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13.22 Carat 'The Blue' Diamond Set to Fetch 21 Million Dollars at Auction

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The Blue, the world's largest flawless fancy vivid blue diamond is set to go under hammer next month and the experts have predicted it to fetch up to 15 million pounds to 21 million dollars. Christie's New York is set to auction the 13.22 carat diamond, Sky News reported. Rahul Kadakia, Head of Jewellery for Christie's Americas and Switzerland, said the stone is internally and externally bereft of any imperfections, asserting that it was the best blue ...

Vienna's Philharmonic Orchestra to Return Nazi Looted Painting

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In the latest high-profile restitution case in Austria, Vienna's Philharmonic Orchestra said that it was returning a painting that was stolen by the Nazis to the descendants of its rightful owners. The Philharmonic, famed for its annual New Year's concert, sent a letter to the descendants of the painting's former French owner Marcel Koch on Thursday to inform them of the move, a spokeswoman said. The 1883 painting "Port-en-Bessin" by French artist Paul ...

Fruit Flies Antennae Help Them Cruise Through Wind

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Scientists have discovered the mechanism used by fruit flies to regulate their flight speed from their antennae by using both vision and wind-sensing information. The researchers traced the flies' flight trajectories in a wind tunnel and found that the wind-sensing antennae stabilize the fly's visual flight controller. The results showed that in gusts, air drag causes part of the deceleration, but in addition, antennae sense airspeed changes and induce ...

Facebook to Punish Pages Asking for Likes, Shares

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Facebook is reportedly planning to punish pages that bait users into liking and sharing content, reveals the company. The move is seen as an attempt by the social network to clean up users' News Feed. According to Tech Crunch, while there are more and more Pages and friends competing for the finite amount of time people spend reading the feed, increasing competition plus limited attention equals decreasing reach. Meanwhile, the social network ...

Study Explains How Brain Chooses to Focus on Some Faces and Ignore Others

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A new study has explained how the brain chooses/decides what to pay attention too and what to merely monitor and ignore. MIT neuroscientists found that a part of the prefrontal cortex known as the inferior frontal junction (IFJ) controls visual processing areas that are tuned to recognize a specific category of objects. Scientists know much less about this type of attention, known as object-based attention, than spatial attention, which involves focusing ...

Scientists Reveal New Aspect of Autism

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A team of researchers has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known. The research took place at the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology (CCSB) at the Dana-Farber Cancer Institute. These interactions had not been detected earlier because they involve alternatively spliced forms of autism genes found in the brain. ...

Older People With Memory and Thinking Problems May Have Lower Risk of Cancer Death

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Older people who have memory and thinking problems, but do not yet have dementia may have a lower risk of dying from cancer than people who have no memory and thinking problems. This is according to a study published in the April 9, 2014, online issue of iNeurology/iA (Regd) , the medical journal of the American Academy of Neurology. "Studies have shown that people with Alzheimer''s disease are less likely to develop cancer, but we don''t know the reason ...

Regular Exercise may Slow Down Aging

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In humans, regular physical activity can slow down the aging process. The study found that regular exercise not only improves the quality of life but can also extend a person's lifespan by up to five years. The study by Canadian sports medicine physician Mark Tarnopolsky also revealed that older adults receive the most benefits when combining endurance exercise with resistance exercise. The study was presented at the 23rd Annual Meeting ...

A Woman Who Has 'uncontrollable' Orgasms 50 Times a Day

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Once-Daily Combination to Treat HCV Genotype 1 Patients: Impressive SVR12 Data

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Results from three Phase III clinical trials (ION-1, ION-2 and ION-3) have been presented at the International Liver CongressTM 2014. The study was about evaluating the investigational once-daily fixed-dose combination of the nucleotide analogue polymerase inhibitor sofosbuvir (SOF) 400mg and the NS5A inhibitor ledipasvir (LDV) 90mg, with and without ribavirin (RBV), for the treatment of genotype 1 chronic hepatitis C virus (HCV) infection. "With cure rates well ...

Improving Patient Outcomes With New Advances in HCC; Diagnosis, Staging and Treatment All Predicted

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The epidemiological, genetic and clinical data presented today are collectively focused on various approaches designed to improve the diagnosis, staging and treatment of hepatocellular carcinoma (HCC). This data was presented at the International Liver CongressTM 2014 "Human hepatocellular carcinoma is one of the most prevalent cancers worldwide and the second most frequent cause of cancer-related death," said EASL's Scientific Committee Member Dr Helen Reeves Senior ...

HCV Genotype 4 Patients With Simeprevir- And Sofosbuvir-Based Regimens: New Data

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Simeprevir 150 mg once-daily for 12 weeks in combination with peginterferon and ribavirin (followed by 12 or 36 weeks of peginterferon and ribavirin) was effective and well tolerated in hepatitis C virus (HCV) genotype 4-infected patients, consistent with previous observations in HCV genotype 1-infected patients. These results were found from RESTORE, a phase III, multicentre, single-arm, open-label study presented today at the International Liver CongressTM 2014. Overall, ...

High SVR Achieved With New Interferon-Free All-Oral 3D Regimen in Chronic HCV Genotype 1 Patients

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High rates of virological response in patients chronically infected with hepatitis C virus genotype 1, with new interferon-free, all-oral, three direct-acting-antiviral treatment regimen in development by AbbVie, suggests results of three studies presented today at the International Liver CongressTM 2014. The 3D regimen consists of the HCV NS3/4A protease inhibitor ABT-450 dosed with ritonavir, the NS5A inhibitor ABT-267, and the NS5B RNA polymerase inhibitor ...

Virus-fighting Genes Linked to Cancer Mutations

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New research has confirmed the role of a group of virus-fighting genes in the development of cancer. Our understanding of the biological processes that cause cancer is limited. UV light and smoking are two well-understood cancer-causing processes. Exposure to either of these processes causes distinguishable patterns of genetic damage, or 'signatures', on the genome that can lead to cancer. All cancer-causing processes leave their own distinct imprint or signature, ...

Study Measures Safety, Effectiveness of Spinal Surgery

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The need for quality registries has become central to emerging evidence-driven reforms, with Americans spending an estimated (Dollar) 850 billion annually on ineffective medical treatment. And while many studies have demonstrated the efficacy of various surgical procedures for spinal disorders, few have examined their effectiveness in real-world settings or at the individual level. A team of researchers led by Anthony L. Asher, MD, FAANS, has reviewed a nationwide, ...

Researchers Use Genome Sequencing of MRSA Infection to Predict Disease Severity

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The spread of the antibiotic-resistant pathogen MRSA (methicillin-resistant iStaphylococcus aureus/i) remains a concerning public health problem. This is especially among doctors who are trying to determine appropriate treatment options for infected patients. Bacterial pathogens, such as MRSA, cause disease in part due to toxicity, or the bacterium's ability to damage a host's tissue. In a study published online in iGenome Research/i, researchers ...

New Class of Agents Burst Through 'Superbug' Defenses to Fight Antibiotic Resistance

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Scientists have discovered a class of agents, in the fight against "superbugs," that can make some of the most notorious strains vulnerable to the same antibiotics that they once handily shrugged off. The report on the promising agents called metallopolymers appears in the iJournal of the American Chemical Society/i. Chuanbing Tang and colleagues note that the antibiotic-resistant bacteria known as MRSA (methicillin-resistant iStaphylococcus ...

Rabbits Kept Indoors may Suffer from Lack of Vitamin D

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Researchers report in a new study that rabbits that remain indoors may suffer from a lack of vitamin D. In rabbits kept as pets or used in laboratory studies, the deficiency could lead to dental problems, undermine their cardiovascular health, weaken their immune systems and skew scientific findings. The study found that regular exposure to artificial ultraviolet B light for two weeks doubled rabbits' serum vitamin D levels - an increase not seen in ...

Can Animals Really Help People in Hospitals?

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Many people have an opinion on whether animals can help to improve well-being and care for patients in hospitals. Does anyone really know whether there are benefits both for the patients and the animals themselves? Not according to a team of researchers from the University of Adelaide, which has conducted a worldwide review of all studies looking at the impact of "animal interventions" in healthcare settings for children. The researchers, ...

Strategy Needed to Control Non-Communicable Diseases

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Experts said that there is a need for a coherent strategy to control non-communicable diseases in the country with a special focus on alcohol consumption. "It is important to think of a coherent strategy and put together overall policy framework for control of non-communicable diseases where alcohol and tobacco form the basis of a policy formulation," C.K. Mishra, additional secretary in the health ministry said at a consultation on alcohol control here. ...

Chinese Herb Extract has Antioxidative and Neuroprotective Effects

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The roles of iAngelica sinensis/i correlate with tonifying the blood and promoting its circulation, suggests traditional Chinese medicine. The plant also known as dong quai or female ginseng is a herb with medicinal properties. Recent studies have shown that extracts of iAngelica sinensis/i have antioxidative and neuroprotective effects. However, the anti-oxidative function of iAngelica sinensis/i polysaccharide has rarely been addressed. In ...

Physical Function Determine Life-Space Mobility in Older People

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In older people, physical function and sense of autonomy are independent determinants of life-space mobility. This was found in a study conducted at the Gerontology Research Center of the University of Jyvaskyla. In this project, 848 older men and women that lived independently in the Jyvaskyla region in Central Finland were interviewed at their own home. Life-space mobility reflects a person's mobility with or without the use of a vehicle. Life-space ...

Researchers Examine Mental Health Toll Exacted on Civilians Working With Military

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In war zones, the punishing psychological toll endured by military personnel has been extensively documented for years by researchers, perhaps more than ever in the wake of recent military engagements in Iraq and Afghanistan. But there has been a troubling dearth of research examining the mental health toll exacted on the large numbers of civilians who work with the military in war zones. Sociologists Alex Bierman, an assistant professor at the University ...

WHO Urges Global Push to Increase Treatment of Hepatitis C

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The WHO called for a dramatic increase in screening and treatment of hepatitis C, saying higher demand would help drive down the cost of drugs for the disease. Most of the 185 million people chronically infected with the liver disease worldwide do not know they have it due to lack of screening, and many of those who do cannot access treatment due to the high cost, the UN agency said. Some 350,000 people die of hepatitis C-related liver diseases annually, ...

Obsessive Compulsive Disorder Common Across the Globe

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Are you obsessed about situations like imagine your house might be on fire or if your hands are clean as you attend a key client? You are not alone. According to a new global research, 94 percent of people experience unwanted, intrusive thoughts, images or impulses. Thoughts, images and impulses symptomatic of obsessive compulsive disorder (OCD) are widespread. "This study shows that it is not the unwanted, intrusive thoughts that are ...

Stick to Number 7 to Bring Luck Back in Your Life

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Do you believe in numerology? Try to stick to number 7 in whatever you plan next - from a new car to your first house - as a poll has declared 7 as the world's most favourite number. London-based author Alex Bellos, who revealed this based on an online survey of 44,000 people, said this may be because of the digit's religious significance. "The reason why a reverence for the number seven is a constant throughout human history can never be known, but, ...

Research Suggests Many With Prostate Cancer Misdiagnosed With Mild Form of Disease

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Researchers have revealed that a large proportion of prostate cancer patients are being misdiagnosed, with initial tests underestimating the aggressiveness of the disease. Prostate cancer is the most common cancer in men in Britain, killing around 10,800 men last year, but is relatively difficult to diagnose early due to its subtle symptoms and a reluctance among many men to visit a doctor. Advocacy group Cancer Research UK said University of Cambridge ...

Rare Fossilized Embryos Unearthed by Scientists

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Rare fossilized embryos, believed to be more than 500 million years old, have been unearthed by researchers at the University of Missouri. Fossilized records from the Cambrian Period, which occurred between 540 million and 485 million years ago, provide glimpses into evolutionary biology when the world's ecosystems rapidly changed and diversified. Most fossils show the organisms' skeletal structure, which may or may not give researchers accurate pictures ...

Gay Leaders from Developing Countries Meet World Bank Head

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In order to discuss the discrimination they face in their countries, gay leaders from developing countries held a private meeting with World Bank President Jim Yong Kim on Friday. Six weeks after the bank put a hold on a (Dollar) 90 million loan to Uganda due to its harsh anti-gay laws, Kim held talks with 15 lesbian, gay, bisexual and transgender (LGBT) leaders on mistreatement they suffer due to their sexual orientation. It was the first meeting of its kind ...

MERS Claims Life of Filipino Paramedic in UAE

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One of six Filipino paramedics in the UAE who have been infected by the MERS coronavirus has died from the respiratory disease, the UAE has confirmed. The announcement comes just days after a 24-hour shutdown of the emergency department at a major hospital in Saudi Arabia, where most cases have been reported, amid fears of a spread of the Middle East Respiratory Syndrome among medical staff. The UAE interior ministry said the six staff members worked ...

Polish Pope is Still a Rock Star

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John Paul II, the charismatic Polish pope who made a name for himself by circling the globe, was widely regarded by one and all worldwide. "He broke protocol. I know that security had trouble keeping an eye on him. He sometimes wandered off when he felt like it," Warsaw sociologist Pawel Boryszewski said of the soon-to-be saint who died in 2005. Throughout his 27-year papacy, the polyglot and onetime actor travelled to more than 100 countries, embracing ...

As Belief in Saints Endures, St Jude Continues to Rule the Roost

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For many Catholics, praying to the plethora of saints could be the solution if they have lost a wallet or are making a long, unknown journey. As millions of Catholics prepare for the canonisation of John Paul II, some may be wondering what role the multitude of saints in Catholicism can still play in the modern age. But for many Catholics -- who unlike Protestants and Muslims are not considered to have a direct connection to God -- the saints are important ...

Research Explores Effects of Sudden Loss of Consciousness

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Up to 3% of consultations at an emergency department concern a sudden loss of consciousness or near loss of consciousness, according to a prospective study (the SPEED Study) presented by Yvonne Greve of Nuremberg Hospital in Deutsches Arzteblatt Internationa. In order to assess the frequency and prognostic significance of near syncope and syncope (the specialist terms for short-term near or complete loss of consciousness), the authors gathered data on 395 patients ...

Targeted Cancer Therapies on the Anvil Following Brain Cell Discovery

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New research into the processes that control brain cell production could harbinger treatments for brain cancer and other brain-related disorders. Scientists have gained new understanding of the role played by a key molecule that controls how and when nerve and brain cells are formed - a process that allows the brain to develop and keeps it healthy. Their findings could help explain what happens when cell production goes out of control, which is a fundamental characteristic ...

Central Nervous System Development and Disease Affected by The Olig Family

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Research has shown that the oligodendrocyte transcription family (Olig family) is widely expressed in the central nervous system of various mammals. It plays a critical role in central nervous system development by controlling differentiation and maturation of oligodendrocytes, motor neurons and astrocytes. Moreover, accumulating evidence demonstrates Olig family participation in many central nervous system diseases. Therefore, based on current literature, ...

Music Has a Cost for Mexico's Hottest Drug Balladeer

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'EI Komander' a Mexican Singer who has faced bans for eulogizing drug lords struts on stage, pours expensive whisky into a fan's mouth and sings about grenade launchers. Wearing a black leather jacket and military fatigue pants, Alfredo Rios took his show to 5,500 people in Texcoco, in the state of Mexico, a region of 15 million people enduring a spike in murders this year. The man with the short-cropped hair and beard is among the most popular performers ...

Underground Cellar Introduces a Winning Online Game 'Fine Wines'

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'Fine Wines' is a winning online game introduced by Underground Cellar of getting more than you ask for when its comes to great wine. Startup founder Jeffrey Shaw playfully described it as "wine roulette," only you can't lose and the payout is cabernet sauvignon, merlot, chardonnay or other varietals crafted by renowned vineyards. "I was a technology guy; I sort of fell into wine," Shaw said while exploring undergroundcellar.com on an iPad. Shaw ...

Bird Flu Outbreak in Japan

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Confirmations of outbreak of Bird-flu infections by officials at a poultry farm in the south resulted in the slaughter of some 112,000 chickens in Japan. DNA tests confirmed the H5 strain of the virus at a farm in Kumamoto prefecture that kept 56,000 birds, after its owner reported Saturday a lot of sudden deaths among his poultry, the agriculture ministry said in a statement. Officials also ordered the culling of another 56,000 birds at a separate farm ...

Dilemma Time for Ukrainians in Russia

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It has emerged that Ukrainians in Russia have found themselves thrust into the heart of the standoff between Moscow and Kiev. They are having to confront both their own divided loyalties and fears of rising Russian hostility toward them. "The situation is tragic. My life has been split in two, I cannot choose between my two eyes," Nina Kibrik, who was born in Moscow to Ukrainian parents, told AFP. The tension between pro-Europeans and pro-Russians in ...

Policy Paper on Medical Liability Crisis Released by American College of Physicians

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A policy paper on the medical liability crisis, which continues to have a profound effect on the medical system, has been released by the American College of Physicians (ACP). "Medical Liability Reform-Innovative Solutions for a New Health Care System" provides an update of the medical liability landscape, state-based activity on medical liability reform, and summarizes traditional and newer reform proposals and their ability to affect system efficiency and encourage ...

Research Reveals How the Brain Pays Attention

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In order to pick out a face in the crowd, your brain has to retrieve the memory of the face you are seeking, then hold it in place while scanning the crowd, paying special attention to finding a match. A new study by MIT neuroscientists reveals how the brain achieves this type of focused attention on faces or other objects: A part of the prefrontal cortex known as the inferior frontal junction (IFJ) controls visual processing areas that are tuned to recognize a ...

Novel Medications may Come About Thanks to New Cell Models for Tracking Body Clock Gene Function

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It is obvious that the consequences of modern life such as shift work, cell phone addiction, and travel across time zones disturb internal clocks. These are found in the brain where they regulate sleep and throughout the body where they regulate physiology and metabolism. Disrupting the clocks is called circadian misalignment, which has been linked to metabolic problems, even in healthy volunteers. Researchers from the Perelman School of Medicine at ...

Study Shows How Gardening can Help Overcome Blues

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Gardening can help in treating the blues and proves effective in treating drug addicts, soldiers with post-traumatic stress disorder, say scientists. Sir Richard Thompson, president of the Royal College of Physicians, said that more doctors should promote gardening therapy, which not just benefits the patients, but also creates "huge potential savings for the NHS", the Independent reported. The researchers have also said that just looking at a garden ...

Gene Expression is Hindered When Tumor-Suppressor Connects With Histone Protein

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A team led by scientists at The University of Texas MD Anderson Cancer Center has found that a tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that's tightly intertwined with DNA, according to the research reported at the AACR Annual Meeting 2014. The findings, also published in the journal Nature on April 10, provide evidence in support of the "histone ...

Pandemics Could be Prevented by Insights into How a Bird Flu Virus Spreads

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Despite the fact that the virus cannot spread easily between people, the H5N1 bird flu virus has infected and killed hundreds of people. The death toll could become much worse if the virus became airborne. A study published by Cell Press April 10th in the journal emCell/em has revealed a minimal set of mutations allowing H5N1 to be transmitted through the air from one ferret to another. The findings will be invaluable for future surveillance programs and may ...

Getting to the Root of Parkinson's Disease

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Researchers at Johns Hopkins have identified a biological process that appears to trigger a particular form of Parkinson's disease present in a large number of patients. The researchers worked with human neurons and fruit flies. A report on the study, in the April 10 issue of the journal iCell/i, could lead to new treatments for this disorder. "Drugs such as L-dopa can, for a time, manage symptoms of Parkinson's disease, but as the disease worsens, ...

Wearable Electronic Devices may Operate on Thermoelectric Generator on Glass Fabric

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From smart watches to smart glasses to smart pacemakers, wearable computers or devices are the next big thing in the health industry. For electronics to be worn by a user, they must be light, flexible, and equipped with a power source, which could be a portable, long-lasting battery or no battery at all but a generator. How to supply power in a stable and reliable manner is one of the most critical issues to commercialize wearable devices. A team ...

Researchers Discover Lactate Metabolism Target That Halts Growth in Lung Cancer Model

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Previous research has revealed that cancer cells generate energy differently than normal cells, a characteristic that helps them to survive and spread. A major goal in the field of cancer metabolism is to find ways to overcome this survival advantage. Now a research team led by investigators in the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC) has found that targeting the enzyme responsible for the final step of glucose metabolism not ...

Mechanism by Which Lung Function is Regulated in Birt-Hogg-Dube Syndrome Determined by Penn Researchers

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The tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, according to researchers at Penn Medicine. The latter is a genetic disorder that affects the lungs, skin and kidneys. Folliculin''s absence or mutated state has a cascading effect that leads to deteriorated lung integrity and an impairment of lung function, as reported in their findings in the current issue of iCell ...