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Scientists Investigate Truth Behind the Relapse of Chronic Lymphocytic Leukemia

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Chronic lymphocytic leukemia (CLL) is the most frequent type of cancer affecting adults in Western countries. It usually occurs in older patients, does not show any symptoms for a long time and is often discovered only by accident. Despite treatment, relapses frequently occur. The immunologists Dr. Kristina Heinig and Dr. Uta Hopken (Max Delbruck Center for Molecular Medicine, MDC, Berlin-Buch) and the hematologist Dr. Armin Rehm (MDC and Charite; - Universitatsmedizin Berlin) ...

Entire Family to be Jailed If the Traditional Cleansing the Dead Ritual Continues in Sierra Leone

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On Friday, the Sierra Leone government warned that it would quarantine and jail the entire family if Ebola victims who appeared to have been washed after death were discovered in their homes. The tradition of cleansing the dead before burials, remains a major factor in the spread of the highly infectious virus, the government said, despite numerous appeals for Sierra Leoneans to refrain from the practice. "When the family calls (the burial hotline) and ...

Neural Network to Offer a Likely Diagnosis Using Digital Analysis of Patient's Tongue Image

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The human tongue can help the physician offer a diagnosis even though it may betray signs of illness, which combined with other symptoms such as a cough, fever, presence of jaundice, headache or bowel habits. For people in remote areas who do not have ready access to a physician, a new diagnostic system is reported in the iInternational Journal of Bio-medical Engineering and Technology/i that works to combine the soft inputs of described symptoms with a digital analysis ...

Campus Emergencies Call for Better Communications With Students

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In recent years, due to increase emergencies at educational establishments, the campus officials are beginning to recognize that better communications with their students are now needed. Writing in the iInternational Journal of Business Information Systems/i, US researchers describe how social networking sites might be exploited when an emergency situation arises to help safeguard students as well as keeping those not directly involved in the situation informed of events. ...

Scientists Study the Role of Cancer Cells and Some Fibroblasts in the Breakage of Cellular Membrane

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Though a carcinoma "in situ" means a cancer in place, it often does not keep its place. Standing between a cancer cell in situ and the surrounding tissue of fibroblasts and extra-cellular matrix is the basement membrane, a thin sheet of fibers that normally cradles the cells above it. The basement membrane is also the frontline physical barrier that keeps primary tumors from spreading into the matrix below. Perforating the basement membrane is a cancer cell's first move toward ...

Scientists Study Blood Brain Barrier Function in Pediatric Neurological Diseases

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The blood brain barrier (BBB) in the human brain is a very important aspect in human physiology. The human BBB separates circulating blood from the central nervous system, thus protecting the brain from many infections and toxins. But the BBB also blocks the passage of many potentially useful drugs to the brain and it has long stymied scientists who want to learn more about this vital tissue because of the lack of realistic non-human lab models. Even less is known ...

Recent Studies Shows Fine Tuning Cell Surroundings can Improve Leukemia's Response to Chemotherapy

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A study according to two Harvard bioengineers, has shown that cancer responds to the physical surroundings of bone marrow cells where human myeloid leukemias arise and where stiffness in the surrounding extracellular matrix (ECM) can predict how cancer subtypes react to chemotherapy. Correcting for the matrix effect could give oncologists a new tool for matching drugs to patients, the researchers say. In work to be presented at the ASCB/IFCB meeting in Philadelphia, ...

New Study Suggests the Role of Actin in Cell Nucleus Stability

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A paper published in iNature Cell Biologyi by Princeton bio engineers Marina Feric and Cliff Brangwynne, has changed the long term traditional explanation that the cells are the perfect microscopic size because if they were any bigger it would be difficult to get enough nutrients and energy to support them. The researchers studied the mechanics of the cell nucleus using eggs from the African clawed frog, Xenopus laevis. As cells go, Xenopus eggs are enormous. ...

Freedom Probe by U.S Makes China Defend Overseas Confucius Centers

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On Friday, one day after a US congressman called for a probe into the language and cultural centers over concerns that they violate academic freedom, China defended its overseas Confucius Institutes. The row over the Beijing-backed centers, which number nearly 100 in the US, mostly on the campuses of publicly-funded state universities, comes after a number of US, Canadian and other schools publicly cut ties with them. Chinese foreign ministry spokeswoman ...

Art Basel Show Transforms Miami Beach into an Art Hub

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As part of the prestigious Art Basel show, the US city of Miami Beach transformed into a hub of modern and contemporary art on Thursday. Organizers expect tens of thousands of expert art collectors and curators as well as casual shoppers and tourists to descend on the convention center in Miami Beach. The southern city adjacent to Miami has been the primary US host of the art show that originated in Switzerland. A thousand artists, representing ...

Americans Prefer Viewing Videos Online Rather Than on TV Sets

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A new study has revealed that online video streaming went up by 60 percent every year, while traditional television viewing fell down by four percent, in the United States. The Verge reported that according to Nielsen viewing figures, an average American watched approximately 11 hours of streaming video in the last month as compared to 7 hours a month a year ago. TV viewing was 141 hours a month as opposed to 147 hours a month in the last year. The emerging ...

Orange Juice Ten Times Healthier Than Currently Thought of

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The antioxidant activity of orange juice and juices from other citrus fruits is undervalued, suggests a new technique developed by researchers from the University of Granada. Current techniques involve analyzing only the antioxidant capacities of those substances that can potentially be absorbed in the small intestine- the liquid fraction of what we eat, and not measuring the antioxidant activity of the solid fraction (the fiber), whilst assuming that it is ...

Obesity Decreases Life Expectancy by 8 Years

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Obesity can decrease life expectancy by up to 8 years and lead to premature development of heart disease and diabetes, according to researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University. Researchers used data from almost 4,000 individuals from the National Health and Nutrition Examination Survey (from 2003 to 2010) to develop a model that estimates the annual risk of diabetes and cardiovascular disease in ...

Water Used to Process Raw Coffee Beans can Fuel Electric Generators

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Coffee farmers in Central American are using water used to process raw coffee beans to fuel electric generators by extracting the methane gas from it. The biogas generators are being fueled by these coffee byproducts that used to pollute local rivers. The fermentation of the coffee tree's berries leads to the production of methane gas which is highly polluting and a leading contributor to global warming. This pilot project is being carried out at 19 ...

Light Switchable Proteins Used to Observe Protein-protein Interactions in Live Cells

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Peng Xia and Xuebiao Yao of the Hefei National Laboratory for Physical Sciences at the Nanoscale and University of Science and Technology of China, and their colleagues have managed to visualize protein interactions at nanometer spatial resolution in live cells. The study is published in Molecular Biology of the Cell (MBoC) and will also presented at the 2014 ASCB/IFCB meeting in Philadelphia on December 8 at 1:30 pm in the ASCB Learning Center. To move around ...

Picasso Silver Plate Stolen from Art Basel Festival in Miami

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A silver plate crafted by Pablo Picasso, valued at (Dollar) 85,000, was stolen in Miami from the Art Basel festival, one of the world's premier art festivals. Amsterdam-based Leslie Smith Gallery owned the Picasso work. The 1956 work, 'Visage aux mains' is one in a series of 20 silver plates by the famous Spanish artist. The 16.5-inch (40-centimetre) plate features a rudimentary face and hands. Owner of the Leslie Smith Gallery, David Smith, said, "I've been ...

Rescuing the Golgi Puts Brakes on Alzheimer's Progression

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The progression of Alzheimer's disease (AD) can be arrested by rescuing the Golgi apparatus, the part of the cell involved in packaging and sorting protein cargo. The study was carried out by researchers Yanzhuang Wang, Gunjan Joshi, and colleagues at the University of Michigan, Ann Arbor. In order to uncover the mechanism damaging the Golgi, they used a transgenic mouse and tissue culture models of AD to look at what was happening inside the brain. AD ...

Star-Gazing Tourists Flock to Africa's Darkest Place for a Celestial Safari

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The Namib desert is one of a number of remote "Dark Sky Reserves" drawing in stargazers for a celestial safari. In the cool night air, an urbane Austrian tourist climbs rocky steps behind a chic hotel lodge and peers into a matt-black metal cylinder containing a spine of mirrors and lenses that reveal the universe. "My mum wanted to set him on fire yesterday when he said, 'We are looking ten million years in the past!'" he joked, pointing at the resident ...

'Alzheimer's in a Dish' Model Has a New Candidate

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The search for a living laboratory model of human neurons in the grip of Alzheimer's disease (AD) --"Alzheimer's in a dish"-- has a new candidate. In work presented at the ASCB/IFCB meeting in Philadelphia, Hakan Toresson and colleagues at Lund University in Sweden report success in creating induced neurons that model Alzheimer's by starting with fibroblasts taken from skin biopsies. The differentiated cells express a full range of normal neuronal markers. Significantly, ...

Vietnamese Cosmetic Surgeon Jailed for Dumping Patient's Body in River

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A Vietnamese court sentenced a cosmetic surgeon to 19 years in jail for throwing the body of a patient into a river who died during a botched operation. Le Thi Thanh Huyen, 37, died in October 2013 after undergoing liposuction and a breast augmentation operation at the private Cat Tuong Clinic in Hanoi, despite efforts by the centre's staff to revive her. Police said doctor Nguyen Manh Tuong dumped her body in the Vietnamese capital's main river, with ...

Vatican Finds Hundreds of Millions of Euros During an Overhaul of the System

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During an overhaul of the system aimed at transforming the once-murky institution into a paradigm of transparency, the Vatican has found hundreds of millions of euros. "We have discovered that the (Vatican's financial) situation is much healthier than it seemed," the pope's economy czar, Australian cardinal George Pell, told Britain's Catholic Herald. "Some hundreds of millions of euros were tucked away in particular sectional accounts and did not appear ...

The Intestinal Immune System Controls the Body Weight: Research

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UCL researchers (Louvain Drug Research Institute) identified an unsuspected mechanism impacting the development of obesity and diabetes type 2 after following a diet with a high dose of fat nutrition. The team of Professor Patrice D. Cani - in direct collaboration with two French teams, a Swedish expert as well as other UCL-researchers (LDRI and Ludwig Institute) - made an important discovery related to the essential role of the intestinal immune system regarding ...

New Drug Found Effective Against Leukaemia

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A new study has found a new treatment approach that could offer hope to patients with the aggressive blood cancer acute myeloid leukaemia (AML). The study conducted at QIMR Berghofer Medical Research Institute also found that imetelstat delayed or prevented relapse of AML following chemotherapy. Dr Steven Lane asserted that they tested the drug imetelstat against human leukaemia models and found that it killed or impaired progression of the disease. ...

Loss of Y Chromosome Behind Smokers' Increased Cancer Risk: Study

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An association between smoking and loss of the Y chromosome in blood cells that increases the risk of developing cancer in males, reveals a new study. Lars Forsberg, researcher at the Department of Immunology, Genetics and Pathology, Uppsala University, and responsible for the study, said that they have now tested if there were any lifestyle- or clinical factors that could be linked to loss of the Y chromosome. Out of a large number of factors that were studied, ...

Poisonous Mushrooms may Help Tackle Deadly Diseases: Study

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Scientists have discovered that poisonous mushrooms could help batting deadly diseases. According to the Michigan State University scientists, toxic fungi contains an enzyme that is the key to its lethal potency. The results reveal the enzyme's ability to create the mushroom's molecules that harbor missile-like proficiency in attacking and annihilating a single vulnerable target in the human liver. The team revealed how the enzyme contributes to the ...

Improving Basic Medical Care can Help Tackle Ebola Menace

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Researchers have suggested that the number of Ebola can be tackled if the basic medical care is improved and followed properly. The widespread misconception that there were no proven treatments for Ebola virus disease has meant that simple treatments, especially intravenous fluids and electrolytes, which could reduce the number of deaths caused by the virus, have been neglected. According to Dr Ian Roberts from the London School of Hygiene and Tropical ...

Kerala's Hospital Ties-Up With Paris-Based Organization to Save Children With Heart Ailments

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The Heart Fund has tied up with Amrita Institute of Medical Sciences (AIMS), Kochi to provide free life-saving open-heart surgeries and endovascular treatments to poor in India. The Heart Fund is a Paris-based international charity organization. So far, 20 children have been benefitted through this collaborative mission. "AIMS is the first and only medical facility in India to have been selected for this mission for its proven track-record in cardiovascular ...

Disney Unveils Learning Apps

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Disney unveiled a portfolio of learning apps for children, harnessing the appeal of iconic characters such as Mickey Mouse, Donald Duck and Goofy to subjects like math, science, creative arts and languages. The entertainment giant said its "Disney Imagicademy" aims to expose three to eight-year-old children to core educational concepts via a curriculum developed in conjunction with academic and education experts. The company said more than 30 app-based ...

A Virtual Stroll In Rome Through the Ghetto

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Rome has a new walk on its historical tourism circuit. It is a virtual stroll through the streets of the ghetto to which Jews were confined for more than three centuries. From Friday, visitors to the city's Jewish museum will be able to explore the jumbled, overcrowded neighbourhood as it was in the second half of the 19th century via an interactive table which provides access to a meticulously reconstructed 3D map that works like Google street view. The ...