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More Evidence to Link Saturated Fat Intake and Coronary Heart Disease

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Researchers have analyzed data from a prospective cohort study and come up with more evidence to link saturated fat intake with coronary heart disease. In this week's IPLoS Medicine/I, Kay-Tee Khaw of the University of Cambridge, UK and colleagues analyze data from a prospective cohort study and show associations between plasma concentrations of saturated phospholipid fatty acids and risk of coronary heart disease, and an inverse association between omega-6 ...

Despite New Polio Vaccines, Polio Vaccination Programs Not Reaching Enough Children in Afghanistan and Pakistan

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Not enough children are being vaccinated in Pakistan and Afghanistan despite new, more effective vaccines being introduced to step up the drive to eradicate polio. According to a study published in the iLancet/i medical journal today, sharp declines in vaccine uptake led to a rise in the number of new infections between 2006 and 2011, even though new vaccines introduced during this time have proven to be more effective against the main circulating strain of ...

Brazil Has Laws to Beat Obesity and Protect Against 'Big Food' and 'Big Snack'

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Prompted by civil society organizations, the Brazilian government has passed laws to protect and improve its traditional food system and prevent transnational food chains from affecting public health. This government move stands in contrast to the governments of many industrialized countries that have partly surrendered their prime duty to protect public health to transnational food companies, argue nutrition and public health experts writing in this week's IPLoS ...

Effective Treatment for Common Liver Disease Possible With New Animal Model

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The laboratory opossum has been developed as a new animal model by scientists at Texas Biomed to study the most common liver disease in US - afflicting up to 15 million Americans - and for which there is no cure. The condition, nonalcoholic steatohepatitis (NASH), resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major feature of NASH is accumulation of fat in the liver, along with inflammation and functional damage. Most ...

60 Children In Cambodia Die of Mysterious Disease: WHO

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Unknown disease has cost the life of 60 young children in Cambodia in three months, announced the World Health Organization on Tuesday as it pursued to find the cause. "The number of deaths reported to WHO is 60 cases and they have all been in young children," said Dr Nima Asgari, a public health specialist for the UN body in Cambodia, adding that the first casualties were reported in April. The WHO is currently working with the Cambodian Ministry of ...

Brain Receptor for Fantasy Identified

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A new transmitter substance in the brain best known as the illegal drug fantasy has been discovered by researchers. In the 1960s, gamma-hydroxybutyric acid (GHB) was first discovered as a naturally occurring substance in the brain. Since then it has been manufactured as a drug with a clinical application and has also developed a reputation as the illegal drug fantasy and as a date rape drug. Its physiological function is still unknown. Researchers identify ...

Mapping the Neural Circuitry of Autism

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When a single gene in the cerebellum of mice is deleted, it can cause key autistic-like symptoms, discover researchers. They also discovered that rapamycin, a commonly used immunosuppressant drug, prevented these symptoms. The deleted gene is associated with Tuberous Sclerosis Complex (TSC), a rare genetic condition. Since nearly 50 percent of all people with TSC develop autism, the researchers believe their findings will help us better understand the condition's ...

Rate of Community-Onset MRSA Infections Appears to Be on the Decline: Study

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According to a study in an analysis the rates of both community-onset and hospital-onset methicillin-resistant iStaphylococcus aureus/i (MRSA) bacteremia decreased from 2005 to 2010. The analysis included more than 9 million Department of Defense nonactive and active duty personnel and also found that the proportion of community-onset skin and soft tissue infections due to MRSA has more recently declined. The study can be found in the July 4 issue of iJAMA/i. "The ...

Abuse During Childhood may Contribute to Obesity in Adulthood: Research

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An investigation report research has made findings that may shed light on influences on obesity during adulthood. The investigation was conducted by investigators from Boston University School of Medicine (BUSM) and Boston University's Slone Epidemiology Center. The study appears in the journal iPediatrics/i and has found an association of severity of sexual and physical abuse during childhood and adolescence with obesity during adulthood. The findings were ...

Hamburger Title Retained By Competitive Eater from Canada

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On the eve of New York's iconic hot dog classic, a competitive eater clinched his fourth straight hamburger title in Washington. The winner is a one-time anorexic from Toronto turned world-class competitive eater. Peter Czerwinski, 24, ate 15 hamburgers in the space of 10 minutes at the Z-Burger Independence Burger Eating Championship to win a (Dollar) 1,000 prize plus a similar amount of gift cards for the local burger chain. "Right now, I feel full, but I'm ...

Hormone Preserving Insulin Production And Beta Cell Function In Diabetes, Found

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Protective, anti-diabetic functions for a hormone that, such as insulin, is secreted by the islet cells of the pancreas discover researchers at Duke University Medical Center. The new hormone was found to stimulate insulin secretion from rat and human islet cells and protect islet cells in the presence of toxic, cell-killing factors used in the study. The study, which was supported in part by JDRF, a global leader in type 1 diabetes research, appears in the July ...

Despite the Risks Pufferfish a Hit in Japan

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In Japan, people are are hospitalised every year after eating pufferfish and the result is sometimes fatal. Yet, despite these apparent dangers, strict rules on serving the toxic delicacy in Tokyo are to be relaxed. Aficionados say the tingle that the meat of the pufferfish leaves on your lips -- caused by the potent neurotoxin it contains -- is part of the appeal. Never mind that the numbness tetrodotoxin creates can progress to paralysis and breathing ...

Particle Consistent With Eagerly Awaited Higgs Boson Observed by CERN Experiments

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At a seminar held at CERN1 today as a curtain raiser to the year's major particle physics conference, ICHEP2012 in Melbourne, the ATLAS and CMS experiments presented their latest preliminary results in the search for the long sought Higgs particle. Both experiments observe a new particle in the mass region around 125-126 GeV. "We observe in our data clear signs of a new particle, at the level of 5 sigma, in the mass region around 126 GeV. The outstanding performance ...

Teenage Girl's Leg Chopped Off, Virgin Blood Offered to Deity

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A teenage girl's leg was chopped off and her blood offered to a deity by two female sorcerers in Bihar's Purnia district yesterday. Thirteen-year-old Babli Kumari had gone to the two women believing they would cure her ailing brother. The sorcerers offered gram laced with jaggery and drugs to the girl to eat. When the drugged girl fell unconscious, they took the help of a male aide and cut off her leg with a chopper. Babli's blood was then offered to a ...

Brazil Pollution Case Orders Shell, BASF To Pay (Dollar) 500 Million

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Oil giant Shell and chemical titan BASF have been ordered by a Brazilian judge to pay (Dollar) 500 million in compensation for countless ex-workers suing for damages in a suspected plant contamination case, a judicial source revealed. Labor judge Ines Correa Cerqueira from the town of Paulinia in Sao Paulo state ruled that the two foreign companies must deposit (Dollar) 500 million in a compensation fund pending the outcome of the class action lawsuit, according to the source who ...

Pathway To Cancer Cell Duplication Barred by Researchers

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Patients with leukemia at times relapse because standard chemotherapy loses out on killing the self-renewing leukemia initiating cells, often cited as cancer stem cells, suggests research. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease. One such type of cancer is called pediatric T cell acute lymphoblastic leukemia, or T-ALL, often found in children, who have few treatment options ...

(Dollar) 3bn Fine for GlaxoSmithKline In US

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US authorities fined GlaxoSmithKline with (Dollar) 3 billion by Monday over accusations that it marketed drugs for unauthorized uses, withheld safety data, and defrauded the government's Medicaid program. The Justice Department said GSK was fined over misbranding its drugs Paxil and Wellbutrin, and for holding back data while making unbacked claims for its diabetes drug Avandia. GSK pleaded guilty and agreed to the fines in what the department called the largest ...

Treatment Guidelines And Position Statements On Transgender Persons, Suggests APA Task Force

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Development of clinical practice guidelines for psychiatrists handling patients who are transgender is required suggests report from the American Psychiatric Association (APA) Task Force on Treatment of Gender Identity Disorder (GID). The report also encourages the development of position statements regarding the health care and civil rights of people who are gender variant or transitioning gender. The task force report is available online in Springer's journal iArchives ...

New Target In Fighting Bacterial Infections Offered by Innate Immune System Protein

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Potential new approach to overcome bacterial infections by targeting an innate immune system component in an attempt to invigorate the immune response identified by research led by St. Jude Children's Research Hospital scientists. In this study, researchers demonstrated that the primary function of one of the innate immune molecules is to suppress inflammation, which in turn dampens the immune response to infections and other threats. Investigators showed the protein ...

Regret Over Prostate Cancer Treatment Among 52 Percent of Men With Cardiovascular Disease

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52 per cent of prostate cancer patients with cardiovascular disease were more probable to regret their treatment choices than men who are not ailing with their heart or veins, states study published in the July issue of the urology journal iBJUI International/i. Research led by Harvard Medical School, USA, looked at 795 men with recurrent cancer in the Comprehensive Observational Multicenter Prostate Adenocarcinoma (COMPARE) registry. "Treatment ...

Pain Intensity Rises While Viewing Terrorist Attacks On TV: Ben-Gurion U. Researchers

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Media coverage of terrorist missile attacks for viewership amplifies pain levels in people already afflicted with chronic pain, states new study by Ben-Gurion University of the Negev (BGU) researchers. "Does War Hurt? Effects of Media Exposure After Missile Attacks on Chronic Pain," published in the online version of the IJournal of Clinical Psychology in Medical Settings, /Ishowed that exposure to the attacks through the media predicted an increase in pain ...

Shingles Vaccine may Not Increase Risk of Reactivating Shingles in People With Immune Disorders

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There is long-standing belief that the vaccine for shingles should not be given to patients taking biologics for auto-immune diseases such as rheumatoid arthritis. New research from the University of Alabama at Birmingham suggests shingles vaccine may be given to this population without increasing the risk of adverse reaction to the vaccine. The findings are published in the iJournal of the American Medical Association./i Shingles, or herpes zoster, is a reactivation ...

Role of DNA Methylation in Progression of Rheumatoid Arthritis

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Epigenetic changes due to DNA methylation alter genes in rheumatoid arthritis, say researchers. Their study is currently published in the online edition of the iAnnals of the Rheumatic Diseases/i. "Genomics has rapidly advanced our understanding of susceptibility and severity of rheumatoid arthritis," said Firestein. "While many genetic associations have been described in this disease, we also know that if one identical twin develops RA that the other ...

Girls Below Eight Years are Less Active Than Boys of the Same Age

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Researchers at the Newcastle University have revealed that children younger than eight years need to be targeted to combat the wide-spreading menace of childhood obesity. It is well known that childhood obesity has tripled in the past three decades with the increasing number of obese children. This sudden increase is due to the change in dietary habits and lifestyle behaviors. Obesity, especially in children, raises various health ...

Diabetes Drug Increases Bladder Cancer Risk

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Pioglitazone - a drug used to treat type 2 diabetes is linked to increased risk of bladder cancer, say researchers. People with type 2 diabetes are at risk of several types of cancer, including a 40% increased risk of bladder cancer, compared to people without diabetes. Previous studies have shown a higher incidence of bladder cancer in people taking pioglitazone, a type of thiazolidinedione. To determine whether there is a link between pioglitazone ...

Obesity, Larger Waist Size May Provide Protective Health Benefits for Heart Failure Patients

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Though slim waist and normal weight usually point to better health outcomes, in heart failure patients, high body mass index (BMI) and larger waist may provide protective health benefits according to a new UCLA study. Researchers found that in both men and women with advanced heart failure, obesity - as indicated by a high body mass index - and a higher waist circumference were factors that put them at significantly less risk for adverse outcomes. The ...

Study Finds Angry Teens may be Suffering from Intermittent Explosive Disorder

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Based on findings from a household survey of US teenagers, psychologists found one in 12 adolescents have such a short temper that they could be suffering from IED - intermittent explosive disorder. The condition is typically characterised by persistent and uncontrollable anger attacks. The study, based on a household survey of 10,148 young teenagers in the US, found that nearly two thirds had a history of anger attacks involving real or threatened violence. ...

Bird Flu Outbreak Reported in China

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More than 150,000 chickens have been culled following an outbreak of bird flu in China's remote northwestern region of Xinjiang, say officials. The outbreak of the H5N1 strain of avian flu initially killed 1,600 chickens and sickened about 5,500, the agriculture ministry said late Monday. In an effort to contain the disease, agricultural authorities quarantined the area and culled 156,439 chickens, according to the ministry. The outbreak ...

Research Finds Health Benefit of Parenthood - Parents Less Likely to Develop Colds

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Research exploring the health benefits of parenthood has found parents are less likely to develop colds than non parents. Being a parent can sometimes be challenging both physically and mentally. However knowledge of the actual effect parenthood has on health has been inconsistent at best, until now. New research led by Carnegie Mellon University's Sheldon Cohen and Rodlescia S. Sneed shows that being a parent influences health in a positive way. Published ...

Potential Combination Therapy for Breast Cancer Identified

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Researchers have identified an effective combination therapy for breast cancer cells. The findings, published in the July 2012 issue of iAnticancer Research/i, raise the possibility of using this type of combination therapy for different forms of breast cancer, including those that develop resistance to chemotherapy and other treatments. The study was led by researchers at the Boston University Cancer Center. Sibaji Sarkar, PhD, adjunct instructor of ...

Childhood Adversity Ups Depression Risk

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Early childhood adversity increases risk of depression and inflammation, finds study published in iBiological Psychiatry/i. They recruited a large group of female adolescents who were healthy, but at high risk for experiencing depression. The volunteers were then followed for 2 years, undergoing interviews and giving blood samples to measure their levels of C-reactive protein and interleukin-6, two types of inflammatory markers. Their exposure to childhood ...

First Over-the-counter HIV Home Testing Kit Approved in US

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The United States has authorized the first over-the-counter home testing kit for HIV, the virus that leads to acquired immune deficiency syndrome (AIDS), the Food and Drug Administration announced Tuesday. Under the testing procedure, the OraQuick In-Home HIV test kit will allow purchasers to collect an oral fluid sample by swabbing the upper and lower gums inside of their mouths, the Food and Drug Administration (FDA) announced. The sample is placed ...

Women Use IVF to Select Healthy Embryos

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Fertile women with a genetic predisposition to breast and ovarian cancer, with mutations of genes called BRCA1 and BRCA2 are now using IVF to select embryos without the genes to ensure their children are well protected from potentially trouble causing genes. The technique called as preimplantation genetic diagnosis (PGD) is quite expensive and is being used to select normal embryos. Nearly 10 couples had used the procedure for the breast and ovarian cancer genes ...

Genetic Connections Between Breast Size and Breast Cancer Identified

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A leading genetics company has discovered surprising genetic associations between breast size and breast cancer. These findings make the first concrete genetic link between breast size and breast cancer risks. These findings were made analyzing data from 16,175 female 23andMe customers of European ancestry, comparing their answers to survey questions including bra cup size and bra band size to genetic data at millions of SNPs. The analysis controlled for age, ...

H1N1 Flu Kills 11 People in Bolivia

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Health officials in Bolivia said Tuesday that at least 11 people in Bolivia have died from H1N1 flu in recent months, with most of the deaths occurring in just the past few weeks. Deputy Health Minister Martin Maturano said 873 cases had been reported across the country, and urged Bolivians to take preventive measures, such as eating well and frequently washing their hands. Bolivian authorities have not said whether the strain of the virus originated ...

Novel Drug Offers Hope Against Hookworm Infections

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A new drug candidate is showing promise as a cure for hookworm infections, say researchers from UCSF and Yale University. The drug candidate, known by the scientific name K11777, is under development at UCSF and is targeted to enter clinical trials in the next one to two years to treat Chagas disease, a potentially fatal parasitic disease common to Latin America. In the current study, researchers at the UCSF Center for Discovery and Innovation ...

Cholera Outbreak Kills Three in Cuba

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Cholera outbreak in eastern Cuba has killed three people, report sources. Health workers have identified 53 people infected with the illness in the coastal town of Manzanillo. In a statement published in the official newspaper Granma, Cuba's ministry of public health said in a statement that the three fatalities were elderly people aged 66, 70 and 95. Authorities said about a thousand people were receiving preventative medical treatment ...

Outcome of Patients Who Refuse Transfusion Following Cardiac Surgery Examined By Study

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According to a report, Jehovah's Witness patients who undergo cardiac surgery do not appear to be at increased risk for surgical complications or death. This is in comparison to those patients who undergo cardiac surgery and receive blood transfusion. The report was published online first by IArchives of Internal Medicine,/I a JAMA Network publication. Jehovah's Witness patients (Witnesses) hold beliefs that disallow blood product transfusion and encourage ...

Single Protein Promotes Resistance to Widely Used Anti-estrogen Drugs: Research

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Researchers have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women. The researchers are from Georgetown Lombardi Comprehensive Cancer Center. In the July 1 issue of iCancer Research/i, the scientists say glucose-regulated protein 78 (GRP78), activated as breast cells undergo stress induced by the agents tamoxifen and fulvestrant, turns off apoptosis, a ...

Round-the-clock Weddings Being Introduced By Britain

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Officials announced that couples in England will be able to get married at any time of night or day from October. Marriages in England and Wales are currently banned outside the hours of 8:00 am and 6:00 pm, under rules dating back to 1837. The change opens up the possibility of dawn ceremonies or midnight marriages at historic venues that are only open to the public during the day. The new rules will also apply to civil partnerships for ...

Revelation Of Secrets of Lung Cancer Drug Resistance at UCSF

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People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty. The uncertainty dawns around the fact that their tumors may initially shrink, it's not a question of whether their cancer will return-it's a question of when. And for far too many, it happens far too soon. Now, a team of researchers at the University of California, San Francisco's Helen Diller Family Comprehensive Cancer Center has discovered that a human protein called AXL ...

Parents Avoid Talking About Weight With Their Overweight Kids

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A study conducted by social enterprise Mend and the online community Netmums has pointed a key reason behind child obesity. Parents are hesitant to talk to their children about weight issues, worried if the discussion could affect the child psychologically. Parents did not want to broach the subject as they feared hurting the self esteem of the child which could possibly fuel eating disorders. Mr. Paul Sacher, Mend's co-founder and chief research and ...

Kid Should Not Be Taught Maths Or Physics On Thursdays

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Russia's chief sanitary doctor has said in a recommendation that schools should not teach difficult subjects like mathematics and physics to children on Thursdays because it was "the hardest day of the week." "Children have their own bio-rhythms and Thursday is the hardest day of the week," RIA Novosti quoted Gennady Onishchenko as telling the Ekho Moskvy radio station in an interview. "Therefore, it is not recommended to teach difficult subjects like ...

Taking Tailoring to the Masses Using Body Scanner

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Imagine a tailored suit helping you clinch that tricky deal at work or even getting a girl. What if it helps put a spring in your step. Well this could be possible if you believe a year-old Paris firm that is using a 3D body scanner to bring made-to-measure to the masses. "There is a whole psychological side to men's suits," said Francois Chambaud, co-founder of Paris store Les Nouveaux Ateliers. "Say you arrive at a meeting -- or your wedding -- in an ill-fitting ...

Possibility Of Creating Replacement Liver from Patient's Own Cells

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An Indian origin scientist and her team are hopeful that new advances in tissue engineering and regenerative medicine could one day make a replacement liver from a patient's own cells. It could also be an animal muscle tissue that could be cut into steaks without ever being inside a cow. Bioengineers can already make 2D structures out of many kinds of tissue, but one of the major roadblocks to making the jump to 3D is keeping the cells within large structures from ...

MPH Degree Program Offered in India By Johns Hopkins University

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Johns Hopkins Bloomberg School of Public Health will be offering a Master of Public Health (MPH) degree program in Jaipur, India. It will begin in fall 2012 and it is in collaboration with the Indian Institute of Health Management Research (IIHMR). The Jaipur-based MPH program is specifically intended for citizens and residents of India and low- and middle-income countries in the region. The program's focus will be on public health capacity building ...

NOAA Says Mermaids Don't Exist

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The National Oceanic and Atmospheric Administration (NOAA) recently posted a statement on their web site denying the existence of mermaids. NOAA enerally deals with environmental matters like tsunamis and hurricanes. In the post titled, "No Evidence of Aquatic Humanoids Has Ever Been Found," NOAA has a number of observations. Firstly, the belief in mermaids may have arisen at the very dawn of our species. Secondly, magical female figures ...