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Prevalence of Opioid Use By SSDI Recipients is High: Medical Care Report

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Prevalence of opioid use is over 20 percent and rising, and more than 40 percent of Social Security Disability Insurance (SSDI) recipients take opioid pain relievers, reports a study in the September issue of iMedical Care/i. The journal is published by Lippincott Williams (and) Wilkins, a part of Wolters Kluwer Health. The high proportion of SSDI recipients who are chronic opioid users-in many, at high and very high daily doses-"is worrisome in light of established ...

Health Issues Risk in Taiwanese Women With Husband's Declining Health

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Stress, anxiety and uncertainty are all associated with death of a spouse, but husband's declining health could put Taiwanese women at risk for health issues. This was reported by Princeton University's Woodrow Wilson School of Public and International Affairs, along with quantification of this stress. Using data from a longitudinal sample of Taiwanese older adults, the researchers found that the more a husband suffered, the more his wife's glucose levels increased. ...

Great Barrier Reef Threatened by Climate Change: GBRMPA

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Australia's Great Barrier Reef has been deteriorating despite conservation efforts and is only expected to worsen, reveals a report. A five-yearly report released by the Great Barrier Reef Marine Park Authority (GBRMPA) said that the overall outlook of the site was poor and that climate change posed the biggest threat to the site, reported the BBC. The report also added that poor quality of water from land-based run off, coastal development and fishing ...

Immune Cells Kept in Check from Turning Against the Body by Genetic Signal

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Previous research has shown that when faced with pathogens, the immune system summons a swarm of cells made up of soldiers and peacekeepers. The peacekeeping cells tell the soldier cells to halt fighting when invaders are cleared. Without this cease-fire signal, the soldiers, known as killer T cells, continue their frenzied attack and turn on the body, causing inflammation and autoimmune disorders such as allergies, asthma, rheumatoid arthritis, multiple sclerosis ...

Export of Human Hair by Chinese County to Africa

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Human-hair filled sacks spill onto the streets of a rural county whose farmers have helped make China the world's biggest exporter of products made from the material. As dawn broke over the morning market in Taihe, vendors bringing hairy wares from across China haggled with dozens of buyers, and tempers frayed. "We have to bargain for hair," said buyer Liu Yanwen, 35, who sported a buzzcut and arrived at the market at 5.30 am in search of deals. "We ...

Scientists Successfully Target Common Mutation in Lou Gehrig's Disease and Frontotemporal Dementia

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A therapeutic strategy targeting a specific genetic mutation that causes a common form of amyotrophic lateral sclerosis (ALS), better known as Lou Gehrig's disease, as well a type of frontotemporal dementia (FTD) has been designed by an international team led by scientists from the Florida campuses of The Scripps Research Institute (TSRI) and the Mayo Clinic. The scientists developed small-molecule drug candidates and showed they interfere with the synthesis of ...

Scientists Create Tissue Development 'Roadmap' to Guide Stem Cell Medicine

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A computer algorithm called CellNet has been created as a "roadmap" for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies. This feat has been accomplished by scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University. CellNet and its application to stem cell engineering are described in two back-to-back ...

Discussion of Ebola Drug by Tekmira Lab With WHO

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Tekmira, a Canadian lab, is in touch with the World Health Organization and government agencies to discuss over the possible use of its experimental Ebola drug in West Africa, the company said. The epidemic has claimed more than 1,000 lives, mainly in Sierra Leone, Liberia and Guinea, but has no proven cure or vaccine, prompting authorities to consider experimental options to stem the outbreak. Tekmira has been in touch with regulatory authorities to ...

Human Milk Fat Improves Growth in Premature Infants: Study

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A cream supplement incorporated into premature infants' diets improved their growth outcomes in the neonatal intensive care unit, revealed study. The report appears today in the iJournal of Pediatrics/i. "For premature babies who weigh less than 1,000 grams (about 2 pounds, 2 ounces), one of the problems is that their lungs and other organs are still developing when they are born. If the infant gains weight and increases in length at a good rate while in the ...

Breast Cancer Recurrence Rate in Overweight and Obese Women Lowered by NSAIDs

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In overweight and obese women who used aspirin or other nonsteroidal anti-inflammatory drugs regularly, the recurrence of hormone-related breast cancer was cut by half, found in a data published in Cancer Research, a journal of the American Association for Cancer Research. "Our studies suggest that limiting inflammatory signaling may be an effective, less toxic approach to altering the cancer-promoting effects of obesity and improving patient response to hormone ...

Fukushima Radiation Caused Serious Damage to Wildlife

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Fukushima radiation has affected wildlife population, genetic makeup and the repair mechanisms of birds, monkeys, butterflies, and other insects to cope with the exposure, revealed study. Pale grass blue butterfly, one of the most common butterfly species in Japan, collected from the site of the 2011 nuclear disaster in Japan showed size reduction, slowed growth, high mortality and morphological abnormality. Butterflies that were bred in the laboratory with parents ...

Computer-bypass Commands from Brain to Legs

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Signals for rhythmic movements can be produced in the spinal cord, locomotion center, to enable movements such as swimming and walking, even when isolated from the brain. The brain controls spinal locomotion center by sending command to the spinal locomotion center to start, stop and change waking speed. In most cases of spinal cord injury, the loss of this link from the brain to the locomotion center causes problems with walking. The research group came up with ...

Benefits of Vitamin a Cancer Therapy Blocked by Protein

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A form of vitamin A, Retinoic acid, is used to treat and help prevent the recurrence of a variety of cancers, however, some patients do not benefit from the drug. The reason for this resistance was unclear until this week when researchers from Virginia Commonwealth University (VCU) Massey Cancer Center demonstrated that a protein known as AEG-1 blocks the effects of retinoic acid in leukemia and liver cancer. Because AEG-1 is overexpressed in nearly every cancer, these findings ...

Higher Risk of Common Cancers With Excess Body Weight

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Being overweight increases the risk of 10 common cancers, suggested a study of five million UK adults that prompted a call Thursday for tougher anti-obesity measures. Researchers calculated that 12,000 cases of these 10 cancers every year in the UK were attributable to excess body weight. And if current trends continue, "there could be over 3,500 extra cancers every year as a result," said a statement issued with the study, the largest of its kind, published ...

Excess Salt Linked to 1.65 Million Deaths Per Year

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People around the world consume twice as much salt they are recommended and this contributes to 1.65 million heart-related deaths per year, researchers said Wednesday. Excess salt can cause high blood pressure, which is leading factor in heart disease and stroke, according to the study in the New England Journal of Medicine. Led by scientists at Harvard and Tufts University, the study combined data from 205 surveys of sodium intake in 66 countries around ...

Increased Suicide Risk in Older Adults With Poor Sleep Quality

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Reported poor sleep quality appears to be associated with an increased risk for suicide in older adults, independent of a depressed mood. The study was written by Rebecca A. Bernert, Ph.D., of the Stanford University School of Medicine, California, and colleagues Suicide is a preventable public health problem and accounts for almost 1 million deaths annually worldwide. Late life is characterized by an increased prevalence of sleep complaints and disproportionately ...

Mechanism That Stops Progression of Abnormal Cells into Cancer Identified

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A tumor suppressor pathway, called the Hippo pathway, is responsible for sensing abnormal chromosome numbers in cells and triggering cell cycle arrest, thus preventing progression into cancer, researchers from Boston University School of Medicine (BUSM) reveal. Although the link between abnormal cells and tumor suppressor pathways-like that mediated by the well known p53 gene-has been firmly established, the critical steps in between are not well understood. According ...

Dangerous Sepsis in Animal Models Controlled With Treatment With Lymph Node Cells

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Severe cases of sepsis may be halted by an immune-regulating cell present in lymph nodes. Sepsis is an out-of-control inflammatory response that can lead to organ failure and death. In the August 13 issue of iScience Translational Medicine/i, a multi-institutional research team reports that treatment with fibroblastic reticular cells (FRCs) significantly improved survival in two mouse models of sepsis, even when delivered after the condition was well established. ...

Pizza Vending Machine

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A vending machine in Westfield Chatswood dispenses margherita pizzas in less than three minutes. Restaurateur George Pompei's latest Italian-made import, called Pizza Gio, which costs 40,000 dollars, is 2m by 1.78m brown boxcooks and dispenses 11 inch 12 dollars full-sized pizzas, News.com.au reported. Pompei said that the quality was the same as his Bondi restaurant Pompei's, where dough was made using stoneground flour, natural yeast, extra virgin ...

Brain 'Switchboard' Important in Attention and Sleep Discovered

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Scientists have discovered a new brain switchboard which is important in attention and sleep. In experiments with alert mice, Dr. Halassa's group found that sensory TRN cells fired very little. This suggested that while these neurons block the flow of external information during sleep, they facilitate the flow of information when an animal is awake and alert. By contrast, TRN cells that control the flow of internal signals behaved in an opposite ...

Genetically Edited Fruit, Coming Soon

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Recent advances in the field of genome editing have paved way for fruits and other crops to be genetically improved without the need to introduce foreign genes, says study published in iTrends in Biotechnology/i on August 13th. With awareness of what makes these biotechnologies new and different, genetically edited fruits might be met with greater acceptance by society at large than genetically modified organisms (GMOs) so far have been, especially in Europe, ...