Medical News Today daily newsletter - 30 June 2014

Dear kostik,

Welcome to today's Medical News Today newsletter, containing the most recent headlines from your chosen news categories.

----------------------------------------------
** ADHD News **

Published data shows long-term efficacy of Elvanse® (lisdexamfetamine dimesylate) in children and adolescents with ADHD
http://mnt.to/l/4pb2
A new paper published in the Journal of the American Association of Children and Adolescent Psychiatry (JAACAP) shows long-term efficacy of lisdexamfetamine dimesylate (LDX) in children and...

Psychostimulants and cardiovascular risk in children with ADHD
http://mnt.to/l/4p9k
Psychostimulant use to treat children and adolescents with attention-deficit/hyperactivity disorder (ADHD) is increasing worldwide, and the evaluation of the cardiovascular safety of stimulant...

----------------------------------------------
** AID / DISASTERS News **

In Afghanistan, real health gains from foreign aid
http://mnt.to/l/4pbh
More than a decade after the American invasion, Afghanistan remains at war. Corruption is endemic, drug production is at historic levels, armed militias and other groups are positioning for...

----------------------------------------------
** ALCOHOL / ADDICTION / ILLEGAL DRUGS News **

Effectiveness of addiction drugs 'depends on phase of addiction'
http://mnt.to/l/4pck
In a model of rats trained to self-administer cocaine, researchers found that efficacy of treatments to control drug-seeking behavior depended on the subject's phase of addiction.

A study shows that child maltreatment influences alcohol consumption in adolescents
http://mnt.to/l/4pb9
A study coordinated by Jorge Manzanares, Professor of Pharmacology at the University Miguel Hernández (UMH) in Elche (Spain), shows that child maltreatment, whatever its form, produces...

----------------------------------------------
** ALLERGY News **

Caregivers' allergy perceptions not always accurate
http://mnt.to/l/4p8R
It's tough being the parent of a child with food allergies. Constant vigilance is needed for everything your child eats, when a single food item containing a hidden ingredient can be fatal.

----------------------------------------------
** ANXIETY / STRESS News **

Brain circuits identified that are involved in stress-induced fevers
http://mnt.to/l/4p95
When we feel mentally stressed, we often also feel physiological changes, including a faster heart rate and an increase in body temperature.

----------------------------------------------
** ARTHRITIS / RHEUMATOLOGY News **

One third of total knee replacements in US are 'inappropriate'
http://mnt.to/l/4pbj
A new study examines Spanish appropriateness criteria for total knee replacement surgery, in response to concerns that the surgery has become overused in the US.

----------------------------------------------
** AUTISM News **

Autism and driving: first study asks autistic adults about real-world driving experiences
http://mnt.to/l/4p9z
In the first pilot study asking adults on the autism spectrum about their experiences with driving, researchers at Drexel University found significant differences in self-reported driving...

----------------------------------------------
** BIOLOGY / BIOCHEMISTRY News **

Scientists map cell's DNA history to embryonic origin
http://mnt.to/l/4pbY
By looking at mutations in a cell's DNA, scientists can work out how the cell has changed since its genetic origin in the fertilized egg. This could be useful for cancer research.

PolySciTech's SpinSwiper could speed the production of controlled-release microparticles
http://mnt.to/l/4pb3
Researchers in academic, commercial and pharmaceutical settings who need to generate microparticles, including those used in controlled-release drug delivery, could benefit from a new product...

Reconstructing the life history of a single cell - Cell's unique mutations used to trace history back to its origins in the embryo
http://mnt.to/l/4p9N
Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg.

----------------------------------------------
** BONES / ORTHOPEDICS News **

One third of total knee replacements in US are 'inappropriate'
http://mnt.to/l/4pbj
A new study examines Spanish appropriateness criteria for total knee replacement surgery, in response to concerns that the surgery has become overused in the US.

Potential new therapeutic target for osteoporosis: MicroRNA that blocks bone destruction
http://mnt.to/l/4p8V
UT Southwestern cancer researchers have identified a promising molecule that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone...

----------------------------------------------
** BREAST CANCER News **

Breast, prostate and colorectal cancer: 'family history bigger factor than lifestyle'
http://mnt.to/l/4pc7
Family history is a greater risk factor than lifestyle for developing some cancers, according to a Swedish study looking at 71,000 adopted people.

Simple blood test in development that could help predict the likelihood of a woman developing breast cancer
http://mnt.to/l/4p9g
A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation, according to...

Known breast cancer gene needs a partner to initiate and spread tumors
http://mnt.to/l/4p9c
A study led by Princeton University researchers has revealed that the gene Metadherin - which is implicated in promoting the spread of breast cancer tumors - only stimulates tumor growth when...

----------------------------------------------
** CANCER / ONCOLOGY News **

Breast, prostate and colorectal cancer: 'family history bigger factor than lifestyle'
http://mnt.to/l/4pc7
Family history is a greater risk factor than lifestyle for developing some cancers, according to a Swedish study looking at 71,000 adopted people.

Scientists map cell's DNA history to embryonic origin
http://mnt.to/l/4pbY
By looking at mutations in a cell's DNA, scientists can work out how the cell has changed since its genetic origin in the fertilized egg. This could be useful for cancer research.

Genetics dominant risk factor in common cancers
http://mnt.to/l/4pb7
A study of individuals who have been adopted has identified genetics as the dominant risk factor in 'familial' breast, prostate and colorectal cancers.

Invisibility cloak for immune cells
http://mnt.to/l/4p8X
The various cells in the immune system have to protect themselves from one another so that they don't kill each other.

Potential new therapeutic target for osteoporosis: MicroRNA that blocks bone destruction
http://mnt.to/l/4p8V
UT Southwestern cancer researchers have identified a promising molecule that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone...

----------------------------------------------
** CLINICAL TRIALS / DRUG TRIALS News **

Effectiveness of addiction drugs 'depends on phase of addiction'
http://mnt.to/l/4pck
In a model of rats trained to self-administer cocaine, researchers found that efficacy of treatments to control drug-seeking behavior depended on the subject's phase of addiction.

Published data shows long-term efficacy of Elvanse® (lisdexamfetamine dimesylate) in children and adolescents with ADHD
http://mnt.to/l/4pb2
A new paper published in the Journal of the American Association of Children and Adolescent Psychiatry (JAACAP) shows long-term efficacy of lisdexamfetamine dimesylate (LDX) in children and...

Multi-study analysis reinforces value of EXPAREL-based multimodal analgesia regimen
http://mnt.to/l/4p9X
Pacira Pharmaceuticals, Inc. has announced results from a pooled analysis of IMPROVE, a series of open-label prospective, Phase 4 clinical studies designed to compare postsurgical narcotic use...

Phase III trial shows improved survival with TAS-102 in metastatic colorectal cancer refractory to standard therapies
http://mnt.to/l/4p9L
The new combination agent TAS-102 is able to improve overall survival compared to placebo in patients whose metastatic colorectal cancer is refractory to standard therapies, researchers said...

----------------------------------------------
** COLORECTAL CANCER News **

Phase III trial shows improved survival with TAS-102 in metastatic colorectal cancer refractory to standard therapies
http://mnt.to/l/4p9L
The new combination agent TAS-102 is able to improve overall survival compared to placebo in patients whose metastatic colorectal cancer is refractory to standard therapies, researchers said...

----------------------------------------------
** CONFERENCES News **

Pharmaceutical Supplier Quality Assurance Conference, July 21-22, Arlington, Virginia
http://mnt.to/l/4pcf
By popular request, Q1 Productions will be hosting the inaugural Pharmaceutical Supplier Quality Assurance Conference July 21-22, in Arlington, Virginia, fulfilling the demand for a...

Medical Device Quality Management Systems Conference, September 11-12, Atlanta
http://mnt.to/l/4pcd
For the first time ever, a conference catered specifically to quality management systems professionals is available, filling a need for high-level, in-depth topics concerning all corners of...

Medical Device Strategic Pricing Conference, September 15-16, Atlanta
http://mnt.to/l/4pcc
Based on the overwhelming success of last year's inaugural Medical Device Strategic Pricing Conference, Q1 Productions will host the second annual event this September 15-16 in Atlanta...

2nd Annual Medical Device Product Development and Management Conference, September 18-19, Chicago
http://mnt.to/l/4pcb
For the second consecutive year, Q1 Productions will be hosting the Medical Device Product Development and Management Conference, offering attendees an opportunity to obtain the most recent...

Pharmaceutical Supply Chain Management Conference, October 9-10, 2014, New Orleans
http://mnt.to/l/4pc9
Serialization A Hot Topic At Upcoming Pharmaceutical Supply Chain Management ConferenceBy popular request, the Pharmaceutical Supply Chain Management Conference is back with the biggest...

5th Annual Clinical Affairs and Regulatory Approvals for Diagnostics Conference, October 27-29, Arlington, Virginia
http://mnt.to/l/4pc5
New Speakers, Additional Learning Opportunities Available at the 5th Annual Clinical Affairs and Regulatory Approvals for Diagnostics ConferenceThe most popular meeting for clinical and...

----------------------------------------------
** DENTISTRY News **

Impact of sugar on tooth decay remains a major health concern, says FGDP(UK)
http://mnt.to/l/4pb4
It is important that the effect of sugar intake on tooth decay is considered alongside obesity, type 2 diabetes and heart disease as a major public health challenge, according to the Faculty...

Vascular health in indigenous Australians improved by treating gum disease
http://mnt.to/l/4p9b
A simple non-surgical gum disease treatment markedly reduces the thickness of the wall of the arteries, a risk factor for heart disease, according to a first of its kind study among Aboriginal...

----------------------------------------------
** DEPRESSION News **

Traditional approaches in managing ABI-associated behavior challenged
http://mnt.to/l/4p8N
Individuals with brain injury and their families often struggle to accept the associated personality changes.

----------------------------------------------
** DIABETES News **

Obesity, high blood pressure, high triglycerides, and diabetes increase future risk for chronic kidney disease
http://mnt.to/l/4p97
Risk factors for chronic kidney disease (CKD) are present and identifiable 30 years before diagnosis, according to a study appearing in an upcoming issue of the Journal of the American Society...

Pre-pregnancy obesity associated with earliest preterm births
http://mnt.to/l/4p8S
Women who are obese before they become pregnant face an increased risk of delivering a very premature baby, according to a new study of nearly 1 million California births.

----------------------------------------------
** EPILEPSY News **

Structure, protein elements revealed that are critical to human function and disease
http://mnt.to/l/4p8Q
New structures discovered within cilia show a relationship between certain proteins and juvenile myoclonic epilepsy.

----------------------------------------------
** EYE HEALTH / BLINDNESS News **

New resource to help more blind young people into work backed by UK Ministers
http://mnt.to/l/4pbb
The Royal London Society for Blind People, a leading charity for blind and partially sighted young people has launched a dual purpose resource pack.

----------------------------------------------
** FERTILITY News **

Fertility treatment outcomes 'dependent on sperm quality, not age of donor'
http://mnt.to/l/4pbd
Many sperm banks do not accept donations from older men. But new research suggests outcomes of fertility treatment are dependent on sperm quality rather than the age of the donor.

----------------------------------------------
** GASTROINTESTINAL / GASTROENTEROLOGY News **

Coeliac UK launches new app to help manage a gluten-free diet
http://mnt.to/l/4p9Z
Coeliac UK, the national charity for people with coeliac disease, announces the launch of its new app called 'Gluten-free on the Move'.

Salmonella's favorite food could prove to be its undoing
http://mnt.to/l/4p9H
Study suggests that Salmonella’s reliance on one particular nutrient to survive, grow and inflict damage could lead to new treatment for the infection.

Interferons and viral infections
http://mnt.to/l/4p9y
Respiratory and intestinal infections caused by RNA viruses stimulate infected cells to produce interferons, which can act alone or in combination to block virus replication.

----------------------------------------------
** GENETICS News **

Scientists map cell's DNA history to embryonic origin
http://mnt.to/l/4pbY
By looking at mutations in a cell's DNA, scientists can work out how the cell has changed since its genetic origin in the fertilized egg. This could be useful for cancer research.

Genetics dominant risk factor in common cancers
http://mnt.to/l/4pb7
A study of individuals who have been adopted has identified genetics as the dominant risk factor in 'familial' breast, prostate and colorectal cancers.

Reconstructing the life history of a single cell - Cell's unique mutations used to trace history back to its origins in the embryo
http://mnt.to/l/4p9N
Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg.

Salmonella's favorite food could prove to be its undoing
http://mnt.to/l/4p9H
Study suggests that Salmonella’s reliance on one particular nutrient to survive, grow and inflict damage could lead to new treatment for the infection.

Both nature and nurture play a role in developing expertise
http://mnt.to/l/4p9q
Mom or dad may have driven you to cello rehearsal all those years, but you can also thank your genes for pushing you to practice, according to new research led by a Michigan State University...

Simple blood test in development that could help predict the likelihood of a woman developing breast cancer
http://mnt.to/l/4p9g
A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation, according to...

Parkinson's disease researchers offered new insights into causes of this disease
http://mnt.to/l/4p9d
Scientists have taken a step closer to understanding the causes of Parkinson's disease, identifying what's happening at a cellular level to potentially help develop future treatments.

Known breast cancer gene needs a partner to initiate and spread tumors
http://mnt.to/l/4p9c
A study led by Princeton University researchers has revealed that the gene Metadherin - which is implicated in promoting the spread of breast cancer tumors - only stimulates tumor growth when...

----------------------------------------------
** HEART DISEASE News **

Vascular health in indigenous Australians improved by treating gum disease
http://mnt.to/l/4p9b
A simple non-surgical gum disease treatment markedly reduces the thickness of the wall of the arteries, a risk factor for heart disease, according to a first of its kind study among Aboriginal...

----------------------------------------------
** HYPERTENSION News **

Obesity, high blood pressure, high triglycerides, and diabetes increase future risk for chronic kidney disease
http://mnt.to/l/4p97
Risk factors for chronic kidney disease (CKD) are present and identifiable 30 years before diagnosis, according to a study appearing in an upcoming issue of the Journal of the American Society...

----------------------------------------------
** IMMUNE SYSTEM / VACCINES News **

Invisibility cloak for immune cells
http://mnt.to/l/4p8X
The various cells in the immune system have to protect themselves from one another so that they don't kill each other.

----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **

New European research project aims to tackle antibiotic resistance issue raised by WHO via inhalable nano therapeutics
http://mnt.to/l/4pbg
A new research project (PneumoNP) is aimed at tackling antibiotic resistance in respiratory tract infections via the use of inhalable nanotherapeutic compounds.

Researchers developing online visualisation tool to support decision makers in tackling vector borne diseases
http://mnt.to/l/4pb6
An online visualisation tool is currently being developed to support decision makers in taking site specific intervention measures to mitigate the risk of outbreaks and transmission of...

Interferons and viral infections
http://mnt.to/l/4p9y
Respiratory and intestinal infections caused by RNA viruses stimulate infected cells to produce interferons, which can act alone or in combination to block virus replication.

Liver transplants in patients with hepatitis C: virus infection supports organ acceptance
http://mnt.to/l/4p9x
Chronic hepatitis C virus infections are among the most common reasons for liver transplants. Because existing viruses also infect the new liver, the immune system is highly active there.

Resistance to antibiotics: new rapid diagnosis
http://mnt.to/l/4p9w
A rapid diagnostic test for multi-resistance to broad-spectrum antibiotics has just been developed at the University of Fribourg.

Staphylococcus aureus forms slimy 'streamers' to clog up medical devices
http://mnt.to/l/4p9j
A group of researchers from the US has moved a step closer to preventing infections of the common hospital pathogen, Staphylococcus aureus, by revealing the mechanisms that allow the bacteria to...

Vascular health in indigenous Australians improved by treating gum disease
http://mnt.to/l/4p9b
A simple non-surgical gum disease treatment markedly reduces the thickness of the wall of the arteries, a risk factor for heart disease, according to a first of its kind study among Aboriginal...

----------------------------------------------
** IT / INTERNET / E-MAIL News **

Monitoring of kidney transplant patients improved by 'big data' technique
http://mnt.to/l/4p98
A new data analysis technique could radically improve monitoring of kidney transplant patients, according to new research published this week in PLOS Computational Biology.

Care gaps in outpatient settings targeted by e-surveillance program
http://mnt.to/l/4p8T
An innovative framework for identifying and addressing potential gaps in health care in outpatient settings using electronic clinical surveillance tools has been used to target patient safety...

----------------------------------------------
** LIVER DISEASE / HEPATITIS News **

Liver transplants in patients with hepatitis C: virus infection supports organ acceptance
http://mnt.to/l/4p9x
Chronic hepatitis C virus infections are among the most common reasons for liver transplants. Because existing viruses also infect the new liver, the immune system is highly active there.

----------------------------------------------
** MEDICAL DEVICES / DIAGNOSTICS News **

One third of total knee replacements in US are 'inappropriate'
http://mnt.to/l/4pbj
A new study examines Spanish appropriateness criteria for total knee replacement surgery, in response to concerns that the surgery has become overused in the US.

Study urges improvement in physicians' inconsistent record of ordering lab tests
http://mnt.to/l/4p9p
Why does one physician in a walk-in practice order laboratory monitoring tests for patients more often than a colleague working down the hallway?

Staphylococcus aureus forms slimy 'streamers' to clog up medical devices
http://mnt.to/l/4p9j
A group of researchers from the US has moved a step closer to preventing infections of the common hospital pathogen, Staphylococcus aureus, by revealing the mechanisms that allow the bacteria to...

Simple blood test in development that could help predict the likelihood of a woman developing breast cancer
http://mnt.to/l/4p9g
A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation, according to...

----------------------------------------------
** MEDICAL PRACTICE MANAGEMENT News **

Novel organ preservation technique 'stores rat livers for 3-4 days'
http://mnt.to/l/4pc8
A novel four-step preservation technique allowed the livers of rats to be stored for 3-4 days before transplantation. Could the method transform organ transplantation globally?

----------------------------------------------
** MEDICAL STUDENTS / TRAINING News **

Lack of residency positions leaves foreign-trained physicians frustrated
http://mnt.to/l/4p9m
Foreign-trained
physicians feel there are not enough residency positions for them in countries such as Canada and the United States and this information was not communicated to them before they...

----------------------------------------------
** MEN'S HEALTH News **

Fertility treatment outcomes 'dependent on sperm quality, not age of donor'
http://mnt.to/l/4pbd
Many sperm banks do not accept donations from older men. But new research suggests outcomes of fertility treatment are dependent on sperm quality rather than the age of the donor.

Researchers dispute surmise that chronic brain damage is prevalent among NFL players
http://mnt.to/l/4p8P
A study published online in Sports Health: A Multidisciplinary Approach provides a different take on previous information regarding the prevalence of chronic brain damage in retired NFL players.

----------------------------------------------
** MRSA / DRUG RESISTANCE News **

New European research project aims to tackle antibiotic resistance issue raised by WHO via inhalable nano therapeutics
http://mnt.to/l/4pbg
A new research project (PneumoNP) is aimed at tackling antibiotic resistance in respiratory tract infections via the use of inhalable nanotherapeutic compounds.

Resistance to antibiotics: new rapid diagnosis
http://mnt.to/l/4p9w
A rapid diagnostic test for multi-resistance to broad-spectrum antibiotics has just been developed at the University of Fribourg.

Staphylococcus aureus forms slimy 'streamers' to clog up medical devices
http://mnt.to/l/4p9j
A group of researchers from the US has moved a step closer to preventing infections of the common hospital pathogen, Staphylococcus aureus, by revealing the mechanisms that allow the bacteria to...

----------------------------------------------
** MUSCULAR DYSTROPHY / ALS News **

Symptoms of amyotrophic lateral sclerosis exacerbated by over-activity of enzyme HDAC6
http://mnt.to/l/4p9f
Scientists at VIB and KU Leuven have demonstrated in fruit-flies that over-activity of the enzyme HDAC6 in the nerve ends exacerbates the symptoms of the neurodegenerative condition Amyotrophic...

----------------------------------------------
** NEUROLOGY / NEUROSCIENCE News **

Effectiveness of addiction drugs 'depends on phase of addiction'
http://mnt.to/l/4pck
In a model of rats trained to self-administer cocaine, researchers found that efficacy of treatments to control drug-seeking behavior depended on the subject's phase of addiction.

Did eating bugs make our early ancestors more intelligent?
http://mnt.to/l/4pbN
A 5-year study of capuchin monkeys suggests foraging for hard-to-find insects may have helped our early ancestors' brains evolve the thinking ability that led to advanced tool use.

A study shows that child maltreatment influences alcohol consumption in adolescents
http://mnt.to/l/4pb9
A study coordinated by Jorge Manzanares, Professor of Pharmacology at the University Miguel Hernández (UMH) in Elche (Spain), shows that child maltreatment, whatever its form, produces...

Scientists map molecular olfactory signatures of foodstuffs
http://mnt.to/l/4p9s
How are we able to recognize foodstuffs like strawberries, coffee, barbecued meat or freshly boiled potatoes by smell alone? Foodstuffs contain more than 10,000 different volatile substances.

Minimizing stroke injury by blocking key enzyme
http://mnt.to/l/4p9n
A drug that blocks the action of the enzyme Cdk5 could substantially reduce brain damage if administered shortly after a stroke, UT Southwestern Medical Center research suggests.

Symptoms of amyotrophic lateral sclerosis exacerbated by over-activity of enzyme HDAC6
http://mnt.to/l/4p9f
Scientists at VIB and KU Leuven have demonstrated in fruit-flies that over-activity of the enzyme HDAC6 in the nerve ends exacerbates the symptoms of the neurodegenerative condition Amyotrophic...

Parkinson's disease researchers offered new insights into causes of this disease
http://mnt.to/l/4p9d
Scientists have taken a step closer to understanding the causes of Parkinson's disease, identifying what's happening at a cellular level to potentially help develop future treatments.

Brain circuits identified that are involved in stress-induced fevers
http://mnt.to/l/4p95
When we feel mentally stressed, we often also feel physiological changes, including a faster heart rate and an increase in body temperature.

Researchers dispute surmise that chronic brain damage is prevalent among NFL players
http://mnt.to/l/4p8P
A study published online in Sports Health: A Multidisciplinary Approach provides a different take on previous information regarding the prevalence of chronic brain damage in retired NFL players.

Traditional approaches in managing ABI-associated behavior challenged
http://mnt.to/l/4p8N
Individuals with brain injury and their families often struggle to accept the associated personality changes.

----------------------------------------------
** NUTRITION / DIET News **

Did eating bugs make our early ancestors more intelligent?
http://mnt.to/l/4pbN
A 5-year study of capuchin monkeys suggests foraging for hard-to-find insects may have helped our early ancestors' brains evolve the thinking ability that led to advanced tool use.

Impact of sugar on tooth decay remains a major health concern, says FGDP(UK)
http://mnt.to/l/4pb4
It is important that the effect of sugar intake on tooth decay is considered alongside obesity, type 2 diabetes and heart disease as a major public health challenge, according to the Faculty...

Coeliac UK launches new app to help manage a gluten-free diet
http://mnt.to/l/4p9Z
Coeliac UK, the national charity for people with coeliac disease, announces the launch of its new app called 'Gluten-free on the Move'.

Salmonella's favorite food could prove to be its undoing
http://mnt.to/l/4p9H
Study suggests that Salmonella’s reliance on one particular nutrient to survive, grow and inflict damage could lead to new treatment for the infection.

----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **

Obesity, high blood pressure, high triglycerides, and diabetes increase future risk for chronic kidney disease
http://mnt.to/l/4p97
Risk factors for chronic kidney disease (CKD) are present and identifiable 30 years before diagnosis, according to a study appearing in an upcoming issue of the Journal of the American Society...

Pre-pregnancy obesity associated with earliest preterm births
http://mnt.to/l/4p8S
Women who are obese before they become pregnant face an increased risk of delivering a very premature baby, according to a new study of nearly 1 million California births.

----------------------------------------------
** PAIN / ANESTHETICS News **

Multi-study analysis reinforces value of EXPAREL-based multimodal analgesia regimen
http://mnt.to/l/4p9X
Pacira Pharmaceuticals, Inc. has announced results from a pooled analysis of IMPROVE, a series of open-label prospective, Phase 4 clinical studies designed to compare postsurgical narcotic use...

----------------------------------------------
** PARKINSON'S DISEASE News **

Parkinson's disease researchers offered new insights into causes of this disease
http://mnt.to/l/4p9d
Scientists have taken a step closer to understanding the causes of Parkinson's disease, identifying what's happening at a cellular level to potentially help develop future treatments.

----------------------------------------------
** PEDIATRICS / CHILDREN'S HEALTH News **

A study shows that child maltreatment influences alcohol consumption in adolescents
http://mnt.to/l/4pb9
A study coordinated by Jorge Manzanares, Professor of Pharmacology at the University Miguel Hernández (UMH) in Elche (Spain), shows that child maltreatment, whatever its form, produces...

Countdown to 2015 and beyond: fulfilling the health agenda for women and children
http://mnt.to/l/4pb5
The Lancet is publishing a new Review from the Countdown to 2015 collaboration, summarising results from the Countdown 2014 report, examining the data supporting evidence-based decisions in...

Published data shows long-term efficacy of Elvanse® (lisdexamfetamine dimesylate) in children and adolescents with ADHD
http://mnt.to/l/4pb2
A new paper published in the Journal of the American Association of Children and Adolescent Psychiatry (JAACAP) shows long-term efficacy of lisdexamfetamine dimesylate (LDX) in children and...

Psychostimulants and cardiovascular risk in children with ADHD
http://mnt.to/l/4p9k
Psychostimulant use to treat children and adolescents with attention-deficit/hyperactivity disorder (ADHD) is increasing worldwide, and the evaluation of the cardiovascular safety of stimulant...

Reducing home secondhand smoke exposure through motivational interviewing
http://mnt.to/l/4p8W
A Johns Hopkins-led research team has found that motivational interviewing, along with standard education and awareness programs, significantly reduced secondhand smoke exposure among children...

Caregivers' allergy perceptions not always accurate
http://mnt.to/l/4p8R
It's tough being the parent of a child with food allergies. Constant vigilance is needed for everything your child eats, when a single food item containing a hidden ingredient can be fatal.

Structure, protein elements revealed that are critical to human function and disease
http://mnt.to/l/4p8Q
New structures discovered within cilia show a relationship between certain proteins and juvenile myoclonic epilepsy.

----------------------------------------------
** PHARMA INDUSTRY / BIOTECH INDUSTRY News **

Chemists find silver lining in drug manufacture
http://mnt.to/l/4p9h
Chemists at Queen Mary University of London have discovered a new chemical to aid drug manufacturing processes, making it more environmentally-friendly and easier to scale up for industry.

----------------------------------------------
** PHARMACY / PHARMACIST News **

Study urges improvement in physicians' inconsistent record of ordering lab tests
http://mnt.to/l/4p9p
Why does one physician in a walk-in practice order laboratory monitoring tests for patients more often than a colleague working down the hallway?

Care gaps in outpatient settings targeted by e-surveillance program
http://mnt.to/l/4p8T
An innovative framework for identifying and addressing potential gaps in health care in outpatient settings using electronic clinical surveillance tools has been used to target patient safety...

----------------------------------------------
** PREGNANCY / OBSTETRICS News **

Fertility treatment outcomes 'dependent on sperm quality, not age of donor'
http://mnt.to/l/4pbd
Many sperm banks do not accept donations from older men. But new research suggests outcomes of fertility treatment are dependent on sperm quality rather than the age of the donor.

Pre-pregnancy obesity associated with earliest preterm births
http://mnt.to/l/4p8S
Women who are obese before they become pregnant face an increased risk of delivering a very premature baby, according to a new study of nearly 1 million California births.

----------------------------------------------
** PRIMARY CARE / GENERAL PRACTICE News **

Study urges improvement in physicians' inconsistent record of ordering lab tests
http://mnt.to/l/4p9p
Why does one physician in a walk-in practice order laboratory monitoring tests for patients more often than a colleague working down the hallway?

Lack of residency positions leaves foreign-trained physicians frustrated
http://mnt.to/l/4p9m
Foreign-trained
physicians feel there are not enough residency positions for them in countries such as Canada and the United States and this information was not communicated to them before they...

Care gaps in outpatient settings targeted by e-surveillance program
http://mnt.to/l/4p8T
An innovative framework for identifying and addressing potential gaps in health care in outpatient settings using electronic clinical surveillance tools has been used to target patient safety...

Researchers estimate 5.8 million A&E visits occur after patients unable to see a GP in England
http://mnt.to/l/4p8w
Unplanned attendances at accident and emergency (A&E) departments in England have increased by 11 per cent (2.2 million attendances) between financial years 2008-2009 and 2012-2013.

----------------------------------------------
** PROSTATE / PROSTATE CANCER News **

Breast, prostate and colorectal cancer: 'family history bigger factor than lifestyle'
http://mnt.to/l/4pc7
Family history is a greater risk factor than lifestyle for developing some cancers, according to a Swedish study looking at 71,000 adopted people.

----------------------------------------------
** PSYCHOLOGY / PSYCHIATRY News **

Family worries can cause conflict at work
http://mnt.to/l/4pb8
Worrying about family problems during work time increases conflict with work colleagues, which can lead to spousal arguments at home in the evening.

Brain function when aging adversely affected by little or poor sleep
http://mnt.to/l/4p9v
Research published in PLOS ONE by researchers at the University of Warwick indicates that sleep problems are associated with worse memory and executive function in older people.

Researchers explain the link between language and emotions
http://mnt.to/l/4p9r
A team of researchers headed by the Erfurt-based psychologist Prof. Ralf Rummer and the Cologne-based phoneticist Prof.

Psychostimulants and cardiovascular risk in children with ADHD
http://mnt.to/l/4p9k
Psychostimulant use to treat children and adolescents with attention-deficit/hyperactivity disorder (ADHD) is increasing worldwide, and the evaluation of the cardiovascular safety of stimulant...

Brain circuits identified that are involved in stress-induced fevers
http://mnt.to/l/4p95
When we feel mentally stressed, we often also feel physiological changes, including a faster heart rate and an increase in body temperature.

Traditional approaches in managing ABI-associated behavior challenged
http://mnt.to/l/4p8N
Individuals with brain injury and their families often struggle to accept the associated personality changes.

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** PUBLIC HEALTH News **

New research to improve health challenges in seven day hospital care
http://mnt.to/l/4pbf
The lottery of patient prognosis determined by the time of day, and day of the week that a patient is admitted to hospital is to be challenged thanks to a new research collaboration between...

Impact of sugar on tooth decay remains a major health concern, says FGDP(UK)
http://mnt.to/l/4pb4
It is important that the effect of sugar intake on tooth decay is considered alongside obesity, type 2 diabetes and heart disease as a major public health challenge, according to the Faculty...

Autism and driving: first study asks autistic adults about real-world driving experiences
http://mnt.to/l/4p9z
In the first pilot study asking adults on the autism spectrum about their experiences with driving, researchers at Drexel University found significant differences in self-reported driving...

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** RESPIRATORY / ASTHMA News **

Interferons and viral infections
http://mnt.to/l/4p9y
Respiratory and intestinal infections caused by RNA viruses stimulate infected cells to produce interferons, which can act alone or in combination to block virus replication.

Reducing home secondhand smoke exposure through motivational interviewing
http://mnt.to/l/4p8W
A Johns Hopkins-led research team has found that motivational interviewing, along with standard education and awareness programs, significantly reduced secondhand smoke exposure among children...

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** SENIORS / AGING News **

Brain function when aging adversely affected by little or poor sleep
http://mnt.to/l/4p9v
Research published in PLOS ONE by researchers at the University of Warwick indicates that sleep problems are associated with worse memory and executive function in older people.

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** SLEEP / SLEEP DISORDERS / INSOMNIA News **

Brain function when aging adversely affected by little or poor sleep
http://mnt.to/l/4p9v
Research published in PLOS ONE by researchers at the University of Warwick indicates that sleep problems are associated with worse memory and executive function in older people.

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** SMOKING / QUIT SMOKING News **

Reducing home secondhand smoke exposure through motivational interviewing
http://mnt.to/l/4p8W
A Johns Hopkins-led research team has found that motivational interviewing, along with standard education and awareness programs, significantly reduced secondhand smoke exposure among children...

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** SPORTS MEDICINE / FITNESS News **

Researchers dispute surmise that chronic brain damage is prevalent among NFL players
http://mnt.to/l/4p8P
A study published online in Sports Health: A Multidisciplinary Approach provides a different take on previous information regarding the prevalence of chronic brain damage in retired NFL players.

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** STROKE News **

Minimizing stroke injury by blocking key enzyme
http://mnt.to/l/4p9n
A drug that blocks the action of the enzyme Cdk5 could substantially reduce brain damage if administered shortly after a stroke, UT Southwestern Medical Center research suggests.

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** TRANSPLANTS / ORGAN DONATIONS News **

Novel organ preservation technique 'stores rat livers for 3-4 days'
http://mnt.to/l/4pc8
A novel four-step preservation technique allowed the livers of rats to be stored for 3-4 days before transplantation. Could the method transform organ transplantation globally?

Liver transplants in patients with hepatitis C: virus infection supports organ acceptance
http://mnt.to/l/4p9x
Chronic hepatitis C virus infections are among the most common reasons for liver transplants. Because existing viruses also infect the new liver, the immune system is highly active there.

'Big data' technique improves monitoring of kidney transplant patients
http://mnt.to/l/4p9t
A new data analysis technique radically improves monitoring of kidney patients, according to a University of Leeds-led study, and could lead to profound changes in the way we understand our...

Monitoring of kidney transplant patients improved by 'big data' technique
http://mnt.to/l/4p98
A new data analysis technique could radically improve monitoring of kidney transplant patients, according to new research published this week in PLOS Computational Biology.

Sharing strategy adopted by Tennessee and Florida may serve as model to reduce geographic disparities in US kidney allocation policy
http://mnt.to/l/4p96
In 2011, nearly 17,000 kidney transplants were performed in the United States, but 94,000 patients remained on the waiting list.

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** TROPICAL DISEASES News **

Researchers developing online visualisation tool to support decision makers in tackling vector borne diseases
http://mnt.to/l/4pb6
An online visualisation tool is currently being developed to support decision makers in taking site specific intervention measures to mitigate the risk of outbreaks and transmission of...

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** UROLOGY / NEPHROLOGY News **

'Big data' technique improves monitoring of kidney transplant patients
http://mnt.to/l/4p9t
A new data analysis technique radically improves monitoring of kidney patients, according to a University of Leeds-led study, and could lead to profound changes in the way we understand our...

Monitoring of kidney transplant patients improved by 'big data' technique
http://mnt.to/l/4p98
A new data analysis technique could radically improve monitoring of kidney transplant patients, according to new research published this week in PLOS Computational Biology.

Sharing strategy adopted by Tennessee and Florida may serve as model to reduce geographic disparities in US kidney allocation policy
http://mnt.to/l/4p96
In 2011, nearly 17,000 kidney transplants were performed in the United States, but 94,000 patients remained on the waiting list.

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** VETERINARY News **

Did eating bugs make our early ancestors more intelligent?
http://mnt.to/l/4pbN
A 5-year study of capuchin monkeys suggests foraging for hard-to-find insects may have helped our early ancestors' brains evolve the thinking ability that led to advanced tool use.

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** WOMEN'S HEALTH / GYNECOLOGY News **

Countdown to 2015 and beyond: fulfilling the health agenda for women and children
http://mnt.to/l/4pb5
The Lancet is publishing a new Review from the Countdown to 2015 collaboration, summarising results from the Countdown 2014 report, examining the data supporting evidence-based decisions in...

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