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** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **
Alcohol-related violence dependent on drinking 'context'
http://mnt.to/a/4gZ7
Although a high volume and frequency of drinking has been linked to an increase in violence toward a loved one, new research suggests that the context in which drinking occurs can play a role in violence against partners.
NIDA updates its consumer treatment guide in recognition of National Recovery Month
http://mnt.to/a/4gZ5
People seeking addiction treatment for themselves or loved ones will now have an updated resource with questions they should ask potential treatment centers. The revised consumer guide, Seeking Drug Abuse Treatment: Know What to Ask, is evidence-based and is being released in recognition of this year's National Recovery Month.
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** ANXIETY / STRESS News **
Fighting fears possible during sleep, study shows
http://mnt.to/a/4gZ2
For many patients with phobias, typical treatment involves gradual exposure to the feared object or situation. But researchers have now found that emotional memory can be manipulated during sleep, paving the way to new phobia treatments as we dream.
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** ARTHRITIS / RHEUMATOLOGY News **
UCB receives CHMP positive opinion for Cimzia® (certolizumab pegol) in severe active axial spondyloarthritis
http://mnt.to/a/4gZ9
UCB has announced that the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending extending the European Union marketing authorization for the use of Cimzia® (certolizumab pegol) in the treatment of adult patients with severe active axial spondyloarthritis (axSpA).
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** ASBESTOS / MESOTHELIOMA News **
Leicester leads two groundbreaking trials into treatments for asbestos-related cancer
http://mnt.to/a/4gZj
University of Leicester researchers are leading two major trials into treatments for a type of cancer which affects those exposed to asbestos. Professor Dean Fennell, of the University's Department of Cancer Studies and Molecular Medicine, is leading two groundbreaking trials into mesothelioma - a form of lung cancer strongly linked with exposure to asbestos.
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** AUTISM News **
How brain cell connections get cemented early in life could aid understanding of autism, schizophrenia, intellectual disability
http://mnt.to/a/4gYD
When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses.But as we grow and learn, things get a bit more stable.
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** BACK PAIN News **
UCB receives CHMP positive opinion for Cimzia® (certolizumab pegol) in severe active axial spondyloarthritis
http://mnt.to/a/4gZ9
UCB has announced that the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending extending the European Union marketing authorization for the use of Cimzia® (certolizumab pegol) in the treatment of adult patients with severe active axial spondyloarthritis (axSpA).
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** BONES / ORTHOPEDICS News **
UCB receives CHMP positive opinion for Cimzia® (certolizumab pegol) in severe active axial spondyloarthritis
http://mnt.to/a/4gZ9
UCB has announced that the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending extending the European Union marketing authorization for the use of Cimzia® (certolizumab pegol) in the treatment of adult patients with severe active axial spondyloarthritis (axSpA).
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** CANCER / ONCOLOGY News **
Married cancer patients 'likely to live longer'
http://mnt.to/a/4gZP
People who are married when they are diagnosed with cancer are more likely to live longer, compared with those who are unmarried. This is according to a new study published in the Journal of Clinical Oncology.
Accurately identifying neck tumors using robotics improves treatment, survival, Pitt study finds
http://mnt.to/a/4gZf
Using robotic surgery done through the mouth to more accurately identify the cause of lumps in the neck can help physicians to better target more personalized therapies for patients and dramatically improve survival, according to a study led by the University of Pittsburgh's Umamaheswar Duvvuri, M.
EU Parliament unites with patient and professional organisations to fight head and neck cancer: Action urgently needed to improve patient outcomes
http://mnt.to/a/4gZ8
On September 24th the European Head and Neck Society (EHNS) and the European Cancer Patient Coalition (ECPC) will join forces with the European Parliament to highlight the challenges in treating head and neck cancer.
New method for analyzing gene expression in single cells opens window into tumors and other tissues
http://mnt.to/a/4gYS
A team of researchers affiliated with Ludwig Cancer Research and the Karolinska Institutet in Sweden report in the current issue of Nature Methods a dramatically improved technique for analyzing the genes expressed within a single cell -- a capability of relevance to everything from basic research to future cancer diagnostics.
Protein that regulates cellular trafficking offers potential for anti-cancer therapy
http://mnt.to/a/4gYQ
Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases.
A clear look at a crucial step in cancer metastasis
http://mnt.to/a/4gYC
Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor.
Switch identified that controls growth of most aggressive brain tumor cells
http://mnt.to/a/4gYz
Researchers at UT Southwestern Medical Center have identified a cellular switch that potentially can be turned off and on to slow down, and eventually inhibit the growth of the most commonly diagnosed and aggressive malignant brain tumor.
Dog food preservative may thwart pain and damage of peripheral neuropathy
http://mnt.to/a/4gXZ
Working with cells in test tubes and in mice, researchers at Johns Hopkins have discovered that a chemical commonly used as a dog food preservative may prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.
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** CARDIOVASCULAR / CARDIOLOGY News **
Lives of patients with acute heart attack saved by blood pressure cuff
http://mnt.to/a/4gYm
In patients with an acute heart attack, remote ischemic conditioning - intermittent inflation of a blood pressure cuff to cut off blood flow to the arm during transportation to hospital for acute balloon dilatation - reduces subsequent cardiac symptoms and mortality after acute heart attack.
Heart disease patients benefit from high intensity training
http://mnt.to/a/4gYk
High-intensity exercise is shown to be protective against coronary heart disease (CHD) and is well known as a popular and time-saving approach to getting fit. But what about people who already have heart disease? Previously, these patients were told to exercise, but only at a moderate intensity to protect their hearts.
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** CHOLESTEROL News **
Statin use may raise cataract risk
http://mnt.to/a/4gYG
New research suggests that use of statins, a class of drugs taken by millions of Americans with high cholesterol, is linked to a higher risk for developing cataracts.Dr. Jessica Leuschen, of the San Antonio Military Medical Center, Texas, and colleagues report their findings in a paper published online in JAMA Ophthalmology.
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** CLINICAL TRIALS / DRUG TRIALS News **
Leicester leads two groundbreaking trials into treatments for asbestos-related cancer
http://mnt.to/a/4gZj
University of Leicester researchers are leading two major trials into treatments for a type of cancer which affects those exposed to asbestos. Professor Dean Fennell, of the University's Department of Cancer Studies and Molecular Medicine, is leading two groundbreaking trials into mesothelioma - a form of lung cancer strongly linked with exposure to asbestos.
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** CONFERENCES News **
Pharmacognosy, Phytochemistry & Natural Products conference, October 21-23, 2013, Hyderabad, India
http://mnt.to/a/4h2h
A paradigm of new drug development from herbal resources, at Pharmacognosy, Phytochemistry & Natural Products conference during October 21-23, 2013 at Radisson Blu Plaza Hotel, Hyderabad, India.
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** COPD News **
Approval of once-daily dual bronchodilator Ultibro® Inhalation Capsules in Japan (QVA149) for the treatment of COPD
http://mnt.to/a/4gYY
Vectura Group plc (LSE: VEC) ("Vectura"), confirms that the Japanese Ministry of Health, Labour and Welfare (MHLW) approved Novartis' once-daily Ultibro® Inhalation Capsules (glycopyrronium 50 mcg / indacaterol 110 mcg), delivered through the Breezhaler® device, for relief of various symptoms due to airway obstruction in chronic obstructive pulmonary disease (COPD).
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** DEPRESSION News **
New research into mental wellbeing and HIV highlights need for greater support
http://mnt.to/a/4gZb
New research by leading HIV support agency Positively UK, in partnership with Janssen, has provided fresh insights into the links between HIV and poor mental wellbeing. The results, launched at Positively UK's Conference of People Living With HIV and published in the States of Mind Report, highlight the burden of poor mental health in the HIV community.
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** DIABETES News **
Metabolism influenced by lifestyle via DNA methylation
http://mnt.to/a/4gYs
An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum Munchen have now identified 28 DNA alterations associated with metabolic traits.
Improved outcomes for patients with type 1 diabetes offered by new islet cell transplant procedure
http://mnt.to/a/4gY7
The latest approach to islet transplantation, in which clusters of insulin-producing cells known as islets are transplanted from a donor pancreas into another person's liver, has produced substantially improved results for patients with type 1 diabetes, and may offer a more durable alternative to a whole pancreas transplant.
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** EATING DISORDERS News **
Binge-eating disorder linked to lifelong impairments in 12-country study
http://mnt.to/a/4gZr
Binge-eating disorder, designated only months ago by the American Psychiatric Association as a diagnosis in its Diagnostic and Statistical Manual of Mental Disorders, is associated with substantial lifelong impairments comparable to those of bulimia nervosa, according to a World Health Organization study based on community epidemiological surveys conducted in 12 nations worldwide.
Clinical research study first to compare refeeding protocols for anorexia nervosa
http://mnt.to/a/4gYd
Higher calorie diets produce twice the rate of weight gain compared to the lower calorie diets that currently are recommended for adolescents hospitalized with anorexia nervosa, according to a study by researchers at UCSF Benioff Children's Hospital.
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** EPILEPSY News **
How brain cell connections get cemented early in life could aid understanding of autism, schizophrenia, intellectual disability
http://mnt.to/a/4gYD
When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses.But as we grow and learn, things get a bit more stable.
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** EYE HEALTH / BLINDNESS News **
Early test warns of world's leading eye disease, age-related macular degeneration (AMD)
http://mnt.to/a/4gZg
A new, quick and simple eye test can predict who is more at risk of age-related macular degeneration (AMD), a leading cause of blindness worldwide.Researchers at Australia's Vision Centre (VC) have found that while people with early AMD can still see in fine detail, other parts of their vision may be damaged and this isn't revealed by current eye tests.
Statin use may raise cataract risk
http://mnt.to/a/4gYG
New research suggests that use of statins, a class of drugs taken by millions of Americans with high cholesterol, is linked to a higher risk for developing cataracts.Dr. Jessica Leuschen, of the San Antonio Military Medical Center, Texas, and colleagues report their findings in a paper published online in JAMA Ophthalmology.
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** FERTILITY News **
Solution to puzzle of brain circuitry controlling fertility
http://mnt.to/a/4gYt
In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago.
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** FLU / COLD / SARS News **
H1N1 flu: pregnant women can safely take vaccine
http://mnt.to/a/4h24
The question of whether or not to vaccinate against the flu is just one of many decisions pregnant women must make. However, a new large national study may put some fears to rest after revealing evidence that the H1N1 vaccine is safe during pregnancy.
Pandemic 'natural experiment' brings scientists closer to universal flu vaccine
http://mnt.to/a/4gYN
Scientists have moved closer to developing a universal flu vaccine after using the 2009 pandemic as a natural experiment to study why some people seem to resist severe illness.Researchers at Imperial College London asked volunteers to donate blood samples just as the swine flu pandemic was getting underway and report any symptoms they experienced over the next two flu seasons.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Eradicating Helicobacter pylori
http://mnt.to/a/4gYr
Gut-dwelling bacteria are attracting increasing attention, particularly those associated with human diseases. Helicobacter pylori is found in the stomach of humans, where it may cause chronic gastritis and gastric ulcers, although the majority of infections are asymptomatic.
----------------------------------------------
** GENETICS News **
New method for analyzing gene expression in single cells opens window into tumors and other tissues
http://mnt.to/a/4gYS
A team of researchers affiliated with Ludwig Cancer Research and the Karolinska Institutet in Sweden report in the current issue of Nature Methods a dramatically improved technique for analyzing the genes expressed within a single cell -- a capability of relevance to everything from basic research to future cancer diagnostics.
Metabolism influenced by lifestyle via DNA methylation
http://mnt.to/a/4gYs
An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum Munchen have now identified 28 DNA alterations associated with metabolic traits.
----------------------------------------------
** HEART DISEASE News **
In pulmonary arterial hypertension, prostacyclin analogs and PDE 5 inhibitors synergistically stimulate ATP release from human RBCs
http://mnt.to/a/4gYy
Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin (PGI2) analogs and phosphodiesterase 5 (PDE5) inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension (PAH).
Lives of patients with acute heart attack saved by blood pressure cuff
http://mnt.to/a/4gYm
In patients with an acute heart attack, remote ischemic conditioning - intermittent inflation of a blood pressure cuff to cut off blood flow to the arm during transportation to hospital for acute balloon dilatation - reduces subsequent cardiac symptoms and mortality after acute heart attack.
Heart disease patients benefit from high intensity training
http://mnt.to/a/4gYk
High-intensity exercise is shown to be protective against coronary heart disease (CHD) and is well known as a popular and time-saving approach to getting fit. But what about people who already have heart disease? Previously, these patients were told to exercise, but only at a moderate intensity to protect their hearts.
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** HIV / AIDS News **
UNAIDS reports a 52% reduction in new HIV infections among children and a combined 33% reduction among adults and children since 2001
http://mnt.to/a/4gZh
As world leaders prepare to meet at the United Nations General Assembly to review progress towards the Millennium Development Goals - a new report from the Joint United Nations Programme on HIV/AIDS (UNAIDS) shows dramatic acceleration towards reaching 2015 global targets on HIV.
New research into mental wellbeing and HIV highlights need for greater support
http://mnt.to/a/4gZb
New research by leading HIV support agency Positively UK, in partnership with Janssen, has provided fresh insights into the links between HIV and poor mental wellbeing. The results, launched at Positively UK's Conference of People Living With HIV and published in the States of Mind Report, highlight the burden of poor mental health in the HIV community.
Exploring barriers to HIV vaccine response
http://mnt.to/a/4gYF
Researchers at The Scripps Research Institute (TSRI) discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.
In HIV, elvitegravir fixed combination has lesser benefit for treatment-naive patients
http://mnt.to/a/4gYn
More AIDS-defining illnesses and severe side effects than with appropriate comparator therapyThe drug combination of elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil (elvitegravir fixed combination, trade name: Stribild) has been approved in Germany since May 2013 for the treatment of adults infected with human immunodeficiency virus type 1 (HIV-1).
News from the Journal of AIDS, Oct. issue
http://mnt.to/a/4gY5
Early changes of AIDS-related lymphoma; new approaches to promote circumcision to reduce HIV risk; updates on HIV lifetime costs of care and quality of life estimatesJAIDS: Journal of Acquired Immune Deficiency Syndromes announced its research article highlights from the October issue now available on the journal website.
DAVEI 'tricks' HIV virus into 'thinking' it is about to infect a healthy cell, when, in fact, there is nothing there for it to infect
http://mnt.to/a/4gY2
Pinning down an effective way to combat the spread of the human immunodeficiency virus, the viral precursor to AIDS, has long been a challenge for scientists and physicians, because the virus is an elusive one that mutates frequently and, as a result, quickly becomes immune to medication.
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** HYPERTENSION News **
In pulmonary arterial hypertension, prostacyclin analogs and PDE 5 inhibitors synergistically stimulate ATP release from human RBCs
http://mnt.to/a/4gYy
Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin (PGI2) analogs and phosphodiesterase 5 (PDE5) inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension (PAH).
----------------------------------------------
** IMMUNE SYSTEM / VACCINES News **
Pandemic 'natural experiment' brings scientists closer to universal flu vaccine
http://mnt.to/a/4gYN
Scientists have moved closer to developing a universal flu vaccine after using the 2009 pandemic as a natural experiment to study why some people seem to resist severe illness.Researchers at Imperial College London asked volunteers to donate blood samples just as the swine flu pandemic was getting underway and report any symptoms they experienced over the next two flu seasons.
Exploring barriers to HIV vaccine response
http://mnt.to/a/4gYF
Researchers at The Scripps Research Institute (TSRI) discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient.
----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Eradicating Helicobacter pylori
http://mnt.to/a/4gYr
Gut-dwelling bacteria are attracting increasing attention, particularly those associated with human diseases. Helicobacter pylori is found in the stomach of humans, where it may cause chronic gastritis and gastric ulcers, although the majority of infections are asymptomatic.
----------------------------------------------
** LIVER DISEASE / HEPATITIS News **
New non-invasive alternative to needle biopsy for pediatric liver disease
http://mnt.to/a/4gYv
A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.
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** LYMPHOMA / LEUKEMIA / MYELOMA News **
News from the Journal of AIDS, Oct. issue
http://mnt.to/a/4gY5
Early changes of AIDS-related lymphoma; new approaches to promote circumcision to reduce HIV risk; updates on HIV lifetime costs of care and quality of life estimatesJAIDS: Journal of Acquired Immune Deficiency Syndromes announced its research article highlights from the October issue now available on the journal website.
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** MEDICAL DEVICES / DIAGNOSTICS News **
Mobile medical apps: FDA issues final guidance
http://mnt.to/a/4gZn
The US Food and Drug Administration (FDA) announced that it has issued final guidance for developers of medical mobile apps - user-friendly software programs that run on mobile communication devices, such as smartphones and tablet computers.
Early test warns of world's leading eye disease, age-related macular degeneration (AMD)
http://mnt.to/a/4gZg
A new, quick and simple eye test can predict who is more at risk of age-related macular degeneration (AMD), a leading cause of blindness worldwide.Researchers at Australia's Vision Centre (VC) have found that while people with early AMD can still see in fine detail, other parts of their vision may be damaged and this isn't revealed by current eye tests.
Accurately identifying neck tumors using robotics improves treatment, survival, Pitt study finds
http://mnt.to/a/4gZf
Using robotic surgery done through the mouth to more accurately identify the cause of lumps in the neck can help physicians to better target more personalized therapies for patients and dramatically improve survival, according to a study led by the University of Pittsburgh's Umamaheswar Duvvuri, M.
Artificial kidney could help those with renal failure
http://mnt.to/a/4gZc
It may not look like one, but the Implantable Artificial Kidney device has been designed to function in the same way as a human kidney. By extracting waste and keeping nutrients needed by the body, it could one day help those with chronic renal failure.
A clear look at a crucial step in cancer metastasis
http://mnt.to/a/4gYC
Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor.
New non-invasive alternative to needle biopsy for pediatric liver disease
http://mnt.to/a/4gYv
A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.
Nobel prize-winning sodium-potassium pump: Crucial new insight into its secrets
http://mnt.to/a/4gYp
Jens Chr. Skou was awarded the Nobel Prize for his discovery of the sodium-potassium pump. Now, a team of researchers from Aarhus has completed the description of its structure. A result which is of vital importance for our understanding of the body's functions and essential for our understanding of illness and for the development of new medicines.
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** MEN'S HEALTH News **
Possible epigenetic sources of chronic aggressive behavior in boys
http://mnt.to/a/4gYK
Chronic aggressive behaviour exhibited by some boys from disadvantaged families may be due to epigenetic changes during pregnancy and early childhood. This is highlighted by two studies conducted by a team led by Richard E.
----------------------------------------------
** MENTAL HEALTH News **
New research into mental wellbeing and HIV highlights need for greater support
http://mnt.to/a/4gZb
New research by leading HIV support agency Positively UK, in partnership with Janssen, has provided fresh insights into the links between HIV and poor mental wellbeing. The results, launched at Positively UK's Conference of People Living With HIV and published in the States of Mind Report, highlight the burden of poor mental health in the HIV community.
Mental health 'eye test' breakthrough up for national award
http://mnt.to/a/4gZ4
An eye movement test to assist diagnosis of major adult psychiatric disorders has made the final stage of a prestigious national contest recognising Scotland's entrepreneurial innovations. Devised by researchers from the University of Aberdeen, the test recognises unusual eye movements to help clinicians identify illnesses such as schizophrenia, bipolar disorder and severe depression.
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** NEUROLOGY / NEUROSCIENCE News **
New anesthetics likely following propofol discovery
http://mnt.to/a/4gYL
Researchers at Washington University School of Medicine in St. Louis and Imperial College London have identified the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery.
Switch identified that controls growth of most aggressive brain tumor cells
http://mnt.to/a/4gYz
Researchers at UT Southwestern Medical Center have identified a cellular switch that potentially can be turned off and on to slow down, and eventually inhibit the growth of the most commonly diagnosed and aggressive malignant brain tumor.
Neurofeedback can enhance the signal-to-noise ratio in thought, enabling a sharper focus on tasks
http://mnt.to/a/4gYx
The sweep of a needle across the grooves of a worn vinyl record carries distinct sounds: hisses, scratches, even the echo of skips. For many years, though, those yearning to hear Frank Sinatra sing "Fly Me to the Moon" have been able to listen to his light baritone with technical clarity, courtesy of the increased signal-to-noise ratio of digital remasterings.
Solution to puzzle of brain circuitry controlling fertility
http://mnt.to/a/4gYt
In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago.
Dog food preservative may thwart pain and damage of peripheral neuropathy
http://mnt.to/a/4gXZ
Working with cells in test tubes and in mice, researchers at Johns Hopkins have discovered that a chemical commonly used as a dog food preservative may prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.
----------------------------------------------
** NUTRITION / DIET News **
Dopamine cells critical in sugar/sweetener choice, leading to a higher likelihood of sugar consumption later
http://mnt.to/a/4gYP
The results of the new study imply that it is hard to fool the brain by providing it with 'energyless' sweet flavours. Our pleasure in consuming sweet solutions is driven to a great extent by the amount of energy it provides: greater reward in the brain is attributed to sugars compared to artificial sweeteners.
Metabolism influenced by lifestyle via DNA methylation
http://mnt.to/a/4gYs
An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum Munchen have now identified 28 DNA alterations associated with metabolic traits.
Clinical research study first to compare refeeding protocols for anorexia nervosa
http://mnt.to/a/4gYd
Higher calorie diets produce twice the rate of weight gain compared to the lower calorie diets that currently are recommended for adolescents hospitalized with anorexia nervosa, according to a study by researchers at UCSF Benioff Children's Hospital.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
Norgine and Takeda announce the new drug application approval of Oblean (cetilistat) tablets 120mg in Japan
http://mnt.to/a/4gYX
Norgine and Takeda Pharmaceutical Company Limited has announced that the Japanese Ministry of Health, Labour and Welfare has approved the New Drug Application (NDA) of OBLEAN Tablets 120mg for the treatment of obesity with complications.
Dopamine cells critical in sugar/sweetener choice, leading to a higher likelihood of sugar consumption later
http://mnt.to/a/4gYP
The results of the new study imply that it is hard to fool the brain by providing it with 'energyless' sweet flavours. Our pleasure in consuming sweet solutions is driven to a great extent by the amount of energy it provides: greater reward in the brain is attributed to sugars compared to artificial sweeteners.
A new way to prevent overweight and obesity - primary weight maintenance
http://mnt.to/a/4gYq
The same message to everyone does not work if the goal is to prevent overweight and obesity in the population. It is also important to reach groups normally considered as being at low risk for gaining weight.
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** PAIN / ANESTHETICS News **
New anesthetics likely following propofol discovery
http://mnt.to/a/4gYL
Researchers at Washington University School of Medicine in St. Louis and Imperial College London have identified the site where the widely used anesthetic drug propofol binds to receptors in the brain to sedate patients during surgery.
How the body responds to pain: Groundbreaking research
http://mnt.to/a/4gYb
The bodies of mammals, including humans, respond to injury by releasing endogenous opioids - compounds that mitigate acute pain. A team of researchers led by those at the University of Kentucky has uncovered groundbreaking new information about how the body responds to traumatic injury with the development of a surprisingly long-lasting opioid mechanism of natural chronic pain control.
Dog food preservative may thwart pain and damage of peripheral neuropathy
http://mnt.to/a/4gXZ
Working with cells in test tubes and in mice, researchers at Johns Hopkins have discovered that a chemical commonly used as a dog food preservative may prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.
----------------------------------------------
** PEDIATRICS / CHILDREN'S HEALTH News **
Midday naps boost learning in preschoolers
http://mnt.to/a/4gZq
A new study finds that midday naps boost learning in preschoolers, suggesting if policymakers eliminate classroom naps for young children to allow more time for educational activity, it could backfire.
Mothers who bedshare with infants breastfeed longer
http://mnt.to/a/4gZ3
A new study suggests that mothers who frequently bedshare with their infants are more likely to breastfeed for longer, even though bedsharing has been previously linked to heightened risk of sudden infant death syndrome (SIDS).
Possible epigenetic sources of chronic aggressive behavior in boys
http://mnt.to/a/4gYK
Chronic aggressive behaviour exhibited by some boys from disadvantaged families may be due to epigenetic changes during pregnancy and early childhood. This is highlighted by two studies conducted by a team led by Richard E.
New non-invasive alternative to needle biopsy for pediatric liver disease
http://mnt.to/a/4gYv
A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.
Psychopathic traits in development during the teenage years, not cast in stone
http://mnt.to/a/4gY3
Most youths are concerned about other people's feelings, they feel bad or guilty when they have done something wrong and they adhere to social rules. A small group of youths, however, does not.
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** PREGNANCY / OBSTETRICS News **
H1N1 flu: pregnant women can safely take vaccine
http://mnt.to/a/4h24
The question of whether or not to vaccinate against the flu is just one of many decisions pregnant women must make. However, a new large national study may put some fears to rest after revealing evidence that the H1N1 vaccine is safe during pregnancy.
Mothers who bedshare with infants breastfeed longer
http://mnt.to/a/4gZ3
A new study suggests that mothers who frequently bedshare with their infants are more likely to breastfeed for longer, even though bedsharing has been previously linked to heightened risk of sudden infant death syndrome (SIDS).
Clinical trial strives to provide optimal care during high-risk pregnancies with smaller than normal babies
http://mnt.to/a/4gYV
Researchers are conducting a clinical trial to help determine the best timing of delivery in preterm pregnancies complicated by poor fetal growth. Preliminary results from the trial, which are published early online in Ultrasound in Obstetrics & Gynecology, demonstrate better than expected health outcomes in this high-risk group of fetuses.
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** PRIMARY CARE / GENERAL PRACTICE News **
Study findings may affect how clinicians and health systems deliver patient-centered care
http://mnt.to/a/4gYB
Psychiatrists and psychologists have long understood that an individual's personality can define how he or she views the world around them, reacts to situations, and interacts with others. It now appears that personality traits can be linked to the frequency with which older adults use expensive health care services.
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** PSYCHOLOGY / PSYCHIATRY News **
Married cancer patients 'likely to live longer'
http://mnt.to/a/4gZP
People who are married when they are diagnosed with cancer are more likely to live longer, compared with those who are unmarried. This is according to a new study published in the Journal of Clinical Oncology.
Binge-eating disorder linked to lifelong impairments in 12-country study
http://mnt.to/a/4gZr
Binge-eating disorder, designated only months ago by the American Psychiatric Association as a diagnosis in its Diagnostic and Statistical Manual of Mental Disorders, is associated with substantial lifelong impairments comparable to those of bulimia nervosa, according to a World Health Organization study based on community epidemiological surveys conducted in 12 nations worldwide.
Midday naps boost learning in preschoolers
http://mnt.to/a/4gZq
A new study finds that midday naps boost learning in preschoolers, suggesting if policymakers eliminate classroom naps for young children to allow more time for educational activity, it could backfire.
Alcohol-related violence dependent on drinking 'context'
http://mnt.to/a/4gZ7
Although a high volume and frequency of drinking has been linked to an increase in violence toward a loved one, new research suggests that the context in which drinking occurs can play a role in violence against partners.
Fighting fears possible during sleep, study shows
http://mnt.to/a/4gZ2
For many patients with phobias, typical treatment involves gradual exposure to the feared object or situation. But researchers have now found that emotional memory can be manipulated during sleep, paving the way to new phobia treatments as we dream.
New insight into body representation brain disorders provided by sensory illusion
http://mnt.to/a/4gYT
People can be easily tricked into believing an artificial finger is their own, shows a study published in The Journal of Physiology. The results reveal that the brain does not require multiple signals to build a picture body ownership, as this is the first time the illusion has been created using sensory inputs from the muscle alone.
'Odour is a means of chemical communication between mother and child' - Johannes Frasnelli, University of Montreal
http://mnt.to/a/4gYM
What woman has not wanted to gobble up a baby placed in her arms, even if the baby is not hers? This reaction, which everyone has noticed or felt, could have biological underpinnings related to maternal functions.
Possible epigenetic sources of chronic aggressive behavior in boys
http://mnt.to/a/4gYK
Chronic aggressive behaviour exhibited by some boys from disadvantaged families may be due to epigenetic changes during pregnancy and early childhood. This is highlighted by two studies conducted by a team led by Richard E.
Neurofeedback can enhance the signal-to-noise ratio in thought, enabling a sharper focus on tasks
http://mnt.to/a/4gYx
The sweep of a needle across the grooves of a worn vinyl record carries distinct sounds: hisses, scratches, even the echo of skips. For many years, though, those yearning to hear Frank Sinatra sing "Fly Me to the Moon" have been able to listen to his light baritone with technical clarity, courtesy of the increased signal-to-noise ratio of digital remasterings.
Psychopathic traits in development during the teenage years, not cast in stone
http://mnt.to/a/4gY3
Most youths are concerned about other people's feelings, they feel bad or guilty when they have done something wrong and they adhere to social rules. A small group of youths, however, does not.
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** PUBLIC HEALTH News **
What is heat stroke or sunstroke?
http://mnt.to/a/4h2Q
Heat stroke, also known as sunstroke, is a serious medical condition, a medical emergency, when the body's temperature rises too high as a result of excessive heat exposure. The body loses its ability to cool itself and overheats.
English hospital trusts fall short of recommended standards on post mortem consent
http://mnt.to/a/4gXB
Many hospital trusts in England and Wales are falling short of the recommended standards on obtaining consent for a post mortem, indicates a snapshot survey of practice published online in the Journal of Clinical Pathology.
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** REGULATORY AFFAIRS / DRUG APPROVALS News **
Mobile medical apps: FDA issues final guidance
http://mnt.to/a/4gZn
The US Food and Drug Administration (FDA) announced that it has issued final guidance for developers of medical mobile apps - user-friendly software programs that run on mobile communication devices, such as smartphones and tablet computers.
RELVAR™ ELLIPTA™ receives regulatory approval in Japan
http://mnt.to/a/4gYZ
Skyepharma PLC (LSE: SKP), the expert oral and inhalation drug delivery company, announces that the regulatory committee (Bunka-Kai) of the Japanese Ministry of Health, Labour and Welfare ("MHLW") has approved RELVARTM ELLIPTATM (FF/VI) for the treatment of bronchial asthma (in cases where concurrent use of inhaled corticosteroid and long- acting inhaled beta2 agonist is required).
Approval of once-daily dual bronchodilator Ultibro® Inhalation Capsules in Japan (QVA149) for the treatment of COPD
http://mnt.to/a/4gYY
Vectura Group plc (LSE: VEC) ("Vectura"), confirms that the Japanese Ministry of Health, Labour and Welfare (MHLW) approved Novartis' once-daily Ultibro® Inhalation Capsules (glycopyrronium 50 mcg / indacaterol 110 mcg), delivered through the Breezhaler® device, for relief of various symptoms due to airway obstruction in chronic obstructive pulmonary disease (COPD).
Norgine and Takeda announce the new drug application approval of Oblean (cetilistat) tablets 120mg in Japan
http://mnt.to/a/4gYX
Norgine and Takeda Pharmaceutical Company Limited has announced that the Japanese Ministry of Health, Labour and Welfare has approved the New Drug Application (NDA) of OBLEAN Tablets 120mg for the treatment of obesity with complications.
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** RESPIRATORY / ASTHMA News **
RELVAR™ ELLIPTA™ receives regulatory approval in Japan
http://mnt.to/a/4gYZ
Skyepharma PLC (LSE: SKP), the expert oral and inhalation drug delivery company, announces that the regulatory committee (Bunka-Kai) of the Japanese Ministry of Health, Labour and Welfare ("MHLW") has approved RELVARTM ELLIPTATM (FF/VI) for the treatment of bronchial asthma (in cases where concurrent use of inhaled corticosteroid and long- acting inhaled beta2 agonist is required).
In pulmonary arterial hypertension, prostacyclin analogs and PDE 5 inhibitors synergistically stimulate ATP release from human RBCs
http://mnt.to/a/4gYy
Researchers at Saint Louis University School of Medicine have discovered a novel interaction between prostacyclin (PGI2) analogs and phosphodiesterase 5 (PDE5) inhibitors, two groups of drugs used in the treatment of pulmonary arterial hypertension (PAH).
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** SCHIZOPHRENIA News **
How brain cell connections get cemented early in life could aid understanding of autism, schizophrenia, intellectual disability
http://mnt.to/a/4gYD
When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses.But as we grow and learn, things get a bit more stable.
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** SENIORS / AGING News **
Study findings may affect how clinicians and health systems deliver patient-centered care
http://mnt.to/a/4gYB
Psychiatrists and psychologists have long understood that an individual's personality can define how he or she views the world around them, reacts to situations, and interacts with others. It now appears that personality traits can be linked to the frequency with which older adults use expensive health care services.
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** SEXUAL HEALTH / STDS News **
News from the Journal of AIDS, Oct. issue
http://mnt.to/a/4gY5
Early changes of AIDS-related lymphoma; new approaches to promote circumcision to reduce HIV risk; updates on HIV lifetime costs of care and quality of life estimatesJAIDS: Journal of Acquired Immune Deficiency Syndromes announced its research article highlights from the October issue now available on the journal website.
Develop after-sex contraceptive pill for routine use, urge researchers - political opposition biggest hurdle
http://mnt.to/a/4gXC
A contraceptive pill that could be routinely used after, rather than before, sex and fertilisation is probably scientifically feasible and would probably be welcomed by many women, say researchers in the Journal of Family Planning and Reproductive Health Care.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Midday naps boost learning in preschoolers
http://mnt.to/a/4gZq
A new study finds that midday naps boost learning in preschoolers, suggesting if policymakers eliminate classroom naps for young children to allow more time for educational activity, it could backfire.
Fighting fears possible during sleep, study shows
http://mnt.to/a/4gZ2
For many patients with phobias, typical treatment involves gradual exposure to the feared object or situation. But researchers have now found that emotional memory can be manipulated during sleep, paving the way to new phobia treatments as we dream.
American College of Physicians releases new recommendations for treating obstructive sleep apnea
http://mnt.to/a/4gY4
People diagnosed with obstructive sleep apnea (OSA) should lose weight and use continuous positive airway pressure (CPAP) as initial therapy, according to new recommendations from the American College of Physicians (ACP) published today in Annals of Internal Medicine, ACP's flagship journal.
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** SPORTS MEDICINE / FITNESS News **
Heart disease patients benefit from high intensity training
http://mnt.to/a/4gYk
High-intensity exercise is shown to be protective against coronary heart disease (CHD) and is well known as a popular and time-saving approach to getting fit. But what about people who already have heart disease? Previously, these patients were told to exercise, but only at a moderate intensity to protect their hearts.
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** STATINS News **
Statin use may raise cataract risk
http://mnt.to/a/4gYG
New research suggests that use of statins, a class of drugs taken by millions of Americans with high cholesterol, is linked to a higher risk for developing cataracts.Dr. Jessica Leuschen, of the San Antonio Military Medical Center, Texas, and colleagues report their findings in a paper published online in JAMA Ophthalmology.
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** TRANSPLANTS / ORGAN DONATIONS News **
Improved outcomes for patients with type 1 diabetes offered by new islet cell transplant procedure
http://mnt.to/a/4gY7
The latest approach to islet transplantation, in which clusters of insulin-producing cells known as islets are transplanted from a donor pancreas into another person's liver, has produced substantially improved results for patients with type 1 diabetes, and may offer a more durable alternative to a whole pancreas transplant.
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** UROLOGY / NEPHROLOGY News **
Artificial kidney could help those with renal failure
http://mnt.to/a/4gZc
It may not look like one, but the Implantable Artificial Kidney device has been designed to function in the same way as a human kidney. By extracting waste and keeping nutrients needed by the body, it could one day help those with chronic renal failure.
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** VETERINARY News **
Ohio state vet discusses investigation into mystery dog illness
http://mnt.to/a/4gZ6
Several dogs in Ohio have recently presented with vomiting and bloody diarrhea, and four of them have died. The symptoms aren't uncommon, but the cause might be. Veterinarians across the country are currently investigating these cases to see what sickened or killed the dogs in Ohio, including a possible link to a newly emerging canine circovirus.
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** WOMEN'S HEALTH / GYNECOLOGY News **
Mothers who bedshare with infants breastfeed longer
http://mnt.to/a/4gZ3
A new study suggests that mothers who frequently bedshare with their infants are more likely to breastfeed for longer, even though bedsharing has been previously linked to heightened risk of sudden infant death syndrome (SIDS).
Clinical trial strives to provide optimal care during high-risk pregnancies with smaller than normal babies
http://mnt.to/a/4gYV
Researchers are conducting a clinical trial to help determine the best timing of delivery in preterm pregnancies complicated by poor fetal growth. Preliminary results from the trial, which are published early online in Ultrasound in Obstetrics & Gynecology, demonstrate better than expected health outcomes in this high-risk group of fetuses.
Develop after-sex contraceptive pill for routine use, urge researchers - political opposition biggest hurdle
http://mnt.to/a/4gXC
A contraceptive pill that could be routinely used after, rather than before, sex and fertilisation is probably scientifically feasible and would probably be welcomed by many women, say researchers in the Journal of Family Planning and Reproductive Health Care.
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