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** ALLERGY News **
Prebiotics: Do Supplements In Baby Formula Help Prevent Allergies?
http://mnt.to/a/4cBF
Prebiotic supplements in infant formula may help to prevent eczema, according to a systematic review published in The Cochrane Library. However, the review highlights a lack of high quality evidence for the effects of prebiotics in preventing allergies.
Review Article Examines Sublingual Immunotherapy For Treatment Of Allergic Rhinitis And Asthma
http://mnt.to/a/4cBv
In an examination of a type of treatment for allergic rhinitis and asthma that is used in Europe but not approved by the U.S. Food and Drug Administration, researchers found moderate strength in the evidence from previous studies to support the use of sublingual immunotherapy for the treatment of these conditions, according to an article in the March 27 issue of JAMA.
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** ANXIETY / STRESS News **
Mugging Victims Suffer Paranoia For Months After Attack
http://mnt.to/a/4czJ
Being mugged or randomly attacked in the street often leaves people paranoid and distrustful of others long after the attack, according to a study just published. The research highlights a previously under-recognised consequence of physical assault which will help to inform therapy for those seeking help.
Brain Origins Of Variation In Pathological Anxiety Discovered
http://mnt.to/a/4cz9
New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety.
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** AUTISM News **
Genetic Connections Identified In 15q Duplication Syndrome/Autism
http://mnt.to/a/4czK
A new study published in the March issue of Autism Research from the University of Tennessee Health Science Center and Le Bonheur researchers is making the genetic connections between autism and Chromosome 15q Duplication Syndrome (Dup15q).
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** BIOLOGY / BIOCHEMISTRY News **
Valuable Organism Discovered Which Will Enable Researchers To Investigate Important Biological Questions
http://mnt.to/a/4czx
It's been more than fifty years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined; now they do.
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** BLOOD / HEMATOLOGY News **
New Method Developed To Expand Blood Stem Cells For Bone Marrow Transplant
http://mnt.to/a/4cBq
Research Shows Fewer Donor Cells May Be Needed for Transplantation and Bone Marrow Banking May Be PossibleMore than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.
Portable White Blood Cell Counter Needs Just A Pinprick Of Blood And Takes Just Minutes
http://mnt.to/a/4czH
White blood cells, or leukocytes, are the immune system's warriors. So when an infection or disease attacks the body, the system typically responds by sending more white blood cells into the fray.
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** BONES / ORTHOPEDICS News **
BioSpecifics Technologies Corp. Announces Positive Top-Line Data From XIAFLEX® Phase IIa Study For Frozen Shoulder
http://mnt.to/a/4cBJ
BioSpecifics Technologies Corp. (NASDAQ: BSTC), a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX® in the U.S., has announced positive, statistically significant top-line data from the Phase IIa study of XIAFLEX for the potential treatment of frozen shoulder (adhesive capsulitis).
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** BREAST CANCER News **
Scientists Identify Genetic Causes For Prostate, Breast And Ovarian Cancer In Breakthrough Research
http://mnt.to/a/4cBS
More than 80 genome regions that can raise a person's risk of developing prostate, breast and ovarian cancers, have been identified in a huge study led by scientists from the University of Cambridge and The Institute of Cancer Research, London.
New Compounds That Dynamically Alter Cell Signaling And Expand Options For Developing Breast Cancer Treatments
http://mnt.to/a/4czB
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.
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** CANCER / ONCOLOGY News **
Scientists Identify Genetic Causes For Prostate, Breast And Ovarian Cancer In Breakthrough Research
http://mnt.to/a/4cBS
More than 80 genome regions that can raise a person's risk of developing prostate, breast and ovarian cancers, have been identified in a huge study led by scientists from the University of Cambridge and The Institute of Cancer Research, London.
By 2022 There Will Be Nearly 18 Million Cancer Survivors In The US
http://mnt.to/a/4cBR
An aging population combined with better treatment techniques means more people will overcome cancer.The second Annual Report on Cancer Survivorship was released yesterday from the American Association for Cancer Research (AACR) and is published in the journal Cancer Epidemiology, Biomarkers & Prevention.
Hospital Remains Most Common Place Of Death For Cancer Patients In England
http://mnt.to/a/4cBy
In England, hospital is still the most common place for patients with cancer to die but an increase in home and hospice deaths since 2005 suggests that the National End of Life Care Programme (a Programme to promote the rollout of national end-of-life care initiatives) has helped more people to die at their preferred place of death, according to a UK study funded by the National Institute for Health Research Health Services and Delivery Research (NIHR HS&DR) Programme, published in this week's PLOS Medicine.
Genomic, Molecular Findings Help To Customize Personalized Medicine For Pediatric Brain Tumors
http://mnt.to/a/4czR
Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child's tumor.
Online Dietary Recommendations For Cancer Patients Inconsistent
http://mnt.to/a/4czL
Radiation oncologists at Thomas Jefferson University Hospital are stressing the need for evidence-based, standardized guidelines on dietary recommendations for cancer patients - and with good reason.
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** CARDIOVASCULAR / CARDIOLOGY News **
Chelation Therapy Still Not Proven To Work
http://mnt.to/a/4cD6
Nearly a decade ago, the National Institutes of Health began a study to determine whether patients with heart disease could be treated with chelation therapy, a controversial method that has been used by 110,000 Americans each year.
Chelation Therapy May Result In Small Reduction Of Risk Of Cardiovascular Events, But Findings Do Not Support Routine Clinical Use
http://mnt.to/a/4cBs
Although chelation therapy with the drug disodium EDTA has been used for many years with limited evidence of efficacy for the treatment of coronary disease, a randomized trial that included patients with a prior heart attack found that use of a chelation regimen modestly reduced the risk of a composite of adverse cardiovascular outcomes, but the findings do not support the routine use of chelation therapy for treatment of patients who have had a heart attack, according to a study in the March 27 issue of JAMA.
Research Findings Contribute To Understanding Malformations Of The Heart
http://mnt.to/a/4czD
Viewed from the outside, our body looks completely symmetrical. However, most internal organs - including the heart - are formed asymmetrically. The right side of the heart is responsible for pulmonary circulation; the left side supplies the rest of the body.
Potential Therapeutic Treatment For Restoring Heart Function Following Heart Attack
http://mnt.to/a/4czk
In an animal study, researchers at the University of Washington show that it was possible to use gene therapy to boost heart muscle function. The finding suggests that it might be possible to use this approach to treat patients whose hearts have been weakened by heart attacks and other heart conditions.
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** CERVICAL CANCER / HPV VACCINE News **
Cervical Cancer: DNA-Based Test More Accurate Than Repeat Smear ("Pap")
http://mnt.to/a/4cBD
In women who have a potentially or mildly abnormal cervical smear, using a DNA-based test can identify those at higher risk of having precursors of cervical cancer, according to a new Cochrane systematic review.
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** DEPRESSION News **
Depression Can Rob Us Of The Full Benefits Of Healthy Behaviors
http://mnt.to/a/4czW
Depression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine.The finding - based on measurements of the cardio-metabolic risk marker C-reactive protein (CRP) - points to another potential danger of depression, which afflicts an estimated one in 10 adults in the United States.
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** DERMATOLOGY News **
Association Between Early-Onset Baldness In African-American Men And Prostate Cancer
http://mnt.to/a/4czy
Baldness was associated with an increased risk of prostate cancer among African-American men, and risk for advanced prostate cancer increased with younger age and type of baldness, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
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** DIABETES News **
European Medicines Agency Investigates Findings On Pancreatic Risks With GLP-1-based Therapies For Type 2 Diabetes
http://mnt.to/a/4cBK
The European Medicines Agency is investigating findings by a group of independent academic researchers that suggest an increased risk of pancreatitis (inflammation of the pancreas) and pre-cancerous cellular changes called pancreatic duct metaplasia in patients with type 2 diabetes treated with so-called GLP-1-based therapies (glucagon-like peptide 1 (GLP-1) agonists and dipeptidylpeptidase-4 (DPP-4) inhibitors).
Pitt, Mount Sinai Team Finds Novel Mechanism Regulating Replication Of Insulin-Producing Beta Cells For Diabetes Treatment
http://mnt.to/a/4cBH
Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas.
Diabetes: Computer Based Interventions Provide Limited Support
http://mnt.to/a/4cBG
Self-management interventions delivered by computer and mobile phone currently provide limited benefits for people with diabetes, according to a systematic review published in The Cochrane Library.
Discovery Of Novel Mechanism Regulating Replication Of Insulin-Producing Beta Cells For Diabetes Treatment
http://mnt.to/a/4czY
Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas.
Decreasing Diabetes Risk In Obese Children And Adolescents Through Vitamin D Supplementation
http://mnt.to/a/4czX
Childhood and adolescent obesity rates in the United States have increased dramatically in the past three decades. Being obese puts individuals at greater risk for developing Type 2 diabetes, a disease in which individuals have too much sugar in their blood.
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** ENDOCRINOLOGY News **
Breath Test Reveals Gut Bacteria Linked To Obesity
http://mnt.to/a/4cBN
A growing body of evidence is increasingly showing us that the microbes in our gut influence our metabolism in surprising ways. Now a new study from the US suggests that a breath test of the gases they give out may indicate how susceptible a person is to developing obesity.
New Compounds That Dynamically Alter Cell Signaling And Expand Options For Developing Breast Cancer Treatments
http://mnt.to/a/4czB
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.
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** FLU / COLD / SARS News **
Novel Coronavirus - UAE Man Dies in Germany
http://mnt.to/a/4cD7
A 73-year-old man from the United Arab Emirates who had been transferred to Germany by air ambulance for treatment for novel coronavirus (NCoV) infection died on March 26th.The patient had been treated in intensive care at The Robert Koch Institute, Munich, Germany.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Part Of Gastric Bypass Benefit Could Be Change In Gut Microbes
http://mnt.to/a/4cC3
A new study suggests some of the weight loss that patients experience after gastric bypass surgery could be a result of changes in the mix of microbes in their gut. The researchers say manipulating microbe populations may offer an alternative treatment for obesity, for instance for patients who can't have gastric surgery.
Breath Test Reveals Gut Bacteria Linked To Obesity
http://mnt.to/a/4cBN
A growing body of evidence is increasingly showing us that the microbes in our gut influence our metabolism in surprising ways. Now a new study from the US suggests that a breath test of the gases they give out may indicate how susceptible a person is to developing obesity.
Climate Change Driving Diarrheal Disease
http://mnt.to/a/4czS
In a National Science Foundation funded study, Kathleen Alexander, an associate professor of wildlife at Virginia Tech, found that climate drives a large part of diarrheal disease and increases the threat of climate change for vulnerable communities.
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** GENETICS News **
Study Suggests Teenage Smokers With Higher Genetic Risk Associated With Development Of Adult Smoking Problems
http://mnt.to/a/4cCN
JAMA Psychiatry Study HighlightsA study by Daniel W. Belsky, Ph.D., of the University of North Carolina at Chapel Hill and Duke University Medical Center, Durham, North Carolina, and colleagues sought to examine how genetic risks influence the developmental progression of smoking behavior from initiation through conversion to daily smoking, progression to heavy smoking, nicotine dependence, and struggles with quitting.
Cervical Cancer: DNA-Based Test More Accurate Than Repeat Smear ("Pap")
http://mnt.to/a/4cBD
In women who have a potentially or mildly abnormal cervical smear, using a DNA-based test can identify those at higher risk of having precursors of cervical cancer, according to a new Cochrane systematic review.
The Economics Of Genomic Medicine - Insights From The IOM Roundtable On Translating Genomic-Based Research For Health
http://mnt.to/a/4cBw
Viewpoint in This Issue of JAMAIn this Viewpoint, W. Gregory Feero, M.D., Ph.D., of the Maine-Dartmouth Family Medicine Residency, Augusta, Maine (Dr. Feero is also Contributing Editor, JAMA), and colleagues discuss several of the issues that became apparent from the July 2012 Institute of Medicine's (IOM's) Roundtable on Translating Genomic-Based Research for Health, a meeting designed to identify critical gaps unique to understanding the economics of adopting whole-genome or exome sequence information into health care.
Mouse Model To Study Vocal Learning, Learn About Genetic Mechanism Behind Communications Disorders
http://mnt.to/a/4czV
Scientists have long thought that mice might serve as a model for how humans learn to vocalize. But new research led by scientists at Washington State University-Vancouver has found that, unlike humans and songbirds, mice do not learn how to vocalize.
Genomic, Molecular Findings Help To Customize Personalized Medicine For Pediatric Brain Tumors
http://mnt.to/a/4czR
Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child's tumor.
Childhood Body Weight Strongly Influenced By Genes
http://mnt.to/a/4czN
Previous research has shown that obesity runs in families, and twin studies suggest that this is largely due to genetic factors, with heritability estimates over 50%. 32 genes have been identified as risk factors for obesity but previous analyses suggest that these genes alone cannot fully explain the high level of heritability in childhood obesity, as together they explain only 2% of individual differences in childhood body weight.
Genetic Connections Identified In 15q Duplication Syndrome/Autism
http://mnt.to/a/4czK
A new study published in the March issue of Autism Research from the University of Tennessee Health Science Center and Le Bonheur researchers is making the genetic connections between autism and Chromosome 15q Duplication Syndrome (Dup15q).
New Nerve Cells Formed Directly In The Brain
http://mnt.to/a/4czF
The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in Sweden shows that it is possible to re-programme other cells to become nerve cells, directly in the brain.
Valuable Organism Discovered Which Will Enable Researchers To Investigate Important Biological Questions
http://mnt.to/a/4czx
It's been more than fifty years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined; now they do.
Potential Therapeutic Treatment For Restoring Heart Function Following Heart Attack
http://mnt.to/a/4czk
In an animal study, researchers at the University of Washington show that it was possible to use gene therapy to boost heart muscle function. The finding suggests that it might be possible to use this approach to treat patients whose hearts have been weakened by heart attacks and other heart conditions.
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** HEADACHE / MIGRAINE News **
Migraine Patients Have Brain Abnormalities Which Can Be Demonstrated Using MRI
http://mnt.to/a/4czb
A new study suggests that migraines are related to brain abnormalities present at birth and others that develop over time. The research is published online in the journal Radiology.Migraines are intense, throbbing headaches, sometimes accompanied by nausea, vomiting and sensitivity to light.
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** HEART DISEASE News **
Chelation Therapy Still Not Proven To Work
http://mnt.to/a/4cD6
Nearly a decade ago, the National Institutes of Health began a study to determine whether patients with heart disease could be treated with chelation therapy, a controversial method that has been used by 110,000 Americans each year.
Unprecedented Efficacy Shown By Potential Chagas Vaccine Candidate
http://mnt.to/a/4czG
Scientists are getting closer to a Chagas disease vaccine, something many believed impossible only 10 years ago. Research from the Sealy Center for Vaccine Development at the University of Texas Medical Branch at Galveston has resulted in a safe vaccine candidate that is simple to produce and shows a greater than 90 percent protection rate against chronic infection in mice.
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** HIV / AIDS News **
The Importance Of Sexual Agreements Among Gay Couples
http://mnt.to/a/4czT
The majority of gay men in relationships say they establish a "sexual agreement" with their partner, primarily to prevent the spread of HIV and other sexually transmitted diseases, according to a University of Michigan study.
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** IMMUNE SYSTEM / VACCINES News **
New Vaccine For Foot And Mouth Safer, Cheaper To Make Thanks To Synthetic Virus Shell
http://mnt.to/a/4cD3
UK scientists have developed a new vaccine against foot and mouth disease that is cheaper and safer to manufacture thanks to the fact it doesn't rely on inactivating live infectious virus but uses a synthetic virus shell to provoke an immune response.
Depression Can Rob Us Of The Full Benefits Of Healthy Behaviors
http://mnt.to/a/4czW
Depression may inhibit the anti-inflammatory effects typically associated with physical activity and light-to-moderate alcohol consumption, according to researchers at Duke Medicine.The finding - based on measurements of the cardio-metabolic risk marker C-reactive protein (CRP) - points to another potential danger of depression, which afflicts an estimated one in 10 adults in the United States.
Unprecedented Efficacy Shown By Potential Chagas Vaccine Candidate
http://mnt.to/a/4czG
Scientists are getting closer to a Chagas disease vaccine, something many believed impossible only 10 years ago. Research from the Sealy Center for Vaccine Development at the University of Texas Medical Branch at Galveston has resulted in a safe vaccine candidate that is simple to produce and shows a greater than 90 percent protection rate against chronic infection in mice.
New Compounds That Dynamically Alter Cell Signaling And Expand Options For Developing Breast Cancer Treatments
http://mnt.to/a/4czB
Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.
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** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Novel Coronavirus - UAE Man Dies in Germany
http://mnt.to/a/4cD7
A 73-year-old man from the United Arab Emirates who had been transferred to Germany by air ambulance for treatment for novel coronavirus (NCoV) infection died on March 26th.The patient had been treated in intensive care at The Robert Koch Institute, Munich, Germany.
New Vaccine For Foot And Mouth Safer, Cheaper To Make Thanks To Synthetic Virus Shell
http://mnt.to/a/4cD3
UK scientists have developed a new vaccine against foot and mouth disease that is cheaper and safer to manufacture thanks to the fact it doesn't rely on inactivating live infectious virus but uses a synthetic virus shell to provoke an immune response.
Study Reveals How Bacterial Resistance Works
http://mnt.to/a/4cBP
Researchers from Tufts University School of Medicine have identified an isolate of E. coli which is resistant to the class of antibiotics carbapenems - used to treat life threatening disease-causing bacteria.
Certain Antibiotics May Provide Benefit For Treatment Of Respiratory Disorder, Although Increase Risk Of Antibiotic Resistance
http://mnt.to/a/4cBt
Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin or erythromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to two studies appearing in the March 27 issue of JAMA.
Climate Change Driving Diarrheal Disease
http://mnt.to/a/4czS
In a National Science Foundation funded study, Kathleen Alexander, an associate professor of wildlife at Virginia Tech, found that climate drives a large part of diarrheal disease and increases the threat of climate change for vulnerable communities.
Portable White Blood Cell Counter Needs Just A Pinprick Of Blood And Takes Just Minutes
http://mnt.to/a/4czH
White blood cells, or leukocytes, are the immune system's warriors. So when an infection or disease attacks the body, the system typically responds by sending more white blood cells into the fray.
Inhibiting Akt May Be A Useful Therapeutic Strategy For Stopping Herpes Infections
http://mnt.to/a/4cz6
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1).
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** IT / INTERNET / E-MAIL News **
Editors Call For A Fully Correctable Research Literature
http://mnt.to/a/4cBB
Many scientific findings, once thought to be certain, will ultimately be shown to be uncertain by new techniques, a change in thinking, improved data, research misconduct, or the result of an honest error.
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** LITIGATION / MEDICAL MALPRACTICE News **
Research Misconduct Is A Global Problem
http://mnt.to/a/4cBC
Research activity is global, therefore, research misconduct is a global problem. These are the conclusions of two commissioned Essays this week in PLOS Medicine that review the problem of research misconduct across the world and provide a landscape review of the policies and initiatives of government and institutions to manage research misconduct.
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** LUNG CANCER News **
Patients With ALK--Positive Non-Small Cell Lung Cancer Benefit From Ganetespib
http://mnt.to/a/4czz
A drug that indirectly impairs the function of several cancer-driving proteins, including anaplastic lymphoma kinase (ALK), may be an effective new treatment for patients with ALK--positive non-small cell lung cancer.
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** MEDICAL DEVICES / DIAGNOSTICS News **
Portable White Blood Cell Counter Needs Just A Pinprick Of Blood And Takes Just Minutes
http://mnt.to/a/4czH
White blood cells, or leukocytes, are the immune system's warriors. So when an infection or disease attacks the body, the system typically responds by sending more white blood cells into the fray.
----------------------------------------------
** MEN'S HEALTH News **
The Importance Of Sexual Agreements Among Gay Couples
http://mnt.to/a/4czT
The majority of gay men in relationships say they establish a "sexual agreement" with their partner, primarily to prevent the spread of HIV and other sexually transmitted diseases, according to a University of Michigan study.
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** MENOPAUSE News **
Some Women Over 40 Under The Misapprehension That Contraception Is Unnecessary
http://mnt.to/a/4czh
Women reaching the age of 40 tend to be less vigilant about birth control because they think the risk of pregnancy is low - or that birth control can cause health problems - but a review of the evidence by a team that includes a Women & Infants Hospital of Rhode Island physician recently underscored the need to be vigilant about contraception even in perimenopause.
Formula May Pinpoint Timing Of Final Menstrual Period, Help Menopausal Women Combat Bone Loss, Cardiovascular Risk
http://mnt.to/a/4czd
For women enduring hot flashes and other symptoms of menopause, a new model could better estimate the timing of the final menstrual period, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
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** MENTAL HEALTH News **
Compulsory Community Treatment For Mentally Ill Patients Does Not Reduce Rates Of Hospitalisation
http://mnt.to/a/4cBx
The controversial practice of discharging people under Community Treatment Orders (CTOs) after they have been involuntarily hospitalised due to mental health problems has no effect on the patients' likelihood of being subsequently hospitalised, compared to Section 17 leave, an older and less restrictive type of supervised discharge, according to a randomised trial published Online First in The Lancet.
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** MULTIPLE SCLEROSIS News **
Tecfidera Approved For Multiple Sclerosis By FDA
http://mnt.to/a/4cD5
Tecfidera (dimethyl fumarate) capsules have just been approved by the U.S. Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis (MS).MS is an autoimmune disease of the central nervous system that is known for being persistent and inflammatory.
Effect Of Genzyme's LEMTRADA Maintained In Patients Beyond Two-Year Pivotal MS Studies
http://mnt.to/a/4cBr
In more than 70 percent of patients, disability scores improved or remained stable over three yearsGenzyme, a Sanofi Company (EURONEXT: SAN and NYSE: SNY), have announced interim results from the first year of the extension study of LEMTRADA™ (alemtuzumab), being developed for the treatment for multiple sclerosis (MS).
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** NEUROLOGY / NEUROSCIENCE News **
Brain Scans Can Predict Criminal Behavior
http://mnt.to/a/4cBQ
Brain scans can predict whether convicted felons are likely to engage in criminal behavior in the future, according to neuroscientists.The experts, from the Mind Research Network in New Mexico, conducted research involving nearly 100 male prisoners who were given a functional MRI (magnetic resonance imaging) scan at the time of their release.
Mouse Model To Study Vocal Learning, Learn About Genetic Mechanism Behind Communications Disorders
http://mnt.to/a/4czV
Scientists have long thought that mice might serve as a model for how humans learn to vocalize. But new research led by scientists at Washington State University-Vancouver has found that, unlike humans and songbirds, mice do not learn how to vocalize.
New Nerve Cells Formed Directly In The Brain
http://mnt.to/a/4czF
The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in Sweden shows that it is possible to re-programme other cells to become nerve cells, directly in the brain.
Unruptured Intracranial Arteriovenous Malformations Treated With Radiosurgery
http://mnt.to/a/4czw
Researchers at the University of Virginia (UVA) Health System recommend radiosurgery for treating unruptured arteriovenous malformations (AVMs), because the procedure has a reasonable benefit-to-risk profile.
Biologists Pinpoint The Origin Of Olfactory Nerve Cells
http://mnt.to/a/4cz5
When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone. These sensory neurons are particularly interesting because they are the only neurons in our bodies that regenerate throughout adult life - as some of our olfactory neurons die, they are soon replaced by newborns.
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** NUTRITION / DIET News **
Part Of Gastric Bypass Benefit Could Be Change In Gut Microbes
http://mnt.to/a/4cC3
A new study suggests some of the weight loss that patients experience after gastric bypass surgery could be a result of changes in the mix of microbes in their gut. The researchers say manipulating microbe populations may offer an alternative treatment for obesity, for instance for patients who can't have gastric surgery.
Decreasing Diabetes Risk In Obese Children And Adolescents Through Vitamin D Supplementation
http://mnt.to/a/4czX
Childhood and adolescent obesity rates in the United States have increased dramatically in the past three decades. Being obese puts individuals at greater risk for developing Type 2 diabetes, a disease in which individuals have too much sugar in their blood.
Online Dietary Recommendations For Cancer Patients Inconsistent
http://mnt.to/a/4czL
Radiation oncologists at Thomas Jefferson University Hospital are stressing the need for evidence-based, standardized guidelines on dietary recommendations for cancer patients - and with good reason.
Vitamin D Supports Lung Function As Well As Bone Health
http://mnt.to/a/4czc
Maintaining adequate levels of vitamin D can help people breathe better and may even protect against tuberculosis (TB), according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
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** OBESITY / WEIGHT LOSS / FITNESS News **
Part Of Gastric Bypass Benefit Could Be Change In Gut Microbes
http://mnt.to/a/4cC3
A new study suggests some of the weight loss that patients experience after gastric bypass surgery could be a result of changes in the mix of microbes in their gut. The researchers say manipulating microbe populations may offer an alternative treatment for obesity, for instance for patients who can't have gastric surgery.
Breath Test Reveals Gut Bacteria Linked To Obesity
http://mnt.to/a/4cBN
A growing body of evidence is increasingly showing us that the microbes in our gut influence our metabolism in surprising ways. Now a new study from the US suggests that a breath test of the gases they give out may indicate how susceptible a person is to developing obesity.
Decreasing Diabetes Risk In Obese Children And Adolescents Through Vitamin D Supplementation
http://mnt.to/a/4czX
Childhood and adolescent obesity rates in the United States have increased dramatically in the past three decades. Being obese puts individuals at greater risk for developing Type 2 diabetes, a disease in which individuals have too much sugar in their blood.
Increased Risk Of Adverse Neonatal And Maternal Outcomes In Overweight And Obese Women
http://mnt.to/a/4czP
Overweight and obese women are more likely to require specialist medical care during their pregnancy due to the increased risk of adverse neonatal and maternal outcomes, finds a new study published in BJOG: An International Journal of Obstetrics and Gynaecology.
Childhood Body Weight Strongly Influenced By Genes
http://mnt.to/a/4czN
Previous research has shown that obesity runs in families, and twin studies suggest that this is largely due to genetic factors, with heritability estimates over 50%. 32 genes have been identified as risk factors for obesity but previous analyses suggest that these genes alone cannot fully explain the high level of heritability in childhood obesity, as together they explain only 2% of individual differences in childhood body weight.
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** PARKINSON'S DISEASE News **
New Nerve Cells Formed Directly In The Brain
http://mnt.to/a/4czF
The field of cell therapy, which aims to form new cells in the body in order to cure disease, has taken another important step in the development towards new treatments. A new report from researchers at Lund University in Sweden shows that it is possible to re-programme other cells to become nerve cells, directly in the brain.
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** PEDIATRICS / CHILDREN'S HEALTH News **
Study Suggests Teenage Smokers With Higher Genetic Risk Associated With Development Of Adult Smoking Problems
http://mnt.to/a/4cCN
JAMA Psychiatry Study HighlightsA study by Daniel W. Belsky, Ph.D., of the University of North Carolina at Chapel Hill and Duke University Medical Center, Durham, North Carolina, and colleagues sought to examine how genetic risks influence the developmental progression of smoking behavior from initiation through conversion to daily smoking, progression to heavy smoking, nicotine dependence, and struggles with quitting.
Prebiotics: Do Supplements In Baby Formula Help Prevent Allergies?
http://mnt.to/a/4cBF
Prebiotic supplements in infant formula may help to prevent eczema, according to a systematic review published in The Cochrane Library. However, the review highlights a lack of high quality evidence for the effects of prebiotics in preventing allergies.
Death In Young Children Linked To Their Mother's Poor Health
http://mnt.to/a/4cBz
In poorer countries, young children are more likely to die in the months before their mother's death, when she is seriously ill, and also in the period after her death, according to a study by international researchers published in this week's PLOS Medicine.
Climate Change Driving Diarrheal Disease
http://mnt.to/a/4czS
In a National Science Foundation funded study, Kathleen Alexander, an associate professor of wildlife at Virginia Tech, found that climate drives a large part of diarrheal disease and increases the threat of climate change for vulnerable communities.
Genomic, Molecular Findings Help To Customize Personalized Medicine For Pediatric Brain Tumors
http://mnt.to/a/4czR
Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child's tumor.
Childhood Body Weight Strongly Influenced By Genes
http://mnt.to/a/4czN
Previous research has shown that obesity runs in families, and twin studies suggest that this is largely due to genetic factors, with heritability estimates over 50%. 32 genes have been identified as risk factors for obesity but previous analyses suggest that these genes alone cannot fully explain the high level of heritability in childhood obesity, as together they explain only 2% of individual differences in childhood body weight.
New Research Agenda Could Help Shed Light On Early Language, Cognitive Development
http://mnt.to/a/4cz8
Researchers are digging deeper into whether infants' ability to learn new words is shaped by the particular language being acquired.A new Northwestern University study cites a promising new research agenda aimed at bringing researchers closer to discovering the impact of different languages on early language and cognitive development.
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** PREGNANCY / OBSTETRICS News **
Increased Risk Of Adverse Neonatal And Maternal Outcomes In Overweight And Obese Women
http://mnt.to/a/4czP
Overweight and obese women are more likely to require specialist medical care during their pregnancy due to the increased risk of adverse neonatal and maternal outcomes, finds a new study published in BJOG: An International Journal of Obstetrics and Gynaecology.
Maternal Sleep Position May Influence Pregnancy Outcomes
http://mnt.to/a/4cz7
Pregnant women in Ghana who slept on their back (supine sleep) were at an increased risk of stillbirth compared to women who did not sleep on their back, according to new research led by a University of Michigan researcher.
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** PROSTATE / PROSTATE CANCER News **
Scientists Identify Genetic Causes For Prostate, Breast And Ovarian Cancer In Breakthrough Research
http://mnt.to/a/4cBS
More than 80 genome regions that can raise a person's risk of developing prostate, breast and ovarian cancers, have been identified in a huge study led by scientists from the University of Cambridge and The Institute of Cancer Research, London.
Association Between Early-Onset Baldness In African-American Men And Prostate Cancer
http://mnt.to/a/4czy
Baldness was associated with an increased risk of prostate cancer among African-American men, and risk for advanced prostate cancer increased with younger age and type of baldness, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
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** PSYCHOLOGY / PSYCHIATRY News **
Brain Scans Can Predict Criminal Behavior
http://mnt.to/a/4cBQ
Brain scans can predict whether convicted felons are likely to engage in criminal behavior in the future, according to neuroscientists.The experts, from the Mind Research Network in New Mexico, conducted research involving nearly 100 male prisoners who were given a functional MRI (magnetic resonance imaging) scan at the time of their release.
Mugging Victims Suffer Paranoia For Months After Attack
http://mnt.to/a/4czJ
Being mugged or randomly attacked in the street often leaves people paranoid and distrustful of others long after the attack, according to a study just published. The research highlights a previously under-recognised consequence of physical assault which will help to inform therapy for those seeking help.
Brain Origins Of Variation In Pathological Anxiety Discovered
http://mnt.to/a/4cz9
New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety.
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** PUBLIC HEALTH News **
By 2022 There Will Be Nearly 18 Million Cancer Survivors In The US
http://mnt.to/a/4cBR
An aging population combined with better treatment techniques means more people will overcome cancer.The second Annual Report on Cancer Survivorship was released yesterday from the American Association for Cancer Research (AACR) and is published in the journal Cancer Epidemiology, Biomarkers & Prevention.
If You Think Seatbelt Use Inconvenient, Consider The Inconvenience Of Being Injured, Or Worse
http://mnt.to/a/4czm
Since most driving is done locally, it should not be surprising that most auto accidents occur during local errands. Yet, occasional seatbelt users are more likely to buckle up for trips on high speed roads, according to an analysis of data from 100 instrumented vehicles reported in a recent issue of Accident Analysis and Prevention.
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** RADIOLOGY / NUCLEAR MEDICINE News **
Unruptured Intracranial Arteriovenous Malformations Treated With Radiosurgery
http://mnt.to/a/4czw
Researchers at the University of Virginia (UVA) Health System recommend radiosurgery for treating unruptured arteriovenous malformations (AVMs), because the procedure has a reasonable benefit-to-risk profile.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
Tecfidera Approved For Multiple Sclerosis By FDA
http://mnt.to/a/4cD5
Tecfidera (dimethyl fumarate) capsules have just been approved by the U.S. Food and Drug Administration (FDA) to treat adults with relapsing forms of multiple sclerosis (MS).MS is an autoimmune disease of the central nervous system that is known for being persistent and inflammatory.
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** REHABILITATION / PHYSICAL THERAPY News **
BioSpecifics Technologies Corp. Announces Positive Top-Line Data From XIAFLEX® Phase IIa Study For Frozen Shoulder
http://mnt.to/a/4cBJ
BioSpecifics Technologies Corp. (NASDAQ: BSTC), a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX® in the U.S., has announced positive, statistically significant top-line data from the Phase IIa study of XIAFLEX for the potential treatment of frozen shoulder (adhesive capsulitis).
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** RESPIRATORY / ASTHMA News **
Review Article Examines Sublingual Immunotherapy For Treatment Of Allergic Rhinitis And Asthma
http://mnt.to/a/4cBv
In an examination of a type of treatment for allergic rhinitis and asthma that is used in Europe but not approved by the U.S. Food and Drug Administration, researchers found moderate strength in the evidence from previous studies to support the use of sublingual immunotherapy for the treatment of these conditions, according to an article in the March 27 issue of JAMA.
Certain Antibiotics May Provide Benefit For Treatment Of Respiratory Disorder, Although Increase Risk Of Antibiotic Resistance
http://mnt.to/a/4cBt
Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin or erythromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to two studies appearing in the March 27 issue of JAMA.
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** SEXUAL HEALTH / STDS News **
The Importance Of Sexual Agreements Among Gay Couples
http://mnt.to/a/4czT
The majority of gay men in relationships say they establish a "sexual agreement" with their partner, primarily to prevent the spread of HIV and other sexually transmitted diseases, according to a University of Michigan study.
Some Women Over 40 Under The Misapprehension That Contraception Is Unnecessary
http://mnt.to/a/4czh
Women reaching the age of 40 tend to be less vigilant about birth control because they think the risk of pregnancy is low - or that birth control can cause health problems - but a review of the evidence by a team that includes a Women & Infants Hospital of Rhode Island physician recently underscored the need to be vigilant about contraception even in perimenopause.
Inhibiting Akt May Be A Useful Therapeutic Strategy For Stopping Herpes Infections
http://mnt.to/a/4cz6
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1).
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** SMOKING / QUIT SMOKING News **
Study Suggests Teenage Smokers With Higher Genetic Risk Associated With Development Of Adult Smoking Problems
http://mnt.to/a/4cCN
JAMA Psychiatry Study HighlightsA study by Daniel W. Belsky, Ph.D., of the University of North Carolina at Chapel Hill and Duke University Medical Center, Durham, North Carolina, and colleagues sought to examine how genetic risks influence the developmental progression of smoking behavior from initiation through conversion to daily smoking, progression to heavy smoking, nicotine dependence, and struggles with quitting.
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** SPORTS MEDICINE / FITNESS News **
BioSpecifics Technologies Corp. Announces Positive Top-Line Data From XIAFLEX® Phase IIa Study For Frozen Shoulder
http://mnt.to/a/4cBJ
BioSpecifics Technologies Corp. (NASDAQ: BSTC), a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX® in the U.S., has announced positive, statistically significant top-line data from the Phase IIa study of XIAFLEX for the potential treatment of frozen shoulder (adhesive capsulitis).
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** STEM CELL RESEARCH News **
New Method Developed To Expand Blood Stem Cells For Bone Marrow Transplant
http://mnt.to/a/4cBq
Research Shows Fewer Donor Cells May Be Needed for Transplantation and Bone Marrow Banking May Be PossibleMore than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.
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** TRANSPLANTS / ORGAN DONATIONS News **
New Method Developed To Expand Blood Stem Cells For Bone Marrow Transplant
http://mnt.to/a/4cBq
Research Shows Fewer Donor Cells May Be Needed for Transplantation and Bone Marrow Banking May Be PossibleMore than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.
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** TROPICAL DISEASES News **
Unprecedented Efficacy Shown By Potential Chagas Vaccine Candidate
http://mnt.to/a/4czG
Scientists are getting closer to a Chagas disease vaccine, something many believed impossible only 10 years ago. Research from the Sealy Center for Vaccine Development at the University of Texas Medical Branch at Galveston has resulted in a safe vaccine candidate that is simple to produce and shows a greater than 90 percent protection rate against chronic infection in mice.
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** TUBERCULOSIS News **
Vitamin D Supports Lung Function As Well As Bone Health
http://mnt.to/a/4czc
Maintaining adequate levels of vitamin D can help people breathe better and may even protect against tuberculosis (TB), according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
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** UROLOGY / NEPHROLOGY News **
Technology For Treating Wastewater Has Many Applications From Desalination To Kidney Dialysis
http://mnt.to/a/4czC
A newly developed membrane used to separate waste from water could become key in the treatment of pollutants ranging from acid mine drainage to oil-containing wastewater, as well as in processes ranging from desalination to kidney dialysis.
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** VASCULAR News **
Unruptured Intracranial Arteriovenous Malformations Treated With Radiosurgery
http://mnt.to/a/4czw
Researchers at the University of Virginia (UVA) Health System recommend radiosurgery for treating unruptured arteriovenous malformations (AVMs), because the procedure has a reasonable benefit-to-risk profile.
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** VETERINARY News **
New Vaccine For Foot And Mouth Safer, Cheaper To Make Thanks To Synthetic Virus Shell
http://mnt.to/a/4cD3
UK scientists have developed a new vaccine against foot and mouth disease that is cheaper and safer to manufacture thanks to the fact it doesn't rely on inactivating live infectious virus but uses a synthetic virus shell to provoke an immune response.
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** WATER - AIR QUALITY / AGRICULTURE News **
Technology For Treating Wastewater Has Many Applications From Desalination To Kidney Dialysis
http://mnt.to/a/4czC
A newly developed membrane used to separate waste from water could become key in the treatment of pollutants ranging from acid mine drainage to oil-containing wastewater, as well as in processes ranging from desalination to kidney dialysis.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Some Women Over 40 Under The Misapprehension That Contraception Is Unnecessary
http://mnt.to/a/4czh
Women reaching the age of 40 tend to be less vigilant about birth control because they think the risk of pregnancy is low - or that birth control can cause health problems - but a review of the evidence by a team that includes a Women & Infants Hospital of Rhode Island physician recently underscored the need to be vigilant about contraception even in perimenopause.
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