Dear kostik,
Welcome to today's Medical News Today newsletter, containing the most recent headlines from your chosen news categories.
----------------------------------------------
** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **
Does marijuana use cause sleep problems?
http://mnt.to/l/4nFw
New research due to be presented at SLEEP 2014 finds an association between marijuana use and impaired sleep, but it cannot determine causality.
----------------------------------------------
** ANXIETY / STRESS News **
Psychiatric comorbidities are common in people with epilepsy, but underestimated and often untreated
http://mnt.to/l/4nFx
"Up to 60 percent of people with epilepsy suffer from psychiatric comorbidities such as anxiety or depression, but the situation is still not getting the attention it deserves.
The appeal of well-being applications often short-lived: Finnish study
http://mnt.to/l/4nD3
According to a doctoral thesis by Research Scientist Kirsikka Kaipainen from VTT Technical Research Centre of Finland, online and mobile applications for stress management and healthy eating...
Unexpected death of a loved one linked to onset of psychiatric disorders
http://mnt.to/l/4nCF
The sudden loss of a loved one can trigger a variety of psychiatric disorders in people with no history of mental illness, according to researchers at Columbia University's Mailman School of...
----------------------------------------------
** ARTHRITIS / RHEUMATOLOGY News **
FDA approves first generic versions of celecoxib
http://mnt.to/l/4nFj
The U.S. Food and Drug Administration has approved the first generic versions of Celebrex (celecoxib) capsules, a treatment for rheumatoid arthritis, osteoarthritis, short-term (acute) pain...
----------------------------------------------
** BIOLOGY / BIOCHEMISTRY News **
Scientists discover how deadly ebola virus 'punches' its way into human cells
http://mnt.to/l/4nFy
At first, cells contain the ebola virus in a vesicle awaiting disposal, but the pH level of the vesicle triggers the virus to make a molecular fist and it punches its way out.
----------------------------------------------
** BONES / ORTHOPEDICS News **
A major step towards better diagnosis and treatment of osteoporosis
http://mnt.to/l/4nD5
A new target that may be critical for the treatment of osteoporosis, a disease which affects about 25% of post-menopausal women, has been discovered by a group of researchers in The Netherlands...
----------------------------------------------
** BREAST CANCER News **
New treatment option for young women with hormone-sensitive breast cancer
http://mnt.to/l/4nFk
The aromatase inhibitor exemestane is more effective than tamoxifen in preventing breast cancer recurrence in young women who also receive ovarian function suppression as adjuvant...
Study finds risk of recurrence low in smallest HER2+ breast cancer tumors
http://mnt.to/l/4nFh
Patients with specific HER2+ breast cancer tumors had a low risk of the cancer recurring five years after diagnosis, even without chemotherapy or treatment with a common antibody, according to...
Many breast cancer patients don't get treatment for heart problems
http://mnt.to/l/4nCf
Only a third of older breast cancer patients saw a cardiologist within 90 days of developing heart problems, in a study presented at the American Heart Association's Quality of Care and...
----------------------------------------------
** CANCER / ONCOLOGY News **
Patients with terminal illnesses benefit from stopping statins
http://mnt.to/l/4nGq
Cholesterol-lowering statins are widely used, but new research suggests patients in late stages of terminal illnesses may extend their lives by discontinuing use of the drug.
Reduced kidney function associated with higher risk of renal and urothelial cancer
http://mnt.to/l/4nF4
A key measure of reduced kidney function and chronic kidney disease - reduced glomerular filtration rate - is an independent risk factor for renal and urothelial cancer, according to a study...
Advanced bladder cancer patients benefit from immune therapy
http://mnt.to/l/4nDv
A multi-center phase I study using an investigational drug for advanced bladder cancer patients who did not respond to other treatments has shown promising results in patients with certain tumor...
It is estimated that there will be nearly 19 million cancer survivors in the U.S by 2024
http://mnt.to/l/4nDt
The number of cancer survivors in the United States, currently estimated to be 14.5 million, will grow to almost 19 million by 2024, according to an updated report by the American Cancer Society.
Potential dangers of chemotherapy regimen for bladder cancer patients uncovered by trial
http://mnt.to/l/4nDs
Patients with muscle-invasive bladder cancer often benefit from chemotherapy before surgery to remove the tumor, but a test of one regimen by researchers at Fox Chase Cancer Center was halted...
New clinical guidelines for cancer-related fatigue
http://mnt.to/l/4nDp
Fatigue is a debilitating problem for cancer patients undergoing treatment; however, it also poses a huge detriment after treatment and can significantly affect quality of life.
Overall survival benefit shown for patients with stage III soft tissue sarcomas
http://mnt.to/l/4nDj
Fox Chase Cancer Center researchers have carried out the first retrospective analysis of adjuvant chemotherapy's impact on overall survival in patients with stage III soft tissue sarcomas (STS)...
Bladder cancer patients carrying three specific mutations benefit from early chemotherapy
http://mnt.to/l/4nDc
Three genetic changes can predict whether a patient will benefit from chemotherapy before surgery to remove bladder cancer, according to new findings presented by Fox Chase Cancer Center...
----------------------------------------------
** CARDIOVASCULAR / CARDIOLOGY News **
For older adults with pneumonia, treatment including azithromycin associated with lower risk of death, small increased risk of heart attack
http://mnt.to/l/4nF9
In a study that included nearly 65,000 older patients hospitalized with pneumonia, treatment that included azithromycin compared with other antibiotics was associated with a significantly...
Preventive placement of ICDs in patients with less severe heart failure associated with improved survival
http://mnt.to/l/4nF8
An examination of the benefit of preventive placement of implantable cardioverter-defibrillators (ICDs) in patients with a less severe level of heart failure, a group not well represented in...
'Off-pump' heart bypass surgery may reduce risk of postoperative kidney injury, although no improvement in long-term function
http://mnt.to/l/4nF6
Among patients undergoing coronary artery bypass graft (CABG) surgery, those who were not put on a heart-lung machine (off-pump) had a reduced risk of postoperative kidney injury compared to...
Potential dangers of chemotherapy regimen for bladder cancer patients uncovered by trial
http://mnt.to/l/4nDs
Patients with muscle-invasive bladder cancer often benefit from chemotherapy before surgery to remove the tumor, but a test of one regimen by researchers at Fox Chase Cancer Center was halted...
Community program helps lower blood pressure among minorities
http://mnt.to/l/4nCS
Minorities at a higher risk of developing hypertension used a community-based program to significantly lower their blood pressure, researchers said at the American Heart Association's Quality...
More than 10 percent of heart attack patients may have undiagnosed diabetes
http://mnt.to/l/4nCh
At least 10 percent of people who have a heart attack may have undiagnosed diabetes, according to new research presented at the American Heart Association's Quality of Care and Outcomes...
Many breast cancer patients don't get treatment for heart problems
http://mnt.to/l/4nCf
Only a third of older breast cancer patients saw a cardiologist within 90 days of developing heart problems, in a study presented at the American Heart Association's Quality of Care and...
----------------------------------------------
** CHOLESTEROL News **
Patients with terminal illnesses benefit from stopping statins
http://mnt.to/l/4nGq
Cholesterol-lowering statins are widely used, but new research suggests patients in late stages of terminal illnesses may extend their lives by discontinuing use of the drug.
----------------------------------------------
** CLINICAL TRIALS / DRUG TRIALS News **
Immunotherapy trials reveal 'encouraging' results for melanoma treatment
http://mnt.to/l/4nGG
Two new studies reveal how the drugs nivolumab, ipilimumab and pembrolizumab improved overall survival for patients with advanced melanoma, showing promise for new treatments.
VELCADE Phase 3 study results presented for patients with mantle cell lymphoma
http://mnt.to/l/4nFq
Millennium: The Takeda Oncology Company has announced results from the primary analysis of an international, randomized Phase 3 study that showed treatment with a VELCADE®...
----------------------------------------------
** COLORECTAL CANCER News **
Promising response to new combination therapy by patients with metastatic colon cancer
http://mnt.to/l/4nDy
In an aggressive disease known for poor response rates, researchers from The University of Texas MD Anderson Cancer Center found patients with advanced colorectal cancer responded well to a...
----------------------------------------------
** CONFERENCES News **
4th Digital Marketing for Medical Devices, August 11-13, 2014, Minneapolis
http://mnt.to/l/4nG5
Digital marketing has opened the door to opportunities never before believed possible.
Target Meeting's 3rd World Neuroscience Online Conference, June 17-19, 2014: Join for Free
http://mnt.to/l/4nG3
A Free Virtual Neuroscience Conference at Targetmeeting.com featuring 50+ live presentations from academic and industry experts around the world.
----------------------------------------------
** COPD News **
Volatile organic compounds in exhaled breath show presence and stage of lung cancer
http://mnt.to/l/4nDD
Results of a University of Colorado Cancer Center study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) show that a test of organic compounds in exhaled...
----------------------------------------------
** DEPRESSION News **
Depression linked to early death among seniors with diabetes
http://mnt.to/l/4nDb
People with diabetes have about double the risk of premature death as people of the same age without diabetes.
Unexpected death of a loved one linked to onset of psychiatric disorders
http://mnt.to/l/4nCF
The sudden loss of a loved one can trigger a variety of psychiatric disorders in people with no history of mental illness, according to researchers at Columbia University's Mailman School of...
----------------------------------------------
** DERMATOLOGY News **
Study finds high risk of recurrence of two life-threatening adverse drug reactions that affect the skin - SJS and TEN
http://mnt.to/l/4nFd
Individuals who are hospitalized for the skin conditions of Stevens-Johnson syndrome and toxic epidermal necrolysis appear to have a high risk of recurrence, according to a study in JAMA.
----------------------------------------------
** DIABETES News **
Discovery of possible basis for treating circadian clock disorders and associated metabolic problems
http://mnt.to/l/4nDJ
Structural biologists have made important progress towards better understanding the functioning of the circadian clock.
Depression linked to early death among seniors with diabetes
http://mnt.to/l/4nDb
People with diabetes have about double the risk of premature death as people of the same age without diabetes.
More than 10 percent of heart attack patients may have undiagnosed diabetes
http://mnt.to/l/4nCh
At least 10 percent of people who have a heart attack may have undiagnosed diabetes, according to new research presented at the American Heart Association's Quality of Care and Outcomes...
----------------------------------------------
** EATING DISORDERS News **
The appeal of well-being applications often short-lived: Finnish study
http://mnt.to/l/4nD3
According to a doctoral thesis by Research Scientist Kirsikka Kaipainen from VTT Technical Research Centre of Finland, online and mobile applications for stress management and healthy eating...
----------------------------------------------
** ENDOCRINOLOGY News **
New treatment option for young women with hormone-sensitive breast cancer
http://mnt.to/l/4nFk
The aromatase inhibitor exemestane is more effective than tamoxifen in preventing breast cancer recurrence in young women who also receive ovarian function suppression as adjuvant...
----------------------------------------------
** EPILEPSY News **
Psychiatric comorbidities are common in people with epilepsy, but underestimated and often untreated
http://mnt.to/l/4nFx
"Up to 60 percent of people with epilepsy suffer from psychiatric comorbidities such as anxiety or depression, but the situation is still not getting the attention it deserves.
----------------------------------------------
** FERTILITY News **
Quicker, cheaper, and accurate embryo screening offered by new genetic sequencing methods
http://mnt.to/l/4nD4
Results from the first study of the clinical application of next generation DNA sequencing (NGS) in screening embryos for genetic disease prior to implantation in patients undergoing in-vitro...
----------------------------------------------
** GASTROINTESTINAL / GASTROENTEROLOGY News **
Combing family genomes using powerful new tool to identify disease-causing variations
http://mnt.to/l/4nCH
Scientists at the University of Utah (U of U), the University of Texas MD Anderson Cancer Center in Houston and colleagues have developed a powerful tool called pVAAST that combines linkage...
----------------------------------------------
** GENETICS News **
Study finds risk of recurrence low in smallest HER2+ breast cancer tumors
http://mnt.to/l/4nFh
Patients with specific HER2+ breast cancer tumors had a low risk of the cancer recurring five years after diagnosis, even without chemotherapy or treatment with a common antibody, according to...
Promising response to new combination therapy by patients with metastatic colon cancer
http://mnt.to/l/4nDy
In an aggressive disease known for poor response rates, researchers from The University of Texas MD Anderson Cancer Center found patients with advanced colorectal cancer responded well to a...
Saliva and common body proteins contain compounds that may fend off DNA-damaging chemicals
http://mnt.to/l/4nDg
A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study...
Bladder cancer patients carrying three specific mutations benefit from early chemotherapy
http://mnt.to/l/4nDc
Three genetic changes can predict whether a patient will benefit from chemotherapy before surgery to remove bladder cancer, according to new findings presented by Fox Chase Cancer Center...
Quicker, cheaper, and accurate embryo screening offered by new genetic sequencing methods
http://mnt.to/l/4nD4
Results from the first study of the clinical application of next generation DNA sequencing (NGS) in screening embryos for genetic disease prior to implantation in patients undergoing in-vitro...
Identification of mechanisms of ibrutinib resistance in chronic lymphocytic leukemia
http://mnt.to/l/4nCJ
A new study has discovered how resistance develops in patients taking ibrutinib, a new and highly effective drug for the treatment of chronic lymphocytic leukemia (CLL).
Combing family genomes using powerful new tool to identify disease-causing variations
http://mnt.to/l/4nCH
Scientists at the University of Utah (U of U), the University of Texas MD Anderson Cancer Center in Houston and colleagues have developed a powerful tool called pVAAST that combines linkage...
----------------------------------------------
** HEART DISEASE News **
Preventive placement of ICDs in patients with less severe heart failure associated with improved survival
http://mnt.to/l/4nF8
An examination of the benefit of preventive placement of implantable cardioverter-defibrillators (ICDs) in patients with a less severe level of heart failure, a group not well represented in...
'Off-pump' heart bypass surgery may reduce risk of postoperative kidney injury, although no improvement in long-term function
http://mnt.to/l/4nF6
Among patients undergoing coronary artery bypass graft (CABG) surgery, those who were not put on a heart-lung machine (off-pump) had a reduced risk of postoperative kidney injury compared to...
More than 10 percent of heart attack patients may have undiagnosed diabetes
http://mnt.to/l/4nCh
At least 10 percent of people who have a heart attack may have undiagnosed diabetes, according to new research presented at the American Heart Association's Quality of Care and Outcomes...
----------------------------------------------
** HIV / AIDS News **
For HIV+ patients diagnosed with lymphoma, hepatitis C reactivation does not worsen survival outcomes
http://mnt.to/l/4nDf
More than a quarter of HIV+ patients are also infected with the Hepatitis C virus (HCV), which may complicate treatment and care decisions after a cancer diagnosis.
For patients with AIDS-related lymphomas, identification of central nervous system involvement at diagnosis does not affect overall survival
http://mnt.to/l/4nDd
Patients with AIDS-related lymphomas (ARL) may face an increased risk of central nervous system involvement (CNSi) compared to other lymphomas.
----------------------------------------------
** HYPERTENSION News **
Discovery of possible basis for treating circadian clock disorders and associated metabolic problems
http://mnt.to/l/4nDJ
Structural biologists have made important progress towards better understanding the functioning of the circadian clock.
Community program helps lower blood pressure among minorities
http://mnt.to/l/4nCS
Minorities at a higher risk of developing hypertension used a community-based program to significantly lower their blood pressure, researchers said at the American Heart Association's Quality...
----------------------------------------------
** IMMUNE SYSTEM / VACCINES News **
Immunotherapy trials reveal 'encouraging' results for melanoma treatment
http://mnt.to/l/4nGG
Two new studies reveal how the drugs nivolumab, ipilimumab and pembrolizumab improved overall survival for patients with advanced melanoma, showing promise for new treatments.
Rejection risk cut by coaxing iPS cells to become more specialized prior to transplantation
http://mnt.to/l/4nDH
For many scientists, the clinical promise of stem cells has been dampened by very real concerns that the immune system will reject the transplanted cells before they could render any long-term...
Advanced bladder cancer patients benefit from immune therapy
http://mnt.to/l/4nDv
A multi-center phase I study using an investigational drug for advanced bladder cancer patients who did not respond to other treatments has shown promising results in patients with certain tumor...
10-valent pneumococcal conjugate vaccine is effective for preventing community-acquired pneumonia in infants in Latin America
http://mnt.to/l/4nzP
A 10-valent pneumococcal conjugate vaccine (PCV) is effective in reducing the number of new cases of likely-bacterial community-acquired pneumonia in infants in Latin America, according to a...
----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Scientists discover how deadly ebola virus 'punches' its way into human cells
http://mnt.to/l/4nFy
At first, cells contain the ebola virus in a vesicle awaiting disposal, but the pH level of the vesicle triggers the virus to make a molecular fist and it punches its way out.
Measles cases in the United States reach 20-year high
http://mnt.to/l/4nF5
Two hundred and eighty-eight cases of measles were reported to the Centers for Disease Control and Prevention (CDC) in the United States between Jan. 1 and May 23, 2014.
Hydrogels - special substances that can be equipped to detect bacteria, carry cargo and deliver medicine
http://mnt.to/l/4nDG
Next time you spot an earthworm sliding through fresh dirt, take a closer look.
----------------------------------------------
** LIVER DISEASE / HEPATITIS News **
Targeting cancer stem cells: results in phase I trial of OMP-54F28
http://mnt.to/l/4nDw
At the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO), University of Colorado Cancer Center researchers reported results of a Phase I trial of OMP-54F28 (FZD8-Fc), an...
For HIV+ patients diagnosed with lymphoma, hepatitis C reactivation does not worsen survival outcomes
http://mnt.to/l/4nDf
More than a quarter of HIV+ patients are also infected with the Hepatitis C virus (HCV), which may complicate treatment and care decisions after a cancer diagnosis.
----------------------------------------------
** LUNG CANCER News **
Volatile organic compounds in exhaled breath show presence and stage of lung cancer
http://mnt.to/l/4nDD
Results of a University of Colorado Cancer Center study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) show that a test of organic compounds in exhaled...
New targetable form of disease revealed by responses with crizotinib in MET-amplified lung cancer
http://mnt.to/l/4nDx
A study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2014 reports the results of a first-in-human, phase 1 dose escalation trial of crizotinib (XALKORI) in 14...
----------------------------------------------
** LYMPHOLOGY/LYMPHEDEMA News **
For patients with AIDS-related lymphomas, identification of central nervous system involvement at diagnosis does not affect overall survival
http://mnt.to/l/4nDd
Patients with AIDS-related lymphomas (ARL) may face an increased risk of central nervous system involvement (CNSi) compared to other lymphomas.
----------------------------------------------
** LYMPHOMA / LEUKEMIA / MYELOMA News **
VELCADE Phase 3 study results presented for patients with mantle cell lymphoma
http://mnt.to/l/4nFq
Millennium: The Takeda Oncology Company has announced results from the primary analysis of an international, randomized Phase 3 study that showed treatment with a VELCADE®...
Support of ibrutinib strengthened as second-line therapy for CLL by phase 3 study
http://mnt.to/l/4nDz
In a head-to-head comparison of two Food and Drug Administration-approved drugs for the treatment of relapsed chronic lymphocytic leukemia (CLL), ibrutinib significantly outperformed ofatumumab...
New targetable form of disease revealed by responses with crizotinib in MET-amplified lung cancer
http://mnt.to/l/4nDx
A study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting 2014 reports the results of a first-in-human, phase 1 dose escalation trial of crizotinib (XALKORI) in 14...
For HIV+ patients diagnosed with lymphoma, hepatitis C reactivation does not worsen survival outcomes
http://mnt.to/l/4nDf
More than a quarter of HIV+ patients are also infected with the Hepatitis C virus (HCV), which may complicate treatment and care decisions after a cancer diagnosis.
The loss of a cell protein favors cancer cells while harming healthy cells
http://mnt.to/l/4nCZ
Janus kinases (JAKs) are proteins that can promote the growth of cancer cells. The protein JAK2 is of special therapeutic significance: its inactivation is believed to destroy cancer cells.
Identification of mechanisms of ibrutinib resistance in chronic lymphocytic leukemia
http://mnt.to/l/4nCJ
A new study has discovered how resistance develops in patients taking ibrutinib, a new and highly effective drug for the treatment of chronic lymphocytic leukemia (CLL).
----------------------------------------------
** MEDICAL DEVICES / DIAGNOSTICS News **
Preventive placement of ICDs in patients with less severe heart failure associated with improved survival
http://mnt.to/l/4nF8
An examination of the benefit of preventive placement of implantable cardioverter-defibrillators (ICDs) in patients with a less severe level of heart failure, a group not well represented in...
3D printing successfully used to address the ongoing challenge of making artificial blood vessels
http://mnt.to/l/4nDF
The tangled highway of blood vessels that twists and turns inside our bodies, delivering essential nutrients and disposing of hazardous waste to keep our organs working properly has been a...
Volatile organic compounds in exhaled breath show presence and stage of lung cancer
http://mnt.to/l/4nDD
Results of a University of Colorado Cancer Center study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) show that a test of organic compounds in exhaled...
----------------------------------------------
** MELANOMA / SKIN CANCER News **
Immunotherapy trials reveal 'encouraging' results for melanoma treatment
http://mnt.to/l/4nGG
Two new studies reveal how the drugs nivolumab, ipilimumab and pembrolizumab improved overall survival for patients with advanced melanoma, showing promise for new treatments.
----------------------------------------------
** MENOPAUSE News **
Non-Western experiences discounted in standard approaches to menopause symptoms
http://mnt.to/l/4nDn
Dr Mwenza T. Blell of the University of Bristol interviewed 257 British Pakistani women aged 39-61 living in West Yorkshire and found that the standard checklist approach to studying menopause...
A major step towards better diagnosis and treatment of osteoporosis
http://mnt.to/l/4nD5
A new target that may be critical for the treatment of osteoporosis, a disease which affects about 25% of post-menopausal women, has been discovered by a group of researchers in The Netherlands...
----------------------------------------------
** MENTAL HEALTH News **
Antipsychotic medication taken during pregnancy does affect babies, study shows
http://mnt.to/l/4nFr
A seven-year study of women who take antipsychotic medication while pregnant, proves it can affect babies.
Study finds that suicides are far more likely to occur after midnight
http://mnt.to/l/4nFn
A new study provides novel evidence suggesting that suicides are far more likely to occur between midnight and 4 a.m. than during the daytime or evening.
Study suggests 1 in 8 American children maltreated before age 18
http://mnt.to/l/4nFg
A new study in JAMA Pediatrics attempts to solve some of the problems in calculating prevalence of maltreatment among children in the US.
----------------------------------------------
** NEUROLOGY / NEUROSCIENCE News **
For patients with AIDS-related lymphomas, identification of central nervous system involvement at diagnosis does not affect overall survival
http://mnt.to/l/4nDd
Patients with AIDS-related lymphomas (ARL) may face an increased risk of central nervous system involvement (CNSi) compared to other lymphomas.
----------------------------------------------
** NUTRITION / DIET News **
Weight loss aided by eating prunes
http://mnt.to/l/4nDr
Research by the University of Liverpool has found that eating prunes as part of a weight control diet can improve weight loss.
Saliva and common body proteins contain compounds that may fend off DNA-damaging chemicals
http://mnt.to/l/4nDg
A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study...
Giving children a taste for vegetables 'often and early'
http://mnt.to/l/4nD6
Exposing infants to a new vegetable early in life encourages them to eat more of it compared to offering novel vegetables to older children, new research from the University of Leeds suggests.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
No sign of 'obesity paradox' in obese patients with stroke
http://mnt.to/l/4nFs
Researchers found no evidence of an "obesity paradox" (some studies have suggested overweight or obese patients have lower mortality rates than underweight or normal weight patients) in...
Weight loss aided by eating prunes
http://mnt.to/l/4nDr
Research by the University of Liverpool has found that eating prunes as part of a weight control diet can improve weight loss.
----------------------------------------------
** OVARIAN CANCER News **
Targeting cancer stem cells: results in phase I trial of OMP-54F28
http://mnt.to/l/4nDw
At the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO), University of Colorado Cancer Center researchers reported results of a Phase I trial of OMP-54F28 (FZD8-Fc), an...
More patients with ovarian cancer are receiving chemotherapy before surgery
http://mnt.to/l/4nDh
The use of chemotherapy before surgery to remove ovarian cancer has increased dramatically in recent decades, particularly among certain patients, according to a new analysis from Fox Chase...
In patients with pancreatic or ovarian cancer, phase I study of DMOT4039A
http://mnt.to/l/4nD7
A study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) describes the results of a phase I clinical trial of the investigational agent DMOT4039A against...
----------------------------------------------
** PALLIATIVE CARE / HOSPICE CARE News **
Place and cause of death in centenarians: a population-based observational study in England, 2001 to 2010
http://mnt.to/l/4nzM
Centenarians are more likely to die of pneumonia and frailty or "old age" and less likely to die of the chronic conditions often associated with old age, such as cancer or ischemic heart...
----------------------------------------------
** PANCREATIC CANCER News **
Targeting cancer stem cells: results in phase I trial of OMP-54F28
http://mnt.to/l/4nDw
At the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO), University of Colorado Cancer Center researchers reported results of a Phase I trial of OMP-54F28 (FZD8-Fc), an...
In patients with pancreatic or ovarian cancer, phase I study of DMOT4039A
http://mnt.to/l/4nD7
A study presented at the 50th Annual Meeting of the American Society for Clinical Oncology (ASCO) describes the results of a phase I clinical trial of the investigational agent DMOT4039A against...
----------------------------------------------
** PEDIATRICS / CHILDREN'S HEALTH News **
Study suggests 1 in 8 American children maltreated before age 18
http://mnt.to/l/4nFg
A new study in JAMA Pediatrics attempts to solve some of the problems in calculating prevalence of maltreatment among children in the US.
Study identifies factors that may 'predict smoking cessation in teens'
http://mnt.to/l/4nFb
Researchers from Canada say they have identified a number of factors that could be used to predict the likelihood of smoking cessation in adolescents who are new to the habit.
Measles cases in the United States reach 20-year high
http://mnt.to/l/4nF5
Two hundred and eighty-eight cases of measles were reported to the Centers for Disease Control and Prevention (CDC) in the United States between Jan. 1 and May 23, 2014.
Giving children a taste for vegetables 'often and early'
http://mnt.to/l/4nD6
Exposing infants to a new vegetable early in life encourages them to eat more of it compared to offering novel vegetables to older children, new research from the University of Leeds suggests.
Combing family genomes using powerful new tool to identify disease-causing variations
http://mnt.to/l/4nCH
Scientists at the University of Utah (U of U), the University of Texas MD Anderson Cancer Center in Houston and colleagues have developed a powerful tool called pVAAST that combines linkage...
10-valent pneumococcal conjugate vaccine is effective for preventing community-acquired pneumonia in infants in Latin America
http://mnt.to/l/4nzP
A 10-valent pneumococcal conjugate vaccine (PCV) is effective in reducing the number of new cases of likely-bacterial community-acquired pneumonia in infants in Latin America, according to a...
----------------------------------------------
** PHARMA INDUSTRY / BIOTECH INDUSTRY News **
Hydrogels - special substances that can be equipped to detect bacteria, carry cargo and deliver medicine
http://mnt.to/l/4nDG
Next time you spot an earthworm sliding through fresh dirt, take a closer look.
----------------------------------------------
** PHARMACY / PHARMACIST News **
Study finds high risk of recurrence of two life-threatening adverse drug reactions that affect the skin - SJS and TEN
http://mnt.to/l/4nFd
Individuals who are hospitalized for the skin conditions of Stevens-Johnson syndrome and toxic epidermal necrolysis appear to have a high risk of recurrence, according to a study in JAMA.
----------------------------------------------
** PREGNANCY / OBSTETRICS News **
Antipsychotic medication taken during pregnancy does affect babies, study shows
http://mnt.to/l/4nFr
A seven-year study of women who take antipsychotic medication while pregnant, proves it can affect babies.
----------------------------------------------
** PRIMARY CARE / GENERAL PRACTICE News **
Study finds high risk of recurrence of two life-threatening adverse drug reactions that affect the skin - SJS and TEN
http://mnt.to/l/4nFd
Individuals who are hospitalized for the skin conditions of Stevens-Johnson syndrome and toxic epidermal necrolysis appear to have a high risk of recurrence, according to a study in JAMA.
Study identifies factors that may 'predict smoking cessation in teens'
http://mnt.to/l/4nFb
Researchers from Canada say they have identified a number of factors that could be used to predict the likelihood of smoking cessation in adolescents who are new to the habit.
Community program helps lower blood pressure among minorities
http://mnt.to/l/4nCS
Minorities at a higher risk of developing hypertension used a community-based program to significantly lower their blood pressure, researchers said at the American Heart Association's Quality...
----------------------------------------------
** PROSTATE / PROSTATE CANCER News **
Risk of secondary cancers increased following radiation for prostate cancer
http://mnt.to/l/4nDq
Among men treated for prostate cancer, those who received radiation therapy were more likely to develop bladder or rectal cancer, according to a new study from the University of Michigan...
----------------------------------------------
** PSYCHOLOGY / PSYCHIATRY News **
Psychiatric comorbidities are common in people with epilepsy, but underestimated and often untreated
http://mnt.to/l/4nFx
"Up to 60 percent of people with epilepsy suffer from psychiatric comorbidities such as anxiety or depression, but the situation is still not getting the attention it deserves.
Study suggests 1 in 8 American children maltreated before age 18
http://mnt.to/l/4nFg
A new study in JAMA Pediatrics attempts to solve some of the problems in calculating prevalence of maltreatment among children in the US.
New clinical guidelines for cancer-related fatigue
http://mnt.to/l/4nDp
Fatigue is a debilitating problem for cancer patients undergoing treatment; however, it also poses a huge detriment after treatment and can significantly affect quality of life.
The appeal of well-being applications often short-lived: Finnish study
http://mnt.to/l/4nD3
According to a doctoral thesis by Research Scientist Kirsikka Kaipainen from VTT Technical Research Centre of Finland, online and mobile applications for stress management and healthy eating...
Unexpected death of a loved one linked to onset of psychiatric disorders
http://mnt.to/l/4nCF
The sudden loss of a loved one can trigger a variety of psychiatric disorders in people with no history of mental illness, according to researchers at Columbia University's Mailman School of...
----------------------------------------------
** PUBLIC HEALTH News **
Does marijuana use cause sleep problems?
http://mnt.to/l/4nFw
New research due to be presented at SLEEP 2014 finds an association between marijuana use and impaired sleep, but it cannot determine causality.
New virtual platform measures the level of addiction to tobacco
http://mnt.to/l/4nFt
In Mexico, 21.7 percent of the population smokes, which is associated with 95 percent of 
lung cancer cases and the development of 29 more different conditions.
Measles cases in the United States reach 20-year high
http://mnt.to/l/4nF5
Two hundred and eighty-eight cases of measles were reported to the Centers for Disease Control and Prevention (CDC) in the United States between Jan. 1 and May 23, 2014.
Evidence for dangers of repellent DEET in question
http://mnt.to/l/4nDW
The benefits of avoiding disease-spreading insect bites outweighs the potential risks of using DEET, according to a review of the evidence in the open access journal Parasites and Vectors.
Mortality risk greatest following surgery in afternoons, at weekends, and in February
http://mnt.to/l/4nDC
New research presented at this year's Euroanaesthesia show that on weekends, in the afternoons and in February are the times when the risk of death following surgery is the highest.
Further evidence that patients admitted to hospital at weekends have higher mortality: study of 55 million people
http://mnt.to/l/4nDB
A systematic review and meta-analysis of hospital data worldwide, presented as this year's Euroanaesthesia meeting in Stockholm, adds further evidence that patients admitted to hospital at...
It is estimated that there will be nearly 19 million cancer survivors in the U.S by 2024
http://mnt.to/l/4nDt
The number of cancer survivors in the United States, currently estimated to be 14.5 million, will grow to almost 19 million by 2024, according to an updated report by the American Cancer Society.
Urban development could be a factor in the number of lives lost due to heat in future summers
http://mnt.to/l/4nDm
Phoenix stands at a parched crossroads. Global scale climate change is forecast to bring hotter summers and more extreme heat to the Valley, but regional urbanization also will impact...
----------------------------------------------
** RADIOLOGY / NUCLEAR MEDICINE News **
Risk of secondary cancers increased following radiation for prostate cancer
http://mnt.to/l/4nDq
Among men treated for prostate cancer, those who received radiation therapy were more likely to develop bladder or rectal cancer, according to a new study from the University of Michigan...
----------------------------------------------
** REGULATORY AFFAIRS / DRUG APPROVALS News **
FDA approves first generic versions of celecoxib
http://mnt.to/l/4nFj
The U.S. Food and Drug Administration has approved the first generic versions of Celebrex (celecoxib) capsules, a treatment for rheumatoid arthritis, osteoarthritis, short-term (acute) pain...
----------------------------------------------
** RESPIRATORY / ASTHMA News **
For older adults with pneumonia, treatment including azithromycin associated with lower risk of death, small increased risk of heart attack
http://mnt.to/l/4nF9
In a study that included nearly 65,000 older patients hospitalized with pneumonia, treatment that included azithromycin compared with other antibiotics was associated with a significantly...
10-valent pneumococcal conjugate vaccine is effective for preventing community-acquired pneumonia in infants in Latin America
http://mnt.to/l/4nzP
A 10-valent pneumococcal conjugate vaccine (PCV) is effective in reducing the number of new cases of likely-bacterial community-acquired pneumonia in infants in Latin America, according to a...
----------------------------------------------
** SENIORS / AGING News **
Depression linked to early death among seniors with diabetes
http://mnt.to/l/4nDb
People with diabetes have about double the risk of premature death as people of the same age without diabetes.
Place and cause of death in centenarians: a population-based observational study in England, 2001 to 2010
http://mnt.to/l/4nzM
Centenarians are more likely to die of pneumonia and frailty or "old age" and less likely to die of the chronic conditions often associated with old age, such as cancer or ischemic heart...
----------------------------------------------
** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Does marijuana use cause sleep problems?
http://mnt.to/l/4nFw
New research due to be presented at SLEEP 2014 finds an association between marijuana use and impaired sleep, but it cannot determine causality.
Discovery of possible basis for treating circadian clock disorders and associated metabolic problems
http://mnt.to/l/4nDJ
Structural biologists have made important progress towards better understanding the functioning of the circadian clock.
----------------------------------------------
** SMOKING / QUIT SMOKING News **
New virtual platform measures the level of addiction to tobacco
http://mnt.to/l/4nFt
In Mexico, 21.7 percent of the population smokes, which is associated with 95 percent of 
lung cancer cases and the development of 29 more different conditions.
Huge rise in e-cigarette TV advertising for young adults
http://mnt.to/l/4nFm
The first study of its kind reveals the extent to which young adults and young people are exposed to electronic cigarette television advertisements.
Study identifies factors that may 'predict smoking cessation in teens'
http://mnt.to/l/4nFb
Researchers from Canada say they have identified a number of factors that could be used to predict the likelihood of smoking cessation in adolescents who are new to the habit.
Elevated levels of carbon monoxide and air nicotine found in baltimore hookah bars
http://mnt.to/l/4nCC
Smoking waterpipes, or hookahs, creates hazardous concentrations of indoor air pollution and poses increased risk from diminished air quality for both employees and patrons of waterpipe bars...
----------------------------------------------
** STATINS News **
Patients with terminal illnesses benefit from stopping statins
http://mnt.to/l/4nGq
Cholesterol-lowering statins are widely used, but new research suggests patients in late stages of terminal illnesses may extend their lives by discontinuing use of the drug.
----------------------------------------------
** STEM CELL RESEARCH News **
Rejection risk cut by coaxing iPS cells to become more specialized prior to transplantation
http://mnt.to/l/4nDH
For many scientists, the clinical promise of stem cells has been dampened by very real concerns that the immune system will reject the transplanted cells before they could render any long-term...
The loss of a cell protein favors cancer cells while harming healthy cells
http://mnt.to/l/4nCZ
Janus kinases (JAKs) are proteins that can promote the growth of cancer cells. The protein JAK2 is of special therapeutic significance: its inactivation is believed to destroy cancer cells.
----------------------------------------------
** STROKE News **
No sign of 'obesity paradox' in obese patients with stroke
http://mnt.to/l/4nFs
Researchers found no evidence of an "obesity paradox" (some studies have suggested overweight or obese patients have lower mortality rates than underweight or normal weight patients) in...
----------------------------------------------
** TRANSPLANTS / ORGAN DONATIONS News **
Rejection risk cut by coaxing iPS cells to become more specialized prior to transplantation
http://mnt.to/l/4nDH
For many scientists, the clinical promise of stem cells has been dampened by very real concerns that the immune system will reject the transplanted cells before they could render any long-term...
----------------------------------------------
** TROPICAL DISEASES News **
Scientists discover how deadly ebola virus 'punches' its way into human cells
http://mnt.to/l/4nFy
At first, cells contain the ebola virus in a vesicle awaiting disposal, but the pH level of the vesicle triggers the virus to make a molecular fist and it punches its way out.
Evidence for dangers of repellent DEET in question
http://mnt.to/l/4nDW
The benefits of avoiding disease-spreading insect bites outweighs the potential risks of using DEET, according to a review of the evidence in the open access journal Parasites and Vectors.
----------------------------------------------
** UROLOGY / NEPHROLOGY News **
European ADPKD forum (EAF) launches: expert group to improve the management of autosomal dominant polycystic kidney disease throughout Europe
http://mnt.to/l/4nFf
31st May 2014 marked the formation of the European ADPKD Forum (EAF), a new multidisciplinary group of leading medical and patient group experts dedicated to improving the health and quality...
Findings show benefit of changing measure of kidney disease progression
http://mnt.to/l/4nF7
Developing therapies for kidney disease can be made faster by adopting a new, more sensitive definition of kidney disease progression, according to a study published by JAMA.
Reduced kidney function associated with higher risk of renal and urothelial cancer
http://mnt.to/l/4nF4
A key measure of reduced kidney function and chronic kidney disease - reduced glomerular filtration rate - is an independent risk factor for renal and urothelial cancer, according to a study...
Advanced bladder cancer patients benefit from immune therapy
http://mnt.to/l/4nDv
A multi-center phase I study using an investigational drug for advanced bladder cancer patients who did not respond to other treatments has shown promising results in patients with certain tumor...
Potential dangers of chemotherapy regimen for bladder cancer patients uncovered by trial
http://mnt.to/l/4nDs
Patients with muscle-invasive bladder cancer often benefit from chemotherapy before surgery to remove the tumor, but a test of one regimen by researchers at Fox Chase Cancer Center was halted...
Bladder cancer patients carrying three specific mutations benefit from early chemotherapy
http://mnt.to/l/4nDc
Three genetic changes can predict whether a patient will benefit from chemotherapy before surgery to remove bladder cancer, according to new findings presented by Fox Chase Cancer Center...
----------------------------------------------
** VASCULAR News **
3D printing successfully used to address the ongoing challenge of making artificial blood vessels
http://mnt.to/l/4nDF
The tangled highway of blood vessels that twists and turns inside our bodies, delivering essential nutrients and disposing of hazardous waste to keep our organs working properly has been a...
----------------------------------------------
** WATER - AIR QUALITY / AGRICULTURE News **
Elevated levels of carbon monoxide and air nicotine found in baltimore hookah bars
http://mnt.to/l/4nCC
Smoking waterpipes, or hookahs, creates hazardous concentrations of indoor air pollution and poses increased risk from diminished air quality for both employees and patrons of waterpipe bars...
----------------------------------------------
** WOMEN'S HEALTH / GYNECOLOGY News **
Quicker, cheaper, and accurate embryo screening offered by new genetic sequencing methods
http://mnt.to/l/4nD4
Results from the first study of the clinical application of next generation DNA sequencing (NGS) in screening embryos for genetic disease prior to implantation in patients undergoing in-vitro...
-------------------------------------------------------------
You are receiving this newsletter because you subscribed through a form on our web site, Medical News Today (http://www.medicalnewstoday.com). If you wish to alter any of your subscription details (name, email address etc) or chosen news categories, please sign up for a free MNT account here:
http://mnt.to/newslet?kostikblog%40ukr.net&k=6fd75cd6039cd89d3652154922b0df34
To unsubscribe without signing up, please click http://mnt.to/unsubscr?kostikblog%40ukr.net&k=6fd75cd6039cd89d3652154922b0df34
