FDA approved trametinib (MEKINIST tablet, GlaxoSmithKline, LLC), for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutation as detected by an FDA-approved test. May 29, 2013. More Information: http://www.fda.gov/Drugs/InformationOnDrugs/ApprovedDrugs/ucm354478.htm