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** ADHD News **
Elvanse® (Lisdexamfetamine Dimesylate) Receives UK Marketing Authorisation - New Option For The Treatment Of ADHD In Children And Adolescents
http://mnt.to/a/4bMt
Shire plc (LSE: SHP, NASDAQ: SHPG) have announced that its single-daily dose long-acting prodrug stimulant, Elvanse, has been authorised by the MHRA for the treatment of ADHD in children aged 6 years and over when response to previous methylphenidate treatment is considered clinically inadequate.
Substance Abuse Rates Higher In Teenagers With ADHD: Large Study
http://mnt.to/a/4bKB
A new study published online in the Journal of the American Academy of Child and Adolescent Psychiatry revealed a significantly higher prevalence of substance abuse and cigarette use by adolescents with attention deficit hyperactivity disorder (ADHD) histories than in those without ADHD.
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** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **
Recovering From Severe Addiction Is Possible - New Book
http://mnt.to/a/4bLr
A former drug addicted alcoholic and rehabilitation champion urges people to never give up hope that an addict can recover, no matter how far down the track to destruction they are. Ian Young was a drug addicted alcoholic who considered himself to be one step ahead of the law at all times.
Substance Abuse Rates Higher In Teenagers With ADHD: Large Study
http://mnt.to/a/4bKB
A new study published online in the Journal of the American Academy of Child and Adolescent Psychiatry revealed a significantly higher prevalence of substance abuse and cigarette use by adolescents with attention deficit hyperactivity disorder (ADHD) histories than in those without ADHD.
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** ALZHEIMER'S / DEMENTIA News **
Vascular Brain Injury Greater Risk Factor Than Amyloid Plaques In Cognitive Aging
http://mnt.to/a/4bMp
Vascular brain injury from conditions such as high blood pressure and stroke are greater risk factors for cognitive impairment among non-demented older people than is the deposition of the amyloid plaques in the brain that long have been implicated in conditions such as Alzheimer's disease, a study by researchers at the Alzheimer's Disease Research Center at UC Davis has found.
Caught In The Act - Protein 'Filmed' While Unfolding At Atomic Resolution
http://mnt.to/a/4bKG
By combining low temperatures and NMR spectroscopy, the scientists visualized seven intermediate forms of the CylR2 protein while cooling it down from 25°C to -16°C. Their results show that the most instable intermediate form plays a key role in protein folding.
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** ANXIETY / STRESS News **
High Level Of Attachment Anxiety May Lower Immunity, Increase Vulnerability To Illness
http://mnt.to/a/4bKt
Concerns and anxieties about one's close relationships appear to function as a chronic stressor that can compromise immunity, according to new research. In the study, researchers asked married couples to complete questionnaires about their relationships and collected saliva and blood samples to test participants' levels of a key stress-related hormone and numbers of certain immune cells.
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** AUTISM News **
Folic Acid Might Lower Autism Risk
http://mnt.to/a/4bLF
Women who take folic acid supplements four weeks before becoming pregnant and also during the first weeks of pregnancy have a lower risk of giving birth to children who eventually become diagnosed with an autism spectrum disorder (ASD), Norwegian researchers have reported in JAMA.
Genes For Autism And Schizophrenia Only Active In Developing Brains
http://mnt.to/a/4bJX
Genes linked to autism and schizophrenia are only switched on during the early stages of brain development, according to a study in mice led by researchers at the University of Oxford.This new study adds to the evidence that autism and schizophrenia are neurodevelopmental disorders, a term describing conditions that originate during early brain development.
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** BIOLOGY / BIOCHEMISTRY News **
Cell Circuits Remember Their History - MIT Engineers Design New Synthetic Biology Circuits That Combine Memory And Logic.
http://mnt.to/a/4bLs
MIT engineers have created genetic circuits in bacterial cells that not only perform logic functions, but also remember the results, which are encoded in the cell's DNA and passed on for dozens of generations.
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** BLOOD / HEMATOLOGY News **
Patient Safety Improved By Comprehensive Maternal Hemorrhage Protocols
http://mnt.to/a/4bK7
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest comprehensive maternal hemorrhage protocols reduce utilization of blood products and improve patient safety.
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** CANCER / ONCOLOGY News **
Surveillance May Be Best For Small Kidney Tumors
http://mnt.to/a/4bMP
Surveillance, or the watch and wait approach, may be the best option for older patients with small kidney tumors.The finding came from a large retrospective study which showed that surveillance is a safe alternative to surgery.
NICE Issues Preliminary Guidance To Not Recommend Jakavi™ In The Treatment Of Rare Blood Cancer As Not Cost-Effective
http://mnt.to/a/4bMw
Novartis today expressed disappointment at the National Institute for Health and Clinical Excellence's (NICE) preliminary recommendation to not recommend Jakavi™ (INC424, ruxolitinib) for the treatment of disease-related splenomegaly (enlarged spleen) or symptoms in adult patients with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post-polycythaemia vera myelofibrosis or post-essential thrombocythaemia myelofibrosis[i].
Borealis-2 Clinical Trial Evaluating OGX-427 In Combination With Second-Line Therapy For Bladder Cancer Announced
http://mnt.to/a/4bMr
OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) has announced plans for the initiation of the Borealis-2 clinical trial, an investigator-sponsored, randomized, controlled Phase 2 study evaluating OGX-427 in patients with advanced or metastatic bladder cancer who have disease progression following initial platinum-based chemotherapy treatment.
2013 Genitourinary Cancers Symposium: New Insights Into High-Risk Prostate Cancer; Management Of Small Kidney Tumors
http://mnt.to/a/4bLY
Research on promising new therapies and data on the relative benefits of established treatments for genitourinary cancers were released, in advance of the fourth annual Genitourinary Cancers Symposium, being held February 14-16, 2013, at the Rosen Shingle Creek in Orlando, FL.
Factors For Eradicating Gastric Cancer Causing Bacterium H Pylori
http://mnt.to/a/4bLJ
The bacterium Helicobacter pylori is one of the leading causes of gastric cancer worldwide, researchers analyzed the results of interventions that tried to eradicate the bacterium in several different Latin American population groups.
The Therapeutic Effect Of RNAi Gene Silencing In Cancer Treatment
http://mnt.to/a/4bKH
The new study published in Cancer Discovery, the flagship journal of the American Association of Cancer Research (AACR), involving three Spanish and six American research centres, presents significant results in treating cancer patients with nanoparticles containing ribonucleic acid interference (RNAi) molecules.
Improved Understanding Of Clear Cell Sarcoma Offered By Mouse Model
http://mnt.to/a/4bK2
Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises.
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** CARDIOVASCULAR / CARDIOLOGY News **
Risk Of Cardiovascular Death Doubled In Women With High Calcium Intake - High Risk Only In Those Taking Supplements
http://mnt.to/a/4bLw
High intakes of calcium (corresponding to diet and supplements) in women are associated with a higher risk of death from all causes, but cardiovascular disease in particular, compared with women with lower calcium intake, a study published today on bmj.
Acute Heart Failure Phase III Clinical Trial Designed To Assess Early Treatment On Cardiovascular Mortality And Symptoms Initiated
http://mnt.to/a/4bLq
Cardiorentis has initiated the first-ever acute heart failure (AHF) Phase III trial to be specifically designed to assess the effect of early treatment on cardiovascular mortality. TRUE-AHF (TRial of Ularitide's Efficacy and safety in patients with Acute Heart Failure) aims to show that early treatment with intravenous (IV) ularitide may reduce AHF symptoms in the short-term and cardiovascular mortality in the long-term.
During Pregnancy, Obstructive Sleep Apnea And Cardiac Symptoms Have 31 Percent Incidence Of Cardiac Dysfunction
http://mnt.to/a/4bKc
In a study to be presented on February 15 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that women with obstructive sleep apnea (OSA) and cardiac symptoms have a 31 percent incidence of cardiac dysfunction.
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** CLINICAL TRIALS / DRUG TRIALS News **
Borealis-2 Clinical Trial Evaluating OGX-427 In Combination With Second-Line Therapy For Bladder Cancer Announced
http://mnt.to/a/4bMr
OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) has announced plans for the initiation of the Borealis-2 clinical trial, an investigator-sponsored, randomized, controlled Phase 2 study evaluating OGX-427 in patients with advanced or metastatic bladder cancer who have disease progression following initial platinum-based chemotherapy treatment.
Acute Heart Failure Phase III Clinical Trial Designed To Assess Early Treatment On Cardiovascular Mortality And Symptoms Initiated
http://mnt.to/a/4bLq
Cardiorentis has initiated the first-ever acute heart failure (AHF) Phase III trial to be specifically designed to assess the effect of early treatment on cardiovascular mortality. TRUE-AHF (TRial of Ularitide's Efficacy and safety in patients with Acute Heart Failure) aims to show that early treatment with intravenous (IV) ularitide may reduce AHF symptoms in the short-term and cardiovascular mortality in the long-term.
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** CONFERENCES News **
3rd CMO Quality Oversight And Risk Management Conference, 16-17 April 2013, Boston, MA
http://mnt.to/a/4bMC
"This conference exceeded expectations due to interaction and conversation between presenters and attendees." - QA Manager, Kadmon PharmaceuticalsThat's how past participants at the CMO Quality Oversight & Risk Management Conference feel about the speakers and content at this annual Boston, MA conference.
Pregnant Mothers Benefit From Preemptive Treatment Of Severe Morning Sickness
http://mnt.to/a/4bL9
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing the effectiveness of preemptive treatment for hyperemesis gravidarum and severe morning sickness.
Live Surgery Ethics: The Safety Of The Patient Is The Prime Consideration
http://mnt.to/a/4bKF
During the final day of the 28th Annual EAU Congress, which will take place on 15-19 March 2013 in Milan, the European Association of Urology will release its official policy statement on live surgery ethics.
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** DEPRESSION News **
Depressive Symptoms In Young Adults May Be Reduced Through Interaction With Avatars
http://mnt.to/a/4bKC
Young adults, in a period of transition, are often reluctant to seek treatment for mental health problems because of the stigma, inadequate insurance coverage and difficulty finding a mental health care provider.
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** DERMATOLOGY News **
Shorter, Newer Antibiotic Regimen Shows Equal Effectiveness For Skin Infections
http://mnt.to/a/4bLG
Once daily treatment with a new antibiotic called tedizolid phosphate for six days proves just as successful as the antibiotic linezolid twice a day for ten 10 days, for patients with acute bacterial skin and skin structure infections.
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** DIABETES News **
Firstborns Have Higher Risk Of Diabetes, High Blood Pressure
http://mnt.to/a/4bM4
A new study from New Zealand finds firstborn children have reduced insulin effectiveness, a known risk factor for diabetes, and higher blood pressure, compared to children who have older siblings.
In Gulf Region More Than One-Third Are Obese And One-Quarter Have Diabetes
http://mnt.to/a/4bLS
With one of the highest rates of obesity in the world, the Gulf region is facing an epidemic of cardiovascular disease. At least 50% of the population is below the age of 25 and the high prevalence of risk factors signals a massive wave of cardiovascular disease in 10-15 years.
Community Health Workers Improve Diabetes Outcomes And Related Behaviors
http://mnt.to/a/4bKy
Researchers who conducted a clinical trial in American Samoa to test whether community health workers could help adults with type 2 diabetes found that the patients who received the intervention were twice as likely to make a clinically meaningful improvement as those who remained with care only in the clinic.
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** ENDOCRINOLOGY News **
Progesterone Shots Not Found To Reduce Preterm Delivery In Twin Pregnancies
http://mnt.to/a/4bKp
In a study to be presented on February 14 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's 33rd annual meeting, The Pregnancy Meeting ™, researchers will report findings that suggest that 17P, a form of progesterone, is not effective in preventing preterm birth among women with twin pregnancies - and may possibly be harmful.
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** FERTILITY News **
Rethink Of How Ovaries Develop
http://mnt.to/a/4bKJ
New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility.The study, now published in the journal PLOS ONE, also names a new type of cell that plays a key role in the development of ovaries and ovarian follicles, which are responsible for the production of eggs in women.
Frozen Embryo Replacement (FER) Has Better Outcomes Compared To Fresh In Vitro Fertilization (IVF)
http://mnt.to/a/4bKg
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Francisco, California, researchers will present findings showing perinatal outcomes of frozen/thawed embryo replacement (FER) have better outcomes compared to fresh in vitro fertilization (IVF), but worse outcomes compared to the non-IVF general population.
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** FLU / COLD / SARS News **
Vitamin C Helps Marathon Runners Reduce Risk Of Catching A Cold
http://mnt.to/a/4bMQ
An updated review of placebo-controlled trials on Vitamin C and the common cold finds the vitamin may help people under heavy physical stress, such as marathon runners and skiers, to reduce their risk of catching a cold.
SARS-Like Virus Can Probably Transmit Between People, UK
http://mnt.to/a/4bMN
The Health Protection Agency, UK, believes it has compelling evidence that a new SARS-like coronavirus can spread from human-to-human.A newly confirmed case of a person with coronavirus infection indicates that it occurred as a result of person-to-person transmission - the patient has no history of recent travel anywhere and no short- or long-term history of travel to the Middle East, the Health Protection Agency (HPA) announced today.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Pregnant Mothers Benefit From Preemptive Treatment Of Severe Morning Sickness
http://mnt.to/a/4bL9
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing the effectiveness of preemptive treatment for hyperemesis gravidarum and severe morning sickness.
Cesarean Section And Breastfeeding Practices Influence Infant Gut Microbiota, May Affect Health In Later Life
http://mnt.to/a/4bK5
Method of birth (vaginal birth s. cesarean delivery) and feeding practices (breastfeeding v. formula-feeding) influence the development of gut bacteria in newborns and thus may affect lifelong health, according to a new study in CMAJ (Canadian Medical Association Journal).
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** GENETICS News **
The Therapeutic Effect Of RNAi Gene Silencing In Cancer Treatment
http://mnt.to/a/4bKH
The new study published in Cancer Discovery, the flagship journal of the American Association of Cancer Research (AACR), involving three Spanish and six American research centres, presents significant results in treating cancer patients with nanoparticles containing ribonucleic acid interference (RNAi) molecules.
Caught In The Act - Protein 'Filmed' While Unfolding At Atomic Resolution
http://mnt.to/a/4bKG
By combining low temperatures and NMR spectroscopy, the scientists visualized seven intermediate forms of the CylR2 protein while cooling it down from 25°C to -16°C. Their results show that the most instable intermediate form plays a key role in protein folding.
New Strategy Identified For Interfering With A Potent Cancer-Causing Gene
http://mnt.to/a/4bKs
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible for this cancer in order to generate potential new therapeutics.
Improved Understanding Of Clear Cell Sarcoma Offered By Mouse Model
http://mnt.to/a/4bK2
Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises.
Genetic Root To Early-Onset Prostate Cancer Identified
http://mnt.to/a/4bJZ
Prostate cancer is often considered an elderly man's disease, and little is known about the approximately 2% of cases that arise in men who are aged 50 years or younger. Research published in Cell Press journal Cancer Cell uncovers the genetic origin of such early-onset prostate cancer.
Genes For Autism And Schizophrenia Only Active In Developing Brains
http://mnt.to/a/4bJX
Genes linked to autism and schizophrenia are only switched on during the early stages of brain development, according to a study in mice led by researchers at the University of Oxford.This new study adds to the evidence that autism and schizophrenia are neurodevelopmental disorders, a term describing conditions that originate during early brain development.
Inflammatory Gene Expression Changes Are Consistent In Humans, No Matter The Injury, But Not Reflected In Mouse Models
http://mnt.to/a/4bJW
Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition.
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** HEART DISEASE News **
In Gulf Region More Than One-Third Are Obese And One-Quarter Have Diabetes
http://mnt.to/a/4bLS
With one of the highest rates of obesity in the world, the Gulf region is facing an epidemic of cardiovascular disease. At least 50% of the population is below the age of 25 and the high prevalence of risk factors signals a massive wave of cardiovascular disease in 10-15 years.
Pregnant Women With High Blood Pressure At Increased Risk For Later Heart Disease
http://mnt.to/a/4bJT
High blood pressure during pregnancy - even once or twice during routine medical care - can signal substantially higher risks of heart and kidney disease and diabetes, according to new research in the American Heart Association journal Circulation.
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** HYPERTENSION News **
Firstborns Have Higher Risk Of Diabetes, High Blood Pressure
http://mnt.to/a/4bM4
A new study from New Zealand finds firstborn children have reduced insulin effectiveness, a known risk factor for diabetes, and higher blood pressure, compared to children who have older siblings.
Life-Saving Reduction In Sodium Consumption
http://mnt.to/a/4bJV
Less sodium in the U.S. diet could save 280,000 to 500,000 lives over 10 years, according to new research in the American Heart Association journal Hypertension.Using computer simulations and models researchers projected the effects of small (about 5 percent of a teaspoon of salt per person per day), steady annual reductions of sodium consumption in the U.
Pregnant Women With High Blood Pressure At Increased Risk For Later Heart Disease
http://mnt.to/a/4bJT
High blood pressure during pregnancy - even once or twice during routine medical care - can signal substantially higher risks of heart and kidney disease and diabetes, according to new research in the American Heart Association journal Circulation.
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** IMMUNE SYSTEM / VACCINES News **
High Level Of Attachment Anxiety May Lower Immunity, Increase Vulnerability To Illness
http://mnt.to/a/4bKt
Concerns and anxieties about one's close relationships appear to function as a chronic stressor that can compromise immunity, according to new research. In the study, researchers asked married couples to complete questionnaires about their relationships and collected saliva and blood samples to test participants' levels of a key stress-related hormone and numbers of certain immune cells.
Inflammatory Gene Expression Changes Are Consistent In Humans, No Matter The Injury, But Not Reflected In Mouse Models
http://mnt.to/a/4bJW
Existing mouse models do not appear to accurately reproduce the human genomic response to serious traumatic injury, including major burns, according to an article appearing in PNAS Early Edition.
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** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Vitamin C Helps Marathon Runners Reduce Risk Of Catching A Cold
http://mnt.to/a/4bMQ
An updated review of placebo-controlled trials on Vitamin C and the common cold finds the vitamin may help people under heavy physical stress, such as marathon runners and skiers, to reduce their risk of catching a cold.
SARS-Like Virus Can Probably Transmit Between People, UK
http://mnt.to/a/4bMN
The Health Protection Agency, UK, believes it has compelling evidence that a new SARS-like coronavirus can spread from human-to-human.A newly confirmed case of a person with coronavirus infection indicates that it occurred as a result of person-to-person transmission - the patient has no history of recent travel anywhere and no short- or long-term history of travel to the Middle East, the Health Protection Agency (HPA) announced today.
Study Reveals Effects Of Meningitis And Septicaemia On Learning In School Children
http://mnt.to/a/4bMv
A Meningitis Research Foundation funded study has shown that meningitis and septicaemia have a significant impact on children's school performance. Their ability to learn and their behaviour are especially affected and are worse than for children treated in intensive care with other critical illnesses.
Discovery Of Novel Targets And Targeting Compounds For Fighting Deadly Infectious Diseases Including MtB
http://mnt.to/a/4bMq
An international team of researchers from India, Brazil, Mexico, the USA, and Denmark led by Debmalya Barh from the Institute of Integrative Omics and Applied Biotechnology (IIOAB) in Nonakuri, Tamluk, Purba Medinipur, West Bengal, India have claimed to have identified a novel drug target (Acetate kinase) common to pathogens causing hemorrhagic diarrohea; tuberculosis, plague diphtheria, and Caseous lymphadenitis and two novel targets (Undecaprenyl pyrophosphate phosphatase enzyme and Outer membrane protein ompU) that may help to develop both a drug and a vaccine against almost all pathogenic Vibrio spp including Vibrio cholerae.
Factors For Eradicating Gastric Cancer Causing Bacterium H Pylori
http://mnt.to/a/4bLJ
The bacterium Helicobacter pylori is one of the leading causes of gastric cancer worldwide, researchers analyzed the results of interventions that tried to eradicate the bacterium in several different Latin American population groups.
Shorter, Newer Antibiotic Regimen Shows Equal Effectiveness For Skin Infections
http://mnt.to/a/4bLG
Once daily treatment with a new antibiotic called tedizolid phosphate for six days proves just as successful as the antibiotic linezolid twice a day for ten 10 days, for patients with acute bacterial skin and skin structure infections.
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** IT / INTERNET / E-MAIL News **
Simulations Show How Blood Vessels Regroup After Stroke
http://mnt.to/a/4bKx
By thinking of cells as programmable robots, researchers at Rice University hope to someday direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease.
Computer Simulations Set To Save Health Care
http://mnt.to/a/4bKv
New research from Indiana University has found that machine learning -- the same computer science discipline that helped create voice recognition systems, self-driving cars and credit card fraud detection systems -- can drastically improve both the cost and quality of health care in the United States.
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** LYMPHOMA / LEUKEMIA / MYELOMA News **
New Strategy Identified For Interfering With A Potent Cancer-Causing Gene
http://mnt.to/a/4bKs
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible for this cancer in order to generate potential new therapeutics.
Improved Treatment Alternative For Lymphoid Leukemia Suggested By International Study
http://mnt.to/a/4bJY
Discovering what they call the "Achilles' heel" for lymphoid leukemia, an international research team has tested a possible alternative treatment that eradicated the disease in mouse models.Reporting their results in the journal Cancer Cell, the scientists said the targeted molecular therapy described in their study could have direct implications for current treatment of Acute Lymphoid Leukemia (ALL) in people.
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** MEDICAL DEVICES / DIAGNOSTICS News **
Patients At Risk From Inaccurate Antibiotic Test Kits, Warns BMJ Investigation
http://mnt.to/a/4bLx
One of the world's leading producers of diagnostic tests has been falsely marketing one of their products, an investigation by the BMJ shows.Oxoid, owned by US diagnostics giant Thermofisher, has been selling antimicrobial susceptibility test (AST) discs that do not always contain the advertised amount of antibiotic.
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** MEDICARE / MEDICAID / SCHIP News **
Hospital Readmission And Death Rates Not Strongly Linked
http://mnt.to/a/4bMK
A study of over 3 million hospital admissions reveals that there is no significant association between hospital readmission and mortality rates among Medicare patients who suffer from heart attack, heart failure or pneumonia.
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** MEN'S HEALTH News **
Genetic Predisposition To Brain Injury After Preterm Birth May Be Sex-Specific
http://mnt.to/a/4bKk
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report that variation in a gene involved in inflammation is associated with developmental problems after preterm birth in females, but not males.
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** MENTAL HEALTH News **
Depressive Symptoms In Young Adults May Be Reduced Through Interaction With Avatars
http://mnt.to/a/4bKC
Young adults, in a period of transition, are often reluctant to seek treatment for mental health problems because of the stigma, inadequate insurance coverage and difficulty finding a mental health care provider.
----------------------------------------------
** MRSA / DRUG RESISTANCE News **
Shorter, Newer Antibiotic Regimen Shows Equal Effectiveness For Skin Infections
http://mnt.to/a/4bLG
Once daily treatment with a new antibiotic called tedizolid phosphate for six days proves just as successful as the antibiotic linezolid twice a day for ten 10 days, for patients with acute bacterial skin and skin structure infections.
Environmental Engineers Seek Strategy To Control Antibiotic Resistant Genes
http://mnt.to/a/4bKK
Rice University researchers "cured" a strain of bacteria of its ability to resist an antibiotic in an experiment that has implications for a long-standing public health crisis.Rice environmental engineer Pedro Alvarez and his team managed to remove the ability of the Pseudomonas aeruginosa microorganism to resist the antibiotic medication tetracycline by limiting its access to food and oxygen.
Global Human Health May Be Affected By Unchecked Antibiotic Use In Animals
http://mnt.to/a/4bKq
The increasing production and use of antibiotics, about half of which are used in animal production, is mirrored by the growing number of antibiotic resistance genes, or ARGs, effectively reducing antibiotics' ability to fend off diseases - in animals and humans.
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** NEUROLOGY / NEUROSCIENCE News **
Music Lessons Early In Life Increase Brain Development
http://mnt.to/a/4bML
Playing the recorder in kindergarten, piano lessons in first grade, clapping to the rhythm throughout elementary school music class, all of these can contribute to developing the brain.The new findings, published in the Journal of Neuroscience, reveal that musical training earlier than the age of seven has a significant impact on the development of the brain.
Vascular Brain Injury Greater Risk Factor Than Amyloid Plaques In Cognitive Aging
http://mnt.to/a/4bMp
Vascular brain injury from conditions such as high blood pressure and stroke are greater risk factors for cognitive impairment among non-demented older people than is the deposition of the amyloid plaques in the brain that long have been implicated in conditions such as Alzheimer's disease, a study by researchers at the Alzheimer's Disease Research Center at UC Davis has found.
Genetic Predisposition To Brain Injury After Preterm Birth May Be Sex-Specific
http://mnt.to/a/4bKk
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report that variation in a gene involved in inflammation is associated with developmental problems after preterm birth in females, but not males.
The Effects Of Maternal Obesity On Fetal Gene Expression And Neurodevelopment
http://mnt.to/a/4bKd
In a study to be presented on February 15 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers from Tufts Medical Center will present findings showing the effects of maternal obesity on a fetus, specifically in the development of the brain.
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** NURSING / MIDWIFERY News **
Community Health Workers Improve Diabetes Outcomes And Related Behaviors
http://mnt.to/a/4bKy
Researchers who conducted a clinical trial in American Samoa to test whether community health workers could help adults with type 2 diabetes found that the patients who received the intervention were twice as likely to make a clinically meaningful improvement as those who remained with care only in the clinic.
----------------------------------------------
** NUTRITION / DIET News **
Vitamin C Helps Marathon Runners Reduce Risk Of Catching A Cold
http://mnt.to/a/4bMQ
An updated review of placebo-controlled trials on Vitamin C and the common cold finds the vitamin may help people under heavy physical stress, such as marathon runners and skiers, to reduce their risk of catching a cold.
Limit Added Sugars In Beverages - Consumer Group Urges
http://mnt.to/a/4bMM
High levels of sugar or corn syrup in sodas are a major cause of obesity, diabetes, and other health problems, according to the Center for Science in the Public Interest (CSPI). As part of a strategy to reduce the American population's incredibly high sugar intake, the group, along with many other health-advocacy organizations, are proposing that the FDA strongly considers setting a safe limit on the level of sugar allowed in beverages.
Vitamin D Supplement Potency Often Not What Label Says
http://mnt.to/a/4bLH
When you buy your vitamin D supplements over-the-counter be careful, they may be less potent than the labels claim, researchers from Kaiser Permanente reported in JAMA Internal Medicine.Vitamin C insufficiency can be harmful to health, hence supplementation is commonly prescribed.
Risk Of Cardiovascular Death Doubled In Women With High Calcium Intake - High Risk Only In Those Taking Supplements
http://mnt.to/a/4bLw
High intakes of calcium (corresponding to diet and supplements) in women are associated with a higher risk of death from all causes, but cardiovascular disease in particular, compared with women with lower calcium intake, a study published today on bmj.
5 Of Chocolate's Sweet Benefits Highlighted In New American Chemical Society Video
http://mnt.to/a/4bKw
Just in time for Valentine's Day, the American Chemical Society (ACS), the world's largest scientific society, has released a new Bytesize Science video featuring five chemistry facts that highlight why chocolate, in moderation, may be good for you.
Life-Saving Reduction In Sodium Consumption
http://mnt.to/a/4bJV
Less sodium in the U.S. diet could save 280,000 to 500,000 lives over 10 years, according to new research in the American Heart Association journal Hypertension.Using computer simulations and models researchers projected the effects of small (about 5 percent of a teaspoon of salt per person per day), steady annual reductions of sodium consumption in the U.
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** OBESITY / WEIGHT LOSS / FITNESS News **
Limit Added Sugars In Beverages - Consumer Group Urges
http://mnt.to/a/4bMM
High levels of sugar or corn syrup in sodas are a major cause of obesity, diabetes, and other health problems, according to the Center for Science in the Public Interest (CSPI). As part of a strategy to reduce the American population's incredibly high sugar intake, the group, along with many other health-advocacy organizations, are proposing that the FDA strongly considers setting a safe limit on the level of sugar allowed in beverages.
In Gulf Region More Than One-Third Are Obese And One-Quarter Have Diabetes
http://mnt.to/a/4bLS
With one of the highest rates of obesity in the world, the Gulf region is facing an epidemic of cardiovascular disease. At least 50% of the population is below the age of 25 and the high prevalence of risk factors signals a massive wave of cardiovascular disease in 10-15 years.
The Effects Of Maternal Obesity On Fetal Gene Expression And Neurodevelopment
http://mnt.to/a/4bKd
In a study to be presented on February 15 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers from Tufts Medical Center will present findings showing the effects of maternal obesity on a fetus, specifically in the development of the brain.
Healthy Lifestyle And Eating During Pregnancy Help Prevent Weight Gain, Other Complications In Obese Women
http://mnt.to/a/4bKb
In a study to be presented on February 15 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest that consistent physical activity and healthier lifestyle changes beginning in a woman's first trimester can prevent excessive weight gain in obese pregnant women (with a Body Mass Index greater than 30), helping to avoid preterm delivery, hypertension and gestational diabetes.
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** OVARIAN CANCER News **
Rethink Of How Ovaries Develop
http://mnt.to/a/4bKJ
New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility.The study, now published in the journal PLOS ONE, also names a new type of cell that plays a key role in the development of ovaries and ovarian follicles, which are responsible for the production of eggs in women.
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** PARKINSON'S DISEASE News **
Caught In The Act - Protein 'Filmed' While Unfolding At Atomic Resolution
http://mnt.to/a/4bKG
By combining low temperatures and NMR spectroscopy, the scientists visualized seven intermediate forms of the CylR2 protein while cooling it down from 25°C to -16°C. Their results show that the most instable intermediate form plays a key role in protein folding.
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** PEDIATRICS / CHILDREN'S HEALTH News **
Music Lessons Early In Life Increase Brain Development
http://mnt.to/a/4bML
Playing the recorder in kindergarten, piano lessons in first grade, clapping to the rhythm throughout elementary school music class, all of these can contribute to developing the brain.The new findings, published in the Journal of Neuroscience, reveal that musical training earlier than the age of seven has a significant impact on the development of the brain.
Study Reveals Effects Of Meningitis And Septicaemia On Learning In School Children
http://mnt.to/a/4bMv
A Meningitis Research Foundation funded study has shown that meningitis and septicaemia have a significant impact on children's school performance. Their ability to learn and their behaviour are especially affected and are worse than for children treated in intensive care with other critical illnesses.
Firstborns Have Higher Risk Of Diabetes, High Blood Pressure
http://mnt.to/a/4bM4
A new study from New Zealand finds firstborn children have reduced insulin effectiveness, a known risk factor for diabetes, and higher blood pressure, compared to children who have older siblings.
High Lead Exposure May Be Behind Some Juvenile Crime
http://mnt.to/a/4bKD
Lead is a common element but is found in old paints (including those once used on children's toys), soil, old piping, water, and the atmosphere from lead-containing vehicular fuels, even drinking vessels.
Depressive Symptoms In Young Adults May Be Reduced Through Interaction With Avatars
http://mnt.to/a/4bKC
Young adults, in a period of transition, are often reluctant to seek treatment for mental health problems because of the stigma, inadequate insurance coverage and difficulty finding a mental health care provider.
Substance Abuse Rates Higher In Teenagers With ADHD: Large Study
http://mnt.to/a/4bKB
A new study published online in the Journal of the American Academy of Child and Adolescent Psychiatry revealed a significantly higher prevalence of substance abuse and cigarette use by adolescents with attention deficit hyperactivity disorder (ADHD) histories than in those without ADHD.
Harm Caused By Bullying, Whether Online Or Off
http://mnt.to/a/4bKz
Children who are bullied online or by mobile phone are just as likely to skip school or consider suicide as kids who are physically bullied, according to a study led by a Michigan State University criminologist.
Cesarean Section And Breastfeeding Practices Influence Infant Gut Microbiota, May Affect Health In Later Life
http://mnt.to/a/4bK5
Method of birth (vaginal birth s. cesarean delivery) and feeding practices (breastfeeding v. formula-feeding) influence the development of gut bacteria in newborns and thus may affect lifelong health, according to a new study in CMAJ (Canadian Medical Association Journal).
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** PREGNANCY / OBSTETRICS News **
Folic Acid Might Lower Autism Risk
http://mnt.to/a/4bLF
Women who take folic acid supplements four weeks before becoming pregnant and also during the first weeks of pregnancy have a lower risk of giving birth to children who eventually become diagnosed with an autism spectrum disorder (ASD), Norwegian researchers have reported in JAMA.
Pregnant Mothers Benefit From Preemptive Treatment Of Severe Morning Sickness
http://mnt.to/a/4bL9
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing the effectiveness of preemptive treatment for hyperemesis gravidarum and severe morning sickness.
Progesterone Shots Not Found To Reduce Preterm Delivery In Twin Pregnancies
http://mnt.to/a/4bKp
In a study to be presented on February 14 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's 33rd annual meeting, The Pregnancy Meeting ™, researchers will report findings that suggest that 17P, a form of progesterone, is not effective in preventing preterm birth among women with twin pregnancies - and may possibly be harmful.
In First Pregnancy, The Presence Of Intra-Amniotic Debris Increases Risk For Early Preterm Birth
http://mnt.to/a/4bKn
In a study to be presented on February 14 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will report findings suggesting an increased risk of early (less than 35 weeks) preterm birth when intra-amniotic debris is present in nulliparous women with a short cervix.
No Advantage Provided By Planned C-Sections Over Planned Vaginal Birth Of Twins
http://mnt.to/a/4bKm
In a study to be presented on February 14 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest that planned birthing of twins at 32-38 weeks by cesarean section does not decrease perinatal or neonatal death compared to planned vaginal birth.
Genetic Predisposition To Brain Injury After Preterm Birth May Be Sex-Specific
http://mnt.to/a/4bKk
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report that variation in a gene involved in inflammation is associated with developmental problems after preterm birth in females, but not males.
Tightening Up Of Criteria For Definition Of Intrauterine Growth Restriction Suggested By Study
http://mnt.to/a/4bKj
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report that the practice of using an arbitrary Estimated Fetal Weight (EFW) less than the 10th centile may not be an efficient practice for defining true Intrauterine Growth Restriction (IUGR).
Successful Policy Changes In Elective Delivery
http://mnt.to/a/4bKh
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing changes in elective delivery policy have been successful in reducing elective deliveries prior to 39 weeks.
Frozen Embryo Replacement (FER) Has Better Outcomes Compared To Fresh In Vitro Fertilization (IVF)
http://mnt.to/a/4bKg
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Francisco, California, researchers will present findings showing perinatal outcomes of frozen/thawed embryo replacement (FER) have better outcomes compared to fresh in vitro fertilization (IVF), but worse outcomes compared to the non-IVF general population.
Race And Ethnicity Affect Obstetric Outcomes And Care
http://mnt.to/a/4bKf
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing racial and ethnic disparities exist for adverse obstetric outcomes.
The Effects Of Maternal Obesity On Fetal Gene Expression And Neurodevelopment
http://mnt.to/a/4bKd
In a study to be presented on February 15 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers from Tufts Medical Center will present findings showing the effects of maternal obesity on a fetus, specifically in the development of the brain.
During Pregnancy, Obstructive Sleep Apnea And Cardiac Symptoms Have 31 Percent Incidence Of Cardiac Dysfunction
http://mnt.to/a/4bKc
In a study to be presented on February 15 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that women with obstructive sleep apnea (OSA) and cardiac symptoms have a 31 percent incidence of cardiac dysfunction.
Healthy Lifestyle And Eating During Pregnancy Help Prevent Weight Gain, Other Complications In Obese Women
http://mnt.to/a/4bKb
In a study to be presented on February 15 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest that consistent physical activity and healthier lifestyle changes beginning in a woman's first trimester can prevent excessive weight gain in obese pregnant women (with a Body Mass Index greater than 30), helping to avoid preterm delivery, hypertension and gestational diabetes.
Pregnancy Outcomes Improved By 'Laborist' Obstetrical Care
http://mnt.to/a/4bK9
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest shifting from a traditional model of obstetrical care to a laborist model improves pregnancy outcomes.
Decrease In C-Sections Associated With Around-The-Clock Labor Coverage
http://mnt.to/a/4bK8
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest around-the-clock labor and delivery coverage decreased the odds of cesarean delivery.
Patient Safety Improved By Comprehensive Maternal Hemorrhage Protocols
http://mnt.to/a/4bK7
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest comprehensive maternal hemorrhage protocols reduce utilization of blood products and improve patient safety.
Women Who Carry Small-For-Gestational-Age Babies In First Pregnancy At Increased Risk For Recurrence In Second Pregnancy
http://mnt.to/a/4bK6
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest women whose babies are small-for-gestational-age (SGA) in their first pregnancy have a strongly increased risk for SGA in a second pregnancy.
Cesarean Section And Breastfeeding Practices Influence Infant Gut Microbiota, May Affect Health In Later Life
http://mnt.to/a/4bK5
Method of birth (vaginal birth s. cesarean delivery) and feeding practices (breastfeeding v. formula-feeding) influence the development of gut bacteria in newborns and thus may affect lifelong health, according to a new study in CMAJ (Canadian Medical Association Journal).
Pregnant Women With High Blood Pressure At Increased Risk For Later Heart Disease
http://mnt.to/a/4bJT
High blood pressure during pregnancy - even once or twice during routine medical care - can signal substantially higher risks of heart and kidney disease and diabetes, according to new research in the American Heart Association journal Circulation.
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** PRIMARY CARE / GENERAL PRACTICE News **
Community Health Workers Improve Diabetes Outcomes And Related Behaviors
http://mnt.to/a/4bKy
Researchers who conducted a clinical trial in American Samoa to test whether community health workers could help adults with type 2 diabetes found that the patients who received the intervention were twice as likely to make a clinically meaningful improvement as those who remained with care only in the clinic.
Is Gun Violence A Public Health Issue Requiring Physician Intervention?
http://mnt.to/a/4bK4
Recent violent events have driven gun policy to the top of the President's second-term agenda.In an article being published early online in Annals of Internal Medicine, public health experts at the Johns Hopkins Center for Gun Policy and Research call for greater physician involvement in the current gun policy dialogue.
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** PROSTATE / PROSTATE CANCER News **
2013 Genitourinary Cancers Symposium: New Insights Into High-Risk Prostate Cancer; Management Of Small Kidney Tumors
http://mnt.to/a/4bLY
Research on promising new therapies and data on the relative benefits of established treatments for genitourinary cancers were released, in advance of the fourth annual Genitourinary Cancers Symposium, being held February 14-16, 2013, at the Rosen Shingle Creek in Orlando, FL.
Genetic Root To Early-Onset Prostate Cancer Identified
http://mnt.to/a/4bJZ
Prostate cancer is often considered an elderly man's disease, and little is known about the approximately 2% of cases that arise in men who are aged 50 years or younger. Research published in Cell Press journal Cancer Cell uncovers the genetic origin of such early-onset prostate cancer.
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** PSYCHOLOGY / PSYCHIATRY News **
Harm Caused By Bullying, Whether Online Or Off
http://mnt.to/a/4bKz
Children who are bullied online or by mobile phone are just as likely to skip school or consider suicide as kids who are physically bullied, according to a study led by a Michigan State University criminologist.
High Level Of Attachment Anxiety May Lower Immunity, Increase Vulnerability To Illness
http://mnt.to/a/4bKt
Concerns and anxieties about one's close relationships appear to function as a chronic stressor that can compromise immunity, according to new research. In the study, researchers asked married couples to complete questionnaires about their relationships and collected saliva and blood samples to test participants' levels of a key stress-related hormone and numbers of certain immune cells.
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** PUBLIC HEALTH News **
Limit Added Sugars In Beverages - Consumer Group Urges
http://mnt.to/a/4bMM
High levels of sugar or corn syrup in sodas are a major cause of obesity, diabetes, and other health problems, according to the Center for Science in the Public Interest (CSPI). As part of a strategy to reduce the American population's incredibly high sugar intake, the group, along with many other health-advocacy organizations, are proposing that the FDA strongly considers setting a safe limit on the level of sugar allowed in beverages.
Hospital Readmission And Death Rates Not Strongly Linked
http://mnt.to/a/4bMK
A study of over 3 million hospital admissions reveals that there is no significant association between hospital readmission and mortality rates among Medicare patients who suffer from heart attack, heart failure or pneumonia.
Vitamin D Supplement Potency Often Not What Label Says
http://mnt.to/a/4bLH
When you buy your vitamin D supplements over-the-counter be careful, they may be less potent than the labels claim, researchers from Kaiser Permanente reported in JAMA Internal Medicine.Vitamin C insufficiency can be harmful to health, hence supplementation is commonly prescribed.
Patients At Risk From Inaccurate Antibiotic Test Kits, Warns BMJ Investigation
http://mnt.to/a/4bLx
One of the world's leading producers of diagnostic tests has been falsely marketing one of their products, an investigation by the BMJ shows.Oxoid, owned by US diagnostics giant Thermofisher, has been selling antimicrobial susceptibility test (AST) discs that do not always contain the advertised amount of antibiotic.
Contrary To Popular Belief, Private Foreign Patients Are A Lucrative Source Of NHS Income, Say Experts
http://mnt.to/a/4bLv
Contrary to some media reports, more UK residents currently travel abroad for treatment than international patients travel to the UK to access NHS or private treatment here, say researchers in this week's BMJ.
Live Surgery Ethics: The Safety Of The Patient Is The Prime Consideration
http://mnt.to/a/4bKF
During the final day of the 28th Annual EAU Congress, which will take place on 15-19 March 2013 in Milan, the European Association of Urology will release its official policy statement on live surgery ethics.
High Lead Exposure May Be Behind Some Juvenile Crime
http://mnt.to/a/4bKD
Lead is a common element but is found in old paints (including those once used on children's toys), soil, old piping, water, and the atmosphere from lead-containing vehicular fuels, even drinking vessels.
Computer Simulations Set To Save Health Care
http://mnt.to/a/4bKv
New research from Indiana University has found that machine learning -- the same computer science discipline that helped create voice recognition systems, self-driving cars and credit card fraud detection systems -- can drastically improve both the cost and quality of health care in the United States.
Bed Bug Actions Study Offers Hope For New Management Tactics
http://mnt.to/a/4bKr
Learning more about the behavior of bed bugs is one approach being used by U.S. Department of Agriculture (USDA) scientists to identify compounds to help control these pests.The resurgence of bed bugs over the last decade has caused problems in major U.
Global Human Health May Be Affected By Unchecked Antibiotic Use In Animals
http://mnt.to/a/4bKq
The increasing production and use of antibiotics, about half of which are used in animal production, is mirrored by the growing number of antibiotic resistance genes, or ARGs, effectively reducing antibiotics' ability to fend off diseases - in animals and humans.
Is Gun Violence A Public Health Issue Requiring Physician Intervention?
http://mnt.to/a/4bK4
Recent violent events have driven gun policy to the top of the President's second-term agenda.In an article being published early online in Annals of Internal Medicine, public health experts at the Johns Hopkins Center for Gun Policy and Research call for greater physician involvement in the current gun policy dialogue.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
NICE Issues Preliminary Guidance To Not Recommend Jakavi™ In The Treatment Of Rare Blood Cancer As Not Cost-Effective
http://mnt.to/a/4bMw
Novartis today expressed disappointment at the National Institute for Health and Clinical Excellence's (NICE) preliminary recommendation to not recommend Jakavi™ (INC424, ruxolitinib) for the treatment of disease-related splenomegaly (enlarged spleen) or symptoms in adult patients with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post-polycythaemia vera myelofibrosis or post-essential thrombocythaemia myelofibrosis[i].
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** SCHIZOPHRENIA News **
Genes For Autism And Schizophrenia Only Active In Developing Brains
http://mnt.to/a/4bJX
Genes linked to autism and schizophrenia are only switched on during the early stages of brain development, according to a study in mice led by researchers at the University of Oxford.This new study adds to the evidence that autism and schizophrenia are neurodevelopmental disorders, a term describing conditions that originate during early brain development.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
During Pregnancy, Obstructive Sleep Apnea And Cardiac Symptoms Have 31 Percent Incidence Of Cardiac Dysfunction
http://mnt.to/a/4bKc
In a study to be presented on February 15 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that women with obstructive sleep apnea (OSA) and cardiac symptoms have a 31 percent incidence of cardiac dysfunction.
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** STROKE News **
Simulations Show How Blood Vessels Regroup After Stroke
http://mnt.to/a/4bKx
By thinking of cells as programmable robots, researchers at Rice University hope to someday direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease.
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** TUBERCULOSIS News **
Discovery Of Novel Targets And Targeting Compounds For Fighting Deadly Infectious Diseases Including MtB
http://mnt.to/a/4bMq
An international team of researchers from India, Brazil, Mexico, the USA, and Denmark led by Debmalya Barh from the Institute of Integrative Omics and Applied Biotechnology (IIOAB) in Nonakuri, Tamluk, Purba Medinipur, West Bengal, India have claimed to have identified a novel drug target (Acetate kinase) common to pathogens causing hemorrhagic diarrohea; tuberculosis, plague diphtheria, and Caseous lymphadenitis and two novel targets (Undecaprenyl pyrophosphate phosphatase enzyme and Outer membrane protein ompU) that may help to develop both a drug and a vaccine against almost all pathogenic Vibrio spp including Vibrio cholerae.
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** UROLOGY / NEPHROLOGY News **
Surveillance May Be Best For Small Kidney Tumors
http://mnt.to/a/4bMP
Surveillance, or the watch and wait approach, may be the best option for older patients with small kidney tumors.The finding came from a large retrospective study which showed that surveillance is a safe alternative to surgery.
2013 Genitourinary Cancers Symposium: New Insights Into High-Risk Prostate Cancer; Management Of Small Kidney Tumors
http://mnt.to/a/4bLY
Research on promising new therapies and data on the relative benefits of established treatments for genitourinary cancers were released, in advance of the fourth annual Genitourinary Cancers Symposium, being held February 14-16, 2013, at the Rosen Shingle Creek in Orlando, FL.
Live Surgery Ethics: The Safety Of The Patient Is The Prime Consideration
http://mnt.to/a/4bKF
During the final day of the 28th Annual EAU Congress, which will take place on 15-19 March 2013 in Milan, the European Association of Urology will release its official policy statement on live surgery ethics.
----------------------------------------------
** VASCULAR News **
Vascular Brain Injury Greater Risk Factor Than Amyloid Plaques In Cognitive Aging
http://mnt.to/a/4bMp
Vascular brain injury from conditions such as high blood pressure and stroke are greater risk factors for cognitive impairment among non-demented older people than is the deposition of the amyloid plaques in the brain that long have been implicated in conditions such as Alzheimer's disease, a study by researchers at the Alzheimer's Disease Research Center at UC Davis has found.
Simulations Show How Blood Vessels Regroup After Stroke
http://mnt.to/a/4bKx
By thinking of cells as programmable robots, researchers at Rice University hope to someday direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease.
----------------------------------------------
** WATER - AIR QUALITY / AGRICULTURE News **
Environmental Engineers Seek Strategy To Control Antibiotic Resistant Genes
http://mnt.to/a/4bKK
Rice University researchers "cured" a strain of bacteria of its ability to resist an antibiotic in an experiment that has implications for a long-standing public health crisis.Rice environmental engineer Pedro Alvarez and his team managed to remove the ability of the Pseudomonas aeruginosa microorganism to resist the antibiotic medication tetracycline by limiting its access to food and oxygen.
Global Human Health May Be Affected By Unchecked Antibiotic Use In Animals
http://mnt.to/a/4bKq
The increasing production and use of antibiotics, about half of which are used in animal production, is mirrored by the growing number of antibiotic resistance genes, or ARGs, effectively reducing antibiotics' ability to fend off diseases - in animals and humans.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Risk Of Cardiovascular Death Doubled In Women With High Calcium Intake - High Risk Only In Those Taking Supplements
http://mnt.to/a/4bLw
High intakes of calcium (corresponding to diet and supplements) in women are associated with a higher risk of death from all causes, but cardiovascular disease in particular, compared with women with lower calcium intake, a study published today on bmj.
Rethink Of How Ovaries Develop
http://mnt.to/a/4bKJ
New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility.The study, now published in the journal PLOS ONE, also names a new type of cell that plays a key role in the development of ovaries and ovarian follicles, which are responsible for the production of eggs in women.
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