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Preterm Birth: Subtle but Important Memory Function Affected

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A new study has revealed that children born prematurely show differences in a subtle but important aspect of memory: the ability to form and retrieve memories about context, such as what, when, and where something happened. This type of memory is important, but can be missed on the usual set of direct assessments. The new research suggests that it may be valuable to find targeted ways to help strengthen this aspect of memory in children born preterm. The ...

OPD and Day Care Procedures are Expensive - Are They Covered by Insurance?

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When a person needs an MRI scan which costs approximately Rs. 10,000 will it be covered by your family floater health policy? It is most probably not covered. Diagnostic tests may lead to treatment in the outpatient department (OPD) and many of these procedures which do not require hospitalization are very expensive - it would be wiser to buy a policy which covers OPD treatment. "For an insurance company, the key is whether or not a line of treatment has been applied. ...

Behavioral Inhibition During Infancy Linked to Adolescent Social Anxiety

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Behavioral inhibition that persists across early childhood is associated with social anxiety in adolescence, but only among youth who were insecurely attached to their parents as infants, according to researchers at the University of Maryland and the National Institute of Mental Health and the University of Waterloo. Infants who react to unfamiliar objects, people and situations by becoming afraid and withdrawing are referred to as having a behaviorally inhibited temperament. ...

Loss of Sirtuin Enzyme Drives Formation of Early Prostate Cancer

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Mice studies have revealed that loss of one of sirtuin (SIRT1) enzyme drives the formation of early prostate cancer (prostatic intraepithelial neoplasia, PIN). SIRT1 can defend the cell against damage from free radicals. Researchers created a mouse model that lacked SIRT1. Normally SIRT1 proteins help activate a mitochondrial protein called SOD2, in turn activating those proteins to keep free-radical levels in check. When SIRT1 levels diminish, SOD2 is no longer effective ...

53 Existing Drugs can Prevent Ebola Infection

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There are 53 already approved drugs, including cancer drugs, antihistamines and antibiotics that may block the Ebola virus from entering human cells, according to researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH). Microtubule inhibitors used to treat cancer were found to be the most effective in hindering infection by an Ebola virus. Lead author Dr. Adolfo Garcia-Sastre said, "There was an urgent need to rapidly develop ...

Drug Allergies Triggered by Protein Receptor MRGPRX2

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Researchers from Johns Hopkins and University of Alberta have identified a single protein receptor, MRGPRX2, as the root of painful and dangerous allergic reactions to medications and other substances. Finding a new drug that targets the problematic protein could help smoothen treatment for patients with prostate cancer, diabetes and even HIV. Previous studies have linked reactions (such as pain, itching and rashes at the injection sites of many drugs) to part of the ...

Resisting Cancer Will be Futile

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Katherine Borden, from University of Montreal's Institute for Research in Immunology and Cancer (IRIC) has evoked Star Trek's Borg in her fight against Cancer. "Cancer cells rapidly evolve a multitude of defense mechanisms to evade the effects of the oncologist's drug arsenal. Unfortunately, clinical strategies to overcome these lag far behind," Borden explained. "This mismatch likely underlies our inability to implement new durable treatment strategies." However, ...

Food Allergy in Kids Need Specialized Support from Dieticians

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Making food choices for your child after discovering a severe food allergy is a sure challenge for parents. Even more stressful can be determining what foods your child can and cannot eat, and constructing a new diet which might eliminate entire categories of foods. A new study published in the iAnnals of Allergy, Asthma and Immunology/i, says that providing parents with detailed, individual advice from a dietician is a key component of effective care. "We ...

Contaminated Vials of Preservative-free Drugs Killed 64 People

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In connection with a 2012 outbreak of meningitis that killed 64 people across nine states, two owners and 12 former employees of a US pharmacy were arrested Wednesday, prosecutors said. Barry Cadden and Gregory Conigliaro owned the New England Compounding Center (NECC), which lost its license in 2012 after inspectors found it guilty of multiple sanitary violations. The pharmacy, located in the city of Framingham, Massachusetts in the US northeast, voluntarily ...

Inappropriate Use of Epinephrine Auto-injectors and Asthma Inhalers

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Medical devices are prescibed to help relieve symptoms and sometimes, to treat potentially fatal allergic reactions. Millions of Americans with severe allergies and asthma are prescribed such devices and unfortunately, very few people use their prescribed medical devices properly, though they think that they know the directions of use. According to a new study published in the iAnnals of Allergy, Asthma and Immunology,/i the scientific publication of the American ...

Increase in Global Life Expectancy

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Despite increased rate of liver cancer and chronic kidney deaths, the average life expectancy is 71.5 years in 2013, from 65.3 years in 1990. Global life expectancy rose by 5.8 years in men and 6.6 years in women between 1990 and 2013. The increase was attributed to falling death rates from cancers (down by 15 percent) and cardiovascular disease (down by 22 percent) in high-income regions of the world. In less affluent regions, it was attributed to rapidly ...

Fracking Banned in New York

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Hydraulic Fracking would be banned in New York State, said Governer Andrew Cuomo, citing health concerns about the controversial oil and gas drilling technique. The announcement extends a de facto New York ban on the practice, which offers the potential to unlock vast quantities of natural gas but which has come under intense scrutiny from environmentalists. The energy industry complains that New York has lost jobs and investment by not following neighboring ...

Benzodiazepine Use is Highest Among Older People, Despite Risks

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Benzodiazepines, a widely used class of sedative and anti-anxiety medications, is increasingly prescribed with advancing age, despite the known risks for older people. This was revealed in a comprehensive analysis of benzodiazepine prescribing in the United States. Given existing guidelines cautioning health providers about benzodiazepine use among older adults, findings from the National Institutes of Health-funded study raise questions about why so many prescriptions--many ...

Migraine May Double Risk for Facial Paralysis

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Bell's palsy, a nervous system condition that causes facial paralysis, is more likely to occur in people with migraine headache, reveals a new study published in the December 17, 2014, online issue of iNeurology/i (Regd) , the medical journal of the American Academy of Neurology. Bell's palsy affects between 11 and 40 per 100,000 people each year. Most people with Bell's palsy recover completely. Headaches are the most common disorder of the nervous system and affect ...

Natural Ways to Increase Platelet Count during Dengue

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Dengue an infectious disease and can lead to fatal complication like bleeding due to low platelet count. Natural remedies can help improve the count.

More Research Required on Medical Marijuana for Brain Diseases: AAN

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More research is required on the use of medical marijuana for brain, spine and nervous system disorders, said the American Academy of Neurology, in a new position statement released by the AAN. The ANN the world''s largest association of neurologists with more than 28,000 members. "The current medical marijuana legislation being passed by policymakers across the country, which promotes marijuana-based products as treatment options for various brain and nervous ...

New Approach to Diagnose Blood Clots in Lungs

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Pulmonary embolisms, the deadly blood clots in the lungs, can be ruled out by a newly identified "sliding scale" model. Researchers from Intermountain Medical Center in Salt Lake City say that it is more accurate than current diagnostic methods. The new model, which factors in a patient's age, more accurately identifies a patient's risk of the often-deadly blood clots and can more easily rule out the need for additional, more invasive tests, helping to reduce unnecessary ...

53 Approved Drugs Identified by Researchers may Block Ebola Infection

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Ebola virus may be prevented from entering human cells, in the process of infection by 53 existing drugs. Researchers found 53 existing drugs that may keep the a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH). Among the better known drug types shown to hinder infection by an Ebola virus model are several cancer drugs, antihistamines and antibiotics. ...

WHO: Ebola Death Toll Rises To Over 6,900

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Ebola death toll rises to over 6,900, almost all of them in west Africa, said the World Health Organization on Wednesday, with Guinea, Liberia and Sierra Leone being the worst affected. As of December 14, there were 18,569 cases of infection of the deadly virus in the three worst affected countries and 6,900 deaths. This is out of a total of 18,603 cases and 6,915 deaths across eight countries affected by the outbreak. In some good news, ...

Toxic Punch of Experimental Anti-Cancer Drug Overcome by 'Sugar-Coated' Microcapsule

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A sugar-based molecular microcapsule has been developed, which eliminates the toxicity of an anticancer agent, 3-bromopyruvate, or 3BrPA, developed by researchers at John Hopkins University. The agent, 3BrPA, was developed a decade ago at Johns Hopkins, in studies of mice with implants of human pancreatic cancer. The encapsulated drug packed a potent anticancer punch, stopped the progression of tumors in the mice, but without the usual toxic effects. "We developed ...

Greater Antibody Response for High-Dose Flu Vaccine in Older Adults

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The high-dose influenza vaccine appears to be a better option than the regular shot, producing a stronger immune response than the standard vaccine in older adults. High-dose vaccine may play a key role, along with improving vaccination rates among health care workers and other strategies, in preventing flu in this vulnerable and growing population according to a study published in iThe Journal of Infectious Diseases/i. About 90 percent of the deaths associated ...

Importance of Fat in the Diet

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Fat along with protein and carbohydrate are essential nutrients for normal body function and for maintaining our well-being.

Cancer can be Detected at Cellular Level With Lens-Free Microscope

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A lens-free microscope developed by UCLA researchers can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes. The invention could lead to less expensive and more portable technology for performing common examinations of tissue, blood and other biomedical specimens. It may prove especially useful in remote areas and in cases where large numbers of samples need to be examined ...

Exposure of Pregnant Women to Air Pollution Increases Chance of Autism in Offspring

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A study from Harvard School of Public Health reported that pregnant women exposed to high levels of fine particulate might have twice the risk of having a child with autism. Researchers found that the risk increased with the exposure particularly during the third trimester. "Our data add additional support to the hypothesis that maternal exposure to air pollution contributes to the risk of autism spectrum disorders," said Marc Weisskopf, Associate professor of ...

Photographer Tackles Obesity by Self Photography

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Photographer Jen Davis has always been comfortable in front as well as behind the camera. Davis began photographing herself in everyday situations, initially choosing images that were "safe and easy" such as hanging out her washing or having a meal with a friend. Just published in a book entitled "11 Years", Davis came up with the idea in 2002 when she was a student. "I was at the beach on a spring break vacation. I guess I hadn't been in a bathing suit for ...

Faulty Stem Cells Found in Duchenne Muscular Dystrophy

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Mice with a form of Duchenne muscular dystrophy, like human patients, undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers at the Stanford University School of Medicine have found that the fault may lie at least partly in the stem cells that surround the muscle fibers. They've found that during the course of the disease, the stem cells become less able to make new muscle and instead begin to express genes involved ...

Common Gene Mutation in ALS Causes Damage in Brain

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A common gene mutation in Amyotrophic lateral sclerosis generates a deadly protein that may cause the damage in the brain that leads to the condition, reveals a new study published online on Thursday (December 17th) in the Cell Press journal iNeuron/i. Researchers look to understand the causes of amyotrophic lateral sclerosis (ALS), in the hope of finding new ways to treat the disease. About 5 percent of ALS patients carry an altered version of a gene called ...

Former Guatemala Gum Growers Settle Down in Sustainable Jungle

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Juan Trujillo sings an old song known to Carmelita settlers living deep in northern Guatemala's Mayan Jungle, waving his hands as if conducting an invisible orchestra. He walks through the hundred-year-old community, whose roots are deeply intertwined with that of the sapodilla tree, whose chicle resin was once widely used in chewing gum. But the people of Carmelita now have a new livelihood: protecting the largest nature reserve in Mesoamerica. Nestled ...

New Class of Synthetic Organic Compounds Mimics Antibodies

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Yale University lab has crafted the first ever synthetic molecules that have both the targeting and response functions of antibodies. The new molecules -- synthetic antibody mimics (SyAMs) -- attach themselves simultaneously to disease cells and disease-fighting cells. The result is a highly targeted immune response, similar to the action of natural human antibodies. "Unlike antibodies, however, our molecules are synthetic organic compounds that are ...

UN Chief Has Left for a Visit to Ebola-hit Countries

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UN Secretary General Ban Ki-moon has left for a visit to Ebola-hit countries to take stock of international efforts to beat back the deadly ebola epidemic. Ban will travel to Ghana, where the United Nations Ebola mission is headquartered; and Guinea, Liberia, Sierra Leone and Mali, where the UN is leading the response to the health crisis. He said, "I want to see the response for myself and show solidarity for those affected." The visit follows sharp criticism ...

Stroke Patients Experience Superior Outcomes With Intra-Arterial Treatment

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Intra-arterial treatment, also called endovascular or interventional treatment, involves working inside the artery to remove the clot. Penumbra, Inc., the market leader in intra-arterial stroke treatment, announced that an independent study published online in the iNew England Journal of Medicine/i found that intra-arterial stroke treatment, including the company's clot extraction technology, was shown to be significantly more effective than medical management ...

Genetic Variations Associated With Type-2 Diabetes in Mexican-Americans

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Researchers at Wake Forest Baptist Medical Center conducted a study to examine the underlying causes that predispose people of Mexcian ancestry than people of European ancestry to develop Type 2 diabetes. Lead author of the study Nicholette Allred, Ph.D said, "Type 2 diabetes is really about how you dispose of your glucose - how long it sits in your bloodstream and how your organs react. With Type 2 diabetes, there is interplay between insulin release from the pancreas ...

New Method for Joining Complex Organic Molecules Like Olefins With Functional Groups or Heteroatoms

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Chemists at The Scripps Research Institute (TSRI) have invented a powerful method for joining complex organic molecules like olefins with heteroatoms or functional groups. This new method does not require the use of extreme temperatures or pressures, nor harsh chemicals. Therefore, portions of the building blocks used that are particularly fragile remain unaltered by the reaction. This method will have immediate application to pharmaceuticals, materials, and agricultural and ...

AUTS2 Gene Mutation Which is Linked to Autism Disorders, Stimulates Other Genes in Early Brain Development

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Epigenetic changes can activate or repress genes involved in autism spectrum disorders (ASDs) and early brain development, according to biochemists at NYU Langone Medical Center. Mice studies and laboratory experiments have revealed that epigenetic changes removed the blocking mechanism of a protein complex long known for gene suppression, and transitioned the complex to a gene activating role instead. Researchers showed that autism susceptibility candidate gene 2 (AUTS2) ...