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** ALZHEIMER'S / DEMENTIA News **
Copper in diet linked to Alzheimer's disease
http://mnt.to/a/4gpr
New research suggests copper that enters the body at levels encountered in the average modern diet may be leading, eventually, to Alzheimer's disease - by reducing the body's ability to clear away toxic proteins in the brain, and also by encouraging the clumping of those proteins.
Dementia risk score for people with diabetes
http://mnt.to/a/4gpb
Scientists have created a simple scoring system that will allow clinicians to predict whether older people with type 2 diabetes are at risk of developing dementia, according to a study published in The Lancet Diabetes and Endocrinology.
New Risk Score Predicts 10-Year Dementia Risk for Type 2 Diabetes Patients
http://mnt.to/a/4gkN
Researchers at Kaiser Permanente and the University Medical Centre Utrecht in the Netherlands have created the first risk score that predicts the 10-year individualized dementia risk for patients with type 2 diabetes, as reported in the inaugural issue of Lancet Diabetes & Endocrinology.
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** ANXIETY / STRESS News **
A new biomarker for chronic stress: Hair Cortisol
http://mnt.to/a/4gpm
Cortisol is a well-known stress hormone and until recently, we have only been able to understand how stressed a person has been for about the past 20 minutes or the past day. Now, with about 100 strands of hair clipped from the scalp, we can get a biological indicator of stress over the past three months.
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** ARTHRITIS / RHEUMATOLOGY News **
Adding tofacitinib to treatment with DMARDs improves pain and function in patients with active RA
http://mnt.to/a/4gpy
Adding tofacitinib to treatment with disease-modifying anti-rheumatic drugs (DMARDs) may help improve symptoms in patients with active rheumatoid arthritis (RA). Nonbiologic DMARDs, including methotrexate, are commonly used to treat RA.
Joint symptoms in postmenopausal women not reduced by calcium plus vitamin D supplementation
http://mnt.to/a/4gnL
A team of investigators systematically analyzed the effect of calcium and vitamin D supplementation on joint symptoms in a rigorous and controlled study of postmenopausal women. They found that supplementation did not reduce the severity of joint symptoms reported by the participants.
Lateral wedge insoles not associated with improvement of knee pain in osteoarthritis
http://mnt.to/a/4gnp
Although a pooling of data from 12 studies showed a statistically significant association between use of lateral wedge insoles and lower pain in medial knee osteoarthritis, among trials comparing wedge insoles with neutral insoles, there was no significant or clinically important association between use of wedge insoles and reduction in knee pain, according to a study in the August 21 issue of JAMA.
----------------------------------------------
** AUTISM News **
Risk of autism in further children - study findings
http://mnt.to/a/4gph
A large population-based study from Denmark has followed siblings for the risk for autism spectrum disorders, finding different likelihoods depending on birth year, and also whether brothers or sisters were half- or full-siblings.
Different brain organization identified in autistic children who excel at math
http://mnt.to/a/4gnC
Children with autism and average IQs consistently demonstrated superior math skills compared with nonautistic children in the same IQ range, according to a study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.
----------------------------------------------
** BIOLOGY / BIOCHEMISTRY News **
A new biomarker for chronic stress: Hair Cortisol
http://mnt.to/a/4gpm
Cortisol is a well-known stress hormone and until recently, we have only been able to understand how stressed a person has been for about the past 20 minutes or the past day. Now, with about 100 strands of hair clipped from the scalp, we can get a biological indicator of stress over the past three months.
Instructions for planarian regeneration provided by muscle cells
http://mnt.to/a/4gnS
By studying the planarian flatworm, a master of regenerating missing tissue and repairing wounds, Whitehead Institute Member Peter Reddien and his lab have identified an unexpected source of position instruction: the muscle cells in the planarian body wall.
Discovery of cell memory mechanism
http://mnt.to/a/4gnM
The cells in our bodies can divide as often as once every 24 hours, creating a new, identical copy. DNA binding proteins called transcription factors are required for maintaining cell identity.
Research shows how females choose the 'right' sperm
http://mnt.to/a/4gnG
University of East Anglia scientists have revealed how females select the 'right' sperm to fertilize their eggs when faced with the risk of being fertilized by wrong sperm from a different species.
----------------------------------------------
** BONES / ORTHOPEDICS News **
Lateral wedge insoles not associated with improvement of knee pain in osteoarthritis
http://mnt.to/a/4gnp
Although a pooling of data from 12 studies showed a statistically significant association between use of lateral wedge insoles and lower pain in medial knee osteoarthritis, among trials comparing wedge insoles with neutral insoles, there was no significant or clinically important association between use of wedge insoles and reduction in knee pain, according to a study in the August 21 issue of JAMA.
----------------------------------------------
** BREAST CANCER News **
Anglia Ruskin experts want introduction of new treatment model for ductal carcinoma in situ (DCIS) patients
http://mnt.to/a/4gp9
Breast cancer specialists at Anglia Ruskin University are proposing the introduction of a new model to provide safer treatment for patients with ductal carcinoma in situ (DCIS), the most common form of non-invasive breast cancer.
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** CANCER / ONCOLOGY News **
Glioblastoma response to anti-angiogenesis therapy revealed by new MR analysis technique
http://mnt.to/a/4gnY
A new way of analyzing data acquired in MR imaging appears to be able to identify whether or not tumors are responding to anti-angiogenesis therapy, information that can help physicians determine the most appropriate treatments and discontinue ones that are ineffective.
Cancer-fighting immune activity boosted by dialing back Treg cell function in animal model
http://mnt.to/a/4gnX
By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy - harnessing the body's immune system to attack tumors.
Long-term side-effects in testicular cancer could be reduced by chemotherapy before radiotherapy
http://mnt.to/a/4gnH
Giving men with testicular cancer a single dose of chemotherapy alongside radiotherapy could improve the effectiveness of treatment and reduce the risk of long-term side-effects, a new study reports.
Twice as many people think cancer is a death sentence in the UK compared to the US
http://mnt.to/a/4gm8
The Lilly PACE initiative today launched the results of a survey of cancer patients, their carers and the general public around current perceptions of cancer care. The survey, conducted in six countries across the globe, showed that in the UK although the majority of people (73%)[1] are satisfied with recent progress in the fight against cancer, half of them (42%)1 still feel a diagnosis of cancer is a death sentence.
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** CARDIOVASCULAR / CARDIOLOGY News **
Eating fruit cut risk of abdominal aortic aneurysm in study
http://mnt.to/a/4gq3
Eating our daily quota of fruits and vegetables should be a no-brainer by now, as we have long heard of the health benefits accompanying a balanced diet. And now researchers in Sweden have discovered that eating more fruit could lower risks for an often-lethal form of aortic aneurysm.
Personalized drug dosing necessary for older heart patients
http://mnt.to/a/4gnF
Older heart patients present unique challenges for determining the optimal dosages of medications, so a new study from researchers at Duke Medicine offers some rare clarity about the use of drugs that are used to treat patients with heart attacks.
Higher urinary albumin excretion associated with increased risk of coronary heart disease among black adults
http://mnt.to/a/4gnn
In a large national study, higher levels of the urinary albumin-to-creatinine ratio was associated with greater risk of incident but not recurrent coronary heart disease in black individuals when compared with white individuals, according to a study in the August 21 issue of JAMA.
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** CHOLESTEROL News **
High cholesterol riskier for middle-aged men than women
http://mnt.to/a/4gnJ
High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.
----------------------------------------------
** CLINICAL TRIALS / DRUG TRIALS News **
New epidemiological study in malignant hyperthermia reinforces the effectiveness of Dantrium® in reducing fatal anaesthetic reaction
http://mnt.to/a/4gp7
For the first time, a new Canadian epidemiologic study reveals that a 15.5 per cent incidence of adverse anaesthetic reactions is triggered by succinylcholine alone. In line with previous findings, the study also further underlines that early recognition and prompt administration of dantrolene intravenous are critical for patient survival and reduction of complications.
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** CONFERENCES News **
7th Annual Optimizing Clinical Trials: Site Selection and Feasibility, 24-26 September 2013, Berlin
http://mnt.to/a/4gqd
Find out how to optimize Clinical TrialsClinical trials involve patients with specific health problems. Once the decision has been made by patients to participate in a clinical trial, it's important to minimize research delays and keep clinical trials moving forward.
3rd Annual Pharma Marketing Summit, 24-26 September 2013, Berlin
http://mnt.to/a/4gqc
Network with executives from Pharma Marketing under one roofBerlin, GE - Marketers from significant Pharma brands are going to discuss about increasing the power of marketing in the current business environment.
3rd Annual Pharma Commercial and SFE Summit, 24-26 September 2013, Berlin
http://mnt.to/a/4gq9
Discover how to optimize sales force effectiveness "We were born to succeed, not to fail" Henry David Thoreau3rd Annual Pharma Commercial and SFE Summit will exchange experience with the top experts from the pharma and biotech industry.
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** COPD News **
Link between viral infection, specialized lung cells and COPD
http://mnt.to/a/4gnR
Investigators at Washington University School of Medicine in St. Louis have described another link in the chain of events that connect acute viral infections to the development of chronic obstructive pulmonary disease (COPD).
----------------------------------------------
** DEPRESSION News **
Home-based interventions ease depression in elderly African Americans
http://mnt.to/a/4gpx
Home-based care interventions delivered by social workers can reduce depressive symptoms and enhance quality of life in older African Americans. Depression is common among older adults and African Americans are at greater risk than white persons for not receiving standard depression care or treatment.
----------------------------------------------
** DIABETES News **
Dementia risk score for people with diabetes
http://mnt.to/a/4gpb
Scientists have created a simple scoring system that will allow clinicians to predict whether older people with type 2 diabetes are at risk of developing dementia, according to a study published in The Lancet Diabetes and Endocrinology.
New Risk Score Predicts 10-Year Dementia Risk for Type 2 Diabetes Patients
http://mnt.to/a/4gkN
Researchers at Kaiser Permanente and the University Medical Centre Utrecht in the Netherlands have created the first risk score that predicts the 10-year individualized dementia risk for patients with type 2 diabetes, as reported in the inaugural issue of Lancet Diabetes & Endocrinology.
----------------------------------------------
** EYE HEALTH / BLINDNESS News **
Topical formulation identified for prolonged graft survival in corneal transplants
http://mnt.to/a/4gpn
Argos Therapeutics Inc., a biopharmaceutical company focused on the development and commercialization of therapies that modulate the immune system to treat cancer, infectious diseases, transplant rejection, autoimmune and inflammatory diseases, has announced the publication of key findings on its soluble recombinant human CD83 protein (sCD83) in cornea transplants.
Health Canada approves JETREA® for the treatment of symptomatic vitreomacular adhesion
http://mnt.to/a/4gpf
ThromboGenics NV (Euronext Brussels: THR), an integrated biopharmaceutical company focused on developing and commercializing innovative ophthalmic medicines, has announced that Health Canada has approved JETREA(R) (ocriplasmin) for the treatment of symptomatic vitreomacular adhesion (VMA).
Critical role discovered for the complement system in early macular degeneration
http://mnt.to/a/4gnP
In a study published on line in the journal Human Molecular Genetics, Drs. Donita Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School, along with their colleagues, reported the unexpected finding that in mice genetically engineered to have an inherited form of macular degeneration, turning off the animals' complement system, a part of the immune system, prevented the disease.
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** GASTROINTESTINAL / GASTROENTEROLOGY News **
Study examines genetic associations for gastrointestinal condition in infants
http://mnt.to/a/4gnq
Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study in the August 21 issue of JAMA.
----------------------------------------------
** GENETICS News **
Discovery of cell memory mechanism
http://mnt.to/a/4gnM
The cells in our bodies can divide as often as once every 24 hours, creating a new, identical copy. DNA binding proteins called transcription factors are required for maintaining cell identity.
TACC supercomputers help researchers understand DNA bending and repair mechanisms
http://mnt.to/a/4gnB
Results from computer simulations show that it is energetically less expensive to bend mismatch-containing, defective DNA (G:T, C:C, C:T, G:A, G:G, T:T, A:A, A+:C) vs. non-defective DNA (containing A:T or G:C base pairs).
Study examines genetic associations for gastrointestinal condition in infants
http://mnt.to/a/4gnq
Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study in the August 21 issue of JAMA.
----------------------------------------------
** HEART DISEASE News **
High cholesterol riskier for middle-aged men than women
http://mnt.to/a/4gnJ
High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.
Personalized drug dosing necessary for older heart patients
http://mnt.to/a/4gnF
Older heart patients present unique challenges for determining the optimal dosages of medications, so a new study from researchers at Duke Medicine offers some rare clarity about the use of drugs that are used to treat patients with heart attacks.
----------------------------------------------
** HIV / AIDS News **
Exploring trends in perinatally infected HIV patients now approaching adulthood
http://mnt.to/a/4gnD
The advent of antiretroviral therapy (ART) has transformed HIV from a death sentence into a chronic disease. In one of the largest studies of perinatally infected HIV (PHIV) patients to date, Agwu, et al, found that the proportion of patients on ART has increased and rates of viremia and advanced immunosuppression have decreased.
----------------------------------------------
** HYPERTENSION News **
Implementation of multifaceted hypertension quality improvement program associated with increase in blood pressure control rates
http://mnt.to/a/4gnm
Implementation of a large-scale hypertension program that included evidence-based guidelines and development and sharing of performance metrics was associated with a near-doubling of hypertension control between 2001 and 2009, compared to only modest improvements in state and national control rates, according to a study in the August 21 issue of JAMA.
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** IMMUNE SYSTEM / VACCINES News **
Bypassing immune rejection in stem-cell-based therapies
http://mnt.to/a/4gp8
The scientific community has held tremendous hope for the eventual emergence of stem cell transplantation as a broadly applicable and highly effective therapeutic strategy. However, the realization of this hope has been plagued by the indomitable immune response to the transplantation of human embryonic stem cell (hESC) derivatives, which prevents the engraftment and long-term survival necessary for functional recovery or preservation of the host tissue.
Cancer-fighting immune activity boosted by dialing back Treg cell function in animal model
http://mnt.to/a/4gnX
By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy - harnessing the body's immune system to attack tumors.
----------------------------------------------
** INFECTIOUS DISEASES / BACTERIA / VIRUSES News **
Link between viral infection, specialized lung cells and COPD
http://mnt.to/a/4gnR
Investigators at Washington University School of Medicine in St. Louis have described another link in the chain of events that connect acute viral infections to the development of chronic obstructive pulmonary disease (COPD).
----------------------------------------------
** LIVER DISEASE / HEPATITIS News **
Caffeinated drinks may be good for the liver
http://mnt.to/a/4gp5
Researchers have discovered that an increased caffeine intake may reduce the risk of non-alcoholic fatty liver disease, according to a study published in the journal Hepatology.A team from the Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine used cell culture and mice as models for the effects of caffeine on the liver disease.
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** LYMPHOMA / LEUKEMIA / MYELOMA News **
Treatment-resistant lymphomas 'reprogrammed' to respond to cancer drugs
http://mnt.to/a/4gnK
A phase I clinical trial showed diffuse, large B-cell lymphomas (DLBCLs) resistant to chemotherapy can be reprogrammed to respond to treatment using the drug azacitidine, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.
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** MEN'S HEALTH News **
High cholesterol riskier for middle-aged men than women
http://mnt.to/a/4gnJ
High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.
----------------------------------------------
** MENOPAUSE News **
Joint symptoms in postmenopausal women not reduced by calcium plus vitamin D supplementation
http://mnt.to/a/4gnL
A team of investigators systematically analyzed the effect of calcium and vitamin D supplementation on joint symptoms in a rigorous and controlled study of postmenopausal women. They found that supplementation did not reduce the severity of joint symptoms reported by the participants.
----------------------------------------------
** MENTAL HEALTH News **
Junk food in pregnancy linked to childhood mental disorders
http://mnt.to/a/4gpY
During pregnancy, it can be hard not to give in to those cravings for unhealthy foods. But researchers have found that mothers who eat junk food while pregnant are more likely to have children with mental health problems.
----------------------------------------------
** MRI / PET / ULTRASOUND News **
Glioblastoma response to anti-angiogenesis therapy revealed by new MR analysis technique
http://mnt.to/a/4gnY
A new way of analyzing data acquired in MR imaging appears to be able to identify whether or not tumors are responding to anti-angiogenesis therapy, information that can help physicians determine the most appropriate treatments and discontinue ones that are ineffective.
----------------------------------------------
** NEUROLOGY / NEUROSCIENCE News **
Copper in diet linked to Alzheimer's disease
http://mnt.to/a/4gpr
New research suggests copper that enters the body at levels encountered in the average modern diet may be leading, eventually, to Alzheimer's disease - by reducing the body's ability to clear away toxic proteins in the brain, and also by encouraging the clumping of those proteins.
Anti-wrinkle ingredient: 'preventive potential' in Parkinson's disease
http://mnt.to/a/4gpd
Scientists say they have discovered that a chemical used in anti-wrinkle cream has potential to prevent early-onset Parkinson's disease.The findings could be used to develop drugs to prevent the cell death seen in the brains of people with Parkinson's disease, say the researchers from the University of California in San Francisco (UCSF).
Dementia risk score for people with diabetes
http://mnt.to/a/4gpb
Scientists have created a simple scoring system that will allow clinicians to predict whether older people with type 2 diabetes are at risk of developing dementia, according to a study published in The Lancet Diabetes and Endocrinology.
Glioblastoma response to anti-angiogenesis therapy revealed by new MR analysis technique
http://mnt.to/a/4gnY
A new way of analyzing data acquired in MR imaging appears to be able to identify whether or not tumors are responding to anti-angiogenesis therapy, information that can help physicians determine the most appropriate treatments and discontinue ones that are ineffective.
----------------------------------------------
** NUTRITION / DIET News **
Restaurants 'should help tackle obesity' through apps and websites
http://mnt.to/a/4gq5
Researchers have suggested that restaurants could help tackle obesity by expanding and improving calorie listings and "healthy eating" options on their websites and mobile apps, encouraging customers to self-monitor what they eat.
Eating fruit cut risk of abdominal aortic aneurysm in study
http://mnt.to/a/4gq3
Eating our daily quota of fruits and vegetables should be a no-brainer by now, as we have long heard of the health benefits accompanying a balanced diet. And now researchers in Sweden have discovered that eating more fruit could lower risks for an often-lethal form of aortic aneurysm.
Junk food in pregnancy linked to childhood mental disorders
http://mnt.to/a/4gpY
During pregnancy, it can be hard not to give in to those cravings for unhealthy foods. But researchers have found that mothers who eat junk food while pregnant are more likely to have children with mental health problems.
Caffeinated drinks may be good for the liver
http://mnt.to/a/4gp5
Researchers have discovered that an increased caffeine intake may reduce the risk of non-alcoholic fatty liver disease, according to a study published in the journal Hepatology.A team from the Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine used cell culture and mice as models for the effects of caffeine on the liver disease.
Joint symptoms in postmenopausal women not reduced by calcium plus vitamin D supplementation
http://mnt.to/a/4gnL
A team of investigators systematically analyzed the effect of calcium and vitamin D supplementation on joint symptoms in a rigorous and controlled study of postmenopausal women. They found that supplementation did not reduce the severity of joint symptoms reported by the participants.
----------------------------------------------
** OBESITY / WEIGHT LOSS / FITNESS News **
Restaurants 'should help tackle obesity' through apps and websites
http://mnt.to/a/4gq5
Researchers have suggested that restaurants could help tackle obesity by expanding and improving calorie listings and "healthy eating" options on their websites and mobile apps, encouraging customers to self-monitor what they eat.
----------------------------------------------
** PAIN / ANESTHETICS News **
New epidemiological study in malignant hyperthermia reinforces the effectiveness of Dantrium® in reducing fatal anaesthetic reaction
http://mnt.to/a/4gp7
For the first time, a new Canadian epidemiologic study reveals that a 15.5 per cent incidence of adverse anaesthetic reactions is triggered by succinylcholine alone. In line with previous findings, the study also further underlines that early recognition and prompt administration of dantrolene intravenous are critical for patient survival and reduction of complications.
----------------------------------------------
** PARKINSON'S DISEASE News **
Anti-wrinkle ingredient: 'preventive potential' in Parkinson's disease
http://mnt.to/a/4gpd
Scientists say they have discovered that a chemical used in anti-wrinkle cream has potential to prevent early-onset Parkinson's disease.The findings could be used to develop drugs to prevent the cell death seen in the brains of people with Parkinson's disease, say the researchers from the University of California in San Francisco (UCSF).
Study shows potential for new treatment strategy with effects of Parkinson's-disease mutation reversed in cells
http://mnt.to/a/4gnx
UC San Francisco scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson's disease.
----------------------------------------------
** PEDIATRICS / CHILDREN'S HEALTH News **
Risk of autism in further children - study findings
http://mnt.to/a/4gph
A large population-based study from Denmark has followed siblings for the risk for autism spectrum disorders, finding different likelihoods depending on birth year, and also whether brothers or sisters were half- or full-siblings.
The will to win forms at the age of four
http://mnt.to/a/4gnQ
New research suggests children don't understand competitive behaviour until around the age of four.A team of researchers from the University of Warwick and University of Salzburg found most children under 4 did not have a developed understanding of other people's perspectives - specifically, of the fact that what someone intentionally does depends on their take on the situation.
Exploring trends in perinatally infected HIV patients now approaching adulthood
http://mnt.to/a/4gnD
The advent of antiretroviral therapy (ART) has transformed HIV from a death sentence into a chronic disease. In one of the largest studies of perinatally infected HIV (PHIV) patients to date, Agwu, et al, found that the proportion of patients on ART has increased and rates of viremia and advanced immunosuppression have decreased.
Study examines genetic associations for gastrointestinal condition in infants
http://mnt.to/a/4gnq
Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study in the August 21 issue of JAMA.
----------------------------------------------
** PHARMA INDUSTRY / BIOTECH INDUSTRY News **
Metal-catalyzed cross-couplings of carbon bonds could enable creation of libraries of drug candidates to accelerate drug discovery
http://mnt.to/a/4gnN
James Bond had his reasons for ordering his martinis "shaken, not stirred." Similarly, drug manufacturers need to make sure the molecules in a new drug are arranged in an exact manner, lest there be dire consequences.
Chemical engineers find that arrays of carbon nanotubes can detect flaws in drugs and help improve production
http://mnt.to/a/4gny
MIT chemical engineers have discovered that arrays of billions of nanoscale sensors have unique properties that could help pharmaceutical companies produce drugs - especially those based on antibodies - more safely and efficiently.
----------------------------------------------
** PREGNANCY / OBSTETRICS News **
Junk food in pregnancy linked to childhood mental disorders
http://mnt.to/a/4gpY
During pregnancy, it can be hard not to give in to those cravings for unhealthy foods. But researchers have found that mothers who eat junk food while pregnant are more likely to have children with mental health problems.
Research shows how females choose the 'right' sperm
http://mnt.to/a/4gnG
University of East Anglia scientists have revealed how females select the 'right' sperm to fertilize their eggs when faced with the risk of being fertilized by wrong sperm from a different species.
Exploring trends in perinatally infected HIV patients now approaching adulthood
http://mnt.to/a/4gnD
The advent of antiretroviral therapy (ART) has transformed HIV from a death sentence into a chronic disease. In one of the largest studies of perinatally infected HIV (PHIV) patients to date, Agwu, et al, found that the proportion of patients on ART has increased and rates of viremia and advanced immunosuppression have decreased.
----------------------------------------------
** PREVENTIVE MEDICINE News **
Sensor attached to a construction worker's helmet can detect the onset of carbon monoxide poisoning
http://mnt.to/a/4gnw
Research calling for the use of a wearable computing system installed in a helmet to protect construction workers from carbon monoxide poisoning, a serious lethal threat in this industry, has garnered the Virginia Tech investigators a Best Paper Award from a prestigious scientific and engineering community.
----------------------------------------------
** PRIMARY CARE / GENERAL PRACTICE News **
Longer waiting times for GP appointments predicted as concerned GPs raise fears about the impact of cuts for patient care, UK
http://mnt.to/a/4gpg
Over 70% of GPs are forecasting longer waiting times for GP appointments within the next two years - as nearly half (47%) reveal that they have cut back on the range of services they provide for their patients.
----------------------------------------------
** PSYCHOLOGY / PSYCHIATRY News **
A new biomarker for chronic stress: Hair Cortisol
http://mnt.to/a/4gpm
Cortisol is a well-known stress hormone and until recently, we have only been able to understand how stressed a person has been for about the past 20 minutes or the past day. Now, with about 100 strands of hair clipped from the scalp, we can get a biological indicator of stress over the past three months.
The will to win forms at the age of four
http://mnt.to/a/4gnQ
New research suggests children don't understand competitive behaviour until around the age of four.A team of researchers from the University of Warwick and University of Salzburg found most children under 4 did not have a developed understanding of other people's perspectives - specifically, of the fact that what someone intentionally does depends on their take on the situation.
Different brain organization identified in autistic children who excel at math
http://mnt.to/a/4gnC
Children with autism and average IQs consistently demonstrated superior math skills compared with nonautistic children in the same IQ range, according to a study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.
----------------------------------------------
** PUBLIC HEALTH News **
Longer waiting times for GP appointments predicted as concerned GPs raise fears about the impact of cuts for patient care, UK
http://mnt.to/a/4gpg
Over 70% of GPs are forecasting longer waiting times for GP appointments within the next two years - as nearly half (47%) reveal that they have cut back on the range of services they provide for their patients.
A way for China to resolve its 'immigration' dilemma
http://mnt.to/a/4gnT
University of Washington geographer Kam Wing Chan is in China this week, explaining how that country can dismantle its 55-year-old system that limits rural laborers from moving to and settling in cities and qualifying for basic social benefits.
Sensor attached to a construction worker's helmet can detect the onset of carbon monoxide poisoning
http://mnt.to/a/4gnw
Research calling for the use of a wearable computing system installed in a helmet to protect construction workers from carbon monoxide poisoning, a serious lethal threat in this industry, has garnered the Virginia Tech investigators a Best Paper Award from a prestigious scientific and engineering community.
----------------------------------------------
** RADIOLOGY / NUCLEAR MEDICINE News **
Long-term side-effects in testicular cancer could be reduced by chemotherapy before radiotherapy
http://mnt.to/a/4gnH
Giving men with testicular cancer a single dose of chemotherapy alongside radiotherapy could improve the effectiveness of treatment and reduce the risk of long-term side-effects, a new study reports.
----------------------------------------------
** REGULATORY AFFAIRS / DRUG APPROVALS News **
Health Canada approves JETREA® for the treatment of symptomatic vitreomacular adhesion
http://mnt.to/a/4gpf
ThromboGenics NV (Euronext Brussels: THR), an integrated biopharmaceutical company focused on developing and commercializing innovative ophthalmic medicines, has announced that Health Canada has approved JETREA(R) (ocriplasmin) for the treatment of symptomatic vitreomacular adhesion (VMA).
----------------------------------------------
** RESPIRATORY / ASTHMA News **
Singing exercises reduce snoring
http://mnt.to/a/4gpq
Are you - or your partner - a chronic snorer? Joining a choir or taking singing lessons could help. A UK study found that a program of vocal exercises designed by a singing teacher helped reduce snoring.
----------------------------------------------
** SENIORS / AGING News **
Home-based interventions ease depression in elderly African Americans
http://mnt.to/a/4gpx
Home-based care interventions delivered by social workers can reduce depressive symptoms and enhance quality of life in older African Americans. Depression is common among older adults and African Americans are at greater risk than white persons for not receiving standard depression care or treatment.
Anti-wrinkle ingredient: 'preventive potential' in Parkinson's disease
http://mnt.to/a/4gpd
Scientists say they have discovered that a chemical used in anti-wrinkle cream has potential to prevent early-onset Parkinson's disease.The findings could be used to develop drugs to prevent the cell death seen in the brains of people with Parkinson's disease, say the researchers from the University of California in San Francisco (UCSF).
Critical role discovered for the complement system in early macular degeneration
http://mnt.to/a/4gnP
In a study published on line in the journal Human Molecular Genetics, Drs. Donita Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School, along with their colleagues, reported the unexpected finding that in mice genetically engineered to have an inherited form of macular degeneration, turning off the animals' complement system, a part of the immune system, prevented the disease.
Personalized drug dosing necessary for older heart patients
http://mnt.to/a/4gnF
Older heart patients present unique challenges for determining the optimal dosages of medications, so a new study from researchers at Duke Medicine offers some rare clarity about the use of drugs that are used to treat patients with heart attacks.
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** SLEEP / SLEEP DISORDERS / INSOMNIA News **
Singing exercises reduce snoring
http://mnt.to/a/4gpq
Are you - or your partner - a chronic snorer? Joining a choir or taking singing lessons could help. A UK study found that a program of vocal exercises designed by a singing teacher helped reduce snoring.
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** STEM CELL RESEARCH News **
Bypassing immune rejection in stem-cell-based therapies
http://mnt.to/a/4gp8
The scientific community has held tremendous hope for the eventual emergence of stem cell transplantation as a broadly applicable and highly effective therapeutic strategy. However, the realization of this hope has been plagued by the indomitable immune response to the transplantation of human embryonic stem cell (hESC) derivatives, which prevents the engraftment and long-term survival necessary for functional recovery or preservation of the host tissue.
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** TRANSPLANTS / ORGAN DONATIONS News **
Topical formulation identified for prolonged graft survival in corneal transplants
http://mnt.to/a/4gpn
Argos Therapeutics Inc., a biopharmaceutical company focused on the development and commercialization of therapies that modulate the immune system to treat cancer, infectious diseases, transplant rejection, autoimmune and inflammatory diseases, has announced the publication of key findings on its soluble recombinant human CD83 protein (sCD83) in cornea transplants.
Bypassing immune rejection in stem-cell-based therapies
http://mnt.to/a/4gp8
The scientific community has held tremendous hope for the eventual emergence of stem cell transplantation as a broadly applicable and highly effective therapeutic strategy. However, the realization of this hope has been plagued by the indomitable immune response to the transplantation of human embryonic stem cell (hESC) derivatives, which prevents the engraftment and long-term survival necessary for functional recovery or preservation of the host tissue.
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** UROLOGY / NEPHROLOGY News **
Too-low diastolic blood pressure can be deadly for CKD patients
http://mnt.to/a/4gps
Having too-low diastolic blood pressure (DBP) may be deadly for patients with chronic kidney disease (CKD). Blood pressure (BP) recommendations are stricter for patients with CKD than for the general population and focus on lowering actual BP (the measurement of both systolic BP [SBP] and DBP) without consideration for achieving a DBP that is too low.
Higher urinary albumin excretion associated with increased risk of coronary heart disease among black adults
http://mnt.to/a/4gnn
In a large national study, higher levels of the urinary albumin-to-creatinine ratio was associated with greater risk of incident but not recurrent coronary heart disease in black individuals when compared with white individuals, according to a study in the August 21 issue of JAMA.
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** WATER - AIR QUALITY / AGRICULTURE News **
Copper in diet linked to Alzheimer's disease
http://mnt.to/a/4gpr
New research suggests copper that enters the body at levels encountered in the average modern diet may be leading, eventually, to Alzheimer's disease - by reducing the body's ability to clear away toxic proteins in the brain, and also by encouraging the clumping of those proteins.
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