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** ALZHEIMER'S / DEMENTIA News **
Study Finds Similarity In Genes Associated With Alzheimer Disease Among African Americans And Individuals Of European Ancestry
http://mnt.to/a/4cMH
In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
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** ANXIETY / STRESS News **
How Stress Circuits Learn
http://mnt.to/a/4cN9
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including optogenetics, Jaideep Bains, PhD, and colleagues have shown stress circuits are capable of self-tuning following a single stress.
Soldiers Fighting In Unpopular Wars May Have Higher Risk Of Developing Post-Traumatic Stress Disorder When They Come Home
http://mnt.to/a/4cLT
Can events like Red Fridays, Tickets for Troops and the yellow ribbon campaign reduce the chances of Canadian soldiers experiencing combat-related stress disorders? The authors of a new study from the University of Alberta think so.
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** BIOLOGY / BIOCHEMISTRY News **
Size Does Matter: Women Find Large Penises More Attractive
http://mnt.to/a/4cPK
Finally the debate is over: size matters, and women prefer men with larger packages because it predicts a man's sex appeal, according to a new study in the journal Proceedings of the National Academy of Sciences (PNAS).
In Zebrafish Embryo, Retinoic Acid Gradient Visualized For The First Time
http://mnt.to/a/4cNb
In a ground-breaking study, researchers from the RIKEN Brain Science Institute in Japan report a new technique that allows them to visualize the distribution of retinoic acid in a live zebrafish embryo, in real-time.
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** BLOOD / HEMATOLOGY News **
Gene Underlies Vel Blood Group And Influences Red Blood Cell Traits, Will Lead To Safer Blood Transfusions
http://mnt.to/a/4cN7
Researchers have uncovered the gene at the root of a human blood group that has remained a mystery for the past 60 years. They showed that a genetic deletion on this gene is responsible for the lack of this blood group in some people.
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** BONES / ORTHOPEDICS News **
InVivo Therapeutics Receives Approval From FDA For First Human Trial Using Biomaterials For Traumatic Spinal Cord Injury
http://mnt.to/a/4cMV
InVivo Therapeutics Holdings Corp. (NVIV), a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI) and other neurotrauma conditions, today announced that the U.
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** BREAST CANCER News **
Patient Navigators Credited For High Rate Of Follow Up Following High-Risk Breast Cancer Screening
http://mnt.to/a/4cNj
Low-income and minority women screened for breast cancer at Capital Breast Cancer Center (CBCC) in Washington, DC, exceed national standards in their rate of medical follow-up after a positive mammogram, according to a small study presented at the American Association for Cancer Research Annual Meeting 2013.
Delayed Mammography Screening Can Increase Risk Of Breast Cancer Mortality
http://mnt.to/a/4cN5
The time between diagnosis of breast cancer among older women and their last mammogram is associated with a heightened risk of breast cancer mortality, according to new data presented at the American Association for Cancer Research (AACR) Annual Meeting 2013.
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** CANCER / ONCOLOGY News **
Delayed Mammography Screening Can Increase Risk Of Breast Cancer Mortality
http://mnt.to/a/4cN5
The time between diagnosis of breast cancer among older women and their last mammogram is associated with a heightened risk of breast cancer mortality, according to new data presented at the American Association for Cancer Research (AACR) Annual Meeting 2013.
First Mutations Leading To Leukemia Identified
http://mnt.to/a/4cN3
The first mutations leading to leukemia in the mother's womb have been identified, according to researchers who sequenced the entire genomes of identical twins with the disease.The experts conducted their study at The Institute of Cancer Research, London, and published their findings in the journal Proceedings of the National Academy of Sciences (PNAS).
Research Examines Association Between Genetic Mutation And Risk Of Death For Patients With Thyroid Cancer
http://mnt.to/a/4cML
Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association was not independent of tumor characteristics, how to use this information to manage mortality risk in patients with PTC is unclear, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
UCLA Researchers Link Auto Pollution Exposure And Some Childhood Cancers
http://mnt.to/a/4cMy
Researchers at UCLA's Fielding School of Public Health, led by Julia Heck, assistant researcher in the department of epidemiology and member of the Jonsson Comprehensive Cancer Center, have found a possible link between exposure to traffic-related air pollution and several childhood cancers.
Moving On From Traditional Biopsies, Blood Tests Found To Provide Fuller Picture Of Mutations In Cancer
http://mnt.to/a/4cLZ
A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators report at a special symposium of the American Association for Cancer Research annual meeting in Washington, April 6-10.
Mitochondrial Metabolic Regulator SIRT4 Guards Against DNA Damage
http://mnt.to/a/4cLW
Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.Researchers studying a set of proteins that regulate physiology, caloric restriction and aging have discovered another important role that one of them plays.
Promising New Minimally Invasive, MRI-Guided Laser Treatment For Recurrent Glioblastoma
http://mnt.to/a/4cLP
The first-in-human study of the NeuroBlate™ Thermal Therapy System finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma (GBM), a malignant type of brain tumor.
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** CARDIOVASCULAR / CARDIOLOGY News **
Genetic Variants Of Heart Disorder Discovered In Some Cases Of Stillbirth
http://mnt.to/a/4cMK
In a molecular genetic evaluation involving 91 cases of intrauterine fetal death, mutations associated with susceptibility to long QT syndrome (LQTS; a heart disorder that increases the risk for an irregular heartbeat and other adverse events) were discovered in a small number of these cases, preliminary evidence that may provide insights into the mechanism of some intrauterine fetal deaths, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
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** CLINICAL TRIALS / DRUG TRIALS News **
New Guidelines For Writing Abstracts Will Help Authors Summarise Their Research
http://mnt.to/a/4cMS
A new extension to the PRISMA guideline on reporting systemic reviews and meta-analyses (types of studies that analyse information from many studies) will help authors to give a more robust summary (abstract) of their study and is detailed by an international group of researchers in this week's PLOS Medicine.
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** COLORECTAL CANCER News **
Study Evaluates The Effectiveness Of Drugs For Colorectal Cancer In Animal Models More Relevant To Humans
http://mnt.to/a/4cNg
Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Once colorectal cancer has spread to other parts of the body, only 11 percent of patients will survive five years from the date of their diagnosis.
Virtual Colonoscopy Used Appropriately May Expand Screening To More Patients
http://mnt.to/a/4cLV
In 2009, the Centers for Medicare and Medicaid Services (CMS) halted reimbursement for so-called "virtual colonoscopy" for routine colon-cancer screening in asymptomatic patients, in part due to concerns over how this procedure, computed tomography colonography (CTC), was being used in the elderly population.
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** CROHN'S / IBD News **
Clinical Trial Finds Fecal Microbial Transplantation An Effective Treatment For Ulcerative Colitis
http://mnt.to/a/4cLX
A Spectrum Health clinical trial has found that fecal microbial transplantation (FMT) has resulted in the improvement or absence of symptoms in most pediatric patients with active ulcerative colitis.
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** DERMATOLOGY News **
Clues To Wound Healing Offered By Fruit Flies
http://mnt.to/a/4cLQ
A person's skin and a fruit fly's exoskeleton, called a "cuticle" may not look alike, but both coverings protect against injury, infection, and dehydration. The top layers of mammalian skin and insect cuticle are mesh-works of macromolecules, the mammal version consisting mostly of keratin proteins and the fly version predominantly of the carbohydrate chitin.
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** DIABETES News **
Muscle Metabolism And Diabetes
http://mnt.to/a/4cNd
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.In fact, the white muscle that increases with resistance training, age and diabetes helps keep blood sugar in check, the researchers showed.
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** EATING DISORDERS News **
Rewiring Appetite Control
http://mnt.to/a/4cLL
Researchers at the University of East Anglia (UEA) have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity.It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo's development in the womb and therefore their numbers were fixed for life.
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** ECZEMA / PSORIASIS News **
Clues To Wound Healing Offered By Fruit Flies
http://mnt.to/a/4cLQ
A person's skin and a fruit fly's exoskeleton, called a "cuticle" may not look alike, but both coverings protect against injury, infection, and dehydration. The top layers of mammalian skin and insect cuticle are mesh-works of macromolecules, the mammal version consisting mostly of keratin proteins and the fly version predominantly of the carbohydrate chitin.
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** ENDOCRINOLOGY News **
Artificial Ovary Offers More Natural Hormone Replacement
http://mnt.to/a/4cNH
Researchers in the US have bioengineered an artificial ovary that makes sex hormones in the same proportions as a healthy one. They report that in the lab setting at least, the bioengineered ovary shows sustained released of sex hormones estrogen and progesterone, and suggest it may provide a more natural option for women than hormone replacement therapy.
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** EYE HEALTH / BLINDNESS News **
Transcription Factors Identified That Regulate Retinal Vascularization
http://mnt.to/a/4cNk
The retina is a highly vascularized tissue, but too much or too little vascularization can lead to visual impairment and diseases such as familial exudative vitreoretinopathy or macular degeneration.
Researchers Identify New Vision Of How We Explore Our World
http://mnt.to/a/4cLS
Brain researchers at Barrow Neurological Institute have discovered that we explore the world with our eyes in a different way than previously thought. Their results advance our understanding of how healthy observers and neurological patients interact and glean critical information from the world around them.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Moving On From Traditional Biopsies, Blood Tests Found To Provide Fuller Picture Of Mutations In Cancer
http://mnt.to/a/4cLZ
A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators report at a special symposium of the American Association for Cancer Research annual meeting in Washington, April 6-10.
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** GENETICS News **
Mouse Model Used To Study Aging At The Molecular Level
http://mnt.to/a/4cNm
High fidelity DNA replication during each cycle of cell division is required to maintain genomic stability and prevent chromosomal mutations and rearrangements that can cause disease and aging.
Genome Wide Study Identifies Genetic Variants Associated With Childhood Obesity
http://mnt.to/a/4cN8
Researchers have identified four genes newly associated with severe childhood obesity. They also found an increased burden of rare structural variations in severely obese children.The team found that structural variations can delete sections of DNA that help to maintain protein receptors known to be involved in the regulation of weight.
Gene Underlies Vel Blood Group And Influences Red Blood Cell Traits, Will Lead To Safer Blood Transfusions
http://mnt.to/a/4cN7
Researchers have uncovered the gene at the root of a human blood group that has remained a mystery for the past 60 years. They showed that a genetic deletion on this gene is responsible for the lack of this blood group in some people.
First Mutations Leading To Leukemia Identified
http://mnt.to/a/4cN3
The first mutations leading to leukemia in the mother's womb have been identified, according to researchers who sequenced the entire genomes of identical twins with the disease.The experts conducted their study at The Institute of Cancer Research, London, and published their findings in the journal Proceedings of the National Academy of Sciences (PNAS).
Scientists Find That Prostate Cancer Patients With <i>BRCA2 </i>mutations Require Urgent Treatment
http://mnt.to/a/4cMT
Men who develop prostate cancer after inheriting a faulty gene need immediate surgery or radiotherapy rather than being placed under surveillance, as their disease is more aggressive than other types, a new study has found.
New Approaches To Molecular Diagnosis
http://mnt.to/a/4cMM
"Advances in understanding the molecular basis of rare and common disorders, as well as in the technology of DNA analysis, are rapidly changing the landscape of molecular genetic and genomic testing," writes Bruce R.
Research Examines Association Between Genetic Mutation And Risk Of Death For Patients With Thyroid Cancer
http://mnt.to/a/4cML
Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association was not independent of tumor characteristics, how to use this information to manage mortality risk in patients with PTC is unclear, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
Genetic Variants Of Heart Disorder Discovered In Some Cases Of Stillbirth
http://mnt.to/a/4cMK
In a molecular genetic evaluation involving 91 cases of intrauterine fetal death, mutations associated with susceptibility to long QT syndrome (LQTS; a heart disorder that increases the risk for an irregular heartbeat and other adverse events) were discovered in a small number of these cases, preliminary evidence that may provide insights into the mechanism of some intrauterine fetal deaths, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
Study Finds Similarity In Genes Associated With Alzheimer Disease Among African Americans And Individuals Of European Ancestry
http://mnt.to/a/4cMH
In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
The Epigenetic Effects Of Milk
http://mnt.to/a/4cM8
It seems the ads were right. A milk mustache is a good thing to have. Animal and dairy scientists have discovered that drinking milk at an early age can help mammals throughout their lives.But understanding exactly how milk affects the body is a complicated story of hormones, antibodies and proteins, as well as other cells and compounds researchers have not yet identified.
High Survival Rate In Liver Transplantation For Patients With Genetic Liver Conditions
http://mnt.to/a/4cM7
Journal of American College of Surgeons study reports that, despite the risks and the costs, liver transplant may also serve as a model for gene therapy through solid organ transplantation for some patients.
Mitochondrial Metabolic Regulator SIRT4 Guards Against DNA Damage
http://mnt.to/a/4cLW
Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.Researchers studying a set of proteins that regulate physiology, caloric restriction and aging have discovered another important role that one of them plays.
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** HIV / AIDS News **
Treatment Leads To Near-Normal Life Expectancy For People With HIV In South Africa
http://mnt.to/a/4cMQ
In South Africa, people with HIV who start treatment with anti-AIDS drugs (antiretroviral therapy) have life expectancies around 80% of that of the general population provided that they start treatment before their CD4 count drops below 200 (cells per microliter), according to a study by South African researchers published in this week's PLOS Medicine.
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** HYPERTENSION News **
WHO Raises Alarm About High Blood Pressure
http://mnt.to/a/4cMN
The World Health Organizations is raising the alarm about high blood pressure on World Health Day 2013. High blood pressure or hypertension kills nearly 1.5 million people every year in South-East Asia making it the single-most important risk factor for non communicable diseases like heart attack and stroke.
Rising Blood Pressure Rates Seen Across US Counties
http://mnt.to/a/4cLM
New data from the Institute for Health Metrics and Evaluation show variations among communities, genders and ethnic groups in treatment and control of high blood pressureOne in five Americans are completely unaware that they are at risk for the second leading cause of premature death: high blood pressure.
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** IMMUNE SYSTEM / VACCINES News **
Immune System Development Influenced By Birth Month
http://mnt.to/a/4cN4
Newborn babies' immune systems and vitamin D levels vary, depending on which month of the year they are born.These findings come from scientists at Queen Mary, University of London and the University of Oxford and were published in the journal JAMA Neurology.
Shingles Vaccine Is Associated With Reduction In Both Postherpetic Neuralgia And Herpes Zoster, But Uptake In The US Is Low
http://mnt.to/a/4cMR
A vaccine to prevent shingles may reduce by half the occurrence of this painful skin and nerve infection in older people (aged over 65 years) and may also reduce the rate of a painful complication of shingles, post-herpetic neuralgia, but has a very low uptake (only 4%) in older adults in the United States, according to a study by UK and US researchers published in this week's PLOS Medicine.
Host DNA Used By Vaccine Adjuvant To Boost Pathogen Recognition
http://mnt.to/a/4cM4
Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. No one knows, however, how they boost the immune response. In the March 19, 2013, issue of the Proceedings of the National Academy of Sciences researchers at National Jewish Health continue unraveling the mystery of adjuvants with a report that host DNA coats the alum adjuvant and induces two crucial cells to interact twice as long during the initial stimulation of the adaptive immune system.
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** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Genomics May Help Identify Organisms In Outbreaks Of Serious Infectious Disease Without Requiring Laboratory Culture
http://mnt.to/a/4cMJ
Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli (STEC) using metagenomics (the direct sequencing of DNA extracted from microbiologically complex samples), according to a study in the April 10 issue of JAMA, a Genomics theme issue.
Clinical Trial Finds Fecal Microbial Transplantation An Effective Treatment For Ulcerative Colitis
http://mnt.to/a/4cLX
A Spectrum Health clinical trial has found that fecal microbial transplantation (FMT) has resulted in the improvement or absence of symptoms in most pediatric patients with active ulcerative colitis.
Clues To Wound Healing Offered By Fruit Flies
http://mnt.to/a/4cLQ
A person's skin and a fruit fly's exoskeleton, called a "cuticle" may not look alike, but both coverings protect against injury, infection, and dehydration. The top layers of mammalian skin and insect cuticle are mesh-works of macromolecules, the mammal version consisting mostly of keratin proteins and the fly version predominantly of the carbohydrate chitin.
Diagnostic Achilles' Heel For Biothreat Detection In Highly Lethal Ebola Virus
http://mnt.to/a/4cLN
By screening a library of a billion llama antibodies on live Ebola viruses in the Texas Biomedical Research Institute's highest biocontainment laboratory, scientists in San Antonio have identified a potential weakness in the make-up of these deadly agents that can immediately yield a sensitive test.
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** LIVER DISEASE / HEPATITIS News **
High Survival Rate In Liver Transplantation For Patients With Genetic Liver Conditions
http://mnt.to/a/4cM7
Journal of American College of Surgeons study reports that, despite the risks and the costs, liver transplant may also serve as a model for gene therapy through solid organ transplantation for some patients.
----------------------------------------------
** LYMPHOMA / LEUKEMIA / MYELOMA News **
First Mutations Leading To Leukemia Identified
http://mnt.to/a/4cN3
The first mutations leading to leukemia in the mother's womb have been identified, according to researchers who sequenced the entire genomes of identical twins with the disease.The experts conducted their study at The Institute of Cancer Research, London, and published their findings in the journal Proceedings of the National Academy of Sciences (PNAS).
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** MEDICAL DEVICES / DIAGNOSTICS News **
Motor Skills Research Offers Potential Diagnostic Test
http://mnt.to/a/4cM5
People in their 20s don't have much on their middle-aged counterparts when it comes to some fine motor movements, researchers from UT Arlington have found.In a simple finger-tapping exercise, study participants' speed declined only slightly with age until a marked drop in ability with participants in their mid-60s.
Moving On From Traditional Biopsies, Blood Tests Found To Provide Fuller Picture Of Mutations In Cancer
http://mnt.to/a/4cLZ
A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators report at a special symposium of the American Association for Cancer Research annual meeting in Washington, April 6-10.
Promising New Minimally Invasive, MRI-Guided Laser Treatment For Recurrent Glioblastoma
http://mnt.to/a/4cLP
The first-in-human study of the NeuroBlate™ Thermal Therapy System finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma (GBM), a malignant type of brain tumor.
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** MEDICARE / MEDICAID / SCHIP News **
Virtual Colonoscopy Used Appropriately May Expand Screening To More Patients
http://mnt.to/a/4cLV
In 2009, the Centers for Medicare and Medicaid Services (CMS) halted reimbursement for so-called "virtual colonoscopy" for routine colon-cancer screening in asymptomatic patients, in part due to concerns over how this procedure, computed tomography colonography (CTC), was being used in the elderly population.
----------------------------------------------
** MELANOMA / SKIN CANCER News **
1 In 4 Melanoma Survivors Still Skips Sunscreen
http://mnt.to/a/4cN6
Results of a US survey presented at a conference on Monday suggest that as many as 27% of melanoma survivors still forego wearing sunscreen, while 2% continue to use tanning beds.Going out in the sun without protection and using indoor tanning beds are both known to increase the risk of developing melanoma, the most serious and life-threatening form of skin cancer.
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** MENTAL HEALTH News **
Soldiers Fighting In Unpopular Wars May Have Higher Risk Of Developing Post-Traumatic Stress Disorder When They Come Home
http://mnt.to/a/4cLT
Can events like Red Fridays, Tickets for Troops and the yellow ribbon campaign reduce the chances of Canadian soldiers experiencing combat-related stress disorders? The authors of a new study from the University of Alberta think so.
Suicide Risk, Gun Ownership, Political Conservatism And Church Membership
http://mnt.to/a/4cLR
Residents of states with the highest rates of gun ownership and political conservatism are at greater risk of suicide than those in states with less gun ownership and less politically conservative leanings, according to a study by University of California, Riverside sociology professor Augustine J.
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** MULTIPLE SCLEROSIS News **
Immune System Development Influenced By Birth Month
http://mnt.to/a/4cN4
Newborn babies' immune systems and vitamin D levels vary, depending on which month of the year they are born.These findings come from scientists at Queen Mary, University of London and the University of Oxford and were published in the journal JAMA Neurology.
----------------------------------------------
** NEUROLOGY / NEUROSCIENCE News **
How 'Free Will' Is Implemented In The Brain And Is It Possible To Intervene In The Process?
http://mnt.to/a/4cPy
Researchers have been able to identify the precise moment when a network of nerve cells (neurons) in the brain creates the signal to perform an action, before a person is even aware of deciding to take that action.
How Stress Circuits Learn
http://mnt.to/a/4cN9
Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including optogenetics, Jaideep Bains, PhD, and colleagues have shown stress circuits are capable of self-tuning following a single stress.
InVivo Therapeutics Receives Approval From FDA For First Human Trial Using Biomaterials For Traumatic Spinal Cord Injury
http://mnt.to/a/4cMV
InVivo Therapeutics Holdings Corp. (NVIV), a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI) and other neurotrauma conditions, today announced that the U.
Preventive Measures, Genetic Risks, New Diagnostic Tools Needed To Identify Effects Of Traumatic Brain Injury In Athletes, Soldiers
http://mnt.to/a/4cM6
One of the most controversial topics in neurology today is the prevalence of serious permanent brain damage after traumatic brain injury (TBI). Long-term studies and a search for genetic risk factors are required in order to predict an individual's risk for serious permanent brain damage, according to a review article published by Sam Gandy, MD, PhD, from the Icahn School of Medicine at Mount Sinai in a special issue of Nature Reviews Neurology dedicated to TBI.
Motor Skills Research Offers Potential Diagnostic Test
http://mnt.to/a/4cM5
People in their 20s don't have much on their middle-aged counterparts when it comes to some fine motor movements, researchers from UT Arlington have found.In a simple finger-tapping exercise, study participants' speed declined only slightly with age until a marked drop in ability with participants in their mid-60s.
Researchers Identify New Vision Of How We Explore Our World
http://mnt.to/a/4cLS
Brain researchers at Barrow Neurological Institute have discovered that we explore the world with our eyes in a different way than previously thought. Their results advance our understanding of how healthy observers and neurological patients interact and glean critical information from the world around them.
Promising New Minimally Invasive, MRI-Guided Laser Treatment For Recurrent Glioblastoma
http://mnt.to/a/4cLP
The first-in-human study of the NeuroBlate™ Thermal Therapy System finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma (GBM), a malignant type of brain tumor.
Rewiring Appetite Control
http://mnt.to/a/4cLL
Researchers at the University of East Anglia (UEA) have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity.It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo's development in the womb and therefore their numbers were fixed for life.
----------------------------------------------
** NUTRITION / DIET News **
The Epigenetic Effects Of Milk
http://mnt.to/a/4cM8
It seems the ads were right. A milk mustache is a good thing to have. Animal and dairy scientists have discovered that drinking milk at an early age can help mammals throughout their lives.But understanding exactly how milk affects the body is a complicated story of hormones, antibodies and proteins, as well as other cells and compounds researchers have not yet identified.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
Muscle Metabolism And Diabetes
http://mnt.to/a/4cNd
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.In fact, the white muscle that increases with resistance training, age and diabetes helps keep blood sugar in check, the researchers showed.
Genome Wide Study Identifies Genetic Variants Associated With Childhood Obesity
http://mnt.to/a/4cN8
Researchers have identified four genes newly associated with severe childhood obesity. They also found an increased burden of rare structural variations in severely obese children.The team found that structural variations can delete sections of DNA that help to maintain protein receptors known to be involved in the regulation of weight.
Rewiring Appetite Control
http://mnt.to/a/4cLL
Researchers at the University of East Anglia (UEA) have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity.It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo's development in the womb and therefore their numbers were fixed for life.
----------------------------------------------
** OVARIAN CANCER News **
Potential Novel Type Of Therapy For Ovarian Cancer
http://mnt.to/a/4cM2
A new antibody-guided drug has shown promising activity in a phase I trial involving ovarian cancer patients with platinum drug-resistant disease, researchers from Dana-Farber Cancer Institute reported at the annual meeting of the American Association for Cancer Research.
Promising Results For 2-Step Ovarian Cancer Immunotherapy Made From Patients' Own Tumor
http://mnt.to/a/4cLY
As many as three quarters of advanced ovarian cancer patients appeared to respond to a new two-step immunotherapy approach -- including one patient who achieved complete remission -- according research from the Perelman School of Medicine at the University of Pennsylvania that was presented in a press conference at the AACR Annual Meeting 2013 (Presentation #LB-335).
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** PAIN / ANESTHETICS News **
News From Annals Of Internal Medicine: Apr. 9 2013
http://mnt.to/a/4cNh
1. American College of Physicians Releases Recommendations for Prostate Cancer Screening: Shared Decision-Making, Clear Patient Preference Recommended Before PSA TestingMen between the ages of 50 and 69 should discuss the limited benefits and substantial harms of the prostate-specific antigen (PSA) test with their doctor before undergoing screening for prostate cancer, according to new recommendations by the American College of Physicians (ACP).
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** PARKINSON'S DISEASE News **
Mannitol Offers Sweet Future For Parkinson's Disease
http://mnt.to/a/4cM3
Researchers from Tel Aviv University describe experiments that could lead to a new approach for treating Parkinson's disease (PD) using a common sweetener, mannitol. This research was presented at the Genetics Society of America's 54th Annual Drosophila Research Conference in Washington D.
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** PEDIATRICS / CHILDREN'S HEALTH News **
Genome Wide Study Identifies Genetic Variants Associated With Childhood Obesity
http://mnt.to/a/4cN8
Researchers have identified four genes newly associated with severe childhood obesity. They also found an increased burden of rare structural variations in severely obese children.The team found that structural variations can delete sections of DNA that help to maintain protein receptors known to be involved in the regulation of weight.
UCLA Researchers Link Auto Pollution Exposure And Some Childhood Cancers
http://mnt.to/a/4cMy
Researchers at UCLA's Fielding School of Public Health, led by Julia Heck, assistant researcher in the department of epidemiology and member of the Jonsson Comprehensive Cancer Center, have found a possible link between exposure to traffic-related air pollution and several childhood cancers.
Clinical Trial Finds Fecal Microbial Transplantation An Effective Treatment For Ulcerative Colitis
http://mnt.to/a/4cLX
A Spectrum Health clinical trial has found that fecal microbial transplantation (FMT) has resulted in the improvement or absence of symptoms in most pediatric patients with active ulcerative colitis.
----------------------------------------------
** PREGNANCY / OBSTETRICS News **
Morning Sickness Drug "Diclegis" Approved By The FDA
http://mnt.to/a/4cPJ
Diclegis (doxylamine succinate and pyridoxine hydrochloride) has just been approved by the U.S. Food and Drug Administration (FDA) for the treatment of nausea and vomiting, commonly known as "morning sickness", among pregnant women.
Immune System Development Influenced By Birth Month
http://mnt.to/a/4cN4
Newborn babies' immune systems and vitamin D levels vary, depending on which month of the year they are born.These findings come from scientists at Queen Mary, University of London and the University of Oxford and were published in the journal JAMA Neurology.
Genetic Variants Of Heart Disorder Discovered In Some Cases Of Stillbirth
http://mnt.to/a/4cMK
In a molecular genetic evaluation involving 91 cases of intrauterine fetal death, mutations associated with susceptibility to long QT syndrome (LQTS; a heart disorder that increases the risk for an irregular heartbeat and other adverse events) were discovered in a small number of these cases, preliminary evidence that may provide insights into the mechanism of some intrauterine fetal deaths, according to a study in the April 10 issue of JAMA, a Genomics theme issue.
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** PROSTATE / PROSTATE CANCER News **
News From Annals Of Internal Medicine: Apr. 9 2013
http://mnt.to/a/4cNh
1. American College of Physicians Releases Recommendations for Prostate Cancer Screening: Shared Decision-Making, Clear Patient Preference Recommended Before PSA TestingMen between the ages of 50 and 69 should discuss the limited benefits and substantial harms of the prostate-specific antigen (PSA) test with their doctor before undergoing screening for prostate cancer, according to new recommendations by the American College of Physicians (ACP).
Scientists Find That Prostate Cancer Patients With <i>BRCA2 </i>mutations Require Urgent Treatment
http://mnt.to/a/4cMT
Men who develop prostate cancer after inheriting a faulty gene need immediate surgery or radiotherapy rather than being placed under surveillance, as their disease is more aggressive than other types, a new study has found.
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** PSYCHOLOGY / PSYCHIATRY News **
Size Does Matter: Women Find Large Penises More Attractive
http://mnt.to/a/4cPK
Finally the debate is over: size matters, and women prefer men with larger packages because it predicts a man's sex appeal, according to a new study in the journal Proceedings of the National Academy of Sciences (PNAS).
Suicide Risk, Gun Ownership, Political Conservatism And Church Membership
http://mnt.to/a/4cLR
Residents of states with the highest rates of gun ownership and political conservatism are at greater risk of suicide than those in states with less gun ownership and less politically conservative leanings, according to a study by University of California, Riverside sociology professor Augustine J.
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** PUBLIC HEALTH News **
Testing The Environmental And Health Effects Of Nanoparticles
http://mnt.to/a/4cNn
Earlier efforts to determine the health and environmental effects of the nanoparticles that are finding use in hundreds of consumer products may have produced misleading results by embracing traditional toxicology tests that do not take into account the unique properties of bits of material so small that 100,000 could fit in the period at the end of this sentence.
Suicide Risk, Gun Ownership, Political Conservatism And Church Membership
http://mnt.to/a/4cLR
Residents of states with the highest rates of gun ownership and political conservatism are at greater risk of suicide than those in states with less gun ownership and less politically conservative leanings, according to a study by University of California, Riverside sociology professor Augustine J.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
InVivo Therapeutics Receives Approval From FDA For First Human Trial Using Biomaterials For Traumatic Spinal Cord Injury
http://mnt.to/a/4cMV
InVivo Therapeutics Holdings Corp. (NVIV), a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI) and other neurotrauma conditions, today announced that the U.
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** SENIORS / AGING News **
Mouse Model Used To Study Aging At The Molecular Level
http://mnt.to/a/4cNm
High fidelity DNA replication during each cycle of cell division is required to maintain genomic stability and prevent chromosomal mutations and rearrangements that can cause disease and aging.
Transcription Factors Identified That Regulate Retinal Vascularization
http://mnt.to/a/4cNk
The retina is a highly vascularized tissue, but too much or too little vascularization can lead to visual impairment and diseases such as familial exudative vitreoretinopathy or macular degeneration.
Motor Skills Research Offers Potential Diagnostic Test
http://mnt.to/a/4cM5
People in their 20s don't have much on their middle-aged counterparts when it comes to some fine motor movements, researchers from UT Arlington have found.In a simple finger-tapping exercise, study participants' speed declined only slightly with age until a marked drop in ability with participants in their mid-60s.
Virtual Colonoscopy Used Appropriately May Expand Screening To More Patients
http://mnt.to/a/4cLV
In 2009, the Centers for Medicare and Medicaid Services (CMS) halted reimbursement for so-called "virtual colonoscopy" for routine colon-cancer screening in asymptomatic patients, in part due to concerns over how this procedure, computed tomography colonography (CTC), was being used in the elderly population.
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** SEXUAL HEALTH / STDS News **
Size Does Matter: Women Find Large Penises More Attractive
http://mnt.to/a/4cPK
Finally the debate is over: size matters, and women prefer men with larger packages because it predicts a man's sex appeal, according to a new study in the journal Proceedings of the National Academy of Sciences (PNAS).
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** SMOKING / QUIT SMOKING News **
Walking For 20 Minutes A Day Can Help Teens Quit Smoking
http://mnt.to/a/4cPL
Walking for just 20 minutes a day can help teenage smokers cut down on their smoking habit.Teens are even more likely to quit altogether if they participate in a smoking cessation/fitness program and increase the days on which they get at least 30 minutes of exercise.
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** SPORTS MEDICINE / FITNESS News **
Walking For 20 Minutes A Day Can Help Teens Quit Smoking
http://mnt.to/a/4cPL
Walking for just 20 minutes a day can help teenage smokers cut down on their smoking habit.Teens are even more likely to quit altogether if they participate in a smoking cessation/fitness program and increase the days on which they get at least 30 minutes of exercise.
Muscle Metabolism And Diabetes
http://mnt.to/a/4cNd
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.In fact, the white muscle that increases with resistance training, age and diabetes helps keep blood sugar in check, the researchers showed.
Preventive Measures, Genetic Risks, New Diagnostic Tools Needed To Identify Effects Of Traumatic Brain Injury In Athletes, Soldiers
http://mnt.to/a/4cM6
One of the most controversial topics in neurology today is the prevalence of serious permanent brain damage after traumatic brain injury (TBI). Long-term studies and a search for genetic risk factors are required in order to predict an individual's risk for serious permanent brain damage, according to a review article published by Sam Gandy, MD, PhD, from the Icahn School of Medicine at Mount Sinai in a special issue of Nature Reviews Neurology dedicated to TBI.
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** STEM CELL RESEARCH News **
Sticky Signature: Separation Of Stem Cells Enabled By Adhesive Force Differences
http://mnt.to/a/4cNc
A new separation process that depends on an easily-distinguished physical difference in adhesive forces among cells could help expand production of stem cells generated through cell reprogramming.
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** TRANSPLANTS / ORGAN DONATIONS News **
High Survival Rate In Liver Transplantation For Patients With Genetic Liver Conditions
http://mnt.to/a/4cM7
Journal of American College of Surgeons study reports that, despite the risks and the costs, liver transplant may also serve as a model for gene therapy through solid organ transplantation for some patients.
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** TROPICAL DISEASES News **
Worldwide The Burden Of Dengue Is Triple Current Estimates
http://mnt.to/a/4cNf
The global burden of dengue infection is more than triple current estimates from the World Health Organization, according to a multinational study published in the journal Nature.The research has created the first detailed and up-to-date map of dengue distribution worldwide, enabling researchers to estimate the total numbers of people affected by the virus globally, regionally and nationally.
Diagnostic Achilles' Heel For Biothreat Detection In Highly Lethal Ebola Virus
http://mnt.to/a/4cLN
By screening a library of a billion llama antibodies on live Ebola viruses in the Texas Biomedical Research Institute's highest biocontainment laboratory, scientists in San Antonio have identified a potential weakness in the make-up of these deadly agents that can immediately yield a sensitive test.
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** VASCULAR News **
Edema Inhibitor Identified By MDC And FMP Researchers
http://mnt.to/a/4cMP
Researchers of the Max Delbrück Center for Molecular Medicine (MDC) and the Leibniz Institute of Molecular Pharmacology (FMP) in Berlin-Buch, Germany, have now detected a substance that can prevent the accumulation of fluid in body tissue and thus edema formation.
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** VETERANS / EX-SERVICEMEN News **
Preventive Measures, Genetic Risks, New Diagnostic Tools Needed To Identify Effects Of Traumatic Brain Injury In Athletes, Soldiers
http://mnt.to/a/4cM6
One of the most controversial topics in neurology today is the prevalence of serious permanent brain damage after traumatic brain injury (TBI). Long-term studies and a search for genetic risk factors are required in order to predict an individual's risk for serious permanent brain damage, according to a review article published by Sam Gandy, MD, PhD, from the Icahn School of Medicine at Mount Sinai in a special issue of Nature Reviews Neurology dedicated to TBI.
Soldiers Fighting In Unpopular Wars May Have Higher Risk Of Developing Post-Traumatic Stress Disorder When They Come Home
http://mnt.to/a/4cLT
Can events like Red Fridays, Tickets for Troops and the yellow ribbon campaign reduce the chances of Canadian soldiers experiencing combat-related stress disorders? The authors of a new study from the University of Alberta think so.
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** WATER - AIR QUALITY / AGRICULTURE News **
UCLA Researchers Link Auto Pollution Exposure And Some Childhood Cancers
http://mnt.to/a/4cMy
Researchers at UCLA's Fielding School of Public Health, led by Julia Heck, assistant researcher in the department of epidemiology and member of the Jonsson Comprehensive Cancer Center, have found a possible link between exposure to traffic-related air pollution and several childhood cancers.
The Epigenetic Effects Of Milk
http://mnt.to/a/4cM8
It seems the ads were right. A milk mustache is a good thing to have. Animal and dairy scientists have discovered that drinking milk at an early age can help mammals throughout their lives.But understanding exactly how milk affects the body is a complicated story of hormones, antibodies and proteins, as well as other cells and compounds researchers have not yet identified.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Artificial Ovary Offers More Natural Hormone Replacement
http://mnt.to/a/4cNH
Researchers in the US have bioengineered an artificial ovary that makes sex hormones in the same proportions as a healthy one. They report that in the lab setting at least, the bioengineered ovary shows sustained released of sex hormones estrogen and progesterone, and suggest it may provide a more natural option for women than hormone replacement therapy.
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