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BreakThrough Digest Medical News

BreakThrough Digest Medical News


New research shows cheese may prevent cavities

Posted: 04 Jun 2013 09:00 PM PDT

Consuming dairy products is vital to maintaining good overall health, and it’s especially important to bone health. But there has been little research about how dairy products affect oral health in particular. However, according to a new study published in the May/June 2013 issue of General Dentistry, the peer-reviewed clinical journal of the Academy of General Dentistry (AGD), consuming cheese and other dairy products may help protect teeth against cavities.

The study sampled 68 subjects ranging in age from 12 to 15, and the authors looked at the dental plaque pH in the subjects’ mouths before and after they consumed cheese, milk, or sugar-free yogurt. A pH level lower than 5.5 puts a person at risk for tooth erosion, which is a process that wears away the enamel (or protective outside layer) of teeth. “The higher the pH level is above 5.5, the lower the chance of developing cavities,” explains Vipul Yadav, MDS, lead author of the study.

The subjects were assigned into groups randomly. Researchers instructed the first group to eat cheddar cheese, the second group to drink milk, and the third group to eat sugar-free yogurt. Each group consumed their product for three minutes and then swished with water. Researchers measured the pH level of each subject’s mouth at 10, 20, and 30 minutes after consumption.

The groups who consumed milk and sugar-free yogurt experienced no changes in the pH levels in their mouths. Subjects who ate cheese, however, showed a rapid increase in pH levels at each time interval, suggesting that cheese has anti-cavity properties.

The study indicated that the rising pH levels from eating cheese may have occurred due to increased saliva production (the mouth’s natural way to maintain a baseline acidity level), which could be caused by the action of chewing. Additionally, various compounds found in cheese may adhere to tooth enamel and help further protect teeth from acid.

“It looks like dairy does the mouth good,” says AGD spokesperson Seung-Hee Rhee, DDS, FAGD. “Not only are dairy products a healthy alternative to carb- or sugar-filled snacks, they also may be considered as a preventive measure against cavities.”

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KnowYourTeeth.com is the Academy of General Dentistry’s (AGD) source of consumer information on dental care and oral health. Its goal is to provide reliable information in a format that is easy to use and navigate, and to provide the tools that will help consumers of all ages to care for their teeth and with other aspects of oral care. KnowYourTeeth.com answers important dental health questions, offers the latest information on current dental treatments and tips for first-rate oral hygiene, and can help visitors find qualified dentists near where they live or work.

About the Academy of General Dentistry

 

The Academy of General Dentistry (AGD) is a professional association of more than 38,000 general dentists dedicated to providing quality dental care and oral health education to the public. AGD members stay up-to-date in their profession through a commitment to continuing education. Founded in 1952, the AGD is the second largest dental association in the United States, and it is the only association that exclusively represents the needs and interests of general dentists. A general dentist is the primary care provider for patients of all ages and is responsible for the diagnosis, treatment, management, and overall coordination of services related to patients’ oral health needs. For more information about the AGD, visit agd.org. The AGD is a member of the Partnership for Healthy Mouths, Healthy Lives, a first-of-its-kind national dental coalition composed of 35 leading dental health organizations. The Partnership’s campaign is designed to educate parents and caregivers on how to improve their children’s oral health in simple ways. The campaign offers families oral health resources through the website 2min2x.org.

Contact: Lauren Henderson
media@agd.org
312-440-4974
Academy of General Dentistry

Treatment helps sex stage a comeback after menopause

Posted: 04 Jun 2013 09:00 PM PDT

A satisfying sex life is an important contributor to older adults’ quality of life, but the sexual pain that can come after menopause can rob women and their partners of that satisfaction. Treatment can help restore it, shows a global survey including some 1,000 middle-aged North American men and women, published online today in Menopause, the journal of The North American Menopause Society (NAMS).

Sexual pain at this stage in a woman’s life is usually the result of the typical drying and thinning of tissues in and around the vagina after menopause, called vulvovaginal atrophy (VVA), coupled with a decrease in sexual activity. Vaginal lubricants and moisturizers, vaginal estrogen, and ospemifene, a recently approved oral drug that is a selective estrogen receptor modulator (SERM), can all be used to treat it.

Known as Clarifying Vaginal Atrophy’s Impact on Sex and Relationships (CLOSER), the survey was commissioned by Novo Nordisk, the maker of a vaginal estrogen treatment. It included postmenopausal women volunteers age 55 to 65 who had VVA and their male partners. This part of CLOSER looked at how treatment with vaginal estrogen affected their sex lives.

Before treatment, a majority of these women (58%) said they had been avoiding intimacy because of the pain, and 68% said they had lost their desire because of it. An even higher percentage of the men (78%) thought their partner’s vaginal discomfort caused them to avoid intimacy. About a third of the men and women had stopped having sex altogether.

After treatment, a majority of women and men reported sex was less painful for them and their partner, and more than 40% of the women and men said sex was more satisfying. Twenty-nine percent of the women and 34% of the men said their sex life had improved. Treatment also had a positive impact on the women’s self esteem. About a third felt more optimistic about the future of their sex life, and a similar number felt more connected to their partners.

“There is no need for a woman’s quality of life to decline because of VVA,” said NAMS Executive Director Margery L.S. Gass, MD.

Many women get relief with vaginal lubricants and moisturizers and regular sexual activity or the use of vaginal dilators. Vaginal estrogen, in the form of creams, tablets, or rings, is a common therapy and is appealing for women who cannot or choose not to take oral hormones, since absorption into the bloodstream is minimal. Women who have had breast or uterine cancer are encouraged to discuss the pros and cons of different treatments with their oncologist. The SERM offers an alternative for women who choose not to use any oral or vaginal hormone therapy.

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The article, “Clarifying Vaginal Atrophy’s Impact on Sex and Relationships (CLOSER) survey: emotional and physical impact of vaginal discomfort on North American postmenopausal women and their partners,” will be published in the February 2014 print edition of Menopause.

Founded in 1989, The North American Menopause Society (NAMS) is North America’s leading nonprofit organization dedicated to promoting the health and quality of life of all women during midlife and beyond through an understanding of menopause and healthy aging. Its multidisciplinary membership of 2,000 leaders in the field?including clinical and basic science experts from medicine, nursing, sociology, psychology, nutrition, anthropology, epidemiology, pharmacy, and education?makes NAMS uniquely qualified to serve as the definitive resource for health professionals and the public for accurate, unbiased information about menopause and healthy aging. To learn more about NAMS, visit our website: http://www.menopause.org

Contact: Eileen Petridis
epetridis@fallscommunications.com
216-696-0229
The North American Menopause Society (NAMS)

First dual-action compound kills cancer cells, stops them from spreading

Posted: 04 Jun 2013 09:00 PM PDT

Scientists are reporting development and successful lab tests on the first potential drug to pack a lethal one-two punch against melanoma skin cancer cells. Hit number one destroys cells in the main tumor, and the second hit blocks the spread of the cancer to other sites in the body, according to their report in the journal ACS Chemical Biology.

Nathan Luedtke and colleagues explain that the spread of melanoma and other forms of cancer beyond the original location ? a process called metastasis ? makes cancer such a serious disease. Photodynamic therapy (PDT), which involves administering a drug that kills cancer cells when exposed to light, already is available. But PDT works only on the main tumor and has other drawbacks. Luedtke’s team set out to find an improved approach to PDT.

The scientists describe successful tests in laboratory mice of one compound they synthesized that not only killed melanoma cells, but also stopped them from metastasizing by blocking a key signal inside the tumor cells. The compound “provides the first example of a preclinical candidate possessing both of these properties,” the scientists state.

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The authors acknowledge funding from the Swiss National Science Foundation.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world’s largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society