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** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **
Heroin And Morphine Addiction Blocker Breakthrough
http://mnt.to/a/47KY
New research has made a tremendous discovery proving that it is possible to block addiction to heroin and morphine, while increasing pain relief at the same time.According to the scientists, from the University of Adelaide and the University of Colorado, they have identified the key mechanism in the body's immune system that intensifies addiction to these potentially harmful drugs.
How The Risk Of ALS Is Affected By Smoking, Alcohol Consumption
http://mnt.to/a/47Jq
A population-based case-control study of the rare but devastating neurological disease amyotrophic lateral sclerosis (ALS) has shown that the risk of such disease is increased among smokers, as has been shown previously.
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** ALLERGY News **
Auvi-Q™, First Voice-Guided Epinephrine Auto-Injector For Patients With Life-Threatening Allergies, Receives FDA Approval
http://mnt.to/a/47Jf
Breakthrough device design talks patients and caregivers through the injection processSanofi (EURONEXT: SAN and NYSE: SNY) have announced that the U.S. Food and Drug Administration (FDA) has approved Auvi-Q (epinephrine injection, USP) for the emergency treatment of life-threatening allergic reactions in people who are at risk for or have a history of anaphylaxis.
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** ALZHEIMER'S / DEMENTIA News **
Regular Dietary Cocoa Flavanol Intake May Slow Memory Decline In Seniors
http://mnt.to/a/47K3
According to a new study published online in the journal Hypertension, researchers from the University of L'Aquila, Italy, have found convincing new evidence that cognitive function in elderly people with early memory decline can be improved by regular consumption of dietary cocoa flavanols.
Latrepirdine, Which Failed In US Clinical Trials Of Alzheimer's Disease, Shows New Potential In Animal Model
http://mnt.to/a/47Jm
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions.
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** BIOLOGY / BIOCHEMISTRY News **
Success Of Engineered Tissue Depends On Where It's Grown
http://mnt.to/a/47KF
Cells grown on different types of scaffolds vary in their ability to help repair damaged blood vesselsTissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases.
How Cancer Cells "Hijack" A Mechanism To Grow
http://mnt.to/a/47JX
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have discovered a mechanism that explains how some cancer cells "hijack" a biological process to potentially activate cell growth and the survival of cancer gene expression.
Artificial Retina Could Restore Sight To The Blind
http://mnt.to/a/47JR
Two researchers in the US have taken a huge step forward in developing technology to help blind people see: they have made an artificial retina that restored normal vision in blind mice. And they have already worked out a way to make a similar device for monkeys, which they hope to quickly redesign and test for human use.
Viable Stem Cells Suitable For Biomedical Research From Human Embryos Frozen For 18 Years
http://mnt.to/a/47Jn
Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research.
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** BLOOD / HEMATOLOGY News **
Heart Disease Risk May Be Influenced By Blood Type
http://mnt.to/a/47Kc
People with blood type A, B, or AB had a higher risk for coronary heart disease when compared to those with blood type O, according to new research published in Arteriosclerosis, Thrombosis and Vascular Biology, an American Heart Association journal.
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** CANCER / ONCOLOGY News **
Cause Of Burkitt Lymphoma Discovered
http://mnt.to/a/47L2
Burkitt lymphoma is an extremely fast growing form of non-Hodgkin's lymphoma that originates from a subgroup of white blood cells called B lymphocytes of the immune system. Now, researchers at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch have discovered a vital component that converts the immune cells into malignant lymphoma cells.
Internal Microscopic Diagnostic Devices - Clinicians Need More Training
http://mnt.to/a/47KV
To diagnose illness in areas of the body that are hard-to-reach, clinicians increasingly use tiny space age probes, which can see inside single living cells. A new study published in the journal Digestive Diseases and Sciences reveals that specialists who are beginning to use these devices may be interpreting what they see in different ways.
Skin Cancer Patients Should Be Screened Before Receiving Vemurafenib
http://mnt.to/a/47KT
According to a study conducted by Cancer Research UK, different genetic mutations powering skin cancer may have an impact on how patients respond to the drug vemurafenib, meaning that individuals suffering from melanoma skin cancer should be screened prior to treatment.
Improved Understanding Of TREX Could See New Treatments For Cancer, Motor Neuron Disease, Myotonic Dystrophy
http://mnt.to/a/47K9
Decoded process could hold the key to future treatments for a wide range of chronic health problems including Motor Neuron Disease, myotonic dystrophy and a wide range of cancers, University of Sheffield scientists have revealed.
Physical And Psychological Well-Being Improved By Exercise During And After Cancer
http://mnt.to/a/47K7
Exercise may improve quality of life for people with cancer, according to Cochrane researchers. In two separate Cochrane systematic reviews, the authors gathered together evidence showing that activities such as walking and cycling can benefit those who are undergoing or have completed treatment for cancer.
New Method Introduced To Closely Model Diseases Caused By Splicing Defects
http://mnt.to/a/47JZ
A team led by scientists at Cold Spring Harbor Laboratory (CSHL) has developed a new way of making animal models for a broad class of human genetic diseases - those with pathology caused by errors in the splicing of RNA messages copied from genes.
How Cancer Cells "Hijack" A Mechanism To Grow
http://mnt.to/a/47JX
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have discovered a mechanism that explains how some cancer cells "hijack" a biological process to potentially activate cell growth and the survival of cancer gene expression.
Personalized Clinical Trial For Cancer Therapies May Be Possible With New Method
http://mnt.to/a/47JB
A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy - and may offer a way to further refine personalized cancer treatments.The approach, developed by investigators at Vanderbilt-Ingram Cancer Center, shows that erlotinib - a targeted therapy that acts on a growth factor receptor mutated in some lung, brain and other cancers - doesn't simply kill tumor cells as was previously assumed.
Sensitivity To Potential Glioblastoma Treatment Affected By Modification Of Tumor Suppressor
http://mnt.to/a/47Jt
Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.Biologists and oncologists have long understood that a protein called the epidermal growth factor receptor or EGFR is altered in at least 50 percent of patients with glioblastoma.
Risk Of Bladder Cancer Increased For Over 15 Million Americans Taking Diabetes Drugs
http://mnt.to/a/47Jk
A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that patients taking thiazolidinedione (TZDs) drugs - which account for up to 20 percent of the drugs prescribed to diabetics in the United States - are two to three times more likely to develop bladder cancer than those who took a sulfonylurea drug, another common class of medications for diabetes.
Potential New Blood Test To Guide Treatment For Kidney Cancer
http://mnt.to/a/47J3
A common enzyme that is easily detected in blood may predict how well patients with advanced kidney cancer will respond to a specific treatment, according to doctors at Duke Cancer Institute.
Bowel Cancer Caused By Faulty Gene And High Iron Levels
http://mnt.to/a/47HM
New research published in Cell Reports has revealed that high levels of iron switches on a key pathway in people with faults in a critical anti-cancer gene (APC) that could raise the risk of bowel cancer.
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** CARDIOVASCULAR / CARDIOLOGY News **
Heart Attack Test Gives Diagnosis In 1 Hour
http://mnt.to/a/47K4
A more sensitive test for heart attack may cut the diagnosis time to one hour, removing the need for prolonged monitoring in 3 out of 4 patients who present to the Emergency Department (ED) with chest pains, according to a new US study published this week.
A Heart Disease Vaccine Becomes More Likely
http://mnt.to/a/47K2
It is no secret that heart disease is still the USA's No. 1 killer, but not many are aware that cholesterol is greatly assisted by the immune system's inflammatory cells in causing dangerous arterial plaque buildup that can trigger a heart attack.
Regular Exercise In Middle Age Protects Heart
http://mnt.to/a/47JC
Research on more than 4,000 middle-aged Britons finds that staying physically active into the senior years is linked to lower markers of inflammationwhich is important for protecting the heart.
For Atherosclerosis Risk, Egg Yolk Consumption Almost As Bad As Smoking
http://mnt.to/a/47Jy
Newly published research led by Dr. David Spence of Western University, Canada, shows that eating egg yolks accelerates atherosclerosis in a manner similar to smoking cigarettes. Surveying more than 1200 patients, Dr.
Multi-Center Study On Cardiac Amyloidosis
http://mnt.to/a/47Jp
Researchers at Boston University School of Medicine (BUSM) have been part of a multicenter observational study called TRACS (Transthyretin Amyloidosis Cardiac Study) to help determine the health significance of a particular gene mutation which is commonly found in Black Americans.
A Solution To The Riddle Of Congenital Heart Defects Provided By Supercomputers
http://mnt.to/a/47Jg
About 25,000 Danes currently live with congenital heart defects. Both heredity and environment play a role for these malformations, but exactly how various risk factors influence the development of the heart during pregnancy has been a mystery until now.
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** COLORECTAL CANCER News **
Bowel Cancer Caused By Faulty Gene And High Iron Levels
http://mnt.to/a/47HM
New research published in Cell Reports has revealed that high levels of iron switches on a key pathway in people with faults in a critical anti-cancer gene (APC) that could raise the risk of bowel cancer.
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** CONFERENCES News **
6th Annual World Drug Safety Congress Europe, 11-13 September 2012, London, UK
http://mnt.to/a/47KS
What will big changes in Europe's pharmacovigilance legislation landscape mean for the way pharma operates now and in the future? This question is one that seems to be constantly queried within the pharma industry recently, as professionals debate what significant challenges their organisations will face and how these can be overcome.
Novel Strategies To Improve Success In Cancer Vaccine Clinical Trials, 19 - 20 September 2012, London, UK
http://mnt.to/a/47KR
There have so far only been three cancer vaccines approved by the FDA, and many others are now nearing the end of their clinical trials. Two of these were vaccines for HPV, which is responsible for 70% of cervical cancer.
CBI's Forum On Sponsor / CRO System And Business Process Integration, 15-16 November 2012, New Jersey
http://mnt.to/a/47KQ
CBI, a subsidiary of Advanstar Communications, is pleased to announce the agenda for CBI's Forum on Sponsor/CRO System and Business Process Integration taking place November 15-16, 2012 at the Hilton in East Brunswick, New Jersey.
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** COSMETIC MEDICINE / PLASTIC SURGERY News **
How Anti-Aging Costmetics Work
http://mnt.to/a/47Jx
A team of investigators from UC Davis and Peking University have discovered a mechanism that may explain how alpha hydroxyl acids (AHAs) -- the key ingredient in cosmetic chemical peels and wrinkle-reducing creams - work to enhance skin appearance.
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** DENTISTRY News **
The Impact On Children, Families Of Poor Oral Health
http://mnt.to/a/47Js
Poor oral health, dental disease, and tooth pain can put kids at a serious disadvantage in school, according to a new Ostrow School of Dentistry of USC study."The Impact of Oral Health on the Academic Performance of Disadvantaged Children," appearing in the September 2012 issue of the American Journal of Public Health, examined nearly 1500 socioeconomically disadvantaged elementary and high school children in the Los Angeles Unified School District, matching their oral health status to their academic achievement and attendance records.
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** DERMATOLOGY News **
How Anti-Aging Costmetics Work
http://mnt.to/a/47Jx
A team of investigators from UC Davis and Peking University have discovered a mechanism that may explain how alpha hydroxyl acids (AHAs) -- the key ingredient in cosmetic chemical peels and wrinkle-reducing creams - work to enhance skin appearance.
----------------------------------------------
** DIABETES News **
Larger Babies Often Born To Overweight And Obese Women
http://mnt.to/a/47Kd
Among pregnant women who did not develop gestational diabetes, overweight women were 65 percent more likely, and obese women 163 percent more likely, to have overly large babies than their healthy weight counterparts.
Risk Of Bladder Cancer Increased For Over 15 Million Americans Taking Diabetes Drugs
http://mnt.to/a/47Jk
A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that patients taking thiazolidinedione (TZDs) drugs - which account for up to 20 percent of the drugs prescribed to diabetics in the United States - are two to three times more likely to develop bladder cancer than those who took a sulfonylurea drug, another common class of medications for diabetes.
----------------------------------------------
** EYE HEALTH / BLINDNESS News **
Effective Prosthetic Retinal Device For Blindness
http://mnt.to/a/47JS
The Proceedings of the National Academy of Sciences (PNAS) reports a major breakthrough by two Weill Cornell Medical College researchers in the longstanding efforts of restoring sight. The team managed to decipher the retina's neural code from a mouse and coupled this information to a novel prosthetic device to restore sight to blind mice.
Artificial Retina Could Restore Sight To The Blind
http://mnt.to/a/47JR
Two researchers in the US have taken a huge step forward in developing technology to help blind people see: they have made an artificial retina that restored normal vision in blind mice. And they have already worked out a way to make a similar device for monkeys, which they hope to quickly redesign and test for human use.
----------------------------------------------
** FLU / COLD / SARS News **
FDA Approves Flu Vaccines For Coming Season
http://mnt.to/a/47L3
The U.S. Food and Drug Administration approved the formula for the influenza vaccine for all six manufacturers equipped to produce and distribute the shots for the 2012-2013 season. Experts from the World Health Organization, the FDA, and the Centers for Disease Control and Prevention (CDC) closely study influenza virus samples and patterns of global disease in order to identify strains that are most likely to cause illness during the approaching flu season.
----------------------------------------------
** GASTROINTESTINAL / GASTROENTEROLOGY News **
Bowel Cancer Caused By Faulty Gene And High Iron Levels
http://mnt.to/a/47HM
New research published in Cell Reports has revealed that high levels of iron switches on a key pathway in people with faults in a critical anti-cancer gene (APC) that could raise the risk of bowel cancer.
----------------------------------------------
** GENETICS News **
Skin Cancer Patients Should Be Screened Before Receiving Vemurafenib
http://mnt.to/a/47KT
According to a study conducted by Cancer Research UK, different genetic mutations powering skin cancer may have an impact on how patients respond to the drug vemurafenib, meaning that individuals suffering from melanoma skin cancer should be screened prior to treatment.
Improved Understanding Of TREX Could See New Treatments For Cancer, Motor Neuron Disease, Myotonic Dystrophy
http://mnt.to/a/47K9
Decoded process could hold the key to future treatments for a wide range of chronic health problems including Motor Neuron Disease, myotonic dystrophy and a wide range of cancers, University of Sheffield scientists have revealed.
Studies Of Obsessive-Compulsive Disorder And Tourette Syndrome Published
http://mnt.to/a/47K6
Two papers that will appear in the journal Molecular Psychiatry, both receiving advance online release, may help identify gene variants that contribute to the risks of developing obsessive-compulsive disorder (OCD) or Tourette syndrome (TS).
New Method Introduced To Closely Model Diseases Caused By Splicing Defects
http://mnt.to/a/47JZ
A team led by scientists at Cold Spring Harbor Laboratory (CSHL) has developed a new way of making animal models for a broad class of human genetic diseases - those with pathology caused by errors in the splicing of RNA messages copied from genes.
How Cancer Cells "Hijack" A Mechanism To Grow
http://mnt.to/a/47JX
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have discovered a mechanism that explains how some cancer cells "hijack" a biological process to potentially activate cell growth and the survival of cancer gene expression.
Effective Prosthetic Retinal Device For Blindness
http://mnt.to/a/47JS
The Proceedings of the National Academy of Sciences (PNAS) reports a major breakthrough by two Weill Cornell Medical College researchers in the longstanding efforts of restoring sight. The team managed to decipher the retina's neural code from a mouse and coupled this information to a novel prosthetic device to restore sight to blind mice.
Scientists Develop Model For New Burkitt Lymphoma Treatments
http://mnt.to/a/47Jr
Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system.
Multi-Center Study On Cardiac Amyloidosis
http://mnt.to/a/47Jp
Researchers at Boston University School of Medicine (BUSM) have been part of a multicenter observational study called TRACS (Transthyretin Amyloidosis Cardiac Study) to help determine the health significance of a particular gene mutation which is commonly found in Black Americans.
New Treatment Options For High-Risk Childhood Leukemia Subtype Offered By Existing Drugs
http://mnt.to/a/47Jh
Discovery of the genetic basis of a high-risk subtype of leukemia shows some patients might benefit from existing targeted therapies, advancing the goal of curing all children with the most common childhood cancerScientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
A Solution To The Riddle Of Congenital Heart Defects Provided By Supercomputers
http://mnt.to/a/47Jg
About 25,000 Danes currently live with congenital heart defects. Both heredity and environment play a role for these malformations, but exactly how various risk factors influence the development of the heart during pregnancy has been a mystery until now.
Using Light To 'Tag And Track' Genetic Processes Much More Efficient
http://mnt.to/a/47Jd
In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging genetic material in some types of cells.
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** HEART DISEASE News **
Heart Disease Risk May Be Influenced By Blood Type
http://mnt.to/a/47Kc
People with blood type A, B, or AB had a higher risk for coronary heart disease when compared to those with blood type O, according to new research published in Arteriosclerosis, Thrombosis and Vascular Biology, an American Heart Association journal.
A Heart Disease Vaccine Becomes More Likely
http://mnt.to/a/47K2
It is no secret that heart disease is still the USA's No. 1 killer, but not many are aware that cholesterol is greatly assisted by the immune system's inflammatory cells in causing dangerous arterial plaque buildup that can trigger a heart attack.
For Atherosclerosis Risk, Egg Yolk Consumption Almost As Bad As Smoking
http://mnt.to/a/47Jy
Newly published research led by Dr. David Spence of Western University, Canada, shows that eating egg yolks accelerates atherosclerosis in a manner similar to smoking cigarettes. Surveying more than 1200 patients, Dr.
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** HIV / AIDS News **
A Heart Disease Vaccine Becomes More Likely
http://mnt.to/a/47K2
It is no secret that heart disease is still the USA's No. 1 killer, but not many are aware that cholesterol is greatly assisted by the immune system's inflammatory cells in causing dangerous arterial plaque buildup that can trigger a heart attack.
Using Light To 'Tag And Track' Genetic Processes Much More Efficient
http://mnt.to/a/47Jd
In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging genetic material in some types of cells.
----------------------------------------------
** HYPERTENSION News **
Hypertension May Be Improved By Cocoa Compounds
http://mnt.to/a/47K8
Compounds in cocoa may help to reduce blood pressure, according to a new systematic review in The Cochrane Library. The researchers reviewed evidence from short-term trials in which participants were given dark chocolate or cocoa powder daily and found that their blood pressure dropped slightly compared to a control group.
----------------------------------------------
** IMMUNE SYSTEM / VACCINES News **
FDA Approves Flu Vaccines For Coming Season
http://mnt.to/a/47L3
The U.S. Food and Drug Administration approved the formula for the influenza vaccine for all six manufacturers equipped to produce and distribute the shots for the 2012-2013 season. Experts from the World Health Organization, the FDA, and the Centers for Disease Control and Prevention (CDC) closely study influenza virus samples and patterns of global disease in order to identify strains that are most likely to cause illness during the approaching flu season.
----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Canada's Freshwaters Polluted With Potent Human Toxins
http://mnt.to/a/47JY
Nutrient pollution, one of the greatest threats to our freshwater resources, is responsible for the algal blooms that blanket our lakes and waterways in summer months. Large blooms of cyanobacteria ('blue green algae') can cause fish kills, increase the cost of drinking water treatment, devalue shoreline properties, and pose health risks to people, pets, and wildlife.
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** IT / INTERNET / E-MAIL News **
More Successful Weight Loss With Online Obesity Programs
http://mnt.to/a/47Kb
Computer and web-based weight management programmes may provide a cost effective way of addressing the growing problem of obesity, according to a team of seven researchers who undertook a Cochrane systematic review.
A Solution To The Riddle Of Congenital Heart Defects Provided By Supercomputers
http://mnt.to/a/47Jg
About 25,000 Danes currently live with congenital heart defects. Both heredity and environment play a role for these malformations, but exactly how various risk factors influence the development of the heart during pregnancy has been a mystery until now.
----------------------------------------------
** LIVER DISEASE / HEPATITIS News **
Canada's Freshwaters Polluted With Potent Human Toxins
http://mnt.to/a/47JY
Nutrient pollution, one of the greatest threats to our freshwater resources, is responsible for the algal blooms that blanket our lakes and waterways in summer months. Large blooms of cyanobacteria ('blue green algae') can cause fish kills, increase the cost of drinking water treatment, devalue shoreline properties, and pose health risks to people, pets, and wildlife.
----------------------------------------------
** LUNG CANCER News **
Personalized Clinical Trial For Cancer Therapies May Be Possible With New Method
http://mnt.to/a/47JB
A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy - and may offer a way to further refine personalized cancer treatments.The approach, developed by investigators at Vanderbilt-Ingram Cancer Center, shows that erlotinib - a targeted therapy that acts on a growth factor receptor mutated in some lung, brain and other cancers - doesn't simply kill tumor cells as was previously assumed.
----------------------------------------------
** LYMPHOMA / LEUKEMIA / MYELOMA News **
Cause Of Burkitt Lymphoma Discovered
http://mnt.to/a/47L2
Burkitt lymphoma is an extremely fast growing form of non-Hodgkin's lymphoma that originates from a subgroup of white blood cells called B lymphocytes of the immune system. Now, researchers at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch have discovered a vital component that converts the immune cells into malignant lymphoma cells.
Scientists Develop Model For New Burkitt Lymphoma Treatments
http://mnt.to/a/47Jr
Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system.
New Treatment Options For High-Risk Childhood Leukemia Subtype Offered By Existing Drugs
http://mnt.to/a/47Jh
Discovery of the genetic basis of a high-risk subtype of leukemia shows some patients might benefit from existing targeted therapies, advancing the goal of curing all children with the most common childhood cancerScientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
----------------------------------------------
** MEDICAL DEVICES / DIAGNOSTICS News **
Internal Microscopic Diagnostic Devices - Clinicians Need More Training
http://mnt.to/a/47KV
To diagnose illness in areas of the body that are hard-to-reach, clinicians increasingly use tiny space age probes, which can see inside single living cells. A new study published in the journal Digestive Diseases and Sciences reveals that specialists who are beginning to use these devices may be interpreting what they see in different ways.
Heart Attack Test Gives Diagnosis In 1 Hour
http://mnt.to/a/47K4
A more sensitive test for heart attack may cut the diagnosis time to one hour, removing the need for prolonged monitoring in 3 out of 4 patients who present to the Emergency Department (ED) with chest pains, according to a new US study published this week.
Effective Prosthetic Retinal Device For Blindness
http://mnt.to/a/47JS
The Proceedings of the National Academy of Sciences (PNAS) reports a major breakthrough by two Weill Cornell Medical College researchers in the longstanding efforts of restoring sight. The team managed to decipher the retina's neural code from a mouse and coupled this information to a novel prosthetic device to restore sight to blind mice.
Artificial Retina Could Restore Sight To The Blind
http://mnt.to/a/47JR
Two researchers in the US have taken a huge step forward in developing technology to help blind people see: they have made an artificial retina that restored normal vision in blind mice. And they have already worked out a way to make a similar device for monkeys, which they hope to quickly redesign and test for human use.
Using Light To 'Tag And Track' Genetic Processes Much More Efficient
http://mnt.to/a/47Jd
In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging genetic material in some types of cells.
----------------------------------------------
** MELANOMA / SKIN CANCER News **
Skin Cancer Patients Should Be Screened Before Receiving Vemurafenib
http://mnt.to/a/47KT
According to a study conducted by Cancer Research UK, different genetic mutations powering skin cancer may have an impact on how patients respond to the drug vemurafenib, meaning that individuals suffering from melanoma skin cancer should be screened prior to treatment.
----------------------------------------------
** MENTAL HEALTH News **
Libya Faces Mental Health Crisis
http://mnt.to/a/47JK
Libya is facing a mental health crisis with experts warning of a lack of qualified health professionals to deal with the problem. In the first-ever study of the effect of Libya's conflict on the mental health of its populations, researchers at The University of Queensland (UQ) have estimated the prevalence of post-traumatic stress disorder (PTSD) and depression in Libya since the country's 2011 civil conflict.
----------------------------------------------
** MUSCULAR DYSTROPHY / ALS News **
How The Risk Of ALS Is Affected By Smoking, Alcohol Consumption
http://mnt.to/a/47Jq
A population-based case-control study of the rare but devastating neurological disease amyotrophic lateral sclerosis (ALS) has shown that the risk of such disease is increased among smokers, as has been shown previously.
----------------------------------------------
** NEUROLOGY / NEUROSCIENCE News **
Improved Understanding Of TREX Could See New Treatments For Cancer, Motor Neuron Disease, Myotonic Dystrophy
http://mnt.to/a/47K9
Decoded process could hold the key to future treatments for a wide range of chronic health problems including Motor Neuron Disease, myotonic dystrophy and a wide range of cancers, University of Sheffield scientists have revealed.
New Method Introduced To Closely Model Diseases Caused By Splicing Defects
http://mnt.to/a/47JZ
A team led by scientists at Cold Spring Harbor Laboratory (CSHL) has developed a new way of making animal models for a broad class of human genetic diseases - those with pathology caused by errors in the splicing of RNA messages copied from genes.
Personalized Clinical Trial For Cancer Therapies May Be Possible With New Method
http://mnt.to/a/47JB
A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy - and may offer a way to further refine personalized cancer treatments.The approach, developed by investigators at Vanderbilt-Ingram Cancer Center, shows that erlotinib - a targeted therapy that acts on a growth factor receptor mutated in some lung, brain and other cancers - doesn't simply kill tumor cells as was previously assumed.
White Matter Development In The Postnatal Brain Impacted By External Stimulation
http://mnt.to/a/47Jw
A team at Children's National Medical Center has found that external stimulation has an impact on the postnatal development of a specific region of the brain. Published in Nature Neuroscience, the study used sensory deprivation to look at the growth and collection of NG2-expressing oligodendrocyte progenitor cells (NG2 cells) in the sensory cortex of the brain.
Sensitivity To Potential Glioblastoma Treatment Affected By Modification Of Tumor Suppressor
http://mnt.to/a/47Jt
Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.Biologists and oncologists have long understood that a protein called the epidermal growth factor receptor or EGFR is altered in at least 50 percent of patients with glioblastoma.
----------------------------------------------
** NUTRITION / DIET News **
Hypertension May Be Improved By Cocoa Compounds
http://mnt.to/a/47K8
Compounds in cocoa may help to reduce blood pressure, according to a new systematic review in The Cochrane Library. The researchers reviewed evidence from short-term trials in which participants were given dark chocolate or cocoa powder daily and found that their blood pressure dropped slightly compared to a control group.
Regular Dietary Cocoa Flavanol Intake May Slow Memory Decline In Seniors
http://mnt.to/a/47K3
According to a new study published online in the journal Hypertension, researchers from the University of L'Aquila, Italy, have found convincing new evidence that cognitive function in elderly people with early memory decline can be improved by regular consumption of dietary cocoa flavanols.
Appearance Matters More Than Health To Young Adults
http://mnt.to/a/47JW
When it comes to college-age individuals taking care of their bodies, appearance is more important than health, research conducted at the University of Missouri suggests. MarÃa Len-RÃos, an associate professor of strategic communication, Suzanne Burgoyne, a professor of theater, and a team of undergraduate researchers studied how college-age women view their bodies and how they feel about media messages aimed at women.
For Atherosclerosis Risk, Egg Yolk Consumption Almost As Bad As Smoking
http://mnt.to/a/47Jy
Newly published research led by Dr. David Spence of Western University, Canada, shows that eating egg yolks accelerates atherosclerosis in a manner similar to smoking cigarettes. Surveying more than 1200 patients, Dr.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
Evaluating Benefits And Risks Of Obesity Drugs
http://mnt.to/a/47KW
Obesity currently affects 1 in 3 adults. Now, The George Washington University School of Public Health and Health Services (GW) has released a report representing consensus findings from a cross-section of stakeholders that could help transform the methods used to assess interventions to treat obesity.
Larger Babies Often Born To Overweight And Obese Women
http://mnt.to/a/47Kd
Among pregnant women who did not develop gestational diabetes, overweight women were 65 percent more likely, and obese women 163 percent more likely, to have overly large babies than their healthy weight counterparts.
More Successful Weight Loss With Online Obesity Programs
http://mnt.to/a/47Kb
Computer and web-based weight management programmes may provide a cost effective way of addressing the growing problem of obesity, according to a team of seven researchers who undertook a Cochrane systematic review.
New Approaches For Evaluating Benefits And Risks Of Obesity Drugs Outlined By GWU Consensus Report
http://mnt.to/a/47K5
The George Washington University School of Public Health and Health Services (GW) has released a report representing consensus findings from a cross-section of stakeholders that could help transform the process used to evaluate interventions to treat obesity, a public health crisis that now affects one in three adults.
Appearance Matters More Than Health To Young Adults
http://mnt.to/a/47JW
When it comes to college-age individuals taking care of their bodies, appearance is more important than health, research conducted at the University of Missouri suggests. MarÃa Len-RÃos, an associate professor of strategic communication, Suzanne Burgoyne, a professor of theater, and a team of undergraduate researchers studied how college-age women view their bodies and how they feel about media messages aimed at women.
Expert Suggests That Doctors Treat Lack Of Exercise As A Medical Condition
http://mnt.to/a/47Jv
A sedentary lifestyle is a common cause of obesity (1), and excessive body weight and fat in turn are considered catalysts for diabetes (2), high blood pressure (3), joint damage (4) and other serious health problems.
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** OVARIAN CANCER News **
Mechanisms Of Acquired Chemoresistance In Ovarian Cancer Identified
http://mnt.to/a/47Fx
The presence of multiple ovarian cancer genomes in an individual patient and the absence or downregulation of the gene LRP1B are associated with the development of chemoresistance in women with the high-grade serous cancer subtype of ovarian cancer whose disease recurs after primary treatment.
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** PARKINSON'S DISEASE News **
Latrepirdine, Which Failed In US Clinical Trials Of Alzheimer's Disease, Shows New Potential In Animal Model
http://mnt.to/a/47Jm
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions.
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** PEDIATRICS / CHILDREN'S HEALTH News **
White Matter Development In The Postnatal Brain Impacted By External Stimulation
http://mnt.to/a/47Jw
A team at Children's National Medical Center has found that external stimulation has an impact on the postnatal development of a specific region of the brain. Published in Nature Neuroscience, the study used sensory deprivation to look at the growth and collection of NG2-expressing oligodendrocyte progenitor cells (NG2 cells) in the sensory cortex of the brain.
The Impact On Children, Families Of Poor Oral Health
http://mnt.to/a/47Js
Poor oral health, dental disease, and tooth pain can put kids at a serious disadvantage in school, according to a new Ostrow School of Dentistry of USC study."The Impact of Oral Health on the Academic Performance of Disadvantaged Children," appearing in the September 2012 issue of the American Journal of Public Health, examined nearly 1500 socioeconomically disadvantaged elementary and high school children in the Los Angeles Unified School District, matching their oral health status to their academic achievement and attendance records.
Scientists Develop Model For New Burkitt Lymphoma Treatments
http://mnt.to/a/47Jr
Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system.
New Treatment Options For High-Risk Childhood Leukemia Subtype Offered By Existing Drugs
http://mnt.to/a/47Jh
Discovery of the genetic basis of a high-risk subtype of leukemia shows some patients might benefit from existing targeted therapies, advancing the goal of curing all children with the most common childhood cancerScientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
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** PREGNANCY / OBSTETRICS News **
Larger Babies Often Born To Overweight And Obese Women
http://mnt.to/a/47Kd
Among pregnant women who did not develop gestational diabetes, overweight women were 65 percent more likely, and obese women 163 percent more likely, to have overly large babies than their healthy weight counterparts.
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** PSYCHOLOGY / PSYCHIATRY News **
Overconfidence Helps People Climb Social Ladder
http://mnt.to/a/47KZ
Overconfidence helps people climb the social ladder, increasing their social status and causing them to be promoted higher than their level of competence. Falsely believing oneself to be better than others has a strong effect on other people who tend to give displays of confidence more weight than they deserve.
Studies Of Obsessive-Compulsive Disorder And Tourette Syndrome Published
http://mnt.to/a/47K6
Two papers that will appear in the journal Molecular Psychiatry, both receiving advance online release, may help identify gene variants that contribute to the risks of developing obsessive-compulsive disorder (OCD) or Tourette syndrome (TS).
Regular Dietary Cocoa Flavanol Intake May Slow Memory Decline In Seniors
http://mnt.to/a/47K3
According to a new study published online in the journal Hypertension, researchers from the University of L'Aquila, Italy, have found convincing new evidence that cognitive function in elderly people with early memory decline can be improved by regular consumption of dietary cocoa flavanols.
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** PUBLIC HEALTH News **
The Impact On Children, Families Of Poor Oral Health
http://mnt.to/a/47Js
Poor oral health, dental disease, and tooth pain can put kids at a serious disadvantage in school, according to a new Ostrow School of Dentistry of USC study."The Impact of Oral Health on the Academic Performance of Disadvantaged Children," appearing in the September 2012 issue of the American Journal of Public Health, examined nearly 1500 socioeconomically disadvantaged elementary and high school children in the Los Angeles Unified School District, matching their oral health status to their academic achievement and attendance records.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
Auvi-Q™, First Voice-Guided Epinephrine Auto-Injector For Patients With Life-Threatening Allergies, Receives FDA Approval
http://mnt.to/a/47Jf
Breakthrough device design talks patients and caregivers through the injection processSanofi (EURONEXT: SAN and NYSE: SNY) have announced that the U.S. Food and Drug Administration (FDA) has approved Auvi-Q (epinephrine injection, USP) for the emergency treatment of life-threatening allergic reactions in people who are at risk for or have a history of anaphylaxis.
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** SCHIZOPHRENIA News **
New Drug Target For Schizophrenia Identified
http://mnt.to/a/47Jj
Researchers at Mount Sinai School of Medicine may have discovered why certain drugs to treat schizophrenia are ineffective in some patients. Published online in Nature Neuroscience, the research will pave the way for a new class of drugs to help treat this devastating mental illness, which impacts one percent of the world's population, 30 percent of whom do not respond to currently available treatments.
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** SENIORS / AGING News **
Regular Exercise In Middle Age Protects Heart
http://mnt.to/a/47JC
Research on more than 4,000 middle-aged Britons finds that staying physically active into the senior years is linked to lower markers of inflammationwhich is important for protecting the heart.
How Anti-Aging Costmetics Work
http://mnt.to/a/47Jx
A team of investigators from UC Davis and Peking University have discovered a mechanism that may explain how alpha hydroxyl acids (AHAs) -- the key ingredient in cosmetic chemical peels and wrinkle-reducing creams - work to enhance skin appearance.
Multi-Center Study On Cardiac Amyloidosis
http://mnt.to/a/47Jp
Researchers at Boston University School of Medicine (BUSM) have been part of a multicenter observational study called TRACS (Transthyretin Amyloidosis Cardiac Study) to help determine the health significance of a particular gene mutation which is commonly found in Black Americans.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Latrepirdine, Which Failed In US Clinical Trials Of Alzheimer's Disease, Shows New Potential In Animal Model
http://mnt.to/a/47Jm
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions.
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** SMOKING / QUIT SMOKING News **
How The Risk Of ALS Is Affected By Smoking, Alcohol Consumption
http://mnt.to/a/47Jq
A population-based case-control study of the rare but devastating neurological disease amyotrophic lateral sclerosis (ALS) has shown that the risk of such disease is increased among smokers, as has been shown previously.
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** SPORTS MEDICINE / FITNESS News **
Physical And Psychological Well-Being Improved By Exercise During And After Cancer
http://mnt.to/a/47K7
Exercise may improve quality of life for people with cancer, according to Cochrane researchers. In two separate Cochrane systematic reviews, the authors gathered together evidence showing that activities such as walking and cycling can benefit those who are undergoing or have completed treatment for cancer.
Regular Exercise In Middle Age Protects Heart
http://mnt.to/a/47JC
Research on more than 4,000 middle-aged Britons finds that staying physically active into the senior years is linked to lower markers of inflammationwhich is important for protecting the heart.
Expert Suggests That Doctors Treat Lack Of Exercise As A Medical Condition
http://mnt.to/a/47Jv
A sedentary lifestyle is a common cause of obesity (1), and excessive body weight and fat in turn are considered catalysts for diabetes (2), high blood pressure (3), joint damage (4) and other serious health problems.
----------------------------------------------
** STEM CELL RESEARCH News **
Success Of Engineered Tissue Depends On Where It's Grown
http://mnt.to/a/47KF
Cells grown on different types of scaffolds vary in their ability to help repair damaged blood vesselsTissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases.
Viable Stem Cells Suitable For Biomedical Research From Human Embryos Frozen For 18 Years
http://mnt.to/a/47Jn
Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research.
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** TROPICAL DISEASES News **
For Treatment Of Parasitic Infections, Antisense Approach Promising
http://mnt.to/a/47Jz
A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, it reduced the number of viable parasites by more than 90 percent, researchers from the University of Chicago Medicine report in the Proceedings of the National Academy of Sciences.
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** UROLOGY / NEPHROLOGY News **
Internal Microscopic Diagnostic Devices - Clinicians Need More Training
http://mnt.to/a/47KV
To diagnose illness in areas of the body that are hard-to-reach, clinicians increasingly use tiny space age probes, which can see inside single living cells. A new study published in the journal Digestive Diseases and Sciences reveals that specialists who are beginning to use these devices may be interpreting what they see in different ways.
Risk Of Bladder Cancer Increased For Over 15 Million Americans Taking Diabetes Drugs
http://mnt.to/a/47Jk
A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that patients taking thiazolidinedione (TZDs) drugs - which account for up to 20 percent of the drugs prescribed to diabetics in the United States - are two to three times more likely to develop bladder cancer than those who took a sulfonylurea drug, another common class of medications for diabetes.
Potential New Blood Test To Guide Treatment For Kidney Cancer
http://mnt.to/a/47J3
A common enzyme that is easily detected in blood may predict how well patients with advanced kidney cancer will respond to a specific treatment, according to doctors at Duke Cancer Institute.
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** WATER - AIR QUALITY / AGRICULTURE News **
Canada's Freshwaters Polluted With Potent Human Toxins
http://mnt.to/a/47JY
Nutrient pollution, one of the greatest threats to our freshwater resources, is responsible for the algal blooms that blanket our lakes and waterways in summer months. Large blooms of cyanobacteria ('blue green algae') can cause fish kills, increase the cost of drinking water treatment, devalue shoreline properties, and pose health risks to people, pets, and wildlife.
Victims Of Philippine Floods Offered Seeds Of Hope
http://mnt.to/a/47JV
Amidst horrendous flooding around Manila and major rice-growing across Luzon in the Philippines, some good news has emerged for rice farmers - Submarino rice - rice that can survive around 2 weeks of being under water.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Appearance Matters More Than Health To Young Adults
http://mnt.to/a/47JW
When it comes to college-age individuals taking care of their bodies, appearance is more important than health, research conducted at the University of Missouri suggests. MarÃa Len-RÃos, an associate professor of strategic communication, Suzanne Burgoyne, a professor of theater, and a team of undergraduate researchers studied how college-age women view their bodies and how they feel about media messages aimed at women.
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