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** ALZHEIMER'S / DEMENTIA News **
Brain Lesions Can Predict Alzheimer's Diagnosis
http://mnt.to/a/4bSv
Damage to small blood vessels in the brain could be a secondary risk factor leading to Alzheimer's Disease, a new study in JAMA Neurology suggests.A part of this blood vessel damage is known as white matter hyperintensities, seen in the brains of Alzheimer's patients and appearing to increase the risk for the disease, making it a secondary factor.
Spherical Nucleic Acids Have Novel Properties That Are Perfect For Biomedical Applications
http://mnt.to/a/4bQT
Northwestern University's Chad A. Mirkin, a world-renowned leader in nanotechnology research and its application, has invented and developed a powerful material that could revolutionize biomedicine: spherical nucleic acids (SNAs).
Potential To Prevent And Treat Alzheimer's Disease Offered By Novel Herbal Compound
http://mnt.to/a/4bQH
Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.
Tau Release From Healthy Neurons Induced By Neuronal Activity
http://mnt.to/a/4bQp
Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The results published by Diane Hanger and her colleagues in EMBO reports show that treatment of neurons with known biological signaling molecules increases the release of tau into the culture medi-um.
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** ANXIETY / STRESS News **
Children With Poor Stress Responses Often Eat In The Absence Of Hunger, Increasing Risk Of Obesity
http://mnt.to/a/4bQb
Children who overreact to stressors may be at risk of becoming overweight or obese, according to researchers at Penn State and Johns Hopkins University."Our results suggest that some children who are at risk of becoming obese can be identified by their biological response to a stressor," said Lori Francis, associate professor of biobehavioral health.
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** AUTISM News **
Seeking Roots Of Obsessive Behavior, Motion Disorders
http://mnt.to/a/4bQG
Learning, memory and habits are encoded in the strength of connections between neurons in the brain, the synapses. These connections aren't meant to be fixed, they're changeable, or plastic.Duke University neurologist and neuroscientist Nicole Calakos studies what happens when those connections aren't as adaptable as they should be in the basal ganglia, the brain's "command center" for turning information into actions.
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** BIOLOGY / BIOCHEMISTRY News **
UN Warns Of Hormone-Disrupting Chemicals In Domestic Products
http://mnt.to/a/4bSx
Hormone-disrupting chemicals found in domestic and industrial products which have not been properly tested may result in significant health problems.The finding was reported by the United Nations Environment Program (UNEP) and WHO (World Health Organization).
Gene Enables Cells To Survive Even If Growth Stops
http://mnt.to/a/4bR4
Researchers in Australia have discovered a genetic defect that can stop cells growing but forces them into a death-defying state where they consume their own cellular material to survive. They believe the discovery of such an important feature of cell growth could lead to new treatments for diseases, including cancer.
Biologists And Physicists Produce Revealing Images Of Cell Organization, Behavior - Seeing Is Believing
http://mnt.to/a/4bQF
When difficult biological questions are tackled by creative experts in physics, what can result?Images of great beauty, accessible for anyone to appreciate, that also offer rich information on fundamental life processes, and rewarding new paths for analysis and insight.
Adhesive Protein Inspired By Mussels Harnessed For Biomedical Applications
http://mnt.to/a/4bQD
When it comes to sticking power under wet conditions, marine mussels are hard to beat. They can adhere to virtually all inorganic and organic surfaces, sustaining their tenacious bonds in saltwater, including turbulent tidal environments.
Single Molecule Sieves Developed To Separate Complex Molecular Mixtures
http://mnt.to/a/4bQv
Chemists at the University of Liverpool have created a new technique that could be used in industry to separate complex organic chemical mixtures.Chemical feedstocks containing benzene are used extensively in industry to create modern materials and polymers.
Nano-Machines For 'Bionic Proteins'
http://mnt.to/a/4bQt
Physicists of the University of Vienna together with researchers from the University of Natural Resources and Life Sciences Vienna developed nano-machines which recreate principal activities of proteins.
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** BLOOD / HEMATOLOGY News **
Intravenous Fluid Used To Increase Blood Volume In Critically Ill Patients Associated With Increased Risk Of Death, Kidney Injury
http://mnt.to/a/4bRn
In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous use of the fluid hydroxyethyl starch, compared with other resuscitation solutions, was not associated with decreased mortality, according to an article appearing in the February 20 issue of JAMA.
Designer Blood Clots Could Help Injured Soldiers On The Battlefield
http://mnt.to/a/4bQS
When it comes to healing the terrible wounds of war, success may hinge on the first blood clot - the one that begins forming on the battlefield right after an injury.Researchers exploring the complex stream of cellular signals produced by the body in response to a traumatic injury believe the initial response - formation of a blood clot - may control subsequent healing.
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** BONES / ORTHOPEDICS News **
Hip Implant Failure More Likely In Women
http://mnt.to/a/4bRh
A new study of 35,000 US patients, one of the largest of its kind, suggests while the risk of total hip implant failure is low, it is slightly higher in women than in men. It has prompted calls for studies to investigate which types of implants are more likely to succeed in women than men.
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** BREAST CANCER News **
Promising New Approach To Preventing Progression Of Breast Cancer
http://mnt.to/a/4bQN
Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode - an issue with profound implications for treatment. Now a group from The Scripps Research Institute (TSRI) has identified a mechanism through which mitochondria, the powerhouses of a cell, control tumor aggressiveness.
Current Model For Breast Cancer Risk Prediction In African American Women Underestimates Risk
http://mnt.to/a/4bQr
A breast cancer risk prediction model developed for African Americans tends to underestimate risk in certain subgroups, according to a new study from the Slone Epidemiology Center (SEC) at Boston University.
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** CANCER / ONCOLOGY News **
Dako Receives FDA Approval For Fast, Accurate, Nontoxic FISH Assay For Cancer Diagnostics
http://mnt.to/a/4bRx
Dako, an Agilent Technologies Company, has introduced IQISH technology in the United States. The technology will reduce the turnaround time for cancer evaluation from two days to three and a half hours.
Gene Enables Cells To Survive Even If Growth Stops
http://mnt.to/a/4bR4
Researchers in Australia have discovered a genetic defect that can stop cells growing but forces them into a death-defying state where they consume their own cellular material to survive. They believe the discovery of such an important feature of cell growth could lead to new treatments for diseases, including cancer.
Adhesive Protein Inspired By Mussels Harnessed For Biomedical Applications
http://mnt.to/a/4bQD
When it comes to sticking power under wet conditions, marine mussels are hard to beat. They can adhere to virtually all inorganic and organic surfaces, sustaining their tenacious bonds in saltwater, including turbulent tidal environments.
Tool Tested For Screening Cancer Patients For Malnutrition
http://mnt.to/a/4bQf
Considering the many things a cancer patient has to think about, it's easy to understand why maintaining proper nutrition may not be top of the list.This can be true, too, at busy outpatient settings where it's often difficult to find the time and resources to test cancer patients for malnutrition.
Patient-Specific Cancer Cell Lines Designed To Predict Chemotherapy Sensitivity
http://mnt.to/a/4bPW
In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
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** CARDIOVASCULAR / CARDIOLOGY News **
New Research Shows 'Flutter' Of Inactivity As Americans Ignore Warning Signs Of Atrial Fibrillation
http://mnt.to/a/4bRK
The Heart Rhythm Society Calls on all Americans to Know Risks and Warning Signs of the Most Common Arrhythmia during Heart Health Month While the majority of Americans are at least aware of atrial fibrillation (AF), many may be unable to identify or may even ignore the warning signs of the disorder.
Analysis Links Ozone Levels, Cardiac Arrest
http://mnt.to/a/4bQK
Researchers at Rice University in Houston have found a direct correlation between out-of-hospital cardiac arrests and levels of air pollution and ozone. Their work has prompted more CPR training in at-risk communities.
Diabetes And Increased Risk Of Heart Attack Death Linked
http://mnt.to/a/4bQg
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.
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** CLINICAL TRIALS / DRUG TRIALS News **
Gilead's Hepatitis C Drug Shows Promise In Final Phase 3 Study
http://mnt.to/a/4bSy
Gildead Sciences has just announced that its experimental hepatitis C drug, called sofosbuvir, successfully met its primary efficacy endpoint in a fourth pivotal phase 3 study called FUSION. The drug, an oral nucleotide inhibitor of HCV polymerase, performed very well in the late-stage trial testing.
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** DENTISTRY News **
Modern Diet Is Rotting Our Teeth
http://mnt.to/a/4bR3
A study of the evolution of our teeth over the last 7,500 years shows that humans today have less diverse oral bacteria than historic populations, which scientists believe have contributed to chronic oral diseases in post-industrial lifestyles.
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** DERMATOLOGY News **
Researchers Uncover New Findings On Genetic Risks Of Chronic Inflammatory Disorder Behçet's Disease
http://mnt.to/a/4bRB
Researchers don't know the exact cause of Behçet's disease, a chronic condition that leads to oral and genital sores and serious complications such as blindness, but new research brings better understanding to what makes some people more susceptible to being affected.
Mismatch Between Sun Exposure In Modern Life And Skin Pigmentation
http://mnt.to/a/4bQy
As people move more often and become more urbanized, skin color -- an adaptation that took hundreds of thousands of years to develop in humans -- may lose some of its evolutionary advantage, according to a Penn State anthropologist.
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** DIABETES News **
Big Improvement Seen In Diabetes Control Over Past Decades
http://mnt.to/a/4bQR
More people are meeting recommended goals in the three key markers of diabetes control, according to a study conducted and funded by the National Institutes of Health and the Centers for Disease Control and Prevention.
Diabetes And Increased Risk Of Heart Attack Death Linked
http://mnt.to/a/4bQg
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.
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** ENDOCRINOLOGY News **
Meta-Analyses Of Bisphenol A Studies Show Human Exposure Is Likely To Be Too Low For Estrogenic Effects
http://mnt.to/a/4bQV
A controversial component of plastic bottles and canned food linings that have helped make the world's food supply safer has recently come under attack: bisphenol A. Widely known as BPA, it has the potential to mimic the sex hormone estrogen if blood and tissue levels are high enough.
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** ERECTILE DYSFUNCTION / PREMATURE EJACULATION News **
'Big Pharma' Fails At Self-Policing ED Drug Advertising: Study
http://mnt.to/a/4bQM
The pharmaceutical industry's efforts to self-regulate its direct-to-consumer (DTC) advertising are "an industry-sponsored ruse," intended to deflect criticism and collectively block new Federal regulation, a study released in the Journal of Health Politics, Policy and Law found.
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** EYE HEALTH / BLINDNESS News **
Potential Link Revealed Between Parkinson's And Visual Problems
http://mnt.to/a/4bQm
The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.
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** FLU / COLD / SARS News **
Novel Coronavirus Infection Death Reported In UK
http://mnt.to/a/4bRS
A patient who was being treated at Queen Elizabeth Hospital Birmingham (QEHB), England, for novel coronavirus (NCoV) infection has died, the hospital has announced today.The patient passed away in the hospital's critical care unit on Sunday morning.
What Are Coronaviruses? What Do Coronaviruses Cause?
http://mnt.to/a/4bR8
Coronaviruses are viruses that belong to the subfamily Coronavirinae in the family Coronaviridae that typically affect the respiratory tract of mammals, including humans - they are associated with the common cold, pneumonia and severe acute respiratory syndrome (SARS).
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** GENETICS News **
Researchers Uncover New Findings On Genetic Risks Of Chronic Inflammatory Disorder Behçet's Disease
http://mnt.to/a/4bRB
Researchers don't know the exact cause of Behçet's disease, a chronic condition that leads to oral and genital sores and serious complications such as blindness, but new research brings better understanding to what makes some people more susceptible to being affected.
Association Found Between Length Of Biological Marker And Development Of Respiratory Infection In Healthy Adults
http://mnt.to/a/4bRq
Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.
Gene Enables Cells To Survive Even If Growth Stops
http://mnt.to/a/4bR4
Researchers in Australia have discovered a genetic defect that can stop cells growing but forces them into a death-defying state where they consume their own cellular material to survive. They believe the discovery of such an important feature of cell growth could lead to new treatments for diseases, including cancer.
Modern Diet Is Rotting Our Teeth
http://mnt.to/a/4bR3
A study of the evolution of our teeth over the last 7,500 years shows that humans today have less diverse oral bacteria than historic populations, which scientists believe have contributed to chronic oral diseases in post-industrial lifestyles.
Study Identifies Regions Of Genes Linked To Behçet's Disease
http://mnt.to/a/4bQq
Researchers don't know the exact cause of Behçet's disease, a chronic condition that leads to oral and genital sores and serious complications such as blindness, but new research brings better understanding to what makes some people more susceptible to being affected.
New Enzyme Discovered That Acts As Innate Immunity Sensor
http://mnt.to/a/4bQn
Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.
Potential Link Revealed Between Parkinson's And Visual Problems
http://mnt.to/a/4bQm
The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.
In Both Humans And Dogs, The Same Genetic Defect Causes Pompe Disease
http://mnt.to/a/4bQj
Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans.
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** HEART DISEASE News **
St. Jude Medical Initiates Landmark Study Of Renal Denervation For Reduction Of Heart Attack, Stroke And Death
http://mnt.to/a/4bRH
EnligHTNment trial will evaluate whether patients with hypertension that are treated with renal denervation and medication experience additional benefits beyond a reduction in blood pressureSt.
Diabetes And Increased Risk Of Heart Attack Death Linked
http://mnt.to/a/4bQg
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.
----------------------------------------------
** HUNTINGTONS DISEASE News **
Seeking Roots Of Obsessive Behavior, Motion Disorders
http://mnt.to/a/4bQG
Learning, memory and habits are encoded in the strength of connections between neurons in the brain, the synapses. These connections aren't meant to be fixed, they're changeable, or plastic.Duke University neurologist and neuroscientist Nicole Calakos studies what happens when those connections aren't as adaptable as they should be in the basal ganglia, the brain's "command center" for turning information into actions.
----------------------------------------------
** IMMUNE SYSTEM / VACCINES News **
Researchers Uncover New Findings On Genetic Risks Of Chronic Inflammatory Disorder Behçet's Disease
http://mnt.to/a/4bRB
Researchers don't know the exact cause of Behçet's disease, a chronic condition that leads to oral and genital sores and serious complications such as blindness, but new research brings better understanding to what makes some people more susceptible to being affected.
Study Identifies Regions Of Genes Linked To Behçet's Disease
http://mnt.to/a/4bQq
Researchers don't know the exact cause of Behçet's disease, a chronic condition that leads to oral and genital sores and serious complications such as blindness, but new research brings better understanding to what makes some people more susceptible to being affected.
----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Gilead's Hepatitis C Drug Shows Promise In Final Phase 3 Study
http://mnt.to/a/4bSy
Gildead Sciences has just announced that its experimental hepatitis C drug, called sofosbuvir, successfully met its primary efficacy endpoint in a fourth pivotal phase 3 study called FUSION. The drug, an oral nucleotide inhibitor of HCV polymerase, performed very well in the late-stage trial testing.
Novel Coronavirus Infection Death Reported In UK
http://mnt.to/a/4bRS
A patient who was being treated at Queen Elizabeth Hospital Birmingham (QEHB), England, for novel coronavirus (NCoV) infection has died, the hospital has announced today.The patient passed away in the hospital's critical care unit on Sunday morning.
Association Found Between Length Of Biological Marker And Development Of Respiratory Infection In Healthy Adults
http://mnt.to/a/4bRq
Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.
What Are Coronaviruses? What Do Coronaviruses Cause?
http://mnt.to/a/4bR8
Coronaviruses are viruses that belong to the subfamily Coronavirinae in the family Coronaviridae that typically affect the respiratory tract of mammals, including humans - they are associated with the common cold, pneumonia and severe acute respiratory syndrome (SARS).
New Computational Model Demonstrates How Disease Spreads In A Highly Connected World
http://mnt.to/a/4bQB
In a world of increasing global connections, predicting the spread of infectious diseases is more complicated than ever. Pandemics no longer follow the patterns they did centuries ago, when diseases swept through populations town by town; instead, they spread quickly and seemingly at random, spurred by the interactions of 3 billion air travelers per year.
New Enzyme Discovered That Acts As Innate Immunity Sensor
http://mnt.to/a/4bQn
Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.
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** LIVER DISEASE / HEPATITIS News **
Gilead's Hepatitis C Drug Shows Promise In Final Phase 3 Study
http://mnt.to/a/4bSy
Gildead Sciences has just announced that its experimental hepatitis C drug, called sofosbuvir, successfully met its primary efficacy endpoint in a fourth pivotal phase 3 study called FUSION. The drug, an oral nucleotide inhibitor of HCV polymerase, performed very well in the late-stage trial testing.
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** LUNG CANCER News **
Potential New Therapeutic Target For Treating Non-Small Cell Lung Cancer
http://mnt.to/a/4bQP
Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response.
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** LUPUS News **
New Enzyme Discovered That Acts As Innate Immunity Sensor
http://mnt.to/a/4bQn
Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.
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** MEDICAL DEVICES / DIAGNOSTICS News **
Dako Receives FDA Approval For Fast, Accurate, Nontoxic FISH Assay For Cancer Diagnostics
http://mnt.to/a/4bRx
Dako, an Agilent Technologies Company, has introduced IQISH technology in the United States. The technology will reduce the turnaround time for cancer evaluation from two days to three and a half hours.
U.S. FDA Approval Of Aorfix™
http://mnt.to/a/4bRw
Lombard Medical Technologies PLC (AIM: LMT), the specialist medical technology company focused on innovative vascular products, has announced that Aorfix™ has been approved for commercial sale in the U.
Increase Seen In Use Of Robotically-Assisted Hysterectomy For Benign Gynecologic Disorders
http://mnt.to/a/4bRp
Between 2007 and 2010, the use of robotically-assisted hysterectomy for benign gynecologic disorders increased substantially, although, when compared with laparoscopic hysterectomy, the robotic procedure appears to offer little short-term benefit and is accompanied by significantly greater costs, according to a study appearing in the February 20 issue of JAMA.
Biologists And Physicists Produce Revealing Images Of Cell Organization, Behavior - Seeing Is Believing
http://mnt.to/a/4bQF
When difficult biological questions are tackled by creative experts in physics, what can result?Images of great beauty, accessible for anyone to appreciate, that also offer rich information on fundamental life processes, and rewarding new paths for analysis and insight.
Tool Tested For Screening Cancer Patients For Malnutrition
http://mnt.to/a/4bQf
Considering the many things a cancer patient has to think about, it's easy to understand why maintaining proper nutrition may not be top of the list.This can be true, too, at busy outpatient settings where it's often difficult to find the time and resources to test cancer patients for malnutrition.
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** MEDICARE / MEDICAID / SCHIP News **
Viewpoints, February 20 Issue Of JAMA - US Health Care, Access & Reimbursement Policy And Atherosclerotic Renal Artery Stenosis Treatment
http://mnt.to/a/4bRs
Reengineering U.S. Health CareAri Hoffman, M.D., of the University of California, San Francisco, and Ezekiel J. Emanuel, M.D., Ph.D., of the University of Pennsylvania, Philadelphia, write that "health reform requires fixing a chronically dysfunctional system.
Hospitals May Be Unfairly Punished For High Readmission Rates
http://mnt.to/a/4bQk
When hospital patients have to be readmitted soon after discharge, hospitals look bad.A high readmission rate also can result in reduced Medicare reimbursements. But a study of spine surgery patients has found that the standard method used to calculate readmission rates is a misleading indicator of hospital quality.
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** NEUROLOGY / NEUROSCIENCE News **
Brain Lesions Can Predict Alzheimer's Diagnosis
http://mnt.to/a/4bSv
Damage to small blood vessels in the brain could be a secondary risk factor leading to Alzheimer's Disease, a new study in JAMA Neurology suggests.A part of this blood vessel damage is known as white matter hyperintensities, seen in the brains of Alzheimer's patients and appearing to increase the risk for the disease, making it a secondary factor.
Spherical Nucleic Acids Have Novel Properties That Are Perfect For Biomedical Applications
http://mnt.to/a/4bQT
Northwestern University's Chad A. Mirkin, a world-renowned leader in nanotechnology research and its application, has invented and developed a powerful material that could revolutionize biomedicine: spherical nucleic acids (SNAs).
Physical Activity Really Does Enhance Cognition
http://mnt.to/a/4bQC
Exercise doesn't only strengthen your heart and muscles - it also beefs up your brain. Dozens of studies now show that aerobic exercise can increase the size of critical brain structures and improve cognition in children and older adults.
New Frontiers In Trauma And Stroke Recovery: Teaching The Brain To Speak Again
http://mnt.to/a/4bQz
Cynthia Thompson, a world-renowned researcher on stroke and brain damage, discussed her groundbreaking research on aphasia and the neurolinguistic systems it affects at the annual meeting of the American Association for the Advancement of Science (AAAS).
Long-Term Follow-Up Essential For Players Who Have Suffered Concussions
http://mnt.to/a/4bQw
As the National Football League braces for lawsuits by 4000 former players alleging the league failed to protect them from the long-term consequences of concussions, game-changing research by a leading Canadian researcher shows damage to the brain can persist for decades after the original head trauma.
Tau Release From Healthy Neurons Induced By Neuronal Activity
http://mnt.to/a/4bQp
Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The results published by Diane Hanger and her colleagues in EMBO reports show that treatment of neurons with known biological signaling molecules increases the release of tau into the culture medi-um.
Hospitals May Be Unfairly Punished For High Readmission Rates
http://mnt.to/a/4bQk
When hospital patients have to be readmitted soon after discharge, hospitals look bad.A high readmission rate also can result in reduced Medicare reimbursements. But a study of spine surgery patients has found that the standard method used to calculate readmission rates is a misleading indicator of hospital quality.
----------------------------------------------
** NUTRITION / DIET News **
Caffeine During Pregnancy Associated With Low Birth Weight Babies
http://mnt.to/a/4bR7
Caffeine consumption during pregnancy is linked to low birth weight babies as well as an overall increase in the length of gestation, reveals new research published in the journal BMC Medicine.
Breastfeeding All Newborns Could Save 830,000 Lives A Year
http://mnt.to/a/4bR6
If all mothers breastfed their newborns straight away after they were born, about 830,000 lives annually would be saved, says Save the Children in a new report. The authors added that there are four major barriers to better breastfeeding.
Modern Diet Is Rotting Our Teeth
http://mnt.to/a/4bR3
A study of the evolution of our teeth over the last 7,500 years shows that humans today have less diverse oral bacteria than historic populations, which scientists believe have contributed to chronic oral diseases in post-industrial lifestyles.
Mismatch Between Sun Exposure In Modern Life And Skin Pigmentation
http://mnt.to/a/4bQy
As people move more often and become more urbanized, skin color -- an adaptation that took hundreds of thousands of years to develop in humans -- may lose some of its evolutionary advantage, according to a Penn State anthropologist.
Taking A New Look At An Urban Area's Access To Healthier Foods
http://mnt.to/a/4bQs
University of Cincinnati-led research takes a new direction in examining the availability of healthy foods for urban populations by examining the commuting patterns of its residents. This new approach to identifying so-called food deserts, now published online, will appear in the May journal of Health and Place.
Tool Tested For Screening Cancer Patients For Malnutrition
http://mnt.to/a/4bQf
Considering the many things a cancer patient has to think about, it's easy to understand why maintaining proper nutrition may not be top of the list.This can be true, too, at busy outpatient settings where it's often difficult to find the time and resources to test cancer patients for malnutrition.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
Promising Approaches To Prevent Latino Childhood Obesity
http://mnt.to/a/4bQQ
Guided grocery store trips, menu labeling at restaurants, community gardens, and video-game-based exercise programs are among several promising, culturally appropriate ways to prevent obesity among Latino children, according to a new collection of studies from Salud America! The Robert Wood Johnson Foundation Research Network to Prevent Obesity Among Latino Children published in a supplement to the March issue of the American Journal of Preventive Medicine.
Children With Poor Stress Responses Often Eat In The Absence Of Hunger, Increasing Risk Of Obesity
http://mnt.to/a/4bQb
Children who overreact to stressors may be at risk of becoming overweight or obese, according to researchers at Penn State and Johns Hopkins University."Our results suggest that some children who are at risk of becoming obese can be identified by their biological response to a stressor," said Lori Francis, associate professor of biobehavioral health.
Negative Obesity Coverage In Black Newspapers Could Discourage African-American Community From Taking Action
http://mnt.to/a/4bPX
Obesity rates have increased dramatically in the last few decades. According to the U.S. Census Bureau, while African Americans are only 13 percent of the total population, 82 percent of black women are overweight or obese compared to nearly 60 percent of white women, and more than 70 percent of black males are classified as overweight or obese.
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** OVARIAN CANCER News **
Patient-Specific Cancer Cell Lines Designed To Predict Chemotherapy Sensitivity
http://mnt.to/a/4bPW
In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
----------------------------------------------
** PAIN / ANESTHETICS News **
Opioid Analgesics Involved In Most Pharmaceutical Overdose Deaths
http://mnt.to/a/4bRr
"Data recently released by the National Center for Health Statistics show drug overdose deaths increased for the 11th consecutive year in 2010. Pharmaceuticals, especially opioid analgesics, have driven this increase.
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** PANCREATIC CANCER News **
Patient-Specific Cancer Cell Lines Designed To Predict Chemotherapy Sensitivity
http://mnt.to/a/4bPW
In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
----------------------------------------------
** PARKINSON'S DISEASE News **
Spherical Nucleic Acids Have Novel Properties That Are Perfect For Biomedical Applications
http://mnt.to/a/4bQT
Northwestern University's Chad A. Mirkin, a world-renowned leader in nanotechnology research and its application, has invented and developed a powerful material that could revolutionize biomedicine: spherical nucleic acids (SNAs).
Potential Link Revealed Between Parkinson's And Visual Problems
http://mnt.to/a/4bQm
The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.
----------------------------------------------
** PEDIATRICS / CHILDREN'S HEALTH News **
Excessive TV Watching During Childhood Linked To Criminal Behavior Risk Later
http://mnt.to/a/4bSt
Watching a lot of television as a kid may lead to violent behavior later in life, according to a new study carried out by researchers from the University of Otago. The study, published in the journal Pediatrics, identified that children and adolescents who spend an excessive amount of time watching television are more likely to express antisocial behaviors, as well as involve themselves in criminal activity when they are adults.
Breastfeeding All Newborns Could Save 830,000 Lives A Year
http://mnt.to/a/4bR6
If all mothers breastfed their newborns straight away after they were born, about 830,000 lives annually would be saved, says Save the Children in a new report. The authors added that there are four major barriers to better breastfeeding.
Promising Approaches To Prevent Latino Childhood Obesity
http://mnt.to/a/4bQQ
Guided grocery store trips, menu labeling at restaurants, community gardens, and video-game-based exercise programs are among several promising, culturally appropriate ways to prevent obesity among Latino children, according to a new collection of studies from Salud America! The Robert Wood Johnson Foundation Research Network to Prevent Obesity Among Latino Children published in a supplement to the March issue of the American Journal of Preventive Medicine.
Children With Poor Stress Responses Often Eat In The Absence Of Hunger, Increasing Risk Of Obesity
http://mnt.to/a/4bQb
Children who overreact to stressors may be at risk of becoming overweight or obese, according to researchers at Penn State and Johns Hopkins University."Our results suggest that some children who are at risk of becoming obese can be identified by their biological response to a stressor," said Lori Francis, associate professor of biobehavioral health.
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** PHARMA INDUSTRY / BIOTECH INDUSTRY News **
'Big Pharma' Fails At Self-Policing ED Drug Advertising: Study
http://mnt.to/a/4bQM
The pharmaceutical industry's efforts to self-regulate its direct-to-consumer (DTC) advertising are "an industry-sponsored ruse," intended to deflect criticism and collectively block new Federal regulation, a study released in the Journal of Health Politics, Policy and Law found.
A New Way Of Looking At Drug Discovery
http://mnt.to/a/4bQx
Garret FitzGerald, MD, FRS, chair of the Department of Pharmacology and Director of the Institute for Translational Medicine & Therapeutics, Perelman School of Medicine at the University of Pennsylvania, has long said the current drug-development system in the United States is in need of change, "representing an unsustainable model.
Single Molecule Sieves Developed To Separate Complex Molecular Mixtures
http://mnt.to/a/4bQv
Chemists at the University of Liverpool have created a new technique that could be used in industry to separate complex organic chemical mixtures.Chemical feedstocks containing benzene are used extensively in industry to create modern materials and polymers.
Nano-Machines For 'Bionic Proteins'
http://mnt.to/a/4bQt
Physicists of the University of Vienna together with researchers from the University of Natural Resources and Life Sciences Vienna developed nano-machines which recreate principal activities of proteins.
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** PHARMACY / PHARMACIST News **
Opioid Analgesics Involved In Most Pharmaceutical Overdose Deaths
http://mnt.to/a/4bRr
"Data recently released by the National Center for Health Statistics show drug overdose deaths increased for the 11th consecutive year in 2010. Pharmaceuticals, especially opioid analgesics, have driven this increase.
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** PREGNANCY / OBSTETRICS News **
Caffeine During Pregnancy Associated With Low Birth Weight Babies
http://mnt.to/a/4bR7
Caffeine consumption during pregnancy is linked to low birth weight babies as well as an overall increase in the length of gestation, reveals new research published in the journal BMC Medicine.
Breastfeeding All Newborns Could Save 830,000 Lives A Year
http://mnt.to/a/4bR6
If all mothers breastfed their newborns straight away after they were born, about 830,000 lives annually would be saved, says Save the Children in a new report. The authors added that there are four major barriers to better breastfeeding.
Looking At Our Evolutionary Past To Understand Today's Health Problems
http://mnt.to/a/4bQL
Bunions bothering you? How about lower back pain, or impacted wisdom teeth? As we humans evolved over the millennia to walk on two legs, grow larger brains and shorter jaws, bear big babies and live longer, we've also experienced some negative consequences on our way to becoming the world's most successful primate, at nearly 7 billion strong.
Adhesive Protein Inspired By Mussels Harnessed For Biomedical Applications
http://mnt.to/a/4bQD
When it comes to sticking power under wet conditions, marine mussels are hard to beat. They can adhere to virtually all inorganic and organic surfaces, sustaining their tenacious bonds in saltwater, including turbulent tidal environments.
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** PREVENTIVE MEDICINE News **
Promising Approaches To Prevent Latino Childhood Obesity
http://mnt.to/a/4bQQ
Guided grocery store trips, menu labeling at restaurants, community gardens, and video-game-based exercise programs are among several promising, culturally appropriate ways to prevent obesity among Latino children, according to a new collection of studies from Salud America! The Robert Wood Johnson Foundation Research Network to Prevent Obesity Among Latino Children published in a supplement to the March issue of the American Journal of Preventive Medicine.
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** PRIMARY CARE / GENERAL PRACTICE News **
Opioid Analgesics Involved In Most Pharmaceutical Overdose Deaths
http://mnt.to/a/4bRr
"Data recently released by the National Center for Health Statistics show drug overdose deaths increased for the 11th consecutive year in 2010. Pharmaceuticals, especially opioid analgesics, have driven this increase.
----------------------------------------------
** PSYCHOLOGY / PSYCHIATRY News **
Excessive TV Watching During Childhood Linked To Criminal Behavior Risk Later
http://mnt.to/a/4bSt
Watching a lot of television as a kid may lead to violent behavior later in life, according to a new study carried out by researchers from the University of Otago. The study, published in the journal Pediatrics, identified that children and adolescents who spend an excessive amount of time watching television are more likely to express antisocial behaviors, as well as involve themselves in criminal activity when they are adults.
Seeking Roots Of Obsessive Behavior, Motion Disorders
http://mnt.to/a/4bQG
Learning, memory and habits are encoded in the strength of connections between neurons in the brain, the synapses. These connections aren't meant to be fixed, they're changeable, or plastic.Duke University neurologist and neuroscientist Nicole Calakos studies what happens when those connections aren't as adaptable as they should be in the basal ganglia, the brain's "command center" for turning information into actions.
Emotional Response From Billboards Can Affect Our Driving Abilities
http://mnt.to/a/4bPV
There's a billboard up ahead, a roadside sign full of language and imagery. Next stop: the emotionally distracted zone.One University of Alberta researcher has discovered that language used on billboards can provoke an emotional response that affects our driving abilities.
Women's Social Activism May Be Inhibited By Self-Objectification
http://mnt.to/a/4bPT
Women who live in a culture in which they are objectified by others may in turn begin to objectify themselves. This kind of self-objectification may reduce women's involvement in social activism, according to new research published in Psychological Science, a journal of the Association for Psychological Science.
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** PUBLIC HEALTH News **
UN Warns Of Hormone-Disrupting Chemicals In Domestic Products
http://mnt.to/a/4bSx
Hormone-disrupting chemicals found in domestic and industrial products which have not been properly tested may result in significant health problems.The finding was reported by the United Nations Environment Program (UNEP) and WHO (World Health Organization).
Viewpoints, February 20 Issue Of JAMA - US Health Care, Access & Reimbursement Policy And Atherosclerotic Renal Artery Stenosis Treatment
http://mnt.to/a/4bRs
Reengineering U.S. Health CareAri Hoffman, M.D., of the University of California, San Francisco, and Ezekiel J. Emanuel, M.D., Ph.D., of the University of Pennsylvania, Philadelphia, write that "health reform requires fixing a chronically dysfunctional system.
Intravenous Fluid Used To Increase Blood Volume In Critically Ill Patients Associated With Increased Risk Of Death, Kidney Injury
http://mnt.to/a/4bRn
In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous use of the fluid hydroxyethyl starch, compared with other resuscitation solutions, was not associated with decreased mortality, according to an article appearing in the February 20 issue of JAMA.
Meta-Analyses Of Bisphenol A Studies Show Human Exposure Is Likely To Be Too Low For Estrogenic Effects
http://mnt.to/a/4bQV
A controversial component of plastic bottles and canned food linings that have helped make the world's food supply safer has recently come under attack: bisphenol A. Widely known as BPA, it has the potential to mimic the sex hormone estrogen if blood and tissue levels are high enough.
Designer Blood Clots Could Help Injured Soldiers On The Battlefield
http://mnt.to/a/4bQS
When it comes to healing the terrible wounds of war, success may hinge on the first blood clot - the one that begins forming on the battlefield right after an injury.Researchers exploring the complex stream of cellular signals produced by the body in response to a traumatic injury believe the initial response - formation of a blood clot - may control subsequent healing.
Looking At Our Evolutionary Past To Understand Today's Health Problems
http://mnt.to/a/4bQL
Bunions bothering you? How about lower back pain, or impacted wisdom teeth? As we humans evolved over the millennia to walk on two legs, grow larger brains and shorter jaws, bear big babies and live longer, we've also experienced some negative consequences on our way to becoming the world's most successful primate, at nearly 7 billion strong.
Associations Explored Between Air Pollution And Health Outcomes
http://mnt.to/a/4bQJ
Lance Waller, PhD, chair of Biostatistics and Bioinformatics at Emory's Rollins School of Public Health, presented preliminary work that explores relationships between high-levels of air pollution exposure and health effects at a press briefing hosted by the American Association for the Advancement of Science in Boston.
New Computational Model Demonstrates How Disease Spreads In A Highly Connected World
http://mnt.to/a/4bQB
In a world of increasing global connections, predicting the spread of infectious diseases is more complicated than ever. Pandemics no longer follow the patterns they did centuries ago, when diseases swept through populations town by town; instead, they spread quickly and seemingly at random, spurred by the interactions of 3 billion air travelers per year.
A New Way Of Looking At Drug Discovery
http://mnt.to/a/4bQx
Garret FitzGerald, MD, FRS, chair of the Department of Pharmacology and Director of the Institute for Translational Medicine & Therapeutics, Perelman School of Medicine at the University of Pennsylvania, has long said the current drug-development system in the United States is in need of change, "representing an unsustainable model.
Taking A New Look At An Urban Area's Access To Healthier Foods
http://mnt.to/a/4bQs
University of Cincinnati-led research takes a new direction in examining the availability of healthy foods for urban populations by examining the commuting patterns of its residents. This new approach to identifying so-called food deserts, now published online, will appear in the May journal of Health and Place.
Hospitals May Be Unfairly Punished For High Readmission Rates
http://mnt.to/a/4bQk
When hospital patients have to be readmitted soon after discharge, hospitals look bad.A high readmission rate also can result in reduced Medicare reimbursements. But a study of spine surgery patients has found that the standard method used to calculate readmission rates is a misleading indicator of hospital quality.
Negative Obesity Coverage In Black Newspapers Could Discourage African-American Community From Taking Action
http://mnt.to/a/4bPX
Obesity rates have increased dramatically in the last few decades. According to the U.S. Census Bureau, while African Americans are only 13 percent of the total population, 82 percent of black women are overweight or obese compared to nearly 60 percent of white women, and more than 70 percent of black males are classified as overweight or obese.
Emotional Response From Billboards Can Affect Our Driving Abilities
http://mnt.to/a/4bPV
There's a billboard up ahead, a roadside sign full of language and imagery. Next stop: the emotionally distracted zone.One University of Alberta researcher has discovered that language used on billboards can provoke an emotional response that affects our driving abilities.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
Novartis Drug Zortress® Is First In Over A Decade Approved By FDA To Prevent Organ Rejection In Adult Liver Transplant Patients
http://mnt.to/a/4bRL
Zortress is the first mTOR inhibitor approved to prevent organ rejection in adult liver transplant patients in the US, where it is already approved for kidney transplantation. Under trade name Certican®, the drug was approved by European Health Authorities for use in adult liver transplant patients in the fourth quarter of 2012.
U.S. FDA Approval Of Aorfix™
http://mnt.to/a/4bRw
Lombard Medical Technologies PLC (AIM: LMT), the specialist medical technology company focused on innovative vascular products, has announced that Aorfix™ has been approved for commercial sale in the U.
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** RESPIRATORY / ASTHMA News **
Association Found Between Length Of Biological Marker And Development Of Respiratory Infection In Healthy Adults
http://mnt.to/a/4bRq
Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.
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** SENIORS / AGING News **
Physical Activity Really Does Enhance Cognition
http://mnt.to/a/4bQC
Exercise doesn't only strengthen your heart and muscles - it also beefs up your brain. Dozens of studies now show that aerobic exercise can increase the size of critical brain structures and improve cognition in children and older adults.
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** SMOKING / QUIT SMOKING News **
Potential New Therapeutic Target For Treating Non-Small Cell Lung Cancer
http://mnt.to/a/4bQP
Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response.
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** SPORTS MEDICINE / FITNESS News **
Physical Activity Really Does Enhance Cognition
http://mnt.to/a/4bQC
Exercise doesn't only strengthen your heart and muscles - it also beefs up your brain. Dozens of studies now show that aerobic exercise can increase the size of critical brain structures and improve cognition in children and older adults.
Long-Term Follow-Up Essential For Players Who Have Suffered Concussions
http://mnt.to/a/4bQw
As the National Football League braces for lawsuits by 4000 former players alleging the league failed to protect them from the long-term consequences of concussions, game-changing research by a leading Canadian researcher shows damage to the brain can persist for decades after the original head trauma.
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** STROKE News **
St. Jude Medical Initiates Landmark Study Of Renal Denervation For Reduction Of Heart Attack, Stroke And Death
http://mnt.to/a/4bRH
EnligHTNment trial will evaluate whether patients with hypertension that are treated with renal denervation and medication experience additional benefits beyond a reduction in blood pressureSt.
New Frontiers In Trauma And Stroke Recovery: Teaching The Brain To Speak Again
http://mnt.to/a/4bQz
Cynthia Thompson, a world-renowned researcher on stroke and brain damage, discussed her groundbreaking research on aphasia and the neurolinguistic systems it affects at the annual meeting of the American Association for the Advancement of Science (AAAS).
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** TRANSPLANTS / ORGAN DONATIONS News **
Novartis Drug Zortress® Is First In Over A Decade Approved By FDA To Prevent Organ Rejection In Adult Liver Transplant Patients
http://mnt.to/a/4bRL
Zortress is the first mTOR inhibitor approved to prevent organ rejection in adult liver transplant patients in the US, where it is already approved for kidney transplantation. Under trade name Certican®, the drug was approved by European Health Authorities for use in adult liver transplant patients in the fourth quarter of 2012.
----------------------------------------------
** UROLOGY / NEPHROLOGY News **
Intravenous Fluid Used To Increase Blood Volume In Critically Ill Patients Associated With Increased Risk Of Death, Kidney Injury
http://mnt.to/a/4bRn
In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous use of the fluid hydroxyethyl starch, compared with other resuscitation solutions, was not associated with decreased mortality, according to an article appearing in the February 20 issue of JAMA.
----------------------------------------------
** VASCULAR News **
U.S. FDA Approval Of Aorfix™
http://mnt.to/a/4bRw
Lombard Medical Technologies PLC (AIM: LMT), the specialist medical technology company focused on innovative vascular products, has announced that Aorfix™ has been approved for commercial sale in the U.
Viewpoints, February 20 Issue Of JAMA - US Health Care, Access & Reimbursement Policy And Atherosclerotic Renal Artery Stenosis Treatment
http://mnt.to/a/4bRs
Reengineering U.S. Health CareAri Hoffman, M.D., of the University of California, San Francisco, and Ezekiel J. Emanuel, M.D., Ph.D., of the University of Pennsylvania, Philadelphia, write that "health reform requires fixing a chronically dysfunctional system.
----------------------------------------------
** VETERANS / EX-SERVICEMEN News **
Designer Blood Clots Could Help Injured Soldiers On The Battlefield
http://mnt.to/a/4bQS
When it comes to healing the terrible wounds of war, success may hinge on the first blood clot - the one that begins forming on the battlefield right after an injury.Researchers exploring the complex stream of cellular signals produced by the body in response to a traumatic injury believe the initial response - formation of a blood clot - may control subsequent healing.
----------------------------------------------
** VETERINARY News **
In Both Humans And Dogs, The Same Genetic Defect Causes Pompe Disease
http://mnt.to/a/4bQj
Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans.
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** WATER - AIR QUALITY / AGRICULTURE News **
Analysis Links Ozone Levels, Cardiac Arrest
http://mnt.to/a/4bQK
Researchers at Rice University in Houston have found a direct correlation between out-of-hospital cardiac arrests and levels of air pollution and ozone. Their work has prompted more CPR training in at-risk communities.
Associations Explored Between Air Pollution And Health Outcomes
http://mnt.to/a/4bQJ
Lance Waller, PhD, chair of Biostatistics and Bioinformatics at Emory's Rollins School of Public Health, presented preliminary work that explores relationships between high-levels of air pollution exposure and health effects at a press briefing hosted by the American Association for the Advancement of Science in Boston.
Giving Equal Rights To Women Could Be Solution To Worldwide Food Insecurity
http://mnt.to/a/4bQh
Around the world, at least a billion people are hungry or need better diets. To feed a global population projected to reach 9.6 billion by 2050, we will need to increase food production by as much as 70 percent, most analysts believe.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Increase Seen In Use Of Robotically-Assisted Hysterectomy For Benign Gynecologic Disorders
http://mnt.to/a/4bRp
Between 2007 and 2010, the use of robotically-assisted hysterectomy for benign gynecologic disorders increased substantially, although, when compared with laparoscopic hysterectomy, the robotic procedure appears to offer little short-term benefit and is accompanied by significantly greater costs, according to a study appearing in the February 20 issue of JAMA.
Hip Implant Failure More Likely In Women
http://mnt.to/a/4bRh
A new study of 35,000 US patients, one of the largest of its kind, suggests while the risk of total hip implant failure is low, it is slightly higher in women than in men. It has prompted calls for studies to investigate which types of implants are more likely to succeed in women than men.
Giving Equal Rights To Women Could Be Solution To Worldwide Food Insecurity
http://mnt.to/a/4bQh
Around the world, at least a billion people are hungry or need better diets. To feed a global population projected to reach 9.6 billion by 2050, we will need to increase food production by as much as 70 percent, most analysts believe.
Women's Social Activism May Be Inhibited By Self-Objectification
http://mnt.to/a/4bPT
Women who live in a culture in which they are objectified by others may in turn begin to objectify themselves. This kind of self-objectification may reduce women's involvement in social activism, according to new research published in Psychological Science, a journal of the Association for Psychological Science.
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