Tailoring Care for Patients with Atrial Fibrillation and CKD

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INDUSTRY HIGHLIGHT CARDIOLOGY About This Content
News and Information for Healthcare Professionals	June 18, 2012
Tailoring Care for Patients with Atrial Fibrillation and CKD Individuals with chronic kidney disease (CKD) are predisposed to experiencing cardiovascular events, with an especially high prevalence of atrial fibrillation (AF).1 In patients with end-stage renal disease, AF prevalence may be as high as 13% to 27%, markedly higher than the general population (up to 27%).2,3 Special attention may be required when managing AF in patients with CKD—as it represents a major cause of morbidity and mortality in this vulnerable population. The increased frequency of AF in CKD patients may be explained by multiple mechanisms. In these patients, atherosclerotic and structural heart disease—such as coronary artery disease, valvular disease, and left ventricular hypertrophy—have been correlated with AF.2 Other risk factors for AF in these patients include electrolyte disturbances associated with hemodialysis, sympathetic nervous system activation, and abnormalities in the renin-angiotensin system.2 Learn more about tailoring your care plan for patient with AF and CKD Read the full article at MedPageToday.com 1 Alonso A, et al. Chronic Kidney Disease is Associated With the Incidence of Atrial Fibrillation: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation. 2011;123:2946-2953. 2 Genovesi S, et al. Prevalence of Atrial Fibrillation and Associated Factors in a Population of Long-Term Hemodialysis Patients. Am J Kidney Dis. 2005;46:897-902. 3 US Renal Data System: USRDS 2005 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2005.

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