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** ALZHEIMER'S / DEMENTIA News **
ALS/FTD Neurodegeneration May Be Caused By 'RNA Sponge' Mechanism
http://mnt.to/a/4cGs
The most common genetic cause of both ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) was recently identified as an alteration in the gene C9orf72. But how the mutation causes neurodegenerative disease appeared mysterious.
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** ANXIETY / STRESS News **
Should Suicidal Patients At Emergency Departments Be Asked About Gun Access?
http://mnt.to/a/4cFF
Although guns are used in over half of all American suicides, a new study shows that many emergency room doctors and nurses do not routinely ask suicidal patients about their access to firearms.
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** BIOLOGY / BIOCHEMISTRY News **
Biomechanical Origins Of Common Eye Diseases Easier To Study With New "Stretched Tissue" Approach
http://mnt.to/a/4cJz
Until now, researchers looking for the origins of eye diseases like detached retina and glaucoma have focused on biochemical processes. Now using approaches based on new technology that grows retinal tissue under tension similar to how it grows in nature, researchers in Sweden suggest biomechanical processes may also play an important part and help explain why people suffer vision loss in these eye diseases.
Target Meeting's 2nd World Virology & Microbiology Online Conference Held On April 16-18, 2013: Join For Free
http://mnt.to/a/4cHQ
A Free Virtual Virology & Microbiology Conference at Targetmeeting.com featuring 60 live presentations (12 sessions) from academic and industry experts around the world. Computer and internet connection are required.
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** BLOOD / HEMATOLOGY News **
Susceptibility To Some Viral Infections May Be Increased By Newly Approved Blood Thinner
http://mnt.to/a/4cGy
A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.
Link Discovered Between Blood Clotting And Immune Response
http://mnt.to/a/4cGq
Rice University researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body's immune system. The find could lead to new treatments for thousands of patients who suffer from inflammatory diseases and disorders that cause abnormal blood clotting.
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** BREAST CANCER News **
Surgical Removal Of Lung Metastases In Breast Cancer Patients May Improve Overall Survival
http://mnt.to/a/4cGX
Results Differ from Previous Research Showing Surgery Was Not a Viable OptionPatients with primary breast cancer that has spread to the lungs may live longer if the lung metastases are surgically removed, according to a study published in the April 2013 issue of The Annals of Thoracic Surgery.
Studying The Epigenetics Of Hormone Therapy Resistance Leads To New Drug Target
http://mnt.to/a/4cG5
A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.
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** CANCER / ONCOLOGY News **
AMD Blindness May Be Avoidable With Anti-Cholesterol Drugs
http://mnt.to/a/4cHk
New research that links the causes of age-related macular degeneration (AMD) with clogged arteries suggests anti-cholesterol drugs may halt the eye disease, the leading cause of blindess among older people in the US.
Bowel Cancer Rates Increase In The UK
http://mnt.to/a/4cHf
Over the last three and a half decades, the rate of bowel cancer among British men has increased by 30 percent while there's only been a 6 percent increase in women, according to Cancer Research UK.
Cymbalta Reduces Chemotherapy Induced Neuropathy
http://mnt.to/a/4cHd
Duloxetine, an antidepressant, was shown to reduce painful peripheral neuropathy caused by neurotoxic chemotherapy in a study published in JAMA. Researchers from the University of Michigan School of Nursing added that duloxetine benefited the majority of patients in their study.
Arrival Of Next-Generation Proton Therapy Tool Increases Precision, Expands Types Of Tumors That Can Be Treated At Illinois Center
http://mnt.to/a/4cH3
Pencil beam scanning boosts accuracy, further minimizes radiation delivered to healthy tissueOne of the most precise tools in the fight against cancer is now available to patients in the Midwest.
Single Fathers Due To Cancer: Unique Group Offers Support
http://mnt.to/a/4cGr
Men who have dependent children and whose spouses or partners died from cancer are an overlooked population. These fathers face unique challenges not addressed by traditional grief support groups that often attract an older, female population.
Researchers Warn Against A Potential Backfiring Of Certain Cancer Therapies In Development
http://mnt.to/a/4cG7
Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from the National Cancer Institute in Bethesda, USA, and Didier Picard, from the University of Geneva (UNIGE), Switzerland, this outlook is now being called into question.
Novel Brain Cancer Treatment Uses Genetic Material From Bone Marrow Cells
http://mnt.to/a/4cFK
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of tumor.
Cisplatin-Resistant Cancer Cells Sensitive To Experimental Anticancer Drugs Called PARP Inhibitors
http://mnt.to/a/4cCX
Cisplatin-resistant non-small cell lung cancer cells expressed high levels of hyperactivated PARP1. Cells succumbed to PARP inhibitors in vitro. PARP inhibitor slowed cisplatin-resistant tumor growth in mice.
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** CARDIOVASCULAR / CARDIOLOGY News **
AMD Blindness May Be Avoidable With Anti-Cholesterol Drugs
http://mnt.to/a/4cHk
New research that links the causes of age-related macular degeneration (AMD) with clogged arteries suggests anti-cholesterol drugs may halt the eye disease, the leading cause of blindess among older people in the US.
Imaging Technology Could Lower Coronary Disease Mortality Rate
http://mnt.to/a/4cH4
Patients undergoing angioplasty or other heart-related medical procedures could benefit from a new technology being developed with funding from the National Science Foundation (NSF).Optical imaging technology from Wasatch Photonics Inc.
CABG Surgery Generally Not Associated With Long-Term Cognitive Dysfunction
http://mnt.to/a/4cGW
Nearly All Patients Recover Full Cognitive Function within 8 Weeks Post-SurgeryThe cognitive dysfunction observed in patients who undergo coronary artery bypass grafting (CABG) surgery usually disappears within 8 weeks following surgery, according to a study published in the April 2013 issue of The Annals of Thoracic Surgery.
Clinical Practice Guidelines Address Aortic Valve And Ascending Aorta Procedures
http://mnt.to/a/4cGV
The Society of Thoracic Surgeons (STS) has released a set of clinical practice guidelines to address major advances in the evaluation and management of patients with aortic valve disease. An executive summary of the clinical practice guidelines on aortic valve and ascending aorta procedures appears in the April issue of The Annals of Thoracic Surgery.
Body Mass Index (BMI) And Coronary Heart Disease
http://mnt.to/a/4cGT
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older.
Susceptibility To Some Viral Infections May Be Increased By Newly Approved Blood Thinner
http://mnt.to/a/4cGy
A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.
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** COMPLIANCE News **
Study Examines The Role Adverse Reactions Play In Statin Discontinuation
http://mnt.to/a/4cGb
Despite their well-documented benefits, statins, drugs used to lower cholesterol, are commonly discontinued in routine care. Statin discontinuation has been linked to increased risk for cardiovascular events and death in patients with coronary artery disease; nevertheless, the reasons for discontinuation are only starting to be explored.
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** CONFERENCES News **
Generics And Patent Strategies Update, Central London
http://mnt.to/a/4cHT
SMi Group have announced that there are now just 6 weeks left until they open their doors to the 16th annual conference on Generics and Patent Strategies to be held in to be held in central London on 13th-14th May 2013.
Polytherics And Viventia Sponsor ADC Summit, London 2013
http://mnt.to/a/4cHS
SMi Group are proud to announce that Polytherics, a UK Biotech company and Viventia, a Canadian biopharmaceutical company, will be sponsoring this years 2nd annual ADC Summit taking place on 20 - 21 May, London.
SMi Group Announce Vitalograph And Aerocrine As Sponsors Of Asthma & COPD
http://mnt.to/a/4cHR
SMi Group is pleased to announce Vitalograph and Aerocrine as sponsors of the 9th instalment in the Asthma series, taking place on 15th and 16th April, London."2013 is an exciting year for Vitalograph as we celebrate our 50th anniversary.
Target Meeting's 2nd World Virology & Microbiology Online Conference Held On April 16-18, 2013: Join For Free
http://mnt.to/a/4cHQ
A Free Virtual Virology & Microbiology Conference at Targetmeeting.com featuring 60 live presentations (12 sessions) from academic and industry experts around the world. Computer and internet connection are required.
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** COPD News **
SMi Group Announce Vitalograph And Aerocrine As Sponsors Of Asthma & COPD
http://mnt.to/a/4cHR
SMi Group is pleased to announce Vitalograph and Aerocrine as sponsors of the 9th instalment in the Asthma series, taking place on 15th and 16th April, London."2013 is an exciting year for Vitalograph as we celebrate our 50th anniversary.
Nuclear Medicine Enables Earlier COPD Diagnosis
http://mnt.to/a/4cGp
In vivo ventilation/perfusion (V/Q) imaging can detect early changes to the lung caused by cigarette smoke exposure and provides a noninvasive method for studying lung dysfunction in preclinical models, according to research published in the April issue of The Journal of Nuclear Medicine.
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** DEPRESSION News **
Men More Depressed Than Women If Childless
http://mnt.to/a/4cH9
Men are just as likely as women to want kids, and they feel more depressed, isolated, angry and sad than women if they are childless, according to a new study.The research was presented at the British Sociological Association yearly conference in London on April 3rd.
Adults With Diabetes And Limited Health Literacy Less Likely To Adhere To Prescribed Antidepressants
http://mnt.to/a/4cGP
Adult patients with diabetes who don't understand basic health information are significantly less likely to take newly prescribed antidepressant medication, according to a new Kaiser Permanente study in the Journal of General Internal Medicine.
Should Suicidal Patients At Emergency Departments Be Asked About Gun Access?
http://mnt.to/a/4cFF
Although guns are used in over half of all American suicides, a new study shows that many emergency room doctors and nurses do not routinely ask suicidal patients about their access to firearms.
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** DIABETES News **
Direct Association Between Type 2 Diabetes And Obesity Found
http://mnt.to/a/4cHb
Obesity has been historically known as a risk factor for type 2 diabetes, and now a key mechanism has been found in the immune system that plays a part in the development of obesity-linked type 2 diabetes.
Adults With Diabetes And Limited Health Literacy Less Likely To Adhere To Prescribed Antidepressants
http://mnt.to/a/4cGP
Adult patients with diabetes who don't understand basic health information are significantly less likely to take newly prescribed antidepressant medication, according to a new Kaiser Permanente study in the Journal of General Internal Medicine.
Supplementation Of Alternative Fuels Could Protect The Brain During Hypoglycemia
http://mnt.to/a/4cGg
Tight control of blood glucose levels is critical to mitigating the long-term complications of diabetes; however, the intensive insulin therapy required for this control is frequently accompanied by recurrent episodes of low blood sugar (hypoglycemia).
Visiting Your Doctor Following ER Care For Chest Pain Reduces Risk Of Heart Attack, Death
http://mnt.to/a/4cGc
Seeing a doctor within a month of an emergency room visit for chest pain significantly reduced the risk of heart attack or death among high risk patients, according to research published the American Heart Association journal Circulation.
Disrupting Our Internal Clocks May Lead To A Complete Absence Of 24-Hour Bodily Rhythms And An Immediate Gain In Body Weight
http://mnt.to/a/4cFH
If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. That's because new research published in The FASEB Journal used mice to show that proper sleep patterns are critical for healthy metabolic function, and even mild impairment in our circadian rhythms can lead to serious health consequences, including diabetes and obesity.
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** EAR, NOSE AND THROAT News **
Tonsillectomy Helps Adults Too
http://mnt.to/a/4cHc
Adults who undergo a tonsillectomy have fewer symptoms of pharyngitis, visit their doctors with throat problems less often, and miss work less, researchers from the University of Oulu and Oulu University Hospital, both in Finland, reported in CMAJ (Canadian Medical Association Journal).
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** ERECTILE DYSFUNCTION / PREMATURE EJACULATION News **
Sildenafil Helps Turn 'Bad' White Adipose Tissue Into 'Good And Healthy' Brown Adipose Tissue
http://mnt.to/a/4cFJ
Although sildenafil is best known for promoting erections, it may also serve as a weight loss aid by coaxing our bodies to store more healthy "brown fat" relative to unhealthy "white fat" than it would otherwise do on its own.
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** EYE HEALTH / BLINDNESS News **
Biomechanical Origins Of Common Eye Diseases Easier To Study With New "Stretched Tissue" Approach
http://mnt.to/a/4cJz
Until now, researchers looking for the origins of eye diseases like detached retina and glaucoma have focused on biochemical processes. Now using approaches based on new technology that grows retinal tissue under tension similar to how it grows in nature, researchers in Sweden suggest biomechanical processes may also play an important part and help explain why people suffer vision loss in these eye diseases.
AMD Blindness May Be Avoidable With Anti-Cholesterol Drugs
http://mnt.to/a/4cHk
New research that links the causes of age-related macular degeneration (AMD) with clogged arteries suggests anti-cholesterol drugs may halt the eye disease, the leading cause of blindess among older people in the US.
Nonsurgical Option Shows Promise In Restoring Near Vision Without Glasses
http://mnt.to/a/4cFD
By middle age, most people have age-related declines in near vision (presbyopia) requiring bifocals or reading glasses. An emerging technique called hyperopic orthokeratology (OK) may provide a new alternative for restoring near vision without the need for glasses, according to a study, "Refractive Changes from Hyperopic Orthokeratology Monovision in Presbyopes", appearing in the April issue of Optometry and Vision Science, official journal of the American Academy of Optometry.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
New Test Kit Enables Effective Treatment For Newly Identified Deadly Lymphoma
http://mnt.to/a/4cFP
An international research team has identified a new type of deadly intestinal lymphoma that is particularly common in Asia. The team, led by clinician-scientists from the SingHealth Academic Healthcare Cluster, also developed a new diagnostic test to accurately identify these patients.
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** GENETICS News **
Fluorescent Tags Enable Observation Of Crucial Step In Human DNA Replication
http://mnt.to/a/4cGx
For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh Professor of Chemistry and Holder of the Eberly Family Chair in Chemistry at Penn State, the scientists "discovered how a key step in human DNA replication is performed.
ALS/FTD Neurodegeneration May Be Caused By 'RNA Sponge' Mechanism
http://mnt.to/a/4cGs
The most common genetic cause of both ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) was recently identified as an alteration in the gene C9orf72. But how the mutation causes neurodegenerative disease appeared mysterious.
How The Genetic Structure Of African Mosquitoes Is Evolving Has Implications For Controlling Malaria
http://mnt.to/a/4cFN
A surprising research discovery in mosquitoes could affect future prospects for malaria control. A team of scientists from West Africa, the United States and the United Kingdom found that the mosquito, Anopheles gambiae, which was thought to be splitting into two completely new species, may actually have a more complex range of forms due to frequent inter-mating.
Genetics Journal Highlights For April 2013
http://mnt.to/a/4cFM
Listed below are the selected highlights for the April 2013 issue of the Genetics Society of America's journal, Genetics. The April issue is available online.*ISSUE HIGHLIGHTSMethods, Technology and Resources1.
Novel Brain Cancer Treatment Uses Genetic Material From Bone Marrow Cells
http://mnt.to/a/4cFK
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of tumor.
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** HEART DISEASE News **
Body Mass Index (BMI) And Coronary Heart Disease
http://mnt.to/a/4cGT
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older.
Visiting Your Doctor Following ER Care For Chest Pain Reduces Risk Of Heart Attack, Death
http://mnt.to/a/4cGc
Seeing a doctor within a month of an emergency room visit for chest pain significantly reduced the risk of heart attack or death among high risk patients, according to research published the American Heart Association journal Circulation.
Risk For Coronary Heart Disease Increases With BMI
http://mnt.to/a/4cG9
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older.
Two Servings Of Fatty Fish Per Week Associated With Lower Risk Of Dying Among Older Adults
http://mnt.to/a/4cG8
Older adults who have higher levels of blood omega-3 levels - fatty acids found almost exclusively in fatty fish and seafood - may be able to lower their overall mortality risk by as much as 27% and their mortality risk from heart disease by about 35%, according to a new study from Harvard School of Public Health (HSPH) and the University of Washington.
Comparison Of 3 Water Pills For Heart Failure Finds The Most Effective May Be The Least Prescribed
http://mnt.to/a/4cG4
Loop diuretics, more commonly known as water pills, are the most widely prescribed heart failure medications, but few studies had extensively compared their effectiveness until Yale School of Medicine researchers examined three approved loop diuretics and found that even though one of them might offer more benefit, it is rarely prescribed.
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** IMMUNE SYSTEM / VACCINES News **
Using Virus' Ability To Evade The Immune System To 'Fortify' Adult Stem Cells
http://mnt.to/a/4cGw
Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their survival - with the goal of giving the cells time to exert their natural healing abilities.
Link Discovered Between Blood Clotting And Immune Response
http://mnt.to/a/4cGq
Rice University researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body's immune system. The find could lead to new treatments for thousands of patients who suffer from inflammatory diseases and disorders that cause abnormal blood clotting.
Researchers Discover How Cells Distinguish Friend From Foe
http://mnt.to/a/4cFQ
Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give themselves away by breaking into cells.
Fish Oil May Actually Enhance The Function Of B Cells
http://mnt.to/a/4cFG
Fish oil rich in DHA and EPA is widely believed to help prevent disease by reducing inflammation, but until now, scientists were not entirely sure about its immune enhancing effects. A new report appearing in the April 2013 issue of the Journal of Leukocyte Biology, helps provide clarity on this by showing that DHA-rich fish oil enhances B cell activity, a white blood cell, challenging the notion that fish oil is only immunosuppressive.
Discovery Of Immunity Protein That Ramps Up Inflammation - And Agents That Can Block It - Offers Potential To Improve Treatments For Pneumonia
http://mnt.to/a/4cFB
Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival and improved lung function in animal models of pneumonia.
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** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Polio To Be Eradicated By 2018
http://mnt.to/a/4cJy
The World Health Organization has stated that they aim to eradicate polio by the year 2018. Since 1988, when the Global Polio Eradication Initiative (GPEI) was launched, immunization efforts have significantly reduced the number of polio cases.
Target Meeting's 2nd World Virology & Microbiology Online Conference Held On April 16-18, 2013: Join For Free
http://mnt.to/a/4cHQ
A Free Virtual Virology & Microbiology Conference at Targetmeeting.com featuring 60 live presentations (12 sessions) from academic and industry experts around the world. Computer and internet connection are required.
Tonsillectomy Helps Adults Too
http://mnt.to/a/4cHc
Adults who undergo a tonsillectomy have fewer symptoms of pharyngitis, visit their doctors with throat problems less often, and miss work less, researchers from the University of Oulu and Oulu University Hospital, both in Finland, reported in CMAJ (Canadian Medical Association Journal).
Susceptibility To Some Viral Infections May Be Increased By Newly Approved Blood Thinner
http://mnt.to/a/4cGy
A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.
Discovery Of Immunity Protein That Ramps Up Inflammation - And Agents That Can Block It - Offers Potential To Improve Treatments For Pneumonia
http://mnt.to/a/4cFB
Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival and improved lung function in animal models of pneumonia.
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** LIVER DISEASE / HEPATITIS News **
New Drug Application Submitted To FDA For Simeprevir (TMC435) For Combination Treatment Of Adult Patients With Genotype 1 Chronic Hepatitis C
http://mnt.to/a/4cGZ
Filing Based on Phase 3 Data in Treatment-Naïve and Treatment-Experienced Patients with Compensated Liver DiseaseJanssen Research & Development, LLC (Janssen) today announced it has submitted a New Drug Application (NDA) to the U.
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** LUNG CANCER News **
Cisplatin-Resistant Cancer Cells Sensitive To Experimental Anticancer Drugs Called PARP Inhibitors
http://mnt.to/a/4cCX
Cisplatin-resistant non-small cell lung cancer cells expressed high levels of hyperactivated PARP1. Cells succumbed to PARP inhibitors in vitro. PARP inhibitor slowed cisplatin-resistant tumor growth in mice.
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** LUPUS News **
Link Discovered Between Blood Clotting And Immune Response
http://mnt.to/a/4cGq
Rice University researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body's immune system. The find could lead to new treatments for thousands of patients who suffer from inflammatory diseases and disorders that cause abnormal blood clotting.
----------------------------------------------
** LYMPHOMA / LEUKEMIA / MYELOMA News **
New Test Kit Enables Effective Treatment For Newly Identified Deadly Lymphoma
http://mnt.to/a/4cFP
An international research team has identified a new type of deadly intestinal lymphoma that is particularly common in Asia. The team, led by clinician-scientists from the SingHealth Academic Healthcare Cluster, also developed a new diagnostic test to accurately identify these patients.
----------------------------------------------
** MEDICAL DEVICES / DIAGNOSTICS News **
Imaging Technology Could Lower Coronary Disease Mortality Rate
http://mnt.to/a/4cH4
Patients undergoing angioplasty or other heart-related medical procedures could benefit from a new technology being developed with funding from the National Science Foundation (NSF).Optical imaging technology from Wasatch Photonics Inc.
Arrival Of Next-Generation Proton Therapy Tool Increases Precision, Expands Types Of Tumors That Can Be Treated At Illinois Center
http://mnt.to/a/4cH3
Pencil beam scanning boosts accuracy, further minimizes radiation delivered to healthy tissueOne of the most precise tools in the fight against cancer is now available to patients in the Midwest.
For-Profit Hospitals Outscore Public/Non-Profit On Performance Measures
http://mnt.to/a/4cGn
For-profit hospitals are outperforming other hospitals when treating stroke, heart attack and pneumonia patients in emergency departments and, thus, will be more likely to receive bonuses under Medicare's new payment rules, according to a new Northwestern Medicine® study.
New Test Kit Enables Effective Treatment For Newly Identified Deadly Lymphoma
http://mnt.to/a/4cFP
An international research team has identified a new type of deadly intestinal lymphoma that is particularly common in Asia. The team, led by clinician-scientists from the SingHealth Academic Healthcare Cluster, also developed a new diagnostic test to accurately identify these patients.
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** MEDICAL PRACTICE MANAGEMENT News **
Mortality Rates At Rural Hospitals Unusually High
http://mnt.to/a/4cJx
Death rates for medicare beneficiaries being treated at critical access hospitals in rural areas increased from 2002 to 2010, while rates in other hospitals fell, according to new research published in JAMA.
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** MEDICARE / MEDICAID / SCHIP News **
Mortality Rates At Rural Hospitals Unusually High
http://mnt.to/a/4cJx
Death rates for medicare beneficiaries being treated at critical access hospitals in rural areas increased from 2002 to 2010, while rates in other hospitals fell, according to new research published in JAMA.
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** MENTAL HEALTH News **
Should Suicidal Patients At Emergency Departments Be Asked About Gun Access?
http://mnt.to/a/4cFF
Although guns are used in over half of all American suicides, a new study shows that many emergency room doctors and nurses do not routinely ask suicidal patients about their access to firearms.
----------------------------------------------
** MRSA / DRUG RESISTANCE News **
Purdue-Developed Technology Could Provide A Solution To Antibiotic-Resistant Bacteria, Save Lives
http://mnt.to/a/4cGQ
Through the misuse and overuse of antibiotics, several types of bacteria have become resistant to drugs that were designed to kill them. The Centers for Disease Control and Prevention estimate that some of these "superbugs" are linked to tens of thousands of deaths in the United States annually, including 14,000 for C.
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** MUSCULAR DYSTROPHY / ALS News **
ALS/FTD Neurodegeneration May Be Caused By 'RNA Sponge' Mechanism
http://mnt.to/a/4cGs
The most common genetic cause of both ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) was recently identified as an alteration in the gene C9orf72. But how the mutation causes neurodegenerative disease appeared mysterious.
Muscle Regeneration Promoted In Mouse Model Of Muscular Dystrophy
http://mnt.to/a/4cGf
Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in the protein dystrophin. Dystrophin functions to protect muscle cells from injury and loss of functional dystrophin results in break down and loss of muscle cells.
Role Of Cells Other Than Motor Neurons Much Larger Than Anticipated In The Development Of Amyotrophic Lateral Sclerosis
http://mnt.to/a/4cFz
Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a fatal degenerative disease.
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** NEUROLOGY / NEUROSCIENCE News **
CABG Surgery Generally Not Associated With Long-Term Cognitive Dysfunction
http://mnt.to/a/4cGW
Nearly All Patients Recover Full Cognitive Function within 8 Weeks Post-SurgeryThe cognitive dysfunction observed in patients who undergo coronary artery bypass grafting (CABG) surgery usually disappears within 8 weeks following surgery, according to a study published in the April 2013 issue of The Annals of Thoracic Surgery.
Supplementation Of Alternative Fuels Could Protect The Brain During Hypoglycemia
http://mnt.to/a/4cGg
Tight control of blood glucose levels is critical to mitigating the long-term complications of diabetes; however, the intensive insulin therapy required for this control is frequently accompanied by recurrent episodes of low blood sugar (hypoglycemia).
Novel Brain Cancer Treatment Uses Genetic Material From Bone Marrow Cells
http://mnt.to/a/4cFK
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of tumor.
----------------------------------------------
** NUTRITION / DIET News **
"Health Halo Effect" Of Organic Labels
http://mnt.to/a/4cGG
The word "organic" can mean many things to consumers. Even so, the power of an organic label can be very strong: studies have shown that this simple label can lead us to think that a food is healthier, through what is known as the 'health halo effect'.
Two Servings Of Fatty Fish Per Week Associated With Lower Risk Of Dying Among Older Adults
http://mnt.to/a/4cG8
Older adults who have higher levels of blood omega-3 levels - fatty acids found almost exclusively in fatty fish and seafood - may be able to lower their overall mortality risk by as much as 27% and their mortality risk from heart disease by about 35%, according to a new study from Harvard School of Public Health (HSPH) and the University of Washington.
Fish Oil May Actually Enhance The Function Of B Cells
http://mnt.to/a/4cFG
Fish oil rich in DHA and EPA is widely believed to help prevent disease by reducing inflammation, but until now, scientists were not entirely sure about its immune enhancing effects. A new report appearing in the April 2013 issue of the Journal of Leukocyte Biology, helps provide clarity on this by showing that DHA-rich fish oil enhances B cell activity, a white blood cell, challenging the notion that fish oil is only immunosuppressive.
Guided Self-Help Found To Be Effective In Treating Childhood Obesity
http://mnt.to/a/4cFC
It is known that family-based treatment that combines nutrition and exercise education, along with behavior modification, is a good approach to help children lose weight. But clinic-based weight-control programs for childhood obesity are not accessible to many families, due to issues such as cost or time commitment.
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** OBESITY / WEIGHT LOSS / FITNESS News **
Direct Association Between Type 2 Diabetes And Obesity Found
http://mnt.to/a/4cHb
Obesity has been historically known as a risk factor for type 2 diabetes, and now a key mechanism has been found in the immune system that plays a part in the development of obesity-linked type 2 diabetes.
Body Mass Index (BMI) And Coronary Heart Disease
http://mnt.to/a/4cGT
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older.
Rewarding Healthy Behaviors In The Workplace
http://mnt.to/a/4cGd
Do cash rewards for healthier habits work? Maybe, says a new study, if you add on one more condition - peer pressure.A growing number of companies are offering employees an opportunity to boost earning power at work via cash incentives to stay healthy.
Risk For Coronary Heart Disease Increases With BMI
http://mnt.to/a/4cG9
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older.
Sildenafil Helps Turn 'Bad' White Adipose Tissue Into 'Good And Healthy' Brown Adipose Tissue
http://mnt.to/a/4cFJ
Although sildenafil is best known for promoting erections, it may also serve as a weight loss aid by coaxing our bodies to store more healthy "brown fat" relative to unhealthy "white fat" than it would otherwise do on its own.
Disrupting Our Internal Clocks May Lead To A Complete Absence Of 24-Hour Bodily Rhythms And An Immediate Gain In Body Weight
http://mnt.to/a/4cFH
If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. That's because new research published in The FASEB Journal used mice to show that proper sleep patterns are critical for healthy metabolic function, and even mild impairment in our circadian rhythms can lead to serious health consequences, including diabetes and obesity.
Guided Self-Help Found To Be Effective In Treating Childhood Obesity
http://mnt.to/a/4cFC
It is known that family-based treatment that combines nutrition and exercise education, along with behavior modification, is a good approach to help children lose weight. But clinic-based weight-control programs for childhood obesity are not accessible to many families, due to issues such as cost or time commitment.
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** PAIN / ANESTHETICS News **
Cymbalta Reduces Chemotherapy Induced Neuropathy
http://mnt.to/a/4cHd
Duloxetine, an antidepressant, was shown to reduce painful peripheral neuropathy caused by neurotoxic chemotherapy in a study published in JAMA. Researchers from the University of Michigan School of Nursing added that duloxetine benefited the majority of patients in their study.
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** PARKINSON'S DISEASE News **
Sorting Out The Structure Of A Parkinson's Protein
http://mnt.to/a/4cH2
Computer modeling may resolve conflicting results and offer hints for new drug-design strategies.Clumps of proteins that accumulate in brain cells are a hallmark of neurological diseases such as dementia, Parkinson's disease and Alzheimer's disease.
Model May Be Used To Develop Potential Treatment Strategies To Counteract Early Cellular Changes In Parkinson's Disease
http://mnt.to/a/4cGk
In a mouse model of early Parkinson's disease (PD), animals displayed movement deficits, loss of tyrosine-hydroxylase (TH)-positive fibers in the striatum, and astro-gliosis and micro-gliosis in the substantia nigra (SN), without the loss of nigral dopaminergic neurons.
Computer Modeling May Resolve Conflicting Results And Offer Hints For New Drug-Design Strategies For Parkinson's Disease
http://mnt.to/a/4cGj
Clumps of proteins that accumulate in brain cells are a hallmark of neurological diseases such as dementia, Parkinson's disease and Alzheimer's disease. Over the past several years, there has been much controversy over the structure of one of those proteins, known as alpha synuclein.
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** PEDIATRICS / CHILDREN'S HEALTH News **
One In 5 Teen Moms Who Gives Birth Already Has a Child
http://mnt.to/a/4cJw
Almost one in 5 teen moms who gives birth already has a child, according to the Centers for Disease Control and Prevention (CDC).Over 365,000 teenagers, ranging in age from 15 to 19 years, gave birth in 2010, and nearly 67,000 (18.
Guided Self-Help Found To Be Effective In Treating Childhood Obesity
http://mnt.to/a/4cFC
It is known that family-based treatment that combines nutrition and exercise education, along with behavior modification, is a good approach to help children lose weight. But clinic-based weight-control programs for childhood obesity are not accessible to many families, due to issues such as cost or time commitment.
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** PREGNANCY / OBSTETRICS News **
One In 5 Teen Moms Who Gives Birth Already Has a Child
http://mnt.to/a/4cJw
Almost one in 5 teen moms who gives birth already has a child, according to the Centers for Disease Control and Prevention (CDC).Over 365,000 teenagers, ranging in age from 15 to 19 years, gave birth in 2010, and nearly 67,000 (18.
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** PROSTATE / PROSTATE CANCER News **
Therapeutic Target For Prostate Cancer Provided By Newly Identified Tumor Suppressor
http://mnt.to/a/4cGv
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain of events that controls cell growth and metastasis, could lead to novel ways to control disease progression.
Delay Between Prostate Cancer Diagnosis And Treatment Longer For African Americans
http://mnt.to/a/4cGh
African American men on average wait a week longer than their Caucasian counterparts between the initial diagnosis of prostate cancer and treatment, according to University of North Carolina researchers.
Inhibiting SRC-3 Could Overcome The Cancer-Promoting Effects Of The Mutations In SPOP
http://mnt.to/a/4cG6
Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers led by those at Baylor College of Medicine in a report that appears online in Proceedings of the National Academy of Sciences.
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** PSYCHOLOGY / PSYCHIATRY News **
Men More Depressed Than Women If Childless
http://mnt.to/a/4cH9
Men are just as likely as women to want kids, and they feel more depressed, isolated, angry and sad than women if they are childless, according to a new study.The research was presented at the British Sociological Association yearly conference in London on April 3rd.
Single Fathers Due To Cancer: Unique Group Offers Support
http://mnt.to/a/4cGr
Men who have dependent children and whose spouses or partners died from cancer are an overlooked population. These fathers face unique challenges not addressed by traditional grief support groups that often attract an older, female population.
Increasing Compassionate Through Meditation
http://mnt.to/a/4cGm
Scientists have mostly focused on the benefits of meditation for the brain and the body, but a recent study by Northeastern University's David DeSteno, published in Psychological Science, takes a look at what impacts meditation has on interpersonal harmony and compassion.
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** PUBLIC HEALTH News **
Certain Kinds Of Household Air Pollution Can Be Deadly
http://mnt.to/a/4cGt
Almost four million people die each year from household air pollution (HAP) caused by exposure to the combustion of biomass fuels (wood, charcoal, crop residues, and dung), kerosene, or coal.
For-Profit Hospitals Outscore Public/Non-Profit On Performance Measures
http://mnt.to/a/4cGn
For-profit hospitals are outperforming other hospitals when treating stroke, heart attack and pneumonia patients in emergency departments and, thus, will be more likely to receive bonuses under Medicare's new payment rules, according to a new Northwestern Medicine® study.
How Much We Shrink With Age Influenced By Adult Health Habits
http://mnt.to/a/4cFL
Even if you didn't eat your veggies or drink your milk as a child, your height is still in your hands, reveal new findings by economists from the University of Southern California, Harvard University and Peking University.
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** RADIOLOGY / NUCLEAR MEDICINE News **
Arrival Of Next-Generation Proton Therapy Tool Increases Precision, Expands Types Of Tumors That Can Be Treated At Illinois Center
http://mnt.to/a/4cH3
Pencil beam scanning boosts accuracy, further minimizes radiation delivered to healthy tissueOne of the most precise tools in the fight against cancer is now available to patients in the Midwest.
Nuclear Medicine Enables Earlier COPD Diagnosis
http://mnt.to/a/4cGp
In vivo ventilation/perfusion (V/Q) imaging can detect early changes to the lung caused by cigarette smoke exposure and provides a noninvasive method for studying lung dysfunction in preclinical models, according to research published in the April issue of The Journal of Nuclear Medicine.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
New Drug Application Submitted To FDA For Simeprevir (TMC435) For Combination Treatment Of Adult Patients With Genotype 1 Chronic Hepatitis C
http://mnt.to/a/4cGZ
Filing Based on Phase 3 Data in Treatment-Naïve and Treatment-Experienced Patients with Compensated Liver DiseaseJanssen Research & Development, LLC (Janssen) today announced it has submitted a New Drug Application (NDA) to the U.
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** RESPIRATORY / ASTHMA News **
SMi Group Announce Vitalograph And Aerocrine As Sponsors Of Asthma & COPD
http://mnt.to/a/4cHR
SMi Group is pleased to announce Vitalograph and Aerocrine as sponsors of the 9th instalment in the Asthma series, taking place on 15th and 16th April, London."2013 is an exciting year for Vitalograph as we celebrate our 50th anniversary.
Tonsillectomy Helps Adults Too
http://mnt.to/a/4cHc
Adults who undergo a tonsillectomy have fewer symptoms of pharyngitis, visit their doctors with throat problems less often, and miss work less, researchers from the University of Oulu and Oulu University Hospital, both in Finland, reported in CMAJ (Canadian Medical Association Journal).
Breathing New Life Into Inhalers
http://mnt.to/a/4cGS
Development expertise of Cambridge Consultants leads to innovative new inhalerAn innovative dry powder inhaler (DPI) designed by product development firm Cambridge Consultants and Chiesi Farmaceutici has been launched onto the market.
Certain Kinds Of Household Air Pollution Can Be Deadly
http://mnt.to/a/4cGt
Almost four million people die each year from household air pollution (HAP) caused by exposure to the combustion of biomass fuels (wood, charcoal, crop residues, and dung), kerosene, or coal.
Discovery Of Immunity Protein That Ramps Up Inflammation - And Agents That Can Block It - Offers Potential To Improve Treatments For Pneumonia
http://mnt.to/a/4cFB
Scientists at the University of Pittsburgh School of Medicine have discovered a new biological pathway of innate immunity that ramps up inflammation and then identified agents that can block it, leading to increased survival and improved lung function in animal models of pneumonia.
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** SENIORS / AGING News **
Two Servings Of Fatty Fish Per Week Associated With Lower Risk Of Dying Among Older Adults
http://mnt.to/a/4cG8
Older adults who have higher levels of blood omega-3 levels - fatty acids found almost exclusively in fatty fish and seafood - may be able to lower their overall mortality risk by as much as 27% and their mortality risk from heart disease by about 35%, according to a new study from Harvard School of Public Health (HSPH) and the University of Washington.
Nonsurgical Option Shows Promise In Restoring Near Vision Without Glasses
http://mnt.to/a/4cFD
By middle age, most people have age-related declines in near vision (presbyopia) requiring bifocals or reading glasses. An emerging technique called hyperopic orthokeratology (OK) may provide a new alternative for restoring near vision without the need for glasses, according to a study, "Refractive Changes from Hyperopic Orthokeratology Monovision in Presbyopes", appearing in the April issue of Optometry and Vision Science, official journal of the American Academy of Optometry.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Disrupting Our Internal Clocks May Lead To A Complete Absence Of 24-Hour Bodily Rhythms And An Immediate Gain In Body Weight
http://mnt.to/a/4cFH
If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. That's because new research published in The FASEB Journal used mice to show that proper sleep patterns are critical for healthy metabolic function, and even mild impairment in our circadian rhythms can lead to serious health consequences, including diabetes and obesity.
----------------------------------------------
** SMOKING / QUIT SMOKING News **
Nuclear Medicine Enables Earlier COPD Diagnosis
http://mnt.to/a/4cGp
In vivo ventilation/perfusion (V/Q) imaging can detect early changes to the lung caused by cigarette smoke exposure and provides a noninvasive method for studying lung dysfunction in preclinical models, according to research published in the April issue of The Journal of Nuclear Medicine.
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** STATINS News **
Study Examines The Role Adverse Reactions Play In Statin Discontinuation
http://mnt.to/a/4cGb
Despite their well-documented benefits, statins, drugs used to lower cholesterol, are commonly discontinued in routine care. Statin discontinuation has been linked to increased risk for cardiovascular events and death in patients with coronary artery disease; nevertheless, the reasons for discontinuation are only starting to be explored.
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** STEM CELL RESEARCH News **
Using Virus' Ability To Evade The Immune System To 'Fortify' Adult Stem Cells
http://mnt.to/a/4cGw
Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their survival - with the goal of giving the cells time to exert their natural healing abilities.
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** TROPICAL DISEASES News **
How The Genetic Structure Of African Mosquitoes Is Evolving Has Implications For Controlling Malaria
http://mnt.to/a/4cFN
A surprising research discovery in mosquitoes could affect future prospects for malaria control. A team of scientists from West Africa, the United States and the United Kingdom found that the mosquito, Anopheles gambiae, which was thought to be splitting into two completely new species, may actually have a more complex range of forms due to frequent inter-mating.
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** UROLOGY / NEPHROLOGY News **
Protein In The Urine Linked To Life Expectancy
http://mnt.to/a/4cGY
Pee in a cup and you might get a clue as to how much longer you will live. A new report published online today in the National Kidney Foundation's American Journal of Kidney Diseases shows a strong correlation between levels of protein in the urine, or proteinuria, and mortality.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Risk For Coronary Heart Disease Increases With BMI
http://mnt.to/a/4cG9
Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight increases risk of CHD equivalent to that caused by getting older.
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