers, also plays a role in sleep regulation.The study was conducted by researchers from CIBERNED (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas), dependant on the Spanish Ministry of Economy and Competitiveness through the Carlos III Health Institute, and from the Faculty of Biology of the University of Barcelona.
Dopamine And Sleep Regulation
http://mnt.to/a/46NB
A group of Spanish researchers has discovered a new function of the neurotransmitter dopamine in controlling sleep regulation. Dopamine acts in the pineal gland, which is central to dictating the 'circadian rhythm' in humans - the series of biological processes that enables brain activity to adapt to the time of the day (that is, light and dark cycles).
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** STEM CELL RESEARCH News **
Cancer Stem Cell Death In Pancreatic Cancer Cell Lines Caused By Metformin Treatment
http://mnt.to/a/46Nx
Results of some preclinical trials have shown that low doses of the antidiabetic drug metformin may effectively destroy cancer stem cells, a group of cells that are considered to be responsible for tumor initiation and, because they are resistant to standard chemotherapies, tumor relapse.
Opening The Door For Use Of Cardiac Stem Cell Patches In Disease Research, Testing Of New Drug Treatments, Therapies To Repair Damaged Heart Muscle
http://mnt.to/a/46Nb
A cutting-edge method developed at the University of Michigan Center for Arrhythmia Research successfully uses stem cells to create heart cells capable of mimicking the heart's crucial squeezing action.
New Combo Treatment Offers Hope For Pancreatic Cancer Patients
http://mnt.to/a/46N7
Combining a new targeted therapy with standard chemotherapy may help defeat pancreatic cancer, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, being held here June 18-21.
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** TRANSPLANTS / ORGAN DONATIONS News **
For Heart Transplant Patients Whose Arteries Reclose After Stenting, Survival Rates Are Lower
http://mnt.to/a/46MQ
Heart transplant patients are notorious for developing an aggressive form of coronary artery disease that can often result in heart failure, death or the need for repeat transplantation. The condition can also have a negative impact on future cardiac procedures, such as stenting.
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** TROPICAL DISEASES News **
Malaria's Spread May Be Encouraged By Rising Type 2 Diabetes Prevalence
http://mnt.to/a/46PC
The mosquito's immune system is suppressed by human insulin, which could be bad news for the spread of malaria if the number of people in Africa with diabetes type 2 continues to grow at its present rate, researchers from the University of California, Davis, explained in the journal Infection and Immunity.
What Is Leptospirosis? What Causes Leptospirosis?
http://mnt.to/a/46Pm
Leptospirosis is a fairly uncommon bacterial infection caused by a strain of Leptospira. It is most commonly transmitted from animals to humans when people with unhealed breaks in the skin, come into contact with water or soil that has been contaminated with animal urine - the bacterium can also enter the body through the eyes or mucous membranes.
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** UROLOGY / NEPHROLOGY News **
Chronic Kidney Disease And Heart Attack Risk
http://mnt.to/a/46PR
An article published Online First in The Lancet reveals that the risk of coronary heart disease in patients with chronic kidney disease is as high as that of patients who had a previous heart attack.
Surprisingly High Untreated Kidney Failure Among Adults
http://mnt.to/a/46Ns
JAMA publishes an article today (20th June), showing a surprisingly high rate of untreated kidney failure amongst adults. The study involved nearly 2 million adults in Canada and the rate was considerably higher amongst older adults.
Beating Urinary Tract Infections In Mouse Model
http://mnt.to/a/46MS
Scientists at Washington University School of Medicine in St. Louis have found new clues to why some urinary tract infections recur persistently after multiple rounds of treatment.Their research, conducted in mice, suggests that the bacteria that cause urinary tract infections take advantage of a cellular waste disposal system that normally helps fight invaders.
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** VETERINARY News **
Identification Of New Cerebellar Ataxia Gene In Dogs Offers Novel Candidate Gene In Human Early-Onset Degenerative Ataxias
http://mnt.to/a/46MN
Researchers at the University of Helsinki and the Folkhalsan Research Center, Finland, have identified the genetic cause of early-onset progressive cerebellar degeneration in the Finnish Hound dog breed.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Breast Cancer Screening Should Start At 40, Says American Medical Association
http://mnt.to/a/46PS
Women, when they reach 40 years of age, should be eligible for screening mammography, and should have that screening covered by insurance, says the American Medical Association (AMA), in what it describes as a recommendation update.
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