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 Pediatric anesthetics research at NCTR is aimed at closing the research gaps related to the effects of anesthesia on the developing brain, with the hope that research findings may lead to new and safer strategies for the use of anesthetics in the pediatric population. Current research is utilizing state-of-the-art imaging techniques-coupling a Computed Tomography(CT) instrument to a Micro-Positron Emission Tomography (microPET) imaging device-to provide a powerful, non-invasive tool for detecting and monitoring adverse effects on brain tissue that are associated with pediatric anesthesia. This collaborative project with the Center for Drug Evaluation and Research (CDER) is focused on evaluating the neurotoxicity associated with pediatric exposures to two general anesthetics, sevoflurane or propofol, and will provide critical information concerning the risks associated with these agents and provide data that can contribute to the FDA's regulatory needs. To track the progress of this research, visit the FDA-TRACK NCTR Pediatric Anesthesia Research Project. |
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