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** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **
New Figures Show UK Alcohol Consumption Down 3.3 Per Cent In 2012
http://mnt.to/a/4c8c
UK alcohol consumption per head down again - 3.3 per cent drop in 2012. 16 per cent decline in consumption per head since 2004. Per capita consumption below 8 litres per head, first time since 1998.
Global Burden Of Disease And Injury Attributable To Alcohol Is Large And Growing
http://mnt.to/a/4c7R
A new study by the Centre for Addiction and Mental Health (CAMH) shows that alcohol is now the third leading cause of the global burden of disease and injury, despite the fact most adults worldwide abstain from drinking.
Findings Of 2 Important Studies Published In AIDS Journal
http://mnt.to/a/4c7P
The results of two important studies have been published in the March issue of AIDS, the official journal of the International AIDS Society. One study notes that screening for HIV should be performed more frequently - up to every three months for the highest-risk patients, while low-risk groups to be tested every three years.
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** ANXIETY / STRESS News **
Reducing Effects Of Traumatic Events At The Molecular Level
http://mnt.to/a/4c8j
Reducing fear and stress following a traumatic event could be as simple as providing a protein synthesis blocker to the brain, report a team of researchers from McLean Hospital, Harvard Medical School, McGill University, and Massachusetts General Hospital in a paper published in the Proceedings of the National Academy of Sciences.
Support Interventions May Decrease Stress Hormone Which Foreshadows Postpartum Depression In New Mothers
http://mnt.to/a/4c8h
Women who receive strong social support from their families during pregnancy appear to be protected from sharp increases in a particular stress hormone, making them less likely to develop postpartum depression, according to a new study published in Clinical Psychological Science, a journal of the Association for Psychological Science.
New Moms Suffer More Obsessive-Compulsive Symptoms Than General Population
http://mnt.to/a/4c7t
A new mother may constantly worry and check to see if her baby is still breathing. Or she may fret about germs, obsessing whether she's properly sterilized the bottles, then wash and rewash them.
Woman's Exposure To Stress During Pregnancy Impacts Fetal Brain Via The Placenta
http://mnt.to/a/4c7r
The mammalian placenta is more than just a filter through which nutrition and oxygen are passed from a mother to her unborn child. According to a new study by a research group from the University of Pennsylvania School of Veterinary Medicine, if a mother is exposed to stress during pregnancy, her placenta translates that experience to her fetus by altering levels of a protein that affects the developing brains of male and female offspring differently.
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** AUTISM News **
Study By Kennedy Krieger's Center For Autism And Related Disorders Reveals Key Predictors Of Speech Gains
http://mnt.to/a/4c7T
New findings published in Pediatrics (Epub ahead of print) by the Kennedy Krieger Institute's Center for Autism and Related Disorders reveal that 70 percent of children with autism spectrum disorders (ASD) who have a history of severe language delay, achieved phrase or fluent speech by age eight.
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** BIPOLAR News **
New Gene Variant May Explain Psychotic Features In Bipolar Disorder
http://mnt.to/a/4c8g
Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis.
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** BREAST CANCER News **
In Late-Stage Diagnosis Of Breast Cancer, Neighborhood Poverty And Health Insurance Are Common
http://mnt.to/a/4c8v
Home may be where the heart is, but where you live could affect your health."Regardless of geographic location, women who live in high poverty areas or are uninsured are at greatest risk of being diagnosed with breast cancer at a later stage," said lead author Kevin Henry, Department of Geography, University of Utah.
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** CANCER / ONCOLOGY News **
Breath Test Could Detect And Diagnose Stomach Cancer
http://mnt.to/a/4c8V
A simple test that analyzes the chemical signature of a patient's exhaled breath could help diagnose stomach cancer, according to new research by scientists from Israel and China reported online in the British Journal of Cancer this week.
Revision Of Latest Methodologies For Studying Evolution And Interaction Of Proteins
http://mnt.to/a/4c8p
Spanish National Cancer Research Centre (CNIO) researchers Alfonso Valencia, Director of the Structural Biology and Biocomputing Programme and David de Juan, jointly with Florencio Pazos, from the Spanish National Centre for Biotechnology (CNB-CSIC), publish a review on the latest computational methods that, based on evolutionary principles, are revolutionising the field of analysis and prediction of protein structure, function and protein-protein interactions, as well as the short- and long-term expectations for the field.
Visceral Fat Causally Linked To Intestinal Cancer
http://mnt.to/a/4c87
Loss of fat by surgical removal or a calorierestricted diet reduced likelihood of developing intestinal tumors. Differences were found between male and female mice. Study emphasizes the need for strategies to reduce visceral fat.
Newly Identified Biomarkers May Help Predict Progression Of Barrett's Esophagus To Esophageal Adenocarcinoma
http://mnt.to/a/4c86
Expression of most microRNAs was similar between the two conditions. A small number were differentially expressed. These microRNAs could be biomarkers for early diagnosis of progression.A series of microRNA expression signatures that may help to define progression of the precancerous condition Barrett's esophagus into esophageal adenocarcinoma was reported recently in Cancer Prevention Research, a journal of the American Association for Cancer Research.
Enzyme's Double Life Revealed - Critical Role In Cancer Blood Supply
http://mnt.to/a/4c82
Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected - and critical - additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.
Many Children With Retinoblastoma May Safely Forego Adjuvant Chemotherapy
http://mnt.to/a/4c7G
New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether.
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** CARDIOVASCULAR / CARDIOLOGY News **
Insomnia Triples Risk of Heart Failure
http://mnt.to/a/4cbg
The risk of developing heart failure tripes for people who suffer from insomnia.The finding came from a new study, the largest yet to examine the association, and was published in the European Heart Journal.
Health Secretary Plans To Tackle UK's High Cardiovascular Disease Death Rate
http://mnt.to/a/4c8C
Health Secretary Jeremy Hunt has just announced that the UK is developing a new plan to tackle cardiovascular disease (CVD) which could save up to 30,000 lives over the next several years. The UK is behind a lot of other Western countries in managing cardiovascular diseases.
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** COLORECTAL CANCER News **
Colonoscopy May Reduce Advanced Cancer Risk By 70%
http://mnt.to/a/4c8F
Colonoscopy screening reduces the risk of advanced colorectal cancer by about 70% in average-risk adults.The finding came from a new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania and was published in the journal Annals of Internal Medicine.
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** CONFERENCES News **
3rd Annual European Life Sciences EPP Pricing & Profit Optimisation Forum: Performing "Under Pressure" 5-6 June 2013, Switzerland
http://mnt.to/a/4c9W
Life Sciences organisations in Europe are facing unprecedented challenges: a heightened competitive state is squeezing margins, whilst at the same time emerging markets bring new opportunities as well complexities that require water-tight commercial compliance, firm controls on discounts, rebates and incentives as well as highly skilled teams with a clear strategy and good insights.
Enzyme's Double Life Revealed - Critical Role In Cancer Blood Supply
http://mnt.to/a/4c82
Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected - and critical - additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.
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** DEPRESSION News **
Support Interventions May Decrease Stress Hormone Which Foreshadows Postpartum Depression In New Mothers
http://mnt.to/a/4c8h
Women who receive strong social support from their families during pregnancy appear to be protected from sharp increases in a particular stress hormone, making them less likely to develop postpartum depression, according to a new study published in Clinical Psychological Science, a journal of the Association for Psychological Science.
How The Brain Tires When Exercising Has Implications For Doping In Sport, Motor Contol, Depression
http://mnt.to/a/4c7x
A marathon runner approaches the finishing line, but suddenly the sweaty athlete collapses to the ground. Everyone probably assumes that this is because he has expended all energy in his muscles.
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** DIABETES News **
Tresiba(R) (Insulin Degludec) A New Basal Insulin For Adult Patients With Type 1 And Type 2 Diabetes Is Available In The UK
http://mnt.to/a/4c8b
Insulin degludec is indicated for the treatment of diabetes mellitus in adults[1].Novo Nordisk UK has announced that insulin degludec (brand name Tresiba(R)), a newoncedaily basal insulin for adult patients with type 1 and type 2 diabetes, is availablein the UK as a new treatment option.
Tresiba(R) (Insulin Degludec) A New Basal Insulin For Adult Patients With Type 1 And Type 2 Diabetes Is Available In The UK
http://mnt.to/a/4c89
Insulin degludec is indicated for the treatment of diabetes mellitus in adults[1].Novo Nordisk UK has announced that insulin degludec (brand name Tresiba(R)), a newoncedaily basal insulin for adult patients with type 1 and type 2 diabetes, is availablein the UK as a new treatment option.
Cognitive Behavioral Therapy Helps To Treat Diabetic Neuropathies
http://mnt.to/a/4c84
Researchers at Boston University School of Medicine (BUSM) and VA Boston Healthcare System (VA BHS) have found that cognitive behavioral therapy (CBT) can help relieve pain for people with painful diabetic neuropathies.
Patients Benefit From Quality Of Care Measures
http://mnt.to/a/4c7W
Public reporting of how physicians and hospitals perform in quality of care measures leads to improved care for patients. A collaborative team of researchers led by Geoffrey C. Lamb, M.D., professor of internal medicine at the Medical College of Wisconsin, published their findings in the March 2013 edition of Health Affairs.
The General Public Support Legal Interventions To Fight Obesity, Noncommunicable Diseases: Survey
http://mnt.to/a/4c7w
The public is very supportive of government action aimed at changing lifestyle choices that can lead to obesity, diabetes, and other noncommunicable diseases - but they're less likely to support such interventions if they're viewed as intrusive or coercive, according to a new Harvard School of Public Health (HSPH) study.
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** EAR, NOSE AND THROAT News **
Newly Identified Biomarkers May Help Predict Progression Of Barrett's Esophagus To Esophageal Adenocarcinoma
http://mnt.to/a/4c86
Expression of most microRNAs was similar between the two conditions. A small number were differentially expressed. These microRNAs could be biomarkers for early diagnosis of progression.A series of microRNA expression signatures that may help to define progression of the precancerous condition Barrett's esophagus into esophageal adenocarcinoma was reported recently in Cancer Prevention Research, a journal of the American Association for Cancer Research.
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** EYE HEALTH / BLINDNESS News **
Study Confirms Rapid Effectiveness Of Temporary, Nonsurgical Alternative To LASIK
http://mnt.to/a/4c8n
A contact lens technique called overnight orthokeratology (OK) brings rapid improvement in vision for nearsighted patients. Now a new study shows that OK treatment works mainly by flattening the front of the cornea, reports a recent study, "Posterior Corneal Shape Changes in Myopic Overnight Orthokeratology", appearing in the March issue of Optometry and Vision Science, official journal of the American Academy of Optometry.
Researchers Identify Seven New Genes Associated With Macular Degeneration
http://mnt.to/a/4c88
Researchers from the University of Miami Miller School of Medicine collaborated with an international team to identify seven new genes associated with agerelated macular degeneration (AMD), the most common form of vision loss in older people.
Many Children With Retinoblastoma May Safely Forego Adjuvant Chemotherapy
http://mnt.to/a/4c7G
New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Breath Test Could Detect And Diagnose Stomach Cancer
http://mnt.to/a/4c8V
A simple test that analyzes the chemical signature of a patient's exhaled breath could help diagnose stomach cancer, according to new research by scientists from Israel and China reported online in the British Journal of Cancer this week.
Colonoscopy May Reduce Advanced Cancer Risk By 70%
http://mnt.to/a/4c8F
Colonoscopy screening reduces the risk of advanced colorectal cancer by about 70% in average-risk adults.The finding came from a new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania and was published in the journal Annals of Internal Medicine.
Visceral Fat Causally Linked To Intestinal Cancer
http://mnt.to/a/4c87
Loss of fat by surgical removal or a calorierestricted diet reduced likelihood of developing intestinal tumors. Differences were found between male and female mice. Study emphasizes the need for strategies to reduce visceral fat.
----------------------------------------------
** GENETICS News **
The Dramatic Differences Among People With Schizophrenia May Be Explained By A Single Gene
http://mnt.to/a/4c8q
Some of the dramatic differences seen among patients with schizophrenia may be explained by a single gene that regulates a group of other schizophrenia risk genes. These findings appear in a new imaging-genetics study from the Centre for Addiction and Mental Health (CAMH).
Revision Of Latest Methodologies For Studying Evolution And Interaction Of Proteins
http://mnt.to/a/4c8p
Spanish National Cancer Research Centre (CNIO) researchers Alfonso Valencia, Director of the Structural Biology and Biocomputing Programme and David de Juan, jointly with Florencio Pazos, from the Spanish National Centre for Biotechnology (CNB-CSIC), publish a review on the latest computational methods that, based on evolutionary principles, are revolutionising the field of analysis and prediction of protein structure, function and protein-protein interactions, as well as the short- and long-term expectations for the field.
New Gene Variant May Explain Psychotic Features In Bipolar Disorder
http://mnt.to/a/4c8g
Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis.
Researchers Identify Seven New Genes Associated With Macular Degeneration
http://mnt.to/a/4c88
Researchers from the University of Miami Miller School of Medicine collaborated with an international team to identify seven new genes associated with agerelated macular degeneration (AMD), the most common form of vision loss in older people.
Advancing Knowledge Of HIV Impact On Hepatitis C Infection And Genes That May Thwart HCV
http://mnt.to/a/4c7V
Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus (HCV), co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.
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** HEALTH INSURANCE / MEDICAL INSURANCE News **
In Late-Stage Diagnosis Of Breast Cancer, Neighborhood Poverty And Health Insurance Are Common
http://mnt.to/a/4c8v
Home may be where the heart is, but where you live could affect your health."Regardless of geographic location, women who live in high poverty areas or are uninsured are at greatest risk of being diagnosed with breast cancer at a later stage," said lead author Kevin Henry, Department of Geography, University of Utah.
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** HEART DISEASE News **
Insomnia Triples Risk of Heart Failure
http://mnt.to/a/4cbg
The risk of developing heart failure tripes for people who suffer from insomnia.The finding came from a new study, the largest yet to examine the association, and was published in the European Heart Journal.
Tackling Obesity May Reverse Heart Disease Damage
http://mnt.to/a/4c7B
Johns Hopkins research on obese mice finds that the impact of dieting and losing weight benefits the heart health of the young, but not the older onesIn a study of the impact of weight loss on reversing heart damage from obesity, Johns Hopkins researchers found that poor heart function in young obese mice can be reversed when the animals lose weight from a low-calorie diet.
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** HIV / AIDS News **
Boehringer Ingelheim Announces Interim Results From A Phase III Trial In HIV Patients Co-Infected With Chronic Hepatitis C
http://mnt.to/a/4cb5
80 percent of patients achieved early treatment success* with faldaprevir^ plus PegIFN/RBV highlighting the potential to reduce treatment duration from 48 to 24 weeks. Interim results indicate potent activity of faldaprevir in HCV/HIV co-infected patientsInterim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).
Advancing Knowledge Of HIV Impact On Hepatitis C Infection And Genes That May Thwart HCV
http://mnt.to/a/4c7V
Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus (HCV), co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.
Findings Of 2 Important Studies Published In AIDS Journal
http://mnt.to/a/4c7P
The results of two important studies have been published in the March issue of AIDS, the official journal of the International AIDS Society. One study notes that screening for HIV should be performed more frequently - up to every three months for the highest-risk patients, while low-risk groups to be tested every three years.
Viral Reservoirs In HIV-Infected Teens Reduced By Early Antiretroviral Treatment
http://mnt.to/a/4c7H
A study led by University of Massachusetts Medical School professor and immunologist Katherine Luzuriaga, MD, and Johns Hopkins Children's Center virologist Deborah Persaud, MD, highlights the long-term benefits of early antiretroviral therapy (ART) initiated in infants.
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** IMMUNE SYSTEM / VACCINES News **
International Study: Excess Dietary Salt May Drive The Development Of Autoimmune Diseases
http://mnt.to/a/4cb7
Increased dietary salt intake can induce a group of aggressive immune cells that are involved in triggering and sustaining autoimmune diseases. This is the result of a study conducted by Dr. Markus Kleinewietfeld, Prof.
Hope For New Therapeutic Approaches To Many Of The World's Debilitating Or Fatal Diseases
http://mnt.to/a/4c7y
Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.This finding, reported in Proceedings of the National Academy of Sciences, could ultimately lead to new therapeutic approaches to many of the world's debilitating or fatal diseases.
Vaccine That May Help Protect Newborn Babies
http://mnt.to/a/4c7v
The underdeveloped immune systems of newborns don't respond to most vaccines, leaving them at high risk for infections like rotavirus, pertussis (whooping cough) and pneumococcus. Researchers at Boston Children's Hospital have identified a potent compound that activates immune responses in newborns' white blood cells substantially better than anything previously tested, and that could potentially make vaccines effective right at birth.
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** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Drug-Resistant Superbug Hits U.S. Hospitals
http://mnt.to/a/4cbf
More evidence has been revealed that untreatable, antibiotic-resistant infections from a rare but life-threatening superbug are on the rise in U.S. hospitals, creating a growing public health concern, officials said Tuesday.
Maternal Diet Important Predictor Of Severity For Infant RSV
http://mnt.to/a/4c7Y
An important predictor of the severity of respiratory syncytial virus (RSV) in infants may be what their mothers ate during pregnancy, according to a Vanderbilt study published in the American Journal of Respiratory and Critical Care Medicine.
Need For Routine Antibiotics In Advanced Brain Procedures Questioned
http://mnt.to/a/4c7N
Patients undergoing cerebral angiography and neurointerventional procedures on the brain are at very low risk of infection - even without preventive antibiotics, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.
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** LIVER DISEASE / HEPATITIS News **
Boehringer Ingelheim Announces Interim Results From A Phase III Trial In HIV Patients Co-Infected With Chronic Hepatitis C
http://mnt.to/a/4cb5
80 percent of patients achieved early treatment success* with faldaprevir^ plus PegIFN/RBV highlighting the potential to reduce treatment duration from 48 to 24 weeks. Interim results indicate potent activity of faldaprevir in HCV/HIV co-infected patientsInterim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).
Advancing Knowledge Of HIV Impact On Hepatitis C Infection And Genes That May Thwart HCV
http://mnt.to/a/4c7V
Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus (HCV), co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.
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** MEDICAL DEVICES / DIAGNOSTICS News **
Eye Movement Analyzer May Diagnose Stroke
http://mnt.to/a/4cbh
A bedside device that expertly analyzes eye movements could one day save lives by helping doctors determine whether stroke is the cause of a patient's disabling, severe, continuous dizziness, or a more benign condition like vertigo.
Breath Test Could Detect And Diagnose Stomach Cancer
http://mnt.to/a/4c8V
A simple test that analyzes the chemical signature of a patient's exhaled breath could help diagnose stomach cancer, according to new research by scientists from Israel and China reported online in the British Journal of Cancer this week.
Detection Of Parkinson's Disease Brain Rhythms May Lead To Better Way To Monitor, Treat Disease
http://mnt.to/a/4c7s
A team of scientists and clinicians at UC San Francisco has discovered how to detect abnormal brain rhythms associated with Parkinson's by implanting electrodes within the brains of people with the disease.
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** MEDICARE / MEDICAID / SCHIP News **
Use Hospice By Medicare Patients Offers Better Care At A Lower Cost To The Government
http://mnt.to/a/4c7z
Medicare patients who enrolled in hospice received better care at a significantly lower cost to the government than those who did not use the Medicare hospice benefit. The data indicate that annual savings to Medicare could amount to $2.
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** MEN'S HEALTH News **
Findings Of 2 Important Studies Published In AIDS Journal
http://mnt.to/a/4c7P
The results of two important studies have been published in the March issue of AIDS, the official journal of the International AIDS Society. One study notes that screening for HIV should be performed more frequently - up to every three months for the highest-risk patients, while low-risk groups to be tested every three years.
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** MENTAL HEALTH News **
People With Mental Illness At Highly Increased Risk Of Being Murder Victims
http://mnt.to/a/4c8d
Risk highest among those with substance use disordersPeople with mental disorders have a highly increased risk of being victims of homicide, a large study published today on bmj.com suggests.
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** MRI / PET / ULTRASOUND News **
Eye Movement Analyzer May Diagnose Stroke
http://mnt.to/a/4cbh
A bedside device that expertly analyzes eye movements could one day save lives by helping doctors determine whether stroke is the cause of a patient's disabling, severe, continuous dizziness, or a more benign condition like vertigo.
----------------------------------------------
** MULTIPLE SCLEROSIS News **
International Study: Excess Dietary Salt May Drive The Development Of Autoimmune Diseases
http://mnt.to/a/4cb7
Increased dietary salt intake can induce a group of aggressive immune cells that are involved in triggering and sustaining autoimmune diseases. This is the result of a study conducted by Dr. Markus Kleinewietfeld, Prof.
----------------------------------------------
** MUSCULAR DYSTROPHY / ALS News **
New Options For Stroke ALS, Spinal Cord Injury Likely Following Discovery Of 'Executioner' Protein
http://mnt.to/a/4c8w
Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released in the Proceedings of the National Academy of Sciences journal.Alvaro Estevez, an associate professor at the University of Central Florida's College of Medicine, led the multi-university team that made the discovery, which could eventually help scientists develop new therapies to combat a host of conditions from stroke to Lou Gehrig's diseaseResearchers have long known that oxidative stress damages cells and results in neurodegeneration, inflammation and aging.
Hope For New Therapeutic Approaches To Many Of The World's Debilitating Or Fatal Diseases
http://mnt.to/a/4c7y
Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.This finding, reported in Proceedings of the National Academy of Sciences, could ultimately lead to new therapeutic approaches to many of the world's debilitating or fatal diseases.
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** NEUROLOGY / NEUROSCIENCE News **
New Options For Stroke ALS, Spinal Cord Injury Likely Following Discovery Of 'Executioner' Protein
http://mnt.to/a/4c8w
Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released in the Proceedings of the National Academy of Sciences journal.Alvaro Estevez, an associate professor at the University of Central Florida's College of Medicine, led the multi-university team that made the discovery, which could eventually help scientists develop new therapies to combat a host of conditions from stroke to Lou Gehrig's diseaseResearchers have long known that oxidative stress damages cells and results in neurodegeneration, inflammation and aging.
Revision Of Latest Methodologies For Studying Evolution And Interaction Of Proteins
http://mnt.to/a/4c8p
Spanish National Cancer Research Centre (CNIO) researchers Alfonso Valencia, Director of the Structural Biology and Biocomputing Programme and David de Juan, jointly with Florencio Pazos, from the Spanish National Centre for Biotechnology (CNB-CSIC), publish a review on the latest computational methods that, based on evolutionary principles, are revolutionising the field of analysis and prediction of protein structure, function and protein-protein interactions, as well as the short- and long-term expectations for the field.
Activity-Based Restorative Therapy Programs May Provide Substantial Benefits For Persons With Chronic Spinal Cord Injury
http://mnt.to/a/4c8m
A new study by Kennedy Krieger Institute's International Center for Spinal Cord Injury (Epub ahead of print) finds that long-term lower extremity functional electrical stimulation (FES) cycling, as part of a rehabilitation regimen, is associated with substantial improvements in individuals with chronic spinal cord injury (SCI).
Tracking Human Brain Activity Shows How The Brain Loses And Regains Consciousness
http://mnt.to/a/4c83
Since the mid-1800s, doctors have used drugs to induce general anesthesia in patients undergoing surgery. Despite their widespread use, little is known about how these drugs create such a profound loss of consciousness.
Need For Routine Antibiotics In Advanced Brain Procedures Questioned
http://mnt.to/a/4c7N
Patients undergoing cerebral angiography and neurointerventional procedures on the brain are at very low risk of infection - even without preventive antibiotics, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.
The Brain Adds New Cells During Puberty To Help Navigate The Complex Social World Of Adulthood
http://mnt.to/a/4c7M
Two Michigan State University neuroscientists report in the current issue of the Proceedings of the National Academy of Sciences.Scientists used to think the brain cells you're born with are all you get.
Hope For New Therapeutic Approaches To Many Of The World's Debilitating Or Fatal Diseases
http://mnt.to/a/4c7y
Researchers have discovered how oxidative stress can turn to the dark side a cellular protein that's usually benign, and make it become a powerful, unwanted accomplice in neuronal death.This finding, reported in Proceedings of the National Academy of Sciences, could ultimately lead to new therapeutic approaches to many of the world's debilitating or fatal diseases.
How The Brain Tires When Exercising Has Implications For Doping In Sport, Motor Contol, Depression
http://mnt.to/a/4c7x
A marathon runner approaches the finishing line, but suddenly the sweaty athlete collapses to the ground. Everyone probably assumes that this is because he has expended all energy in his muscles.
Detection Of Parkinson's Disease Brain Rhythms May Lead To Better Way To Monitor, Treat Disease
http://mnt.to/a/4c7s
A team of scientists and clinicians at UC San Francisco has discovered how to detect abnormal brain rhythms associated with Parkinson's by implanting electrodes within the brains of people with the disease.
Woman's Exposure To Stress During Pregnancy Impacts Fetal Brain Via The Placenta
http://mnt.to/a/4c7r
The mammalian placenta is more than just a filter through which nutrition and oxygen are passed from a mother to her unborn child. According to a new study by a research group from the University of Pennsylvania School of Veterinary Medicine, if a mother is exposed to stress during pregnancy, her placenta translates that experience to her fetus by altering levels of a protein that affects the developing brains of male and female offspring differently.
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** NUTRITION / DIET News **
International Study: Excess Dietary Salt May Drive The Development Of Autoimmune Diseases
http://mnt.to/a/4cb7
Increased dietary salt intake can induce a group of aggressive immune cells that are involved in triggering and sustaining autoimmune diseases. This is the result of a study conducted by Dr. Markus Kleinewietfeld, Prof.
Vitamin B12 Deficiency Prevalent Among Refugees
http://mnt.to/a/4c85
New research from the University of Adelaide has discovered a high prevalence of vitamin B12 deficiency among refugees, prompting calls for refugees to be routinely screened for the problem soon after they arrive.
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** OBESITY / WEIGHT LOSS / FITNESS News **
Tackling Obesity May Reverse Heart Disease Damage
http://mnt.to/a/4c7B
Johns Hopkins research on obese mice finds that the impact of dieting and losing weight benefits the heart health of the young, but not the older onesIn a study of the impact of weight loss on reversing heart damage from obesity, Johns Hopkins researchers found that poor heart function in young obese mice can be reversed when the animals lose weight from a low-calorie diet.
The General Public Support Legal Interventions To Fight Obesity, Noncommunicable Diseases: Survey
http://mnt.to/a/4c7w
The public is very supportive of government action aimed at changing lifestyle choices that can lead to obesity, diabetes, and other noncommunicable diseases - but they're less likely to support such interventions if they're viewed as intrusive or coercive, according to a new Harvard School of Public Health (HSPH) study.
----------------------------------------------
** PAIN / ANESTHETICS News **
Cognitive Behavioral Therapy Helps To Treat Diabetic Neuropathies
http://mnt.to/a/4c84
Researchers at Boston University School of Medicine (BUSM) and VA Boston Healthcare System (VA BHS) have found that cognitive behavioral therapy (CBT) can help relieve pain for people with painful diabetic neuropathies.
Tracking Human Brain Activity Shows How The Brain Loses And Regains Consciousness
http://mnt.to/a/4c83
Since the mid-1800s, doctors have used drugs to induce general anesthesia in patients undergoing surgery. Despite their widespread use, little is known about how these drugs create such a profound loss of consciousness.
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** PALLIATIVE CARE / HOSPICE CARE News **
Use Hospice By Medicare Patients Offers Better Care At A Lower Cost To The Government
http://mnt.to/a/4c7z
Medicare patients who enrolled in hospice received better care at a significantly lower cost to the government than those who did not use the Medicare hospice benefit. The data indicate that annual savings to Medicare could amount to $2.
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** PARKINSON'S DISEASE News **
Detection Of Parkinson's Disease Brain Rhythms May Lead To Better Way To Monitor, Treat Disease
http://mnt.to/a/4c7s
A team of scientists and clinicians at UC San Francisco has discovered how to detect abnormal brain rhythms associated with Parkinson's by implanting electrodes within the brains of people with the disease.
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** PEDIATRICS / CHILDREN'S HEALTH News **
Maternal Diet Important Predictor Of Severity For Infant RSV
http://mnt.to/a/4c7Y
An important predictor of the severity of respiratory syncytial virus (RSV) in infants may be what their mothers ate during pregnancy, according to a Vanderbilt study published in the American Journal of Respiratory and Critical Care Medicine.
The Brain Adds New Cells During Puberty To Help Navigate The Complex Social World Of Adulthood
http://mnt.to/a/4c7M
Two Michigan State University neuroscientists report in the current issue of the Proceedings of the National Academy of Sciences.Scientists used to think the brain cells you're born with are all you get.
Better Tools Required To Evaluate Newborn Intensive Care Units And Improve Care For Vulnerable Infants
http://mnt.to/a/4c7J
Scoring methods commonly used to evaluate Newborn Intensive Care Units (NICU) are inconsistent, according to new research from the University of Michigan.The research published last week in the journal Pediatrics compared 10 well-known scores that have been developed to evaluate NICUs.
Viral Reservoirs In HIV-Infected Teens Reduced By Early Antiretroviral Treatment
http://mnt.to/a/4c7H
A study led by University of Massachusetts Medical School professor and immunologist Katherine Luzuriaga, MD, and Johns Hopkins Children's Center virologist Deborah Persaud, MD, highlights the long-term benefits of early antiretroviral therapy (ART) initiated in infants.
Many Children With Retinoblastoma May Safely Forego Adjuvant Chemotherapy
http://mnt.to/a/4c7G
New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether.
Vaccine That May Help Protect Newborn Babies
http://mnt.to/a/4c7v
The underdeveloped immune systems of newborns don't respond to most vaccines, leaving them at high risk for infections like rotavirus, pertussis (whooping cough) and pneumococcus. Researchers at Boston Children's Hospital have identified a potent compound that activates immune responses in newborns' white blood cells substantially better than anything previously tested, and that could potentially make vaccines effective right at birth.
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** PHARMA INDUSTRY / BIOTECH INDUSTRY News **
Despite Improvement, Distribution Of Free Samples To Patients And Office Calls To Physicians Still Major Part Of Pharmaceutical Advertising
http://mnt.to/a/4c7X
The pharmaceutical industry has pulled back on marketing to physicians and consumers, yet some enduring patterns persist. According to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health, advertising peaked in 2004, with industry promotion to physicians declining nearly 25 percent by 2010, to $27.
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** PREGNANCY / OBSTETRICS News **
Hospital C-Section Rates Vary Widely
http://mnt.to/a/4c8D
The most common surgery in the United States is cesarean delivery (c-section), and it is performed on 1.67 million women every year. Surprisingly, hospital cesarean rates now vary widely across the U.
Support Interventions May Decrease Stress Hormone Which Foreshadows Postpartum Depression In New Mothers
http://mnt.to/a/4c8h
Women who receive strong social support from their families during pregnancy appear to be protected from sharp increases in a particular stress hormone, making them less likely to develop postpartum depression, according to a new study published in Clinical Psychological Science, a journal of the Association for Psychological Science.
Vitamin B12 Deficiency Prevalent Among Refugees
http://mnt.to/a/4c85
New research from the University of Adelaide has discovered a high prevalence of vitamin B12 deficiency among refugees, prompting calls for refugees to be routinely screened for the problem soon after they arrive.
Woman's Exposure To Stress During Pregnancy Impacts Fetal Brain Via The Placenta
http://mnt.to/a/4c7r
The mammalian placenta is more than just a filter through which nutrition and oxygen are passed from a mother to her unborn child. According to a new study by a research group from the University of Pennsylvania School of Veterinary Medicine, if a mother is exposed to stress during pregnancy, her placenta translates that experience to her fetus by altering levels of a protein that affects the developing brains of male and female offspring differently.
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** PREVENTIVE MEDICINE News **
Colonoscopy May Reduce Advanced Cancer Risk By 70%
http://mnt.to/a/4c8F
Colonoscopy screening reduces the risk of advanced colorectal cancer by about 70% in average-risk adults.The finding came from a new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania and was published in the journal Annals of Internal Medicine.
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** PRIMARY CARE / GENERAL PRACTICE News **
Despite Improvement, Distribution Of Free Samples To Patients And Office Calls To Physicians Still Major Part Of Pharmaceutical Advertising
http://mnt.to/a/4c7X
The pharmaceutical industry has pulled back on marketing to physicians and consumers, yet some enduring patterns persist. According to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health, advertising peaked in 2004, with industry promotion to physicians declining nearly 25 percent by 2010, to $27.
Patients Benefit From Quality Of Care Measures
http://mnt.to/a/4c7W
Public reporting of how physicians and hospitals perform in quality of care measures leads to improved care for patients. A collaborative team of researchers led by Geoffrey C. Lamb, M.D., professor of internal medicine at the Medical College of Wisconsin, published their findings in the March 2013 edition of Health Affairs.
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** PSYCHOLOGY / PSYCHIATRY News **
Anger Due To Delusions Associated With Violence, Psychosis
http://mnt.to/a/4cb4
JAMA Psychiatry Study HighlightsJeremy W. Coid, M.D., and colleagues from Queen Mary University of London, Forensic Psychiatry Research Unit, Barts, and the London School of Medicine and Dentistry, Wolfson Institute of Preventive Medicine, England, investigated which delusional beliefs and characteristics are associated with violent behavior during a first episode of psychosis.
Ostracism Is A Double-Edged Sword
http://mnt.to/a/4c8t
If you think giving someone the cold shoulder inflicts pain only on them, beware. A new study shows that individuals who deliberately shun another person are equally distressed by the experience.
Reducing Effects Of Traumatic Events At The Molecular Level
http://mnt.to/a/4c8j
Reducing fear and stress following a traumatic event could be as simple as providing a protein synthesis blocker to the brain, report a team of researchers from McLean Hospital, Harvard Medical School, McGill University, and Massachusetts General Hospital in a paper published in the Proceedings of the National Academy of Sciences.
Cognitive Behavioral Therapy Helps To Treat Diabetic Neuropathies
http://mnt.to/a/4c84
Researchers at Boston University School of Medicine (BUSM) and VA Boston Healthcare System (VA BHS) have found that cognitive behavioral therapy (CBT) can help relieve pain for people with painful diabetic neuropathies.
Distress After Episodes Of Sleep Paralysis
http://mnt.to/a/4c7L
Ever find yourself briefly paralyzed as you're falling asleep or just waking up? It's a phenomenon is called sleep paralysis, and it's often accompanied by vivid sensory or perceptual experiences, which can include complex and disturbing hallucinations and intense fear.
New Moms Suffer More Obsessive-Compulsive Symptoms Than General Population
http://mnt.to/a/4c7t
A new mother may constantly worry and check to see if her baby is still breathing. Or she may fret about germs, obsessing whether she's properly sterilized the bottles, then wash and rewash them.
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** PUBLIC HEALTH News **
Drug-Resistant Superbug Hits U.S. Hospitals
http://mnt.to/a/4cbf
More evidence has been revealed that untreatable, antibiotic-resistant infections from a rare but life-threatening superbug are on the rise in U.S. hospitals, creating a growing public health concern, officials said Tuesday.
UK Among Unhealthiest Countries in Europe, Despite Free Medical Care
http://mnt.to/a/4c8G
The United Kingdom has fared badly in health when compared to its Western European neighbors and Australia, in spite of sixty years of free universal health care, considerable increases in health care spending, and the introduction of several nationwide health initiatives, researchers reported in The Lancet.
Health Secretary Plans To Tackle UK's High Cardiovascular Disease Death Rate
http://mnt.to/a/4c8C
Health Secretary Jeremy Hunt has just announced that the UK is developing a new plan to tackle cardiovascular disease (CVD) which could save up to 30,000 lives over the next several years. The UK is behind a lot of other Western countries in managing cardiovascular diseases.
In Late-Stage Diagnosis Of Breast Cancer, Neighborhood Poverty And Health Insurance Are Common
http://mnt.to/a/4c8v
Home may be where the heart is, but where you live could affect your health."Regardless of geographic location, women who live in high poverty areas or are uninsured are at greatest risk of being diagnosed with breast cancer at a later stage," said lead author Kevin Henry, Department of Geography, University of Utah.
Vitamin B12 Deficiency Prevalent Among Refugees
http://mnt.to/a/4c85
New research from the University of Adelaide has discovered a high prevalence of vitamin B12 deficiency among refugees, prompting calls for refugees to be routinely screened for the problem soon after they arrive.
Patients Benefit From Quality Of Care Measures
http://mnt.to/a/4c7W
Public reporting of how physicians and hospitals perform in quality of care measures leads to improved care for patients. A collaborative team of researchers led by Geoffrey C. Lamb, M.D., professor of internal medicine at the Medical College of Wisconsin, published their findings in the March 2013 edition of Health Affairs.
Global Burden Of Disease And Injury Attributable To Alcohol Is Large And Growing
http://mnt.to/a/4c7R
A new study by the Centre for Addiction and Mental Health (CAMH) shows that alcohol is now the third leading cause of the global burden of disease and injury, despite the fact most adults worldwide abstain from drinking.
Better Tools Required To Evaluate Newborn Intensive Care Units And Improve Care For Vulnerable Infants
http://mnt.to/a/4c7J
Scoring methods commonly used to evaluate Newborn Intensive Care Units (NICU) are inconsistent, according to new research from the University of Michigan.The research published last week in the journal Pediatrics compared 10 well-known scores that have been developed to evaluate NICUs.
Measures Need To Be Taken To Prevent A Billion Deaths From Tobacco By End Of Century
http://mnt.to/a/4c7F
If the world's nations are going to prevent tobacco smoking from causing one projected billion deaths by the end of this century, they must: Make tobacco control part of the agendas of United Nation's and other development agencies worldwide; Assure every sector of a nation including health, trade and finance officials work collectively to protect not only health but the harm tobacco places on their economy by passing laws to reduce use; Place health as the centerpiece of any decision on a trade treaty that includes tobacco; Diligently work toward a goal of reducing the prevalence rate of smoking to less than five percent world-wide by 2048, basically ending its use.
Call For Prison Health Care Reform In Canada
http://mnt.to/a/4c7C
Canada needs to reform its patchwork system of prison health care that does not adequately care for prisoners' complex health care needs, argues an editorial in CMAJ (Canadian Medical Association Journal).
The General Public Support Legal Interventions To Fight Obesity, Noncommunicable Diseases: Survey
http://mnt.to/a/4c7w
The public is very supportive of government action aimed at changing lifestyle choices that can lead to obesity, diabetes, and other noncommunicable diseases - but they're less likely to support such interventions if they're viewed as intrusive or coercive, according to a new Harvard School of Public Health (HSPH) study.
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** REHABILITATION / PHYSICAL THERAPY News **
Activity-Based Restorative Therapy Programs May Provide Substantial Benefits For Persons With Chronic Spinal Cord Injury
http://mnt.to/a/4c8m
A new study by Kennedy Krieger Institute's International Center for Spinal Cord Injury (Epub ahead of print) finds that long-term lower extremity functional electrical stimulation (FES) cycling, as part of a rehabilitation regimen, is associated with substantial improvements in individuals with chronic spinal cord injury (SCI).
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** RESPIRATORY / ASTHMA News **
Maternal Diet Important Predictor Of Severity For Infant RSV
http://mnt.to/a/4c7Y
An important predictor of the severity of respiratory syncytial virus (RSV) in infants may be what their mothers ate during pregnancy, according to a Vanderbilt study published in the American Journal of Respiratory and Critical Care Medicine.
----------------------------------------------
** SCHIZOPHRENIA News **
The Dramatic Differences Among People With Schizophrenia May Be Explained By A Single Gene
http://mnt.to/a/4c8q
Some of the dramatic differences seen among patients with schizophrenia may be explained by a single gene that regulates a group of other schizophrenia risk genes. These findings appear in a new imaging-genetics study from the Centre for Addiction and Mental Health (CAMH).
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** SEXUAL HEALTH / STDS News **
Review Of Contraceptive Options For Women Over 40
http://mnt.to/a/4c7D
Despite declining fertility, women over age 40 still require effective contraception if they wish to avoid pregnancy. A review article outlines the risks and benefits of various contraceptive options for these women.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Insomnia Triples Risk of Heart Failure
http://mnt.to/a/4cbg
The risk of developing heart failure tripes for people who suffer from insomnia.The finding came from a new study, the largest yet to examine the association, and was published in the European Heart Journal.
Regular Exercise May Be Key To Good Sleep
http://mnt.to/a/4c7Q
Exercise can affect your sleep. The results of the National Sleep Foundation's 2013 Sleep in America® poll show a compelling association between exercise and better sleep. "Exercise is great for sleep.
Distress After Episodes Of Sleep Paralysis
http://mnt.to/a/4c7L
Ever find yourself briefly paralyzed as you're falling asleep or just waking up? It's a phenomenon is called sleep paralysis, and it's often accompanied by vivid sensory or perceptual experiences, which can include complex and disturbing hallucinations and intense fear.
----------------------------------------------
** SMOKING / QUIT SMOKING News **
Measures Need To Be Taken To Prevent A Billion Deaths From Tobacco By End Of Century
http://mnt.to/a/4c7F
If the world's nations are going to prevent tobacco smoking from causing one projected billion deaths by the end of this century, they must: Make tobacco control part of the agendas of United Nation's and other development agencies worldwide; Assure every sector of a nation including health, trade and finance officials work collectively to protect not only health but the harm tobacco places on their economy by passing laws to reduce use; Place health as the centerpiece of any decision on a trade treaty that includes tobacco; Diligently work toward a goal of reducing the prevalence rate of smoking to less than five percent world-wide by 2048, basically ending its use.
----------------------------------------------
** SPORTS MEDICINE / FITNESS News **
Regular Exercise May Be Key To Good Sleep
http://mnt.to/a/4c7Q
Exercise can affect your sleep. The results of the National Sleep Foundation's 2013 Sleep in America® poll show a compelling association between exercise and better sleep. "Exercise is great for sleep.
How The Brain Tires When Exercising Has Implications For Doping In Sport, Motor Contol, Depression
http://mnt.to/a/4c7x
A marathon runner approaches the finishing line, but suddenly the sweaty athlete collapses to the ground. Everyone probably assumes that this is because he has expended all energy in his muscles.
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** STROKE News **
Eye Movement Analyzer May Diagnose Stroke
http://mnt.to/a/4cbh
A bedside device that expertly analyzes eye movements could one day save lives by helping doctors determine whether stroke is the cause of a patient's disabling, severe, continuous dizziness, or a more benign condition like vertigo.
New Options For Stroke ALS, Spinal Cord Injury Likely Following Discovery Of 'Executioner' Protein
http://mnt.to/a/4c8w
Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released in the Proceedings of the National Academy of Sciences journal.Alvaro Estevez, an associate professor at the University of Central Florida's College of Medicine, led the multi-university team that made the discovery, which could eventually help scientists develop new therapies to combat a host of conditions from stroke to Lou Gehrig's diseaseResearchers have long known that oxidative stress damages cells and results in neurodegeneration, inflammation and aging.
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** TRANSPLANTS / ORGAN DONATIONS News **
Children's Hospital Of Pittsburgh Of UPMC Study Shows Increase In Liver Transplantation For Hepatoblastoma
http://mnt.to/a/4c8f
Liver transplantation for hepatoblastoma, the most common liver malignancy in children, is on the rise because more tumors are being detected earlier, improving outcomes for these sick patients, according to a Children's Hospital of Pittsburgh of UPMC study.
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** TROPICAL DISEASES News **
Researchers Observed How West Nile Virus Is Transmitted Between Generations
http://mnt.to/a/4c8r
In California Culex mosquitoes are considered to be the principle vectors of West Nile virus (WNV), which infects birds, humans, and other mammals during the summer. In addition, these mosquitoes may also serve as overwintering reservoir hosts as the virus is passed "vertically" from female mosquito to egg, then larva, and then adult.
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** UROLOGY / NEPHROLOGY News **
Mirabegron Found To Be Effective And Well Tolerated In Patients With Overactive Bladder
http://mnt.to/a/4c8k
In a new phase III trial mirabegron, a β3-adrenoceptor agonist, given once daily for 12 weeks, reduced the frequency of incontinence episodes and number of daily urinations, and improved urgency and nocturia in adults with overactive bladder (OAB) compared to those in a placebo group.
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** VETERINARY News **
Why Cats Lack A Sweet Tooth: New American Chemical Society Video
http://mnt.to/a/4c7Z
Do cats purrr-ferrr sardines or sweets? The American Chemical Society (ACS), the world's largest scientific society, has released a new Bytesize Science video that explains why cats, unlike humans and other mammals, are indifferent to sweet flavors.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Review Of Contraceptive Options For Women Over 40
http://mnt.to/a/4c7D
Despite declining fertility, women over age 40 still require effective contraception if they wish to avoid pregnancy. A review article outlines the risks and benefits of various contraceptive options for these women.
New Moms Suffer More Obsessive-Compulsive Symptoms Than General Population
http://mnt.to/a/4c7t
A new mother may constantly worry and check to see if her baby is still breathing. Or she may fret about germs, obsessing whether she's properly sterilized the bottles, then wash and rewash them.
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