Medical News Today daily newsletter - 11 April 2014

Dear kostik,

Welcome to today's Medical News Today newsletter, containing the most recent headlines from your chosen news categories.

----------------------------------------------
** ADHD News **

How do our brains differentiate information about places and faces?
http://mnt.to/l/4mJY
Neuroscientists investigate 'object-based attention,' which allows us to pick a face we recognize out of a crowd, and find it is produced by three synchronized brain regions.

----------------------------------------------
** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **

Female drinkers face greater risks to their health from alcohol consumption
http://mnt.to/l/4mGW
The increased risk of death associated with alcohol intake is not the same for men and women. A study that compared the amount of alcohol consumed and death from all causes among nearly 2.

HIV/STI prevention: the double whammy of multiple sex partners and drinking
http://mnt.to/l/4mGk
The cartoon character Homer J. Simpson once said "Alcohol: The source of, and solution to, all of life's problems.

----------------------------------------------
** ALZHEIMER'S / DEMENTIA News **

Improving cognition later in life through physical activity
http://mnt.to/l/4mGZ
Physical activity in midlife seems to protect from dementia in old age, according to a study carried out at the University of Eastern Finland.

Innovative, coordinated brain care could save billions of health care dollars
http://mnt.to/l/4mGb
Studies have shown that a new patient and caregiver centered model of innovative, coordinated brain care for older adults improves health outcomes and quality of care for those with cognitive...

----------------------------------------------
** ANXIETY / STRESS News **

Breastfeeding while on antidepressants: 'benefits outweigh risks'
http://mnt.to/l/4mJS
Though women who breastfeed are typically warned that medications can enter breast milk, new research suggests the benefits of remaining on antidepressants outweigh the risks.

Psychological distress frequently experienced by civilians working with military in war zones
http://mnt.to/l/4mGX
The punishing psychological toll endured by military personnel in war zones has been extensively documented for years by researchers, perhaps more than ever in the wake of recent military...

Rapid antidepressant effect in depression achieved with intranasal ketamine
http://mnt.to/l/4mGn
A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant...

Research linked to stress in mice confirms blood-brain comparison is valid
http://mnt.to/l/4mGm
Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone - and showing signs of anxiety - are...

----------------------------------------------
** ARTHRITIS / RHEUMATOLOGY News **

Prolotherapy: nonsurgical treatment for knee osteoarthritis
http://mnt.to/l/4mGd
A new nonsurgical approach to treating chronic pain and stiffness associated with knee osteoarthritis has demonstrated significant, lasting improvement in knee pain, function, and stiffness.

----------------------------------------------
** AUTISM News **

During prenatal brain development lipid levels impact autism
http://mnt.to/l/4mGj
In a groundbreaking York University study, researchers have found that abnormal levels of lipid molecules in the brain can affect the interaction between two key neural pathways in early...

----------------------------------------------
** BIOLOGY / BIOCHEMISTRY News **

New target in flu virus may open route to better drugs
http://mnt.to/l/4mJd
The influenza A virus produces a protein that manages to outwit the body's natural defenses. Blocking it offers a route to new flu drugs, say the researchers who discovered it.

How does the 'kissing disease' replicate itself?
http://mnt.to/l/4mJ4
Researchers have discovered how Epstein-Barr virus takes over cells, allowing the virus to make a copy of itself - a finding that could produce drug targets.

Obsessive-compulsive disorder may reflect a propensity for bad habits
http://mnt.to/l/4mJ2
Two new studies published in Biological Psychiatry shed light on the propensity for habit formation in obsessive-compulsive disorder (OCD).

Researchers demonstrates advantages of the HOPE fixation strategy
http://mnt.to/l/4mG8
A new way of preparing patient tissue for analyses might soon become the new standard.

Team solves decades-old mystery of how cells keep from bursting
http://mnt.to/l/4mCD
A team led by scientists at The Scripps Research Institute (TSRI) has identified a long-sought protein that facilitates one of the most basic functions of cells: regulating their volume to...

----------------------------------------------
** BLOOD / HEMATOLOGY News **

Phase 3 results announced for paediatric study of investigational therapy Eloctate<sup>(TM)</sup> for haemophilia A
http://mnt.to/l/4mJ7
Biogen Idec and Swedish Orphan Biovitrum AB (Sobi) have released positive top-line results of the Kids A-LONG Phase 3 clinical study that evaluated the safety and efficacy of Eloctate(TM), an...

Newly invented hydrogel may help 'nuanced' healing of surgical wounds
http://mnt.to/l/4mHh
Synthetic collagen invented at Rice University may help wounds heal by directing the natural clotting of blood.

----------------------------------------------
** BONES / ORTHOPEDICS News **

Development of individual cranial bones influenced by brain size
http://mnt.to/l/4mHc
Embryonic development in animals - except mice and rats - remains largely unexplored.

Potential target identified to combat muscle wasting
http://mnt.to/l/4mH3
The pathological atrophy of skeletal muscle is a serious biomedical problem for which no effective treatment is currently available.

Prolotherapy: nonsurgical treatment for knee osteoarthritis
http://mnt.to/l/4mGd
A new nonsurgical approach to treating chronic pain and stiffness associated with knee osteoarthritis has demonstrated significant, lasting improvement in knee pain, function, and stiffness.

----------------------------------------------
** BREAST CANCER News **

A high-fat diet can increase risk of certain types of breast cancer
http://mnt.to/l/4mGS
High total and saturated fat intake were associated with greater risk of estrogen receptor- and progesterone receptor-positive (ER+PR+) breast cancer (BC), and human epidermal growth factor 2...

Tumor growth can be spurred by breast cancer cell subpopulation cooperation
http://mnt.to/l/4mGc
Subpopulations of breast cancer cells sometimes cooperate to aid tumor growth, according to Penn State College of Medicine researchers, who believe that understanding the relationship between...

Study unlocks secrets of breast tissue
http://mnt.to/l/4mG9
A unique population of microbes in the female breast may lay the groundwork for understanding how this bacterial community contributes to health and disease, according to a new study out of...

----------------------------------------------
** CANCER / ONCOLOGY News **

Copper starvation could be promising treatment for some cancers
http://mnt.to/l/4mJc
Researchers who found some cancers caused by a mutation in the BRAF gene need copper to fuel tumor growth, suggest they may be treatable with drugs that block copper absorption.

Targeting cancer's thirst for copper
http://mnt.to/l/4mGN
Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report.

Cancer drug targets opened by kinesin-5 structure
http://mnt.to/l/4mGg
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a...

----------------------------------------------
** CARDIOVASCULAR / CARDIOLOGY News **

A U.S. first - new technology allows full-body MRI for pacemaker patient
http://mnt.to/l/4mHN
Providence Saint Joseph Medical Center is the first hospital in the nation to conduct an MRI scan of a patient implanted with a new MRI-compatible pacemaker - a breakthrough because metal...

30-day survival measurement may be related to spike in postoperative cardiac surgery deaths
http://mnt.to/l/4mHg
Analyzing a national database of hospital inpatient records, a team of researchers reports an expected spike in mortality six days after cardiac surgery, but also a more surprising and...

Risks from refrigerant in cars may outweigh the benefits
http://mnt.to/l/4mGY
The refrigerant R1234yf is being considered for use in air conditioning systems in cars.

TOPCAT trial results show spironolactone did not reduce primary outcome, but did reduce hospitalizations for heart failure
http://mnt.to/l/4mGR
Findings from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, have revealed that adding the medication known as spironolactone...

----------------------------------------------
** CAREGIVERS / HOMECARE News **

Innovative, coordinated brain care could save billions of health care dollars
http://mnt.to/l/4mGb
Studies have shown that a new patient and caregiver centered model of innovative, coordinated brain care for older adults improves health outcomes and quality of care for those with cognitive...

----------------------------------------------
** CLINICAL TRIALS / DRUG TRIALS News **

Phase 3 results announced for paediatric study of investigational therapy Eloctate<sup>(TM)</sup> for haemophilia A
http://mnt.to/l/4mJ7
Biogen Idec and Swedish Orphan Biovitrum AB (Sobi) have released positive top-line results of the Kids A-LONG Phase 3 clinical study that evaluated the safety and efficacy of Eloctate(TM), an...

Gilead announces results from study of Sovaldi&reg; for retreatment of chronic hepatitis C in patients not cured with prior antiviral therapy
http://mnt.to/l/4mJ5
Gilead Sciences, Inc. has announced results from an open-label clinical trial (Study GS-US-334-0109) evaluating once-daily Sovaldi&reg; (sofosbuvir) 400 mg tablets for the retreatment of...

Moffitt Cancer Center begins Phase I clinical trial of new immunotherapy
http://mnt.to/l/4mHq
Moffitt Cancer Center has initiated a phase I clinical trial for a new immunotherapy drug, ID-G305, made by Immune Design.

----------------------------------------------
** COLORECTAL CANCER News **

Cancer drug targets opened by kinesin-5 structure
http://mnt.to/l/4mGg
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a...

----------------------------------------------
** COMPLEMENTARY MEDICINE / ALTERNATIVE MEDICINE News **

Oxidative damage to neurons alleviated by polysaccharides from Angelica sinensis
http://mnt.to/l/4mH9
According to traditional Chinese medicine, the roles of Angelica sinensis correlate with tonifying the blood and promoting its circulation.

----------------------------------------------
** CONFERENCES News **

14th Annual Strategic Project and Portfolio Management for Pharma, 26-28 January 2015, Spain
http://mnt.to/l/4mJX
14th
Annual Strategic Project and Portfolio Management for Pharma, 26-28 January 2015, SpainThe 14th Annual Conference on Strategic Project & Portfolio Management for Pharma will look at...

Translating Innovations in Diabetes Drug Development, 17-19 November 2014, London

http://mnt.to/l/4mJV
Translating Innovations in Diabetes Drug Development is being held on the 17-19 November 2014 in London, United KingdomThe global diabetes market is projected to double from $32bn to...

4th Edition Strategic Alliance Management for Pharma16-18 June 2014, Barcelona
http://mnt.to/l/4mJR
4th
Edition Strategic Alliance Management for Pharma is being held on the 16-18 June 2014 at the Avenida Palace Hotel Barcelona, SpainThe pharmaceutical industry is under immense...

5th Annual Protein Formulation Development and Drug Delivery Forum, 9-11 June 2014, Barcelona
http://mnt.to/l/4mJQ
5th
Annual Protein Formulation Development and Drug Delivery Forum is being held on 9-11 June 2014, at the Avenida Palace Hotel Barcelona, SpainOptimising protein formulation stages has...

----------------------------------------------
** DEPRESSION News **

Rapid antidepressant effect in depression achieved with intranasal ketamine
http://mnt.to/l/4mGn
A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant...

----------------------------------------------
** DERMATOLOGY News **

Newly invented hydrogel may help 'nuanced' healing of surgical wounds
http://mnt.to/l/4mHh
Synthetic collagen invented at Rice University may help wounds heal by directing the natural clotting of blood.

----------------------------------------------
** DIABETES News **

Translating Innovations in Diabetes Drug Development, 17-19 November 2014, London

http://mnt.to/l/4mJV
Translating Innovations in Diabetes Drug Development is being held on the 17-19 November 2014 in London, United KingdomThe global diabetes market is projected to double from $32bn to...

Proteomics International biomarker study moves closer to a CDx test for diabetic kidney disease
http://mnt.to/l/4mJ9
Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein...

Potential target identified to combat muscle wasting
http://mnt.to/l/4mH3
The pathological atrophy of skeletal muscle is a serious biomedical problem for which no effective treatment is currently available.

Consuming high-calorie foods may lead to brown fat cell 'whitening'
http://mnt.to/l/4mGV
Boston University researchers have learned new information about the consequences of overeating high-calorie foods.

Protein identified in fat and liver cells that can be altered to increase energy expenditure could lead to new obesity treatment
http://mnt.to/l/4mGQ
By manipulating a biochemical process that underlies cells' energy-burning abilities, investigators at Beth Israel Deaconess Medical Center (BIDMC) have made a novel discovery that could lead to...

----------------------------------------------
** EAR, NOSE AND THROAT News **

Lab-grown nostril and vagina constructed with similar techniques
http://mnt.to/l/4mHb
Scientists have engineered human cartilage for nostril reconstruction, while another team has grown artificial vaginas - both procedures used cells from the patients' own bodies.

----------------------------------------------
** ENDOCRINOLOGY News **

Study questions safety thresholds for hormone-disrupting chemicals
http://mnt.to/l/4mJT
Current human safety levels for exposure to endocrine-disrupting chemicals are based on studies of rodent models. But new research has now questioned the accuracy of this method.

----------------------------------------------
** FERTILITY News **

Are babies who wake to breastfeed at night trying to delay the birth of a sibling?
http://mnt.to/l/4mHd
In a new article published online in the journal Evolution, Medicine, and Public Health, Professor David Haig argues that infants that wake frequently at night to breastfeed are delaying the...

----------------------------------------------
** FLU / COLD / SARS News **

New target in flu virus may open route to better drugs
http://mnt.to/l/4mJd
The influenza A virus produces a protein that manages to outwit the body's natural defenses. Blocking it offers a route to new flu drugs, say the researchers who discovered it.

Researchers find that influenza has an Achilles' Heel
http://mnt.to/l/4mHQ
Flu epidemics cause up to half a million deaths worldwide each year, and emerging strains continually threaten to spread to humans and cause even deadlier pandemics.

----------------------------------------------
** GENETICS News **

How does the 'kissing disease' replicate itself?
http://mnt.to/l/4mJ4
Researchers have discovered how Epstein-Barr virus takes over cells, allowing the virus to make a copy of itself - a finding that could produce drug targets.

Targeting cancer's thirst for copper
http://mnt.to/l/4mGN
Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report.

New technique using DNA data could help doctors treat MRSA
http://mnt.to/l/4mGL
A team of scientists led by the University of Bath has developed a new technique to predict the toxicity of an MRSA infection from its DNA sequence.

International debate on genetically modified crops
http://mnt.to/l/4mGs
One of the world's most contentious food issues - Genetically Modified (GM) crops - was debated by some of the world's leading authorities on the subject at Queen's University Belfast.

Research linked to stress in mice confirms blood-brain comparison is valid
http://mnt.to/l/4mGm
Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone - and showing signs of anxiety - are...

Tumor growth can be spurred by breast cancer cell subpopulation cooperation
http://mnt.to/l/4mGc
Subpopulations of breast cancer cells sometimes cooperate to aid tumor growth, according to Penn State College of Medicine researchers, who believe that understanding the relationship between...

Research targets Parkinson's, Huntington's, other proteasomal diseases
http://mnt.to/l/4mG7
Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated in...

----------------------------------------------
** HEALTH INSURANCE / MEDICAL INSURANCE News **

Malpractice and other insurance costs could change with Affordable Care Act
http://mnt.to/l/4mGr
The expansion of health insurance accomplished under the Affordable Care Act may alter costs for several major types of liability insurance, although any such changes are likely to be modest...

----------------------------------------------
** HEART DISEASE News **

Consuming high-calorie foods may lead to brown fat cell 'whitening'
http://mnt.to/l/4mGV
Boston University researchers have learned new information about the consequences of overeating high-calorie foods.

TOPCAT trial results show spironolactone did not reduce primary outcome, but did reduce hospitalizations for heart failure
http://mnt.to/l/4mGR
Findings from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, have revealed that adding the medication known as spironolactone...

----------------------------------------------
** HIV / AIDS News **

HIV/STI prevention: the double whammy of multiple sex partners and drinking
http://mnt.to/l/4mGk
The cartoon character Homer J. Simpson once said "Alcohol: The source of, and solution to, all of life's problems.

----------------------------------------------
** HUNTINGTONS DISEASE News **

Research targets Parkinson's, Huntington's, other proteasomal diseases
http://mnt.to/l/4mG7
Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated in...

----------------------------------------------
** HYPERTENSION News **

A good patient-clinician relationship can improve health outcomes
http://mnt.to/l/4mGP
A meta-analysis of studies that investigated measures designed to improve health professionals' interactions with patients confirms that such efforts can produce health effects just as...

----------------------------------------------
** IMMUNE SYSTEM / VACCINES News **

Researchers find that influenza has an Achilles' Heel
http://mnt.to/l/4mHQ
Flu epidemics cause up to half a million deaths worldwide each year, and emerging strains continually threaten to spread to humans and cause even deadlier pandemics.

Moffitt Cancer Center begins Phase I clinical trial of new immunotherapy
http://mnt.to/l/4mHq
Moffitt Cancer Center has initiated a phase I clinical trial for a new immunotherapy drug, ID-G305, made by Immune Design.

----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **

New target in flu virus may open route to better drugs
http://mnt.to/l/4mJd
The influenza A virus produces a protein that manages to outwit the body's natural defenses. Blocking it offers a route to new flu drugs, say the researchers who discovered it.

How does the 'kissing disease' replicate itself?
http://mnt.to/l/4mJ4
Researchers have discovered how Epstein-Barr virus takes over cells, allowing the virus to make a copy of itself - a finding that could produce drug targets.

MRF Meningococcus Genome Library aids development of new typing test for meningococcal bacteria
http://mnt.to/l/4mH8
New research published in PLoS ONE has used data from the Meningitis Research Foundation (MRF) Meningococcus...

Study unlocks secrets of breast tissue
http://mnt.to/l/4mG9
A unique population of microbes in the female breast may lay the groundwork for understanding how this bacterial community contributes to health and disease, according to a new study out of...

Researchers demonstrates advantages of the HOPE fixation strategy
http://mnt.to/l/4mG8
A new way of preparing patient tissue for analyses might soon become the new standard.

----------------------------------------------
** IT / INTERNET / E-MAIL News **

Can you beat jet lag with a smartphone app?
http://mnt.to/l/4mFP
Those of us who have been on long-haul flights will have endured jet lag. Now, researchers have created a smartphone app that they say can help travelers quickly overcome it.

----------------------------------------------
** LITIGATION / MEDICAL MALPRACTICE News **

Malpractice and other insurance costs could change with Affordable Care Act
http://mnt.to/l/4mGr
The expansion of health insurance accomplished under the Affordable Care Act may alter costs for several major types of liability insurance, although any such changes are likely to be modest...

----------------------------------------------
** LIVER DISEASE / HEPATITIS News **

Gilead announces results from study of Sovaldi&reg; for retreatment of chronic hepatitis C in patients not cured with prior antiviral therapy
http://mnt.to/l/4mJ5
Gilead Sciences, Inc. has announced results from an open-label clinical trial (Study GS-US-334-0109) evaluating once-daily Sovaldi&reg; (sofosbuvir) 400 mg tablets for the retreatment of...

Report reveals new hepatitis C treatments will require patient-centric adherence support
http://mnt.to/l/4mHf
The arrival of new oral drugs for treatment of hepatitis C will dramatically shift the landscape of therapy from being physician-driven to patient-led, raising questions about best practices...

----------------------------------------------
** LYMPHOMA / LEUKEMIA / MYELOMA News **

Treatment-resistant leukemias may be vulnerable to experimental drug
http://mnt.to/l/4mGf
Research in mice and human cell lines has identified an experimental compound dubbed TTT-3002 as potentially one of the most potent drugs available to block genetic mutations in cancer cells...

----------------------------------------------
** MEDICAL DEVICES / DIAGNOSTICS News **

Proteomics International biomarker study moves closer to a CDx test for diabetic kidney disease
http://mnt.to/l/4mJ9
Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein...

A U.S. first - new technology allows full-body MRI for pacemaker patient
http://mnt.to/l/4mHN
Providence Saint Joseph Medical Center is the first hospital in the nation to conduct an MRI scan of a patient implanted with a new MRI-compatible pacemaker - a breakthrough because metal...

MRF Meningococcus Genome Library aids development of new typing test for meningococcal bacteria
http://mnt.to/l/4mH8
New research published in PLoS ONE has used data from the Meningitis Research Foundation (MRF) Meningococcus...

Can you beat jet lag with a smartphone app?
http://mnt.to/l/4mFP
Those of us who have been on long-haul flights will have endured jet lag. Now, researchers have created a smartphone app that they say can help travelers quickly overcome it.

----------------------------------------------
** MELANOMA / SKIN CANCER News **

Copper starvation could be promising treatment for some cancers
http://mnt.to/l/4mJc
Researchers who found some cancers caused by a mutation in the BRAF gene need copper to fuel tumor growth, suggest they may be treatable with drugs that block copper absorption.

Moffitt Cancer Center begins Phase I clinical trial of new immunotherapy
http://mnt.to/l/4mHq
Moffitt Cancer Center has initiated a phase I clinical trial for a new immunotherapy drug, ID-G305, made by Immune Design.

Dabrafenib assessed in comparison with vemurafenib: no added benefit
http://mnt.to/l/4mH5
Results from indirect comparison did not allow any reliable conclusionsDabrafenib (trade name: Tafinlar) has been approved since August 2013 for the treatment of advanced melanoma.

Targeting cancer's thirst for copper
http://mnt.to/l/4mGN
Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer, researchers at Duke Medicine report.

----------------------------------------------
** MENTAL HEALTH News **

Obsessive-compulsive disorder may reflect a propensity for bad habits
http://mnt.to/l/4mJ2
Two new studies published in Biological Psychiatry shed light on the propensity for habit formation in obsessive-compulsive disorder (OCD).

Adoption breakdown rate and the experiences of adoptive families in crisis in England
http://mnt.to/l/4mH2
The most comprehensive study ever to be carried out into adoption in England has confirmed that the rate of breakdown is lower than anticipated, but it also reveals a stark picture of the...

Psychological distress frequently experienced by civilians working with military in war zones
http://mnt.to/l/4mGX
The punishing psychological toll endured by military personnel in war zones has been extensively documented for years by researchers, perhaps more than ever in the wake of recent military...

----------------------------------------------
** MRI / PET / ULTRASOUND News **

A U.S. first - new technology allows full-body MRI for pacemaker patient
http://mnt.to/l/4mHN
Providence Saint Joseph Medical Center is the first hospital in the nation to conduct an MRI scan of a patient implanted with a new MRI-compatible pacemaker - a breakthrough because metal...

----------------------------------------------
** MRSA / DRUG RESISTANCE News **

New technique using DNA data could help doctors treat MRSA
http://mnt.to/l/4mGL
A team of scientists led by the University of Bath has developed a new technique to predict the toxicity of an MRSA infection from its DNA sequence.

----------------------------------------------
** NEUROLOGY / NEUROSCIENCE News **

How do our brains differentiate information about places and faces?
http://mnt.to/l/4mJY
Neuroscientists investigate 'object-based attention,' which allows us to pick a face we recognize out of a crowd, and find it is produced by three synchronized brain regions.

Neurofinance study confirms that financial decisions are made on an emotional basis
http://mnt.to/l/4mJ3
The willingness of decision makers to take risks increases when they play games of chance with money won earlier.

Development of individual cranial bones influenced by brain size
http://mnt.to/l/4mHc
Embryonic development in animals - except mice and rats - remains largely unexplored.

Oxidative damage to neurons alleviated by polysaccharides from Angelica sinensis
http://mnt.to/l/4mH9
According to traditional Chinese medicine, the roles of Angelica sinensis correlate with tonifying the blood and promoting its circulation.

660 nm red light-enhanced bone marrow mesenchymal stem cell transplantation for hypoxic-ischemic brain damage
http://mnt.to/l/4mH7
A series of previous studies suggested that the neuronal differentiation rate of bone marrow mesenchymal stem cells during the in vitro culture reached 78-92%, but their in vivo transplantation...

During prenatal brain development lipid levels impact autism
http://mnt.to/l/4mGj
In a groundbreaking York University study, researchers have found that abnormal levels of lipid molecules in the brain can affect the interaction between two key neural pathways in early...

----------------------------------------------
** NUTRITION / DIET News **

Sugary drink warning labels win key legislative victory in California
http://mnt.to/l/4mHW
Safety warning labels on sodas and other sugary beverages sold in California came one step closer to reality today, when the powerful Senate Health Committee approved SB 1000 on a 5-2 vote.

A high-fat diet can increase risk of certain types of breast cancer
http://mnt.to/l/4mGS
High total and saturated fat intake were associated with greater risk of estrogen receptor- and progesterone receptor-positive (ER+PR+) breast cancer (BC), and human epidermal growth factor 2...

International debate on genetically modified crops
http://mnt.to/l/4mGs
One of the world's most contentious food issues - Genetically Modified (GM) crops - was debated by some of the world's leading authorities on the subject at Queen's University Belfast.

----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **

Improving cognition later in life through physical activity
http://mnt.to/l/4mGZ
Physical activity in midlife seems to protect from dementia in old age, according to a study carried out at the University of Eastern Finland.

Consuming high-calorie foods may lead to brown fat cell 'whitening'
http://mnt.to/l/4mGV
Boston University researchers have learned new information about the consequences of overeating high-calorie foods.

Protein identified in fat and liver cells that can be altered to increase energy expenditure could lead to new obesity treatment
http://mnt.to/l/4mGQ
By manipulating a biochemical process that underlies cells' energy-burning abilities, investigators at Beth Israel Deaconess Medical Center (BIDMC) have made a novel discovery that could lead to...

A good patient-clinician relationship can improve health outcomes
http://mnt.to/l/4mGP
A meta-analysis of studies that investigated measures designed to improve health professionals' interactions with patients confirms that such efforts can produce health effects just as...

----------------------------------------------
** PAIN / ANESTHETICS News **

Prolotherapy: nonsurgical treatment for knee osteoarthritis
http://mnt.to/l/4mGd
A new nonsurgical approach to treating chronic pain and stiffness associated with knee osteoarthritis has demonstrated significant, lasting improvement in knee pain, function, and stiffness.

----------------------------------------------
** PARKINSON'S DISEASE News **

Research targets Parkinson's, Huntington's, other proteasomal diseases
http://mnt.to/l/4mG7
Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated in...

----------------------------------------------
** PEDIATRICS / CHILDREN'S HEALTH News **

Breastfeeding while on antidepressants: 'benefits outweigh risks'
http://mnt.to/l/4mJS
Though women who breastfeed are typically warned that medications can enter breast milk, new research suggests the benefits of remaining on antidepressants outweigh the risks.

Phase 3 results announced for paediatric study of investigational therapy Eloctate<sup>(TM)</sup> for haemophilia A
http://mnt.to/l/4mJ7
Biogen Idec and Swedish Orphan Biovitrum AB (Sobi) have released positive top-line results of the Kids A-LONG Phase 3 clinical study that evaluated the safety and efficacy of Eloctate(TM), an...

Scripps Florida Scientists win grant to study how exposure to prescription pain medication in the womb affects developing brain
http://mnt.to/l/4mHJ
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $472,500 Cutting Edge Basic Research Award (CEBRA) by the National Institute on Drug Abuse...

Are babies who wake to breastfeed at night trying to delay the birth of a sibling?
http://mnt.to/l/4mHd
In a new article published online in the journal Evolution, Medicine, and Public Health, Professor David Haig argues that infants that wake frequently at night to breastfeed are delaying the...

Adoption breakdown rate and the experiences of adoptive families in crisis in England
http://mnt.to/l/4mH2
The most comprehensive study ever to be carried out into adoption in England has confirmed that the rate of breakdown is lower than anticipated, but it also reveals a stark picture of the...

JCI: Visualizing calcium dynamics in the kidney, Characterization of an asplenic patient with disorder of sexual development
http://mnt.to/l/4mGT
Visualizing calcium dynamics in the kidneyIn this issue of the Journal of Clinical Investigation, Janos Peti-Peterdi and colleagues at the University of Southern California used multiphoton...

New technique using DNA data could help doctors treat MRSA
http://mnt.to/l/4mGL
A team of scientists led by the University of Bath has developed a new technique to predict the toxicity of an MRSA infection from its DNA sequence.

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** PHARMA INDUSTRY / BIOTECH INDUSTRY News **

Report reveals new hepatitis C treatments will require patient-centric adherence support
http://mnt.to/l/4mHf
The arrival of new oral drugs for treatment of hepatitis C will dramatically shift the landscape of therapy from being physician-driven to patient-led, raising questions about best practices...

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** PREGNANCY / OBSTETRICS News **

Breastfeeding while on antidepressants: 'benefits outweigh risks'
http://mnt.to/l/4mJS
Though women who breastfeed are typically warned that medications can enter breast milk, new research suggests the benefits of remaining on antidepressants outweigh the risks.

Scripps Florida Scientists win grant to study how exposure to prescription pain medication in the womb affects developing brain
http://mnt.to/l/4mHJ
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $472,500 Cutting Edge Basic Research Award (CEBRA) by the National Institute on Drug Abuse...

During prenatal brain development lipid levels impact autism
http://mnt.to/l/4mGj
In a groundbreaking York University study, researchers have found that abnormal levels of lipid molecules in the brain can affect the interaction between two key neural pathways in early...

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** PRIMARY CARE / GENERAL PRACTICE News **

Report reveals new hepatitis C treatments will require patient-centric adherence support
http://mnt.to/l/4mHf
The arrival of new oral drugs for treatment of hepatitis C will dramatically shift the landscape of therapy from being physician-driven to patient-led, raising questions about best practices...

A good patient-clinician relationship can improve health outcomes
http://mnt.to/l/4mGP
A meta-analysis of studies that investigated measures designed to improve health professionals' interactions with patients confirms that such efforts can produce health effects just as...

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** PSYCHOLOGY / PSYCHIATRY News **

Neurofinance study confirms that financial decisions are made on an emotional basis
http://mnt.to/l/4mJ3
The willingness of decision makers to take risks increases when they play games of chance with money won earlier.

Obsessive-compulsive disorder may reflect a propensity for bad habits
http://mnt.to/l/4mJ2
Two new studies published in Biological Psychiatry shed light on the propensity for habit formation in obsessive-compulsive disorder (OCD).

Love is a many-faceted thing
http://mnt.to/l/4mHv
Regular churchgoers, married people or those who enjoy harmonious social ties are most satisfied with their love life.

Life-space mobility, quality of life, determined by physical function and sense of autonomy in older people
http://mnt.to/l/4mH4
Physical function and sense of autonomy are independent determinants of life-space mobility in older people.

Adoption breakdown rate and the experiences of adoptive families in crisis in England
http://mnt.to/l/4mH2
The most comprehensive study ever to be carried out into adoption in England has confirmed that the rate of breakdown is lower than anticipated, but it also reveals a stark picture of the...

Psychological distress frequently experienced by civilians working with military in war zones
http://mnt.to/l/4mGX
The punishing psychological toll endured by military personnel in war zones has been extensively documented for years by researchers, perhaps more than ever in the wake of recent military...

Rapid antidepressant effect in depression achieved with intranasal ketamine
http://mnt.to/l/4mGn
A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant...

Research linked to stress in mice confirms blood-brain comparison is valid
http://mnt.to/l/4mGm
Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone - and showing signs of anxiety - are...

Innovative, coordinated brain care could save billions of health care dollars
http://mnt.to/l/4mGb
Studies have shown that a new patient and caregiver centered model of innovative, coordinated brain care for older adults improves health outcomes and quality of care for those with cognitive...

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** PUBLIC HEALTH News **

Study questions safety thresholds for hormone-disrupting chemicals
http://mnt.to/l/4mJT
Current human safety levels for exposure to endocrine-disrupting chemicals are based on studies of rodent models. But new research has now questioned the accuracy of this method.

Sugary drink warning labels win key legislative victory in California
http://mnt.to/l/4mHW
Safety warning labels on sodas and other sugary beverages sold in California came one step closer to reality today, when the powerful Senate Health Committee approved SB 1000 on a 5-2 vote.

Risks from refrigerant in cars may outweigh the benefits
http://mnt.to/l/4mGY
The refrigerant R1234yf is being considered for use in air conditioning systems in cars.

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** RESPIRATORY / ASTHMA News **

Genkyotex's GKT137831 found to reverse fibrosis and improve survival in a model of persistent lung fibrosis
http://mnt.to/l/4mJ6
Genkyotex, the leading developer of selective NOX enzyme inhibitors, has announced the publication of data showing that GKT137831, a first in class NOX1 and 4 inhibitor, was able to reverse...

Risks from refrigerant in cars may outweigh the benefits
http://mnt.to/l/4mGY
The refrigerant R1234yf is being considered for use in air conditioning systems in cars.

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** SENIORS / AGING News **

Genkyotex's GKT137831 found to reverse fibrosis and improve survival in a model of persistent lung fibrosis
http://mnt.to/l/4mJ6
Genkyotex, the leading developer of selective NOX enzyme inhibitors, has announced the publication of data showing that GKT137831, a first in class NOX1 and 4 inhibitor, was able to reverse...

Life-space mobility, quality of life, determined by physical function and sense of autonomy in older people
http://mnt.to/l/4mH4
Physical function and sense of autonomy are independent determinants of life-space mobility in older people.

Potential target identified to combat muscle wasting
http://mnt.to/l/4mH3
The pathological atrophy of skeletal muscle is a serious biomedical problem for which no effective treatment is currently available.

Improving cognition later in life through physical activity
http://mnt.to/l/4mGZ
Physical activity in midlife seems to protect from dementia in old age, according to a study carried out at the University of Eastern Finland.

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** SEXUAL HEALTH / STDS News **

Love is a many-faceted thing
http://mnt.to/l/4mHv
Regular churchgoers, married people or those who enjoy harmonious social ties are most satisfied with their love life.

JCI: Visualizing calcium dynamics in the kidney, Characterization of an asplenic patient with disorder of sexual development
http://mnt.to/l/4mGT
Visualizing calcium dynamics in the kidneyIn this issue of the Journal of Clinical Investigation, Janos Peti-Peterdi and colleagues at the University of Southern California used multiphoton...

HIV/STI prevention: the double whammy of multiple sex partners and drinking
http://mnt.to/l/4mGk
The cartoon character Homer J. Simpson once said "Alcohol: The source of, and solution to, all of life's problems.

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** SLEEP / SLEEP DISORDERS / INSOMNIA News **

Are babies who wake to breastfeed at night trying to delay the birth of a sibling?
http://mnt.to/l/4mHd
In a new article published online in the journal Evolution, Medicine, and Public Health, Professor David Haig argues that infants that wake frequently at night to breastfeed are delaying the...

Can you beat jet lag with a smartphone app?
http://mnt.to/l/4mFP
Those of us who have been on long-haul flights will have endured jet lag. Now, researchers have created a smartphone app that they say can help travelers quickly overcome it.

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** STEM CELL RESEARCH News **

660 nm red light-enhanced bone marrow mesenchymal stem cell transplantation for hypoxic-ischemic brain damage
http://mnt.to/l/4mH7
A series of previous studies suggested that the neuronal differentiation rate of bone marrow mesenchymal stem cells during the in vitro culture reached 78-92%, but their in vivo transplantation...

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** STROKE News **

Oxidative damage to neurons alleviated by polysaccharides from Angelica sinensis
http://mnt.to/l/4mH9
According to traditional Chinese medicine, the roles of Angelica sinensis correlate with tonifying the blood and promoting its circulation.

660 nm red light-enhanced bone marrow mesenchymal stem cell transplantation for hypoxic-ischemic brain damage
http://mnt.to/l/4mH7
A series of previous studies suggested that the neuronal differentiation rate of bone marrow mesenchymal stem cells during the in vitro culture reached 78-92%, but their in vivo transplantation...

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** UROLOGY / NEPHROLOGY News **

Proteomics International biomarker study moves closer to a CDx test for diabetic kidney disease
http://mnt.to/l/4mJ9
Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein...

JCI: Visualizing calcium dynamics in the kidney, Characterization of an asplenic patient with disorder of sexual development
http://mnt.to/l/4mGT
Visualizing calcium dynamics in the kidneyIn this issue of the Journal of Clinical Investigation, Janos Peti-Peterdi and colleagues at the University of Southern California used multiphoton...

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** WATER - AIR QUALITY / AGRICULTURE News **

Study questions safety thresholds for hormone-disrupting chemicals
http://mnt.to/l/4mJT
Current human safety levels for exposure to endocrine-disrupting chemicals are based on studies of rodent models. But new research has now questioned the accuracy of this method.

International debate on genetically modified crops
http://mnt.to/l/4mGs
One of the world's most contentious food issues - Genetically Modified (GM) crops - was debated by some of the world's leading authorities on the subject at Queen's University Belfast.

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** WOMEN'S HEALTH / GYNECOLOGY News **

Lab-grown nostril and vagina constructed with similar techniques
http://mnt.to/l/4mHb
Scientists have engineered human cartilage for nostril reconstruction, while another team has grown artificial vaginas - both procedures used cells from the patients' own bodies.

Female drinkers face greater risks to their health from alcohol consumption
http://mnt.to/l/4mGW
The increased risk of death associated with alcohol intake is not the same for men and women. A study that compared the amount of alcohol consumed and death from all causes among nearly 2.

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